Effect of occlusal rehabilitation on spatial memory and hippocampal neurons after long-term loss of molars in rats.
Identifieur interne : 000690 ( PubMed/Curation ); précédent : 000689; suivant : 000691Effect of occlusal rehabilitation on spatial memory and hippocampal neurons after long-term loss of molars in rats.
Auteurs : S. Sakamoto [Japon] ; T. Hara ; A. Kurozumi ; M. Oka ; C. Kuroda-Ishimine ; D. Araki ; S. Iida ; S. MinagiSource :
- Journal of oral rehabilitation [ 1365-2842 ] ; 2014.
Descripteurs français
- KwdFr :
- Animaux, Apprentissage du labyrinthe, Corticostérone (sang), Hippocampe (anatomopathologie), Maxillaire, Molaire, Mâchoire partiellement édentée (rééducation et réadaptation), Mâle, Mémoire spatiale (physiologie), Neurones (anatomopathologie), Rat Wistar, Rats, Résultat thérapeutique, Stress psychologique (sang).
- MESH :
- anatomopathologie : Hippocampe, Neurones.
- physiologie : Mémoire spatiale.
- rééducation et réadaptation : Mâchoire partiellement édentée.
- sang : Corticostérone, Stress psychologique.
- Animaux, Apprentissage du labyrinthe, Maxillaire, Molaire, Mâle, Rat Wistar, Rats, Résultat thérapeutique.
English descriptors
- KwdEn :
- MESH :
- chemical , blood : Corticosterone.
- blood : Stress, Psychological.
- pathology : Hippocampus, Neurons.
- physiology : Spatial Memory.
- rehabilitation : Jaw, Edentulous, Partially.
- Animals, Male, Maxilla, Maze Learning, Molar, Rats, Rats, Wistar, Treatment Outcome.
Abstract
Experimental loss of occlusal support caused by the extraction or grinding of molar teeth has been reported to foment the impairment of learning and memory in laboratory animals. The purpose of this study was to examine the effect of occlusal reconstruction after long-term loss of molars on spatial memory by using 8-arm radial maze and by assessing histopathological changes of neuron density in the hippocampus. Experimental dentures were inserted into the oral cavities of molarless rats to recover the occlusal support. Age-matched groups of control, molarless and denture-wearing rats were trained to perform the maze tasks. The difference of the error incidence in the maze task was evaluated between three groups. The difference of neuron density between three groups was also evaluated at the end of the maze task. Serum corticosterone levels were also measured to estimate the chronic stress, which could be caused by extraction, insertion of the experimental denture or any experimental procedure. The error incidence in the denture-wearing group was significantly higher than that of the control group, but significantly lower than that of the molarless group. Significant differences of neuron density were observed between three groups in each of the hippocampal CA1, CA3 and DG subfields. No significant difference of the serum corticosterone levels between three groups could be observed. From the results of this study, it was suggested that the recovery of occlusal support would bring amelioration of cognitive impairment concomitant with long period loss of molars in rats.
DOI: 10.1111/joor.12198
PubMed: 24909970
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000690
Links to Exploration step
pubmed:24909970Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effect of occlusal rehabilitation on spatial memory and hippocampal neurons after long-term loss of molars in rats.</title><author><name sortKey="Sakamoto, S" sort="Sakamoto, S" uniqKey="Sakamoto S" first="S" last="Sakamoto">S. Sakamoto</name><affiliation wicri:level="1"><nlm:affiliation>Department of Occlusal and Oral Functional Rehabilitation, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Occlusal and Oral Functional Rehabilitation, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama</wicri:regionArea></affiliation></author><author><name sortKey="Hara, T" sort="Hara, T" uniqKey="Hara T" first="T" last="Hara">T. Hara</name></author><author><name sortKey="Kurozumi, A" sort="Kurozumi, A" uniqKey="Kurozumi A" first="A" last="Kurozumi">A. Kurozumi</name></author><author><name sortKey="Oka, M" sort="Oka, M" uniqKey="Oka M" first="M" last="Oka">M. Oka</name></author><author><name sortKey="Kuroda Ishimine, C" sort="Kuroda Ishimine, C" uniqKey="Kuroda Ishimine C" first="C" last="Kuroda-Ishimine">C. Kuroda-Ishimine</name></author><author><name sortKey="Araki, D" sort="Araki, D" uniqKey="Araki D" first="D" last="Araki">D. Araki</name></author><author><name sortKey="Iida, S" sort="Iida, S" uniqKey="Iida S" first="S" last="Iida">S. Iida</name></author><author><name sortKey="Minagi, S" sort="Minagi, S" uniqKey="Minagi S" first="S" last="Minagi">S. Minagi</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24909970</idno><idno type="pmid">24909970</idno><idno type="doi">10.1111/joor.12198</idno><idno type="wicri:Area/PubMed/Corpus">000690</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000690</idno><idno type="wicri:Area/PubMed/Curation">000690</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000690</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Effect of occlusal rehabilitation on spatial memory and hippocampal neurons after long-term loss of molars in rats.</title><author><name sortKey="Sakamoto, S" sort="Sakamoto, S" uniqKey="Sakamoto S" first="S" last="Sakamoto">S. Sakamoto</name><affiliation wicri:level="1"><nlm:affiliation>Department of Occlusal and Oral Functional Rehabilitation, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Occlusal and Oral Functional Rehabilitation, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama</wicri:regionArea></affiliation></author><author><name sortKey="Hara, T" sort="Hara, T" uniqKey="Hara T" first="T" last="Hara">T. Hara</name></author><author><name sortKey="Kurozumi, A" sort="Kurozumi, A" uniqKey="Kurozumi A" first="A" last="Kurozumi">A. Kurozumi</name></author><author><name sortKey="Oka, M" sort="Oka, M" uniqKey="Oka M" first="M" last="Oka">M. Oka</name></author><author><name sortKey="Kuroda Ishimine, C" sort="Kuroda Ishimine, C" uniqKey="Kuroda Ishimine C" first="C" last="Kuroda-Ishimine">C. Kuroda-Ishimine</name></author><author><name sortKey="Araki, D" sort="Araki, D" uniqKey="Araki D" first="D" last="Araki">D. Araki</name></author><author><name sortKey="Iida, S" sort="Iida, S" uniqKey="Iida S" first="S" last="Iida">S. Iida</name></author><author><name sortKey="Minagi, S" sort="Minagi, S" uniqKey="Minagi S" first="S" last="Minagi">S. Minagi</name></author></analytic><series><title level="j">Journal of oral rehabilitation</title><idno type="eISSN">1365-2842</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Corticosterone (blood)</term><term>Hippocampus (pathology)</term><term>Jaw, Edentulous, Partially (rehabilitation)</term><term>Male</term><term>Maxilla</term><term>Maze Learning</term><term>Molar</term><term>Neurons (pathology)</term><term>Rats</term><term>Rats, Wistar</term><term>Spatial Memory (physiology)</term><term>Stress, Psychological (blood)</term><term>Treatment Outcome</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Apprentissage du labyrinthe</term><term>Corticostérone (sang)</term><term>Hippocampe (anatomopathologie)</term><term>Maxillaire</term><term>Molaire</term><term>Mâchoire partiellement édentée (rééducation et réadaptation)</term><term>Mâle</term><term>Mémoire spatiale (physiologie)</term><term>Neurones (anatomopathologie)</term><term>Rat Wistar</term><term>Rats</term><term>Résultat thérapeutique</term><term>Stress psychologique (sang)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Corticosterone</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Hippocampe</term><term>Neurones</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Stress, Psychological</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Hippocampus</term><term>Neurons</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Mémoire spatiale</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Spatial Memory</term></keywords><keywords scheme="MESH" qualifier="rehabilitation" xml:lang="en"><term>Jaw, Edentulous, Partially</term></keywords><keywords scheme="MESH" qualifier="rééducation et réadaptation" xml:lang="fr"><term>Mâchoire partiellement édentée</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Corticostérone</term><term>Stress psychologique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Male</term><term>Maxilla</term><term>Maze Learning</term><term>Molar</term><term>Rats</term><term>Rats, Wistar</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Apprentissage du labyrinthe</term><term>Maxillaire</term><term>Molaire</term><term>Mâle</term><term>Rat Wistar</term><term>Rats</term><term>Résultat thérapeutique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Experimental loss of occlusal support caused by the extraction or grinding of molar teeth has been reported to foment the impairment of learning and memory in laboratory animals. The purpose of this study was to examine the effect of occlusal reconstruction after long-term loss of molars on spatial memory by using 8-arm radial maze and by assessing histopathological changes of neuron density in the hippocampus. Experimental dentures were inserted into the oral cavities of molarless rats to recover the occlusal support. Age-matched groups of control, molarless and denture-wearing rats were trained to perform the maze tasks. The difference of the error incidence in the maze task was evaluated between three groups. The difference of neuron density between three groups was also evaluated at the end of the maze task. Serum corticosterone levels were also measured to estimate the chronic stress, which could be caused by extraction, insertion of the experimental denture or any experimental procedure. The error incidence in the denture-wearing group was significantly higher than that of the control group, but significantly lower than that of the molarless group. Significant differences of neuron density were observed between three groups in each of the hippocampal CA1, CA3 and DG subfields. No significant difference of the serum corticosterone levels between three groups could be observed. From the results of this study, it was suggested that the recovery of occlusal support would bring amelioration of cognitive impairment concomitant with long period loss of molars in rats.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24909970</PMID><DateCompleted><Year>2015</Year><Month>05</Month><Day>26</Day></DateCompleted><DateRevised><Year>2014</Year><Month>09</Month><Day>12</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1365-2842</ISSN><JournalIssue CitedMedium="Internet"><Volume>41</Volume><Issue>10</Issue><PubDate><Year>2014</Year><Month>Oct</Month></PubDate></JournalIssue><Title>Journal of oral rehabilitation</Title><ISOAbbreviation>J Oral Rehabil</ISOAbbreviation></Journal><ArticleTitle>Effect of occlusal rehabilitation on spatial memory and hippocampal neurons after long-term loss of molars in rats.</ArticleTitle><Pagination><MedlinePgn>715-22</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/joor.12198</ELocationID><Abstract><AbstractText>Experimental loss of occlusal support caused by the extraction or grinding of molar teeth has been reported to foment the impairment of learning and memory in laboratory animals. The purpose of this study was to examine the effect of occlusal reconstruction after long-term loss of molars on spatial memory by using 8-arm radial maze and by assessing histopathological changes of neuron density in the hippocampus. Experimental dentures were inserted into the oral cavities of molarless rats to recover the occlusal support. Age-matched groups of control, molarless and denture-wearing rats were trained to perform the maze tasks. The difference of the error incidence in the maze task was evaluated between three groups. The difference of neuron density between three groups was also evaluated at the end of the maze task. Serum corticosterone levels were also measured to estimate the chronic stress, which could be caused by extraction, insertion of the experimental denture or any experimental procedure. The error incidence in the denture-wearing group was significantly higher than that of the control group, but significantly lower than that of the molarless group. Significant differences of neuron density were observed between three groups in each of the hippocampal CA1, CA3 and DG subfields. No significant difference of the serum corticosterone levels between three groups could be observed. From the results of this study, it was suggested that the recovery of occlusal support would bring amelioration of cognitive impairment concomitant with long period loss of molars in rats.</AbstractText><CopyrightInformation>© 2014 John Wiley & Sons Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Sakamoto</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Occlusal and Oral Functional Rehabilitation, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hara</LastName><ForeName>T</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Kurozumi</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Oka</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Kuroda-Ishimine</LastName><ForeName>C</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Araki</LastName><ForeName>D</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Iida</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Minagi</LastName><ForeName>S</ForeName><Initials>S</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>06</Month><Day>07</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Oral Rehabil</MedlineTA><NlmUniqueID>0433604</NlmUniqueID><ISSNLinking>0305-182X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>W980KJ009P</RegistryNumber><NameOfSubstance UI="D003345">Corticosterone</NameOfSubstance></Chemical></ChemicalList><CitationSubset>D</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003345" MajorTopicYN="N">Corticosterone</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006624" MajorTopicYN="N">Hippocampus</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007576" MajorTopicYN="N">Jaw, Edentulous, Partially</DescriptorName><QualifierName UI="Q000534" MajorTopicYN="Y">rehabilitation</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008437" MajorTopicYN="N">Maxilla</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018782" MajorTopicYN="N">Maze Learning</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008963" MajorTopicYN="N">Molar</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009474" MajorTopicYN="N">Neurons</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D051381" MajorTopicYN="N">Rats</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017208" MajorTopicYN="N">Rats, Wistar</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D065852" MajorTopicYN="N">Spatial Memory</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013315" MajorTopicYN="N">Stress, Psychological</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">dental occlusal wear</Keyword><Keyword MajorTopicYN="N">hippocampus</Keyword><Keyword MajorTopicYN="N">maze learning</Keyword><Keyword MajorTopicYN="N">neurons</Keyword><Keyword MajorTopicYN="N">rats</Keyword><Keyword MajorTopicYN="N">toothless</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="accepted"><Year>2014</Year><Month>05</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>6</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>6</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>5</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24909970</ArticleId><ArticleId IdType="doi">10.1111/joor.12198</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000690 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 000690 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= PubMed
|étape= Curation
|type= RBID
|clé= pubmed:24909970
|texte= Effect of occlusal rehabilitation on spatial memory and hippocampal neurons after long-term loss of molars in rats.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:24909970" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a EdenteV2
| This area was generated with Dilib version V0.6.32. |  |