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Histological observations of a bilateral maxillary sinus floor elevation 6 and 12 months after grafting with osteogenic protein-1 device.

Identifieur interne : 003817 ( PubMed/Corpus ); précédent : 003816; suivant : 003818

Histological observations of a bilateral maxillary sinus floor elevation 6 and 12 months after grafting with osteogenic protein-1 device.

Auteurs : H H Groenveld ; J P Van Den Bergh ; P. Holzmann ; C M Ten Bruggenkate ; D B Tuinzing ; E H Burger

Source :

RBID : pubmed:10599913

English descriptors

Abstract

The purpose of this case study was to analyze the tissue formed in a maxillary sinus, 6 and 12 months after grafting with recombinant human osteogenic protein-1 (OP-1) linked to a collagen carrier of bovine origin.

PubMed: 10599913

Links to Exploration step

pubmed:10599913

Le document en format XML

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<title xml:lang="en">Histological observations of a bilateral maxillary sinus floor elevation 6 and 12 months after grafting with osteogenic protein-1 device.</title>
<author>
<name sortKey="Groenveld, H H" sort="Groenveld, H H" uniqKey="Groenveld H" first="H H" last="Groenveld">H H Groenveld</name>
<affiliation>
<nlm:affiliation>Department of Oral Cell Biology, ACTA, Vrije Universiteit, Amsterdam, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Van Den Bergh, J P" sort="Van Den Bergh, J P" uniqKey="Van Den Bergh J" first="J P" last="Van Den Bergh">J P Van Den Bergh</name>
</author>
<author>
<name sortKey="Holzmann, P" sort="Holzmann, P" uniqKey="Holzmann P" first="P" last="Holzmann">P. Holzmann</name>
</author>
<author>
<name sortKey="Ten Bruggenkate, C M" sort="Ten Bruggenkate, C M" uniqKey="Ten Bruggenkate C" first="C M" last="Ten Bruggenkate">C M Ten Bruggenkate</name>
</author>
<author>
<name sortKey="Tuinzing, D B" sort="Tuinzing, D B" uniqKey="Tuinzing D" first="D B" last="Tuinzing">D B Tuinzing</name>
</author>
<author>
<name sortKey="Burger, E H" sort="Burger, E H" uniqKey="Burger E" first="E H" last="Burger">E H Burger</name>
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<title xml:lang="en">Histological observations of a bilateral maxillary sinus floor elevation 6 and 12 months after grafting with osteogenic protein-1 device.</title>
<author>
<name sortKey="Groenveld, H H" sort="Groenveld, H H" uniqKey="Groenveld H" first="H H" last="Groenveld">H H Groenveld</name>
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<nlm:affiliation>Department of Oral Cell Biology, ACTA, Vrije Universiteit, Amsterdam, The Netherlands.</nlm:affiliation>
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<name sortKey="Van Den Bergh, J P" sort="Van Den Bergh, J P" uniqKey="Van Den Bergh J" first="J P" last="Van Den Bergh">J P Van Den Bergh</name>
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<name sortKey="Holzmann, P" sort="Holzmann, P" uniqKey="Holzmann P" first="P" last="Holzmann">P. Holzmann</name>
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<name sortKey="Ten Bruggenkate, C M" sort="Ten Bruggenkate, C M" uniqKey="Ten Bruggenkate C" first="C M" last="Ten Bruggenkate">C M Ten Bruggenkate</name>
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<name sortKey="Tuinzing, D B" sort="Tuinzing, D B" uniqKey="Tuinzing D" first="D B" last="Tuinzing">D B Tuinzing</name>
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<name sortKey="Burger, E H" sort="Burger, E H" uniqKey="Burger E" first="E H" last="Burger">E H Burger</name>
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<title level="j">Journal of clinical periodontology</title>
<idno type="ISSN">0303-6979</idno>
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<term>Biopsy</term>
<term>Bone Morphogenetic Protein 7</term>
<term>Bone Morphogenetic Proteins (therapeutic use)</term>
<term>Bone Transplantation (methods)</term>
<term>Collagen</term>
<term>Drug Carriers</term>
<term>Female</term>
<term>Humans</term>
<term>Jaw, Edentulous (pathology)</term>
<term>Jaw, Edentulous (surgery)</term>
<term>Maxilla</term>
<term>Maxillary Sinus (pathology)</term>
<term>Maxillary Sinus (surgery)</term>
<term>Middle Aged</term>
<term>Oral Surgical Procedures, Preprosthetic (methods)</term>
<term>Recombinant Proteins (therapeutic use)</term>
<term>Time Factors</term>
<term>Transforming Growth Factor beta (therapeutic use)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en">
<term>Bone Morphogenetic Proteins</term>
<term>Recombinant Proteins</term>
<term>Transforming Growth Factor beta</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en">
<term>Bone Morphogenetic Protein 7</term>
<term>Collagen</term>
<term>Drug Carriers</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Bone Transplantation</term>
<term>Oral Surgical Procedures, Preprosthetic</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Jaw, Edentulous</term>
<term>Maxillary Sinus</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Jaw, Edentulous</term>
<term>Maxillary Sinus</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Biopsy</term>
<term>Female</term>
<term>Humans</term>
<term>Maxilla</term>
<term>Middle Aged</term>
<term>Time Factors</term>
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<front>
<div type="abstract" xml:lang="en">The purpose of this case study was to analyze the tissue formed in a maxillary sinus, 6 and 12 months after grafting with recombinant human osteogenic protein-1 (OP-1) linked to a collagen carrier of bovine origin.</div>
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<Year>2000</Year>
<Month>01</Month>
<Day>06</Day>
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<Day>21</Day>
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<ISSN IssnType="Print">0303-6979</ISSN>
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<Volume>26</Volume>
<Issue>12</Issue>
<PubDate>
<Year>1999</Year>
<Month>Dec</Month>
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<Title>Journal of clinical periodontology</Title>
<ISOAbbreviation>J. Clin. Periodontol.</ISOAbbreviation>
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<ArticleTitle>Histological observations of a bilateral maxillary sinus floor elevation 6 and 12 months after grafting with osteogenic protein-1 device.</ArticleTitle>
<Pagination>
<MedlinePgn>841-6</MedlinePgn>
</Pagination>
<Abstract>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The purpose of this case study was to analyze the tissue formed in a maxillary sinus, 6 and 12 months after grafting with recombinant human osteogenic protein-1 (OP-1) linked to a collagen carrier of bovine origin.</AbstractText>
<AbstractText Label="PATIENT AND METHODS" NlmCategory="METHODS">A 49-year-old woman referred for bilateral sinus floor elevation, was grafted with an OP-1 device. After 6 months, a biopsy was taken from one of the grafted areas. After 12 months, during implant placement, 5 biopsies were taken from the grafted area and the maxillary host bone. Biopsies were processed without decalcification for histological analyses.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The biopsy taken after 6 months contained newly formed bone, fibrotic tissue and device remnants. After 12 months, however, bone was absent from all biopsies which were taken from the grafted area, while particles of the collagen carrier were still abundant. Inflammatory cells were observed between remnants of the collagen carrier in the grafted area.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">This study indicates that an onset of new bone formation, which was observed after 6 months, did not persist. 12 months after grafting no bone was present in the biopsies from the grafted area, while the collagen carrier had remained. Lack of mechanical loading, as a result of postponing implant placement from 6 to 12 months, may have resulted in resorption of the emerging bone which was present 6 months after grafting.</AbstractText>
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<LastName>Groenveld</LastName>
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<Affiliation>Department of Oral Cell Biology, ACTA, Vrije Universiteit, Amsterdam, The Netherlands.</Affiliation>
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<NameOfSubstance UI="C525819">BMP7 protein, human</NameOfSubstance>
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<NameOfSubstance UI="D055419">Bone Morphogenetic Protein 7</NameOfSubstance>
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<DescriptorName UI="D003094" MajorTopicYN="N">Collagen</DescriptorName>
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<DescriptorName UI="D008437" MajorTopicYN="N">Maxilla</DescriptorName>
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<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
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