Randomized multicenter comparison of two coatings of intramobile cylinder implants in 313 partially edentulous mandibles followed up for 5 years.
Identifieur interne : 003118 ( PubMed/Corpus ); précédent : 003117; suivant : 003119Randomized multicenter comparison of two coatings of intramobile cylinder implants in 313 partially edentulous mandibles followed up for 5 years.
Auteurs : Jochen Mau ; Alexandra Behneke ; Nikolaus Behneke ; Claus Udo Fritzemeier ; German Gomez-Roman ; Bernd D'Hoedt ; Hubertus Spiekermann ; Volker Strunz ; Mei YongSource :
- Clinical oral implants research [ 0905-7161 ] ; 2002.
English descriptors
- KwdEn :
- Adult, Alveolar Bone Loss (classification), Biocompatible Materials (chemistry), Chi-Square Distribution, Coated Materials, Biocompatible (chemistry), Dental Abutments, Dental Implants, Dental Plaque Index, Dental Prosthesis Design, Dental Prosthesis, Implant-Supported, Dental Restoration Failure, Denture, Partial, Fixed, Durapatite (chemistry), Female, Follow-Up Studies, Humans, Jaw, Edentulous, Partially (rehabilitation), Jaw, Edentulous, Partially (surgery), Linear Models, Male, Mandible (surgery), Osseointegration, Periodontal Index, Periodontal Pocket (classification), Proportional Hazards Models, Prospective Studies, Statistics, Nonparametric, Titanium (chemistry), Treatment Outcome.
- MESH :
- chemical , chemistry : Biocompatible Materials, Coated Materials, Biocompatible, Durapatite, Titanium.
- classification : Alveolar Bone Loss, Periodontal Pocket.
- rehabilitation : Jaw, Edentulous, Partially.
- surgery : Jaw, Edentulous, Partially, Mandible.
- Adult, Chi-Square Distribution, Dental Abutments, Dental Implants, Dental Plaque Index, Dental Prosthesis Design, Dental Prosthesis, Implant-Supported, Dental Restoration Failure, Denture, Partial, Fixed, Female, Follow-Up Studies, Humans, Linear Models, Male, Osseointegration, Periodontal Index, Proportional Hazards Models, Prospective Studies, Statistics, Nonparametric, Treatment Outcome.
Abstract
Intramobile cylinder (IMZ) implants with either of two coatings, hydroxyapatite (HA) or titanium plasma-flame (TPF), as distal abutments for combined tooth implant-supported restorations, were compared in 313 partially edentulous mandibles with respect to postprosthetical failure patterns and complication frequencies in a randomized multicenter clinical trial. Within the treatment protocols, the two coatings do not show evidence of different efficacy with respect to occurrence of postprosthetical integration deficiency (ID) or functional deficiency (FD). Statistical equivalence for an absolute effect of +/-15% in event-free survival could only be demonstrated for FD, not for ID, however. Intent-to-treat and per-protocol population analyses gave consistent results. Hazards of occurrence of ID and FD, adjusted for years of follow-up, were estimated for ID as 7% per year (95%CI 4-10% per year) with HA and 5% per year (95%CI 3-7% per year) with TPF, and for FD as 5% per year (95%CI 3-7% per year) with HA and 4% per year (95%CI 2-6% per year) with TPF. The 5-year cumulative success rates for no ID were 69.5% (95%CI 58-81%) with HA and 82.2% (95%CI 74-91%) with TPF. With respect to frequencies of complications, there was no relevant statistically significant difference between the two coatings.
PubMed: 12453124
Links to Exploration step
pubmed:12453124Le document en format XML
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<affiliation><nlm:affiliation>Department of Statistics in Medicine, University Hospital Duesseldorf, Duesseldorf, Germany.</nlm:affiliation>
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<author><name sortKey="Behneke, Alexandra" sort="Behneke, Alexandra" uniqKey="Behneke A" first="Alexandra" last="Behneke">Alexandra Behneke</name>
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<author><name sortKey="Behneke, Nikolaus" sort="Behneke, Nikolaus" uniqKey="Behneke N" first="Nikolaus" last="Behneke">Nikolaus Behneke</name>
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<author><name sortKey="Fritzemeier, Claus Udo" sort="Fritzemeier, Claus Udo" uniqKey="Fritzemeier C" first="Claus Udo" last="Fritzemeier">Claus Udo Fritzemeier</name>
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<author><name sortKey="Gomez Roman, German" sort="Gomez Roman, German" uniqKey="Gomez Roman G" first="German" last="Gomez-Roman">German Gomez-Roman</name>
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<author><name sortKey="D Hoedt, Bernd" sort="D Hoedt, Bernd" uniqKey="D Hoedt B" first="Bernd" last="D'Hoedt">Bernd D'Hoedt</name>
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<term>Coated Materials, Biocompatible (chemistry)</term>
<term>Dental Abutments</term>
<term>Dental Implants</term>
<term>Dental Plaque Index</term>
<term>Dental Prosthesis Design</term>
<term>Dental Prosthesis, Implant-Supported</term>
<term>Dental Restoration Failure</term>
<term>Denture, Partial, Fixed</term>
<term>Durapatite (chemistry)</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Jaw, Edentulous, Partially (rehabilitation)</term>
<term>Jaw, Edentulous, Partially (surgery)</term>
<term>Linear Models</term>
<term>Male</term>
<term>Mandible (surgery)</term>
<term>Osseointegration</term>
<term>Periodontal Index</term>
<term>Periodontal Pocket (classification)</term>
<term>Proportional Hazards Models</term>
<term>Prospective Studies</term>
<term>Statistics, Nonparametric</term>
<term>Titanium (chemistry)</term>
<term>Treatment Outcome</term>
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<term>Durapatite</term>
<term>Titanium</term>
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<keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Alveolar Bone Loss</term>
<term>Periodontal Pocket</term>
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<keywords scheme="MESH" qualifier="rehabilitation" xml:lang="en"><term>Jaw, Edentulous, Partially</term>
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<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Jaw, Edentulous, Partially</term>
<term>Mandible</term>
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<term>Dental Prosthesis, Implant-Supported</term>
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<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Linear Models</term>
<term>Male</term>
<term>Osseointegration</term>
<term>Periodontal Index</term>
<term>Proportional Hazards Models</term>
<term>Prospective Studies</term>
<term>Statistics, Nonparametric</term>
<term>Treatment Outcome</term>
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<front><div type="abstract" xml:lang="en">Intramobile cylinder (IMZ) implants with either of two coatings, hydroxyapatite (HA) or titanium plasma-flame (TPF), as distal abutments for combined tooth implant-supported restorations, were compared in 313 partially edentulous mandibles with respect to postprosthetical failure patterns and complication frequencies in a randomized multicenter clinical trial. Within the treatment protocols, the two coatings do not show evidence of different efficacy with respect to occurrence of postprosthetical integration deficiency (ID) or functional deficiency (FD). Statistical equivalence for an absolute effect of +/-15% in event-free survival could only be demonstrated for FD, not for ID, however. Intent-to-treat and per-protocol population analyses gave consistent results. Hazards of occurrence of ID and FD, adjusted for years of follow-up, were estimated for ID as 7% per year (95%CI 4-10% per year) with HA and 5% per year (95%CI 3-7% per year) with TPF, and for FD as 5% per year (95%CI 3-7% per year) with HA and 4% per year (95%CI 2-6% per year) with TPF. The 5-year cumulative success rates for no ID were 69.5% (95%CI 58-81%) with HA and 82.2% (95%CI 74-91%) with TPF. With respect to frequencies of complications, there was no relevant statistically significant difference between the two coatings.</div>
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<Abstract><AbstractText>Intramobile cylinder (IMZ) implants with either of two coatings, hydroxyapatite (HA) or titanium plasma-flame (TPF), as distal abutments for combined tooth implant-supported restorations, were compared in 313 partially edentulous mandibles with respect to postprosthetical failure patterns and complication frequencies in a randomized multicenter clinical trial. Within the treatment protocols, the two coatings do not show evidence of different efficacy with respect to occurrence of postprosthetical integration deficiency (ID) or functional deficiency (FD). Statistical equivalence for an absolute effect of +/-15% in event-free survival could only be demonstrated for FD, not for ID, however. Intent-to-treat and per-protocol population analyses gave consistent results. Hazards of occurrence of ID and FD, adjusted for years of follow-up, were estimated for ID as 7% per year (95%CI 4-10% per year) with HA and 5% per year (95%CI 3-7% per year) with TPF, and for FD as 5% per year (95%CI 3-7% per year) with HA and 4% per year (95%CI 2-6% per year) with TPF. The 5-year cumulative success rates for no ID were 69.5% (95%CI 58-81%) with HA and 82.2% (95%CI 74-91%) with TPF. With respect to frequencies of complications, there was no relevant statistically significant difference between the two coatings.</AbstractText>
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