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Mineralized bone loss in partially edentulous trabeculae of ovariectomized rabbit mandibles.

Identifieur interne : 002D18 ( PubMed/Corpus ); précédent : 002D17; suivant : 002D19

Mineralized bone loss in partially edentulous trabeculae of ovariectomized rabbit mandibles.

Auteurs : T. Cao ; T. Shirota ; K. Ohno ; K I Michi

Source :

RBID : pubmed:14687226

English descriptors

Abstract

The purpose of this study was to evaluate trabeculae changes in partially edentulous bone in ovariectomized rabbits.

PubMed: 14687226

Links to Exploration step

pubmed:14687226

Le document en format XML

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<title xml:lang="en">Mineralized bone loss in partially edentulous trabeculae of ovariectomized rabbit mandibles.</title>
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<name sortKey="Cao, T" sort="Cao, T" uniqKey="Cao T" first="T" last="Cao">T. Cao</name>
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<nlm:affiliation>Faculty of Dentistry, National University of Singapore, National University Hospital, 119074. dencaot@nus.edu.sg</nlm:affiliation>
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<name sortKey="Shirota, T" sort="Shirota, T" uniqKey="Shirota T" first="T" last="Shirota">T. Shirota</name>
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<name sortKey="Ohno, K" sort="Ohno, K" uniqKey="Ohno K" first="K" last="Ohno">K. Ohno</name>
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<name sortKey="Michi, K I" sort="Michi, K I" uniqKey="Michi K" first="K I" last="Michi">K I Michi</name>
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<title level="j">Journal of periodontal research</title>
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<term>Analysis of Variance</term>
<term>Animals</term>
<term>Bone Density (physiology)</term>
<term>Bone Matrix (pathology)</term>
<term>Bone Resorption (physiopathology)</term>
<term>Female</term>
<term>Jaw, Edentulous, Partially (complications)</term>
<term>Jaw, Edentulous, Partially (physiopathology)</term>
<term>Mandibular Diseases (etiology)</term>
<term>Mandibular Diseases (physiopathology)</term>
<term>Osteogenesis (physiology)</term>
<term>Ovariectomy</term>
<term>Ovary (physiology)</term>
<term>Rabbits</term>
<term>Risk Factors</term>
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<term>Jaw, Edentulous, Partially</term>
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<term>Mandibular Diseases</term>
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<term>Bone Matrix</term>
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<term>Jaw, Edentulous, Partially</term>
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<term>Analysis of Variance</term>
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<div type="abstract" xml:lang="en">The purpose of this study was to evaluate trabeculae changes in partially edentulous bone in ovariectomized rabbits.</div>
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<Year>2004</Year>
<Month>03</Month>
<Day>11</Day>
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<Year>2006</Year>
<Month>11</Month>
<Day>15</Day>
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<ISSN IssnType="Print">0022-3484</ISSN>
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<Volume>39</Volume>
<Issue>1</Issue>
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<Year>2004</Year>
<Month>Feb</Month>
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<Title>Journal of periodontal research</Title>
<ISOAbbreviation>J. Periodont. Res.</ISOAbbreviation>
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<ArticleTitle>Mineralized bone loss in partially edentulous trabeculae of ovariectomized rabbit mandibles.</ArticleTitle>
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<MedlinePgn>37-41</MedlinePgn>
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<Abstract>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The purpose of this study was to evaluate trabeculae changes in partially edentulous bone in ovariectomized rabbits.</AbstractText>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Numerous clinical studies have suggested that the greater risk for oral bone loss in females may be correlated with osteoporosis after menopause. Knowledge of trabecular changes in partially edentulous bone in animals with loss of ovarian function may be beneficial in the diagnosis and treatment of partially edentulous patients of postmenopausal women.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Twelve adult female Japanese white rabbits were examined. The mandibular incisors were initially extracted to simulate the partially edentulous bone. Six animals were bilaterally ovariectomized and the other six sham-ovariectomized 12 weeks after tooth extraction. The partially edentulous parts of distal mandibular bodies were processed undecalcified 12 weeks after ovariectomized or sham-ovariectomized surgeries and examined by quantitative trabecular bone histomorphometry.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">In ovariectomized rabbits, there were significant increases in trabecular separation, osteoid volume, osteoid thickness, osteoid width, eroded surface, and mineral apposition rate, and a significant decrease in trabecular number.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The results of sparser trabecular structure, more trabecular osteoid, and increased trabecular bone turnover demonstrate mineralized bone loss in partially edentulous trabeculae of ovariectomized rabbit mandibles and suggest that the same loss may occur in postmenopausal women.</AbstractText>
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