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Reconstruction of the severely resorbed maxilla with autogenous bone, platelet-rich plasma, and implants: 1-year results of a controlled prospective 5-year study.

Identifieur interne : 002A57 ( PubMed/Corpus ); précédent : 002A56; suivant : 002A58

Reconstruction of the severely resorbed maxilla with autogenous bone, platelet-rich plasma, and implants: 1-year results of a controlled prospective 5-year study.

Auteurs : Andreas Thor ; Karin Wannfors ; Lars Sennerby ; Lars Rasmusson

Source :

RBID : pubmed:16336912

English descriptors

Abstract

Prosthetic treatment of the edentulous maxilla may require bone augmentation to enable placement and integration of dental implants. This constitutes a complex healing situation, and resorption of the grafted bone and failure of the implants often occur. The application of autogenous platelet-rich plasma (PRP) has been suggested to improve incorporation and preservation of bone grafts.

PubMed: 16336912

Links to Exploration step

pubmed:16336912

Le document en format XML

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<title xml:lang="en">Reconstruction of the severely resorbed maxilla with autogenous bone, platelet-rich plasma, and implants: 1-year results of a controlled prospective 5-year study.</title>
<author>
<name sortKey="Thor, Andreas" sort="Thor, Andreas" uniqKey="Thor A" first="Andreas" last="Thor">Andreas Thor</name>
<affiliation>
<nlm:affiliation>Department of Surgical Sciences, Oral and Maxillofacial Surgery, Uppsala University Hospital, Sweden. andreas.thor@lul.se</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Wannfors, Karin" sort="Wannfors, Karin" uniqKey="Wannfors K" first="Karin" last="Wannfors">Karin Wannfors</name>
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<author>
<name sortKey="Sennerby, Lars" sort="Sennerby, Lars" uniqKey="Sennerby L" first="Lars" last="Sennerby">Lars Sennerby</name>
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<author>
<name sortKey="Rasmusson, Lars" sort="Rasmusson, Lars" uniqKey="Rasmusson L" first="Lars" last="Rasmusson">Lars Rasmusson</name>
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<title xml:lang="en">Reconstruction of the severely resorbed maxilla with autogenous bone, platelet-rich plasma, and implants: 1-year results of a controlled prospective 5-year study.</title>
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<name sortKey="Thor, Andreas" sort="Thor, Andreas" uniqKey="Thor A" first="Andreas" last="Thor">Andreas Thor</name>
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<nlm:affiliation>Department of Surgical Sciences, Oral and Maxillofacial Surgery, Uppsala University Hospital, Sweden. andreas.thor@lul.se</nlm:affiliation>
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<name sortKey="Wannfors, Karin" sort="Wannfors, Karin" uniqKey="Wannfors K" first="Karin" last="Wannfors">Karin Wannfors</name>
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<name sortKey="Sennerby, Lars" sort="Sennerby, Lars" uniqKey="Sennerby L" first="Lars" last="Sennerby">Lars Sennerby</name>
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<name sortKey="Rasmusson, Lars" sort="Rasmusson, Lars" uniqKey="Rasmusson L" first="Lars" last="Rasmusson">Lars Rasmusson</name>
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<title level="j">Clinical implant dentistry and related research</title>
<idno type="ISSN">1523-0899</idno>
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<term>Adult</term>
<term>Aged</term>
<term>Alveolar Ridge Augmentation (methods)</term>
<term>Blood Platelets (physiology)</term>
<term>Bone Resorption (surgery)</term>
<term>Bone Transplantation (methods)</term>
<term>Bone Transplantation (pathology)</term>
<term>Dental Abutments</term>
<term>Dental Implants</term>
<term>Dental Restoration Failure</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Graft Survival</term>
<term>Humans</term>
<term>Jaw, Edentulous (rehabilitation)</term>
<term>Jaw, Edentulous (surgery)</term>
<term>Male</term>
<term>Maxilla (pathology)</term>
<term>Maxilla (surgery)</term>
<term>Maxillary Diseases (pathology)</term>
<term>Maxillary Diseases (surgery)</term>
<term>Middle Aged</term>
<term>Osseointegration (physiology)</term>
<term>Plasma</term>
<term>Platelet Transfusion</term>
<term>Prospective Studies</term>
<term>Wound Healing (physiology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en">
<term>Dental Implants</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Alveolar Ridge Augmentation</term>
<term>Bone Transplantation</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Bone Transplantation</term>
<term>Maxilla</term>
<term>Maxillary Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en">
<term>Blood Platelets</term>
<term>Osseointegration</term>
<term>Wound Healing</term>
</keywords>
<keywords scheme="MESH" qualifier="rehabilitation" xml:lang="en">
<term>Jaw, Edentulous</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Bone Resorption</term>
<term>Jaw, Edentulous</term>
<term>Maxilla</term>
<term>Maxillary Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Dental Abutments</term>
<term>Dental Restoration Failure</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Graft Survival</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Plasma</term>
<term>Platelet Transfusion</term>
<term>Prospective Studies</term>
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<front>
<div type="abstract" xml:lang="en">Prosthetic treatment of the edentulous maxilla may require bone augmentation to enable placement and integration of dental implants. This constitutes a complex healing situation, and resorption of the grafted bone and failure of the implants often occur. The application of autogenous platelet-rich plasma (PRP) has been suggested to improve incorporation and preservation of bone grafts.</div>
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<PMID Version="1">16336912</PMID>
<DateCompleted>
<Year>2006</Year>
<Month>04</Month>
<Day>28</Day>
</DateCompleted>
<DateRevised>
<Year>2006</Year>
<Month>11</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Print">
<Journal>
<ISSN IssnType="Print">1523-0899</ISSN>
<JournalIssue CitedMedium="Print">
<Volume>7</Volume>
<Issue>4</Issue>
<PubDate>
<Year>2005</Year>
</PubDate>
</JournalIssue>
<Title>Clinical implant dentistry and related research</Title>
<ISOAbbreviation>Clin Implant Dent Relat Res</ISOAbbreviation>
</Journal>
<ArticleTitle>Reconstruction of the severely resorbed maxilla with autogenous bone, platelet-rich plasma, and implants: 1-year results of a controlled prospective 5-year study.</ArticleTitle>
<Pagination>
<MedlinePgn>209-20</MedlinePgn>
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<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Prosthetic treatment of the edentulous maxilla may require bone augmentation to enable placement and integration of dental implants. This constitutes a complex healing situation, and resorption of the grafted bone and failure of the implants often occur. The application of autogenous platelet-rich plasma (PRP) has been suggested to improve incorporation and preservation of bone grafts.</AbstractText>
<AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">The aim of this controlled clinical study was to evaluate whether PRP in conjunction with grafting of particulated autogenous bone to the maxilla could improve the integration and clinical function of dental implants. An additional aim was to compare block bone grafts without PRP with PRP-treated particulated bone.</AbstractText>
<AbstractText Label="MATERIAL AND METHODS" NlmCategory="METHODS">Nineteen consecutive patients were included in the study and treated with iliac bone grafts and dental implants in the maxilla according to a split-mouth design. In the anterior maxilla, particulated bone mixed with PRP (test) was compared with onlay block grafts without additional PRP (control). In the posterior maxilla, particulated bone grafts with (test) or without (control) PRP were placed as sinus inlay grafts. After 6 months of healing, 152 implants (8 implants/patient) (TiOblast, Astra Tech AB, Mölndal, Sweden) were placed. Test (PRP; 76 implants) and non-PRP (76 implants) sides were evaluated and compared by implant survival rate, marginal bone level, and implant stability using resonance frequency analysis (RFA) during 1 year in function.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Two control implants in control sites in two patients were lost at abutment connection. After 1 year in function, no further implants were lost, giving an overall survival rate of 98.7%. The marginal bone level measurements showed no significant differences, although there was a tendency toward less resorption on PRP sides. RFA measurements showed statistically significantly higher implant stability quotient values for PRP sites at abutment connection in the anterior but not in the posterior regions.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The present clinical study showed that a high implant survival rate and stable marginal bone conditions can be achieved after 1 year of loading in the maxilla following autogenous bone grafting whether or not PRP is used. RFA measurements revealed differences at abutment connection, which could be explained by the type of graft rather than as an effect of PRP. Although no obvious positive effects of PRP on bone graft healing could be demonstrated, the handling of the particulated bone grafts was improved.</AbstractText>
</Abstract>
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<LastName>Thor</LastName>
<ForeName>Andreas</ForeName>
<Initials>A</Initials>
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<Affiliation>Department of Surgical Sciences, Oral and Maxillofacial Surgery, Uppsala University Hospital, Sweden. andreas.thor@lul.se</Affiliation>
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<LastName>Wannfors</LastName>
<ForeName>Karin</ForeName>
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<LastName>Sennerby</LastName>
<ForeName>Lars</ForeName>
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<LastName>Rasmusson</LastName>
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<Language>eng</Language>
<PublicationTypeList>
<PublicationType UI="D003160">Comparative Study</PublicationType>
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<Country>United States</Country>
<MedlineTA>Clin Implant Dent Relat Res</MedlineTA>
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<NameOfSubstance UI="D015921">Dental Implants</NameOfSubstance>
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<MeshHeading>
<DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
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<DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
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<MeshHeading>
<DescriptorName UI="D000540" MajorTopicYN="N">Alveolar Ridge Augmentation</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
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<DescriptorName UI="D001792" MajorTopicYN="N">Blood Platelets</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
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<DescriptorName UI="D001862" MajorTopicYN="N">Bone Resorption</DescriptorName>
<QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName>
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<DescriptorName UI="D016025" MajorTopicYN="Y">Bone Transplantation</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName>
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<DescriptorName UI="D000044" MajorTopicYN="N">Dental Abutments</DescriptorName>
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<DescriptorName UI="D015921" MajorTopicYN="Y">Dental Implants</DescriptorName>
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<DescriptorName UI="D019232" MajorTopicYN="N">Dental Restoration Failure</DescriptorName>
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<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
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<DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName>
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<MeshHeading>
<DescriptorName UI="D006085" MajorTopicYN="N">Graft Survival</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D007575" MajorTopicYN="N">Jaw, Edentulous</DescriptorName>
<QualifierName UI="Q000534" MajorTopicYN="N">rehabilitation</QualifierName>
<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008437" MajorTopicYN="N">Maxilla</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
<QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008439" MajorTopicYN="N">Maxillary Diseases</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
<QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D016348" MajorTopicYN="N">Osseointegration</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D010949" MajorTopicYN="N">Plasma</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D017713" MajorTopicYN="Y">Platelet Transfusion</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D014945" MajorTopicYN="N">Wound Healing</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
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