Microbiota around teeth and dental implants in periodontally healthy, partially edentulous patients: is pre-implant microbiological testing relevant?
Identifieur interne : 001874 ( PubMed/Corpus ); précédent : 001873; suivant : 001875Microbiota around teeth and dental implants in periodontally healthy, partially edentulous patients: is pre-implant microbiological testing relevant?
Auteurs : Leo Meijndert ; Wil A. Van Der Reijden ; Gerry M. Raghoebar ; Henny J A. Meijer ; Arjan VissinkSource :
- European journal of oral sciences [ 1600-0722 ] ; 2010.
English descriptors
- KwdEn :
- Adolescent, Adult, Aggregatibacter actinomycetemcomitans (isolation & purification), Anti-Bacterial Agents (therapeutic use), Bacterial Load, Bacteroides (isolation & purification), Biofilms, Campylobacter rectus (isolation & purification), Dental Implants, Single-Tooth (microbiology), Dental Plaque (microbiology), Female, Follow-Up Studies, Fusobacterium nucleatum (isolation & purification), Gram-Negative Bacteria (classification), Humans, Jaw, Edentulous, Partially (microbiology), Jaw, Edentulous, Partially (rehabilitation), Male, Maxilla (surgery), Middle Aged, Patient Care Planning, Peptostreptococcus (isolation & purification), Periodontal Pocket (microbiology), Periodontium (microbiology), Porphyromonas gingivalis (isolation & purification), Preoperative Care, Prevotella intermedia (isolation & purification), Tooth (microbiology), Young Adult.
- MESH :
- chemical , therapeutic use : Anti-Bacterial Agents.
- classification : Gram-Negative Bacteria.
- isolation & purification : Aggregatibacter actinomycetemcomitans, Bacteroides, Campylobacter rectus, Fusobacterium nucleatum, Peptostreptococcus, Porphyromonas gingivalis, Prevotella intermedia.
- microbiology : Dental Implants, Single-Tooth, Dental Plaque, Jaw, Edentulous, Partially, Periodontal Pocket, Periodontium, Tooth.
- rehabilitation : Jaw, Edentulous, Partially.
- surgery : Maxilla.
- Adolescent, Adult, Bacterial Load, Biofilms, Female, Follow-Up Studies, Humans, Male, Middle Aged, Patient Care Planning, Preoperative Care, Young Adult.
Abstract
This study aimed to assess the prevalence of seven periodontal marker pathogens, before implant placement and 1 yr after loading, in periodontally healthy individuals and to assess the long-term effectiveness of pre-implant reduction of pathogens to below threshold levels. In 93 individuals needing single tooth replacement, pooled subgingival microbiological samples from standard sites were cultured and analyzed before implant treatment and 1 yr after loading. Threshold levels commonly used in periodontology to predict periodontal breakdown were applied. Subjects with levels of pathogens above these thresholds received initial periodontal treatment including systemic antibiotics when indicated. At baseline, 49.5% of periodontally healthy subjects harboured one or more marker pathogens above threshold levels. Periodontal treatment reduced the pathogen levels below threshold values in 78.3% of these initially colonized subjects. In all cases Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis were reduced to below threshold. At 1 yr after loading, periodontal pathogens were present above threshold levels in 74.1% of all subjects. It is concluded that in almost half of periodontal healthy individuals the subgingival biofilm harbours periodontal pathogens above threshold values. Long-term effectiveness of pre-implant reduction of the selected marker pathogens appeared limited in our patient population, making pre-implant reduction unpredictive for post-implant levels of these pathogens. Thus, considering the applied microbiological criteria, generalized pre-implant microbiological testing is not contributory in periodontally healthy subjects.
DOI: 10.1111/j.1600-0722.2010.00750.x
PubMed: 20662908
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Raghoebar</name></author><author><name sortKey="Meijer, Henny J A" sort="Meijer, Henny J A" uniqKey="Meijer H" first="Henny J A" last="Meijer">Henny J A. Meijer</name></author><author><name sortKey="Vissink, Arjan" sort="Vissink, Arjan" uniqKey="Vissink A" first="Arjan" last="Vissink">Arjan Vissink</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="RBID">pubmed:20662908</idno><idno type="pmid">20662908</idno><idno type="doi">10.1111/j.1600-0722.2010.00750.x</idno><idno type="wicri:Area/PubMed/Corpus">001874</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001874</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Microbiota around teeth and dental implants in periodontally healthy, partially edentulous patients: is pre-implant microbiological testing relevant?</title><author><name sortKey="Meijndert, Leo" sort="Meijndert, Leo" uniqKey="Meijndert L" first="Leo" last="Meijndert">Leo Meijndert</name><affiliation><nlm:affiliation>Department of Oral and Maxillofacial Surgery and Maxillofacial Prosthetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. l.meijndert@planet.nl</nlm:affiliation></affiliation></author><author><name sortKey="Van Der Reijden, Wil A" sort="Van Der Reijden, Wil A" uniqKey="Van Der Reijden W" first="Wil A" last="Van Der Reijden">Wil A. Van Der Reijden</name></author><author><name sortKey="Raghoebar, Gerry M" sort="Raghoebar, Gerry M" uniqKey="Raghoebar G" first="Gerry M" last="Raghoebar">Gerry M. Raghoebar</name></author><author><name sortKey="Meijer, Henny J A" sort="Meijer, Henny J A" uniqKey="Meijer H" first="Henny J A" last="Meijer">Henny J A. Meijer</name></author><author><name sortKey="Vissink, Arjan" sort="Vissink, Arjan" uniqKey="Vissink A" first="Arjan" last="Vissink">Arjan Vissink</name></author></analytic><series><title level="j">European journal of oral sciences</title><idno type="eISSN">1600-0722</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aggregatibacter actinomycetemcomitans (isolation & purification)</term><term>Anti-Bacterial Agents (therapeutic use)</term><term>Bacterial Load</term><term>Bacteroides (isolation & purification)</term><term>Biofilms</term><term>Campylobacter rectus (isolation & purification)</term><term>Dental Implants, Single-Tooth (microbiology)</term><term>Dental Plaque (microbiology)</term><term>Female</term><term>Follow-Up Studies</term><term>Fusobacterium nucleatum (isolation & purification)</term><term>Gram-Negative Bacteria (classification)</term><term>Humans</term><term>Jaw, Edentulous, Partially (microbiology)</term><term>Jaw, Edentulous, Partially (rehabilitation)</term><term>Male</term><term>Maxilla (surgery)</term><term>Middle Aged</term><term>Patient Care Planning</term><term>Peptostreptococcus (isolation & purification)</term><term>Periodontal Pocket (microbiology)</term><term>Periodontium (microbiology)</term><term>Porphyromonas gingivalis (isolation & purification)</term><term>Preoperative Care</term><term>Prevotella intermedia (isolation & purification)</term><term>Tooth (microbiology)</term><term>Young Adult</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Bacterial Agents</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Gram-Negative Bacteria</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Aggregatibacter actinomycetemcomitans</term><term>Bacteroides</term><term>Campylobacter rectus</term><term>Fusobacterium nucleatum</term><term>Peptostreptococcus</term><term>Porphyromonas gingivalis</term><term>Prevotella intermedia</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Dental Implants, Single-Tooth</term><term>Dental Plaque</term><term>Jaw, Edentulous, Partially</term><term>Periodontal Pocket</term><term>Periodontium</term><term>Tooth</term></keywords><keywords scheme="MESH" qualifier="rehabilitation" xml:lang="en"><term>Jaw, Edentulous, Partially</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Maxilla</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Bacterial Load</term><term>Biofilms</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Patient Care Planning</term><term>Preoperative Care</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This study aimed to assess the prevalence of seven periodontal marker pathogens, before implant placement and 1 yr after loading, in periodontally healthy individuals and to assess the long-term effectiveness of pre-implant reduction of pathogens to below threshold levels. In 93 individuals needing single tooth replacement, pooled subgingival microbiological samples from standard sites were cultured and analyzed before implant treatment and 1 yr after loading. Threshold levels commonly used in periodontology to predict periodontal breakdown were applied. Subjects with levels of pathogens above these thresholds received initial periodontal treatment including systemic antibiotics when indicated. At baseline, 49.5% of periodontally healthy subjects harboured one or more marker pathogens above threshold levels. Periodontal treatment reduced the pathogen levels below threshold values in 78.3% of these initially colonized subjects. In all cases Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis were reduced to below threshold. At 1 yr after loading, periodontal pathogens were present above threshold levels in 74.1% of all subjects. It is concluded that in almost half of periodontal healthy individuals the subgingival biofilm harbours periodontal pathogens above threshold values. Long-term effectiveness of pre-implant reduction of the selected marker pathogens appeared limited in our patient population, making pre-implant reduction unpredictive for post-implant levels of these pathogens. Thus, considering the applied microbiological criteria, generalized pre-implant microbiological testing is not contributory in periodontally healthy subjects.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">20662908</PMID><DateCompleted><Year>2010</Year><Month>12</Month><Day>08</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1600-0722</ISSN><JournalIssue CitedMedium="Internet"><Volume>118</Volume><Issue>4</Issue><PubDate><Year>2010</Year><Month>Aug</Month></PubDate></JournalIssue><Title>European journal of oral sciences</Title><ISOAbbreviation>Eur. J. Oral Sci.</ISOAbbreviation></Journal><ArticleTitle>Microbiota around teeth and dental implants in periodontally healthy, partially edentulous patients: is pre-implant microbiological testing relevant?</ArticleTitle><Pagination><MedlinePgn>357-63</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/j.1600-0722.2010.00750.x</ELocationID><Abstract><AbstractText>This study aimed to assess the prevalence of seven periodontal marker pathogens, before implant placement and 1 yr after loading, in periodontally healthy individuals and to assess the long-term effectiveness of pre-implant reduction of pathogens to below threshold levels. In 93 individuals needing single tooth replacement, pooled subgingival microbiological samples from standard sites were cultured and analyzed before implant treatment and 1 yr after loading. Threshold levels commonly used in periodontology to predict periodontal breakdown were applied. Subjects with levels of pathogens above these thresholds received initial periodontal treatment including systemic antibiotics when indicated. At baseline, 49.5% of periodontally healthy subjects harboured one or more marker pathogens above threshold levels. Periodontal treatment reduced the pathogen levels below threshold values in 78.3% of these initially colonized subjects. In all cases Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis were reduced to below threshold. At 1 yr after loading, periodontal pathogens were present above threshold levels in 74.1% of all subjects. It is concluded that in almost half of periodontal healthy individuals the subgingival biofilm harbours periodontal pathogens above threshold values. Long-term effectiveness of pre-implant reduction of the selected marker pathogens appeared limited in our patient population, making pre-implant reduction unpredictive for post-implant levels of these pathogens. Thus, considering the applied microbiological criteria, generalized pre-implant microbiological testing is not contributory in periodontally healthy subjects.</AbstractText><CopyrightInformation>(c) 2010 The Authors. Journal compilation (c) 2010 Eur J Oral Sci.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Meijndert</LastName><ForeName>Leo</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Oral and Maxillofacial Surgery and Maxillofacial Prosthetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. l.meijndert@planet.nl</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Reijden</LastName><ForeName>Wil A</ForeName><Initials>WA</Initials></Author><Author ValidYN="Y"><LastName>Raghoebar</LastName><ForeName>Gerry M</ForeName><Initials>GM</Initials></Author><Author ValidYN="Y"><LastName>Meijer</LastName><ForeName>Henny J A</ForeName><Initials>HJ</Initials></Author><Author ValidYN="Y"><LastName>Vissink</LastName><ForeName>Arjan</ForeName><Initials>A</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Eur J Oral Sci</MedlineTA><NlmUniqueID>9504563</NlmUniqueID><ISSNLinking>0909-8836</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000900">Anti-Bacterial Agents</NameOfSubstance></Chemical></ChemicalList><CitationSubset>D</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016976" MajorTopicYN="N">Aggregatibacter actinomycetemcomitans</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000900" MajorTopicYN="N">Anti-Bacterial Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D058491" MajorTopicYN="N">Bacterial Load</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001439" MajorTopicYN="N">Bacteroides</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018441" MajorTopicYN="N">Biofilms</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D044883" MajorTopicYN="N">Campylobacter rectus</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019250" MajorTopicYN="N">Dental Implants, Single-Tooth</DescriptorName><QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003773" MajorTopicYN="N">Dental Plaque</DescriptorName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016967" MajorTopicYN="N">Fusobacterium nucleatum</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006090" MajorTopicYN="N">Gram-Negative Bacteria</DescriptorName><QualifierName UI="Q000145" MajorTopicYN="Y">classification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007576" MajorTopicYN="N">Jaw, Edentulous, Partially</DescriptorName><QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName><QualifierName UI="Q000534" MajorTopicYN="N">rehabilitation</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008437" MajorTopicYN="N">Maxilla</DescriptorName><QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010347" MajorTopicYN="Y">Patient Care Planning</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010462" MajorTopicYN="N">Peptostreptococcus</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010514" MajorTopicYN="N">Periodontal Pocket</DescriptorName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010519" MajorTopicYN="N">Periodontium</DescriptorName><QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016966" MajorTopicYN="N">Porphyromonas gingivalis</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011300" MajorTopicYN="N">Preoperative Care</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018713" MajorTopicYN="N">Prevotella intermedia</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014070" MajorTopicYN="N">Tooth</DescriptorName><QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2010</Year><Month>7</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2010</Year><Month>7</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2010</Year><Month>12</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">20662908</ArticleId><ArticleId IdType="pii">EOS750</ArticleId><ArticleId IdType="doi">10.1111/j.1600-0722.2010.00750.x</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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