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Guided bone regeneration using cyanoacrylate-combined calcium phosphate in a dehiscence defect: a histologic study in dogs.

Identifieur interne : 000F73 ( PubMed/Corpus ); précédent : 000F72; suivant : 000F74

Guided bone regeneration using cyanoacrylate-combined calcium phosphate in a dehiscence defect: a histologic study in dogs.

Auteurs : Jung-Seok Lee ; Seung-Hee Ko ; Young-Taek Kim ; Ui-Won Jung ; Seong-Ho Choi

Source :

RBID : pubmed:22749520

English descriptors

Abstract

This study evaluated the effects of cyanoacrylate-combined calcium phosphate (CCP) as a candidate for a barrier membrane substitute in guided bone regeneration and the space maintenance capability of CCP placed in a dehiscence defect model.

DOI: 10.1016/j.joms.2012.04.044
PubMed: 22749520

Links to Exploration step

pubmed:22749520

Le document en format XML

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<title xml:lang="en">Guided bone regeneration using cyanoacrylate-combined calcium phosphate in a dehiscence defect: a histologic study in dogs.</title>
<author>
<name sortKey="Lee, Jung Seok" sort="Lee, Jung Seok" uniqKey="Lee J" first="Jung-Seok" last="Lee">Jung-Seok Lee</name>
<affiliation>
<nlm:affiliation>Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University, Seoul, Korea.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Ko, Seung Hee" sort="Ko, Seung Hee" uniqKey="Ko S" first="Seung-Hee" last="Ko">Seung-Hee Ko</name>
</author>
<author>
<name sortKey="Kim, Young Taek" sort="Kim, Young Taek" uniqKey="Kim Y" first="Young-Taek" last="Kim">Young-Taek Kim</name>
</author>
<author>
<name sortKey="Jung, Ui Won" sort="Jung, Ui Won" uniqKey="Jung U" first="Ui-Won" last="Jung">Ui-Won Jung</name>
</author>
<author>
<name sortKey="Choi, Seong Ho" sort="Choi, Seong Ho" uniqKey="Choi S" first="Seong-Ho" last="Choi">Seong-Ho Choi</name>
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<title xml:lang="en">Guided bone regeneration using cyanoacrylate-combined calcium phosphate in a dehiscence defect: a histologic study in dogs.</title>
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<name sortKey="Lee, Jung Seok" sort="Lee, Jung Seok" uniqKey="Lee J" first="Jung-Seok" last="Lee">Jung-Seok Lee</name>
<affiliation>
<nlm:affiliation>Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University, Seoul, Korea.</nlm:affiliation>
</affiliation>
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<author>
<name sortKey="Ko, Seung Hee" sort="Ko, Seung Hee" uniqKey="Ko S" first="Seung-Hee" last="Ko">Seung-Hee Ko</name>
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<name sortKey="Kim, Young Taek" sort="Kim, Young Taek" uniqKey="Kim Y" first="Young-Taek" last="Kim">Young-Taek Kim</name>
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<name sortKey="Jung, Ui Won" sort="Jung, Ui Won" uniqKey="Jung U" first="Ui-Won" last="Jung">Ui-Won Jung</name>
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<name sortKey="Choi, Seong Ho" sort="Choi, Seong Ho" uniqKey="Choi S" first="Seong-Ho" last="Choi">Seong-Ho Choi</name>
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<series>
<title level="j">Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons</title>
<idno type="eISSN">1531-5053</idno>
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<date when="2012" type="published">2012</date>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Alveolar Bone Loss (pathology)</term>
<term>Alveolar Bone Loss (surgery)</term>
<term>Animals</term>
<term>Biocompatible Materials (chemistry)</term>
<term>Bone Regeneration (physiology)</term>
<term>Bone Substitutes (therapeutic use)</term>
<term>Calcium Phosphates (chemistry)</term>
<term>Cyanoacrylates (chemistry)</term>
<term>Dental Implants</term>
<term>Disease Models, Animal</term>
<term>Dogs</term>
<term>Guided Tissue Regeneration, Periodontal (methods)</term>
<term>Hydroxyapatites (therapeutic use)</term>
<term>Jaw, Edentulous (pathology)</term>
<term>Jaw, Edentulous (surgery)</term>
<term>Male</term>
<term>Mandible (pathology)</term>
<term>Mandible (surgery)</term>
<term>Membranes, Artificial</term>
<term>Osseointegration (physiology)</term>
<term>Osteogenesis (physiology)</term>
<term>Polytetrafluoroethylene</term>
<term>Tissue Scaffolds</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en">
<term>Biocompatible Materials</term>
<term>Calcium Phosphates</term>
<term>Cyanoacrylates</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Guided Tissue Regeneration, Periodontal</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Alveolar Bone Loss</term>
<term>Jaw, Edentulous</term>
<term>Mandible</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en">
<term>Bone Regeneration</term>
<term>Osseointegration</term>
<term>Osteogenesis</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Alveolar Bone Loss</term>
<term>Jaw, Edentulous</term>
<term>Mandible</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en">
<term>Bone Substitutes</term>
<term>Hydroxyapatites</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Animals</term>
<term>Dental Implants</term>
<term>Disease Models, Animal</term>
<term>Dogs</term>
<term>Male</term>
<term>Membranes, Artificial</term>
<term>Polytetrafluoroethylene</term>
<term>Tissue Scaffolds</term>
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<front>
<div type="abstract" xml:lang="en">This study evaluated the effects of cyanoacrylate-combined calcium phosphate (CCP) as a candidate for a barrier membrane substitute in guided bone regeneration and the space maintenance capability of CCP placed in a dehiscence defect model.</div>
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<PMID Version="1">22749520</PMID>
<DateCompleted>
<Year>2012</Year>
<Month>11</Month>
<Day>30</Day>
</DateCompleted>
<DateRevised>
<Year>2013</Year>
<Month>04</Month>
<Day>05</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1531-5053</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>70</Volume>
<Issue>9</Issue>
<PubDate>
<Year>2012</Year>
<Month>Sep</Month>
</PubDate>
</JournalIssue>
<Title>Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons</Title>
<ISOAbbreviation>J. Oral Maxillofac. Surg.</ISOAbbreviation>
</Journal>
<ArticleTitle>Guided bone regeneration using cyanoacrylate-combined calcium phosphate in a dehiscence defect: a histologic study in dogs.</ArticleTitle>
<Pagination>
<MedlinePgn>2070-9</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.joms.2012.04.044</ELocationID>
<Abstract>
<AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">This study evaluated the effects of cyanoacrylate-combined calcium phosphate (CCP) as a candidate for a barrier membrane substitute in guided bone regeneration and the space maintenance capability of CCP placed in a dehiscence defect model.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">Six standardized dehiscence defects (5 × 3 mm, height × width) around dental implants were created on unilateral edentulous ridges in 5 dogs, where each defect was treated with sham surgery, biphasic calcium phosphate (BCP), CCP, barrier membrane (MEM), BCP + MEM, and CCP + MEM. The animals were sacrificed after an 8-week healing interval for histologic and histometric analyses.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The BCP and CCP sites showed increased bone formation compared with the control sites, although incomplete defect resolution occurred; bone regeneration heights (area) averaged 3.52 ± 0.69 mm (4.94 ± 2.59 mm(2)), 3.51 ± 0.16 mm (4.10 ± 1.99 mm(2)), and 1.53 ± 0.42 mm (1.01 ± 0.74 mm(2)) for the BCP, CCP, and control sites, respectively. All the MEM sites showed more bone formation compared with the sites that received the same biomaterials without a MEM, and the BCP + MEM and CCP + MEM sites showed extensive bone formation within the defect and on top of the implant; the bone regeneration heights (area) averaged 3.96 ± 2.86 mm (12.46 ± 11.61 mm(2)), 5.45 ± 0.25 mm (11.63 ± 1.97 mm(2)), and 2.62 ± 0.27 mm (3.43 ± 0.98 mm(2)) for the BCP + MEM, CCP + MEM, and MEM sites, respectively.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">CCP can be a good scaffold for supporting an MEM as opposed to acting as a substitute for the MEM in guided bone regeneration.</AbstractText>
<CopyrightInformation>Copyright © 2012 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.</CopyrightInformation>
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<LastName>Lee</LastName>
<ForeName>Jung-Seok</ForeName>
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<Affiliation>Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University, Seoul, Korea.</Affiliation>
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<Language>eng</Language>
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<Country>United States</Country>
<MedlineTA>J Oral Maxillofac Surg</MedlineTA>
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<NameOfSubstance UI="D002130">Calcium Phosphates</NameOfSubstance>
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<NameOfSubstance UI="D003487">Cyanoacrylates</NameOfSubstance>
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</Chemical>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D008567">Membranes, Artificial</NameOfSubstance>
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<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C074950">hydroxyapatite-beta tricalcium phosphate</NameOfSubstance>
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<Chemical>
<RegistryNumber>9002-84-0</RegistryNumber>
<NameOfSubstance UI="D011138">Polytetrafluoroethylene</NameOfSubstance>
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<RegistryNumber>97Z1WI3NDX</RegistryNumber>
<NameOfSubstance UI="C020243">calcium phosphate</NameOfSubstance>
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<DescriptorName UI="D016301" MajorTopicYN="N">Alveolar Bone Loss</DescriptorName>
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<DescriptorName UI="D008334" MajorTopicYN="N">Mandible</DescriptorName>
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<DescriptorName UI="D008567" MajorTopicYN="N">Membranes, Artificial</DescriptorName>
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