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Minor physical anomalies in schizophrenia: is age a confounding factor?

Identifieur interne : 002643 ( PubMed/Checkpoint ); précédent : 002642; suivant : 002644

Minor physical anomalies in schizophrenia: is age a confounding factor?

Auteurs : Tuhina Lloyd [Royaume-Uni] ; Gillian Doody ; John Brewin ; Bert Park ; Peter Jones

Source :

Schizophrenia research [ 0920-9964 ] ; 2003.

RBID : pubmed:12648737

Descripteurs français

KwdFr :
- Adulte d'âge moyen, Anthropométrie, Bouche édentée, Facteurs de l'âge, Femelle, Humains, Mâle, Oeil (anatomie et histologie), Oreille (anatomie et histologie), Palais (anatomie et histologie), Poils (physiologie), Reproductibilité des résultats, Schizophrénie (), Sujet âgé, Sujet âgé de 80 ans ou plus.
MESH :
- anatomie et histologie : Oeil, Oreille, Palais.
- physiologie : Poils.
- Adulte d'âge moyen, Anthropométrie, Bouche édentée, Facteurs de l'âge, Femelle, Humains, Mâle, Reproductibilité des résultats, Schizophrénie, Sujet âgé, Sujet âgé de 80 ans ou plus.

English descriptors

KwdEn :
- Age Factors, Aged, Aged, 80 and over, Anthropometry, Ear (anatomy & histology), Eye (anatomy & histology), Female, Hair (physiology), Humans, Male, Middle Aged, Mouth, Edentulous, Palate (anatomy & histology), Reproducibility of Results, Schizophrenia (complications).
MESH :
- anatomy & histology : Ear, Eye, Palate.
- complications : Schizophrenia.
- physiology : Hair.
- Age Factors, Aged, Aged, 80 and over, Anthropometry, Female, Humans, Male, Middle Aged, Mouth, Edentulous, Reproducibility of Results.

Abstract

Minor physical anomalies (MPAs) occur more frequently in a range of developmental disorders. They are also more frequent in schizophrenia supporting a neurodevelopmental aetiology of the illness. Contemporary MPA scales are yet to be validated for the effects of age. It is hypothesised that the effects of ageing may be confounding when these scales are applied to an elderly population. The distribution of MPAs in a normal elderly population was compared with younger subjects. Fifty subjects over the age of 60, and 50 subjects below the age of 60, with no known major mental illness, were evaluated. MPAs were assessed using a modified Lane scale [Psychol. Med. 27 (1997) 1155]. Elderly subjects showed an excess of absent trichions due to alopecia (p=0.004) short and broad palates (p=0.01) and greater ear protrusion (p=0.004) relative to young subjects. The differences reported are probably due to hair loss, edentulousness and growth of the auriculocephalic angle with age. These findings question the validity of studies of MPAs in schizophrenia that do not control for age.

PubMed: 12648737

Affiliations:

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pubmed:12648737

Le document en format XML

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<term>Humans</term>
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<term>Schizophrénie ()</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
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<term>Humans</term>
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<term>Middle Aged</term>
<term>Mouth, Edentulous</term>
<term>Reproducibility of Results</term>
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<term>Bouche édentée</term>
<term>Facteurs de l'âge</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Reproductibilité des résultats</term>
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<term>Sujet âgé</term>
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<front><div type="abstract" xml:lang="en">Minor physical anomalies (MPAs) occur more frequently in a range of developmental disorders. They are also more frequent in schizophrenia supporting a neurodevelopmental aetiology of the illness. Contemporary MPA scales are yet to be validated for the effects of age. It is hypothesised that the effects of ageing may be confounding when these scales are applied to an elderly population. The distribution of MPAs in a normal elderly population was compared with younger subjects. Fifty subjects over the age of 60, and 50 subjects below the age of 60, with no known major mental illness, were evaluated. MPAs were assessed using a modified Lane scale [Psychol. Med. 27 (1997) 1155]. Elderly subjects showed an excess of absent trichions due to alopecia (p=0.004) short and broad palates (p=0.01) and greater ear protrusion (p=0.004) relative to young subjects. The differences reported are probably due to hair loss, edentulousness and growth of the auriculocephalic angle with age. These findings question the validity of studies of MPAs in schizophrenia that do not control for age.</div>
</front>
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<Abstract><AbstractText>Minor physical anomalies (MPAs) occur more frequently in a range of developmental disorders. They are also more frequent in schizophrenia supporting a neurodevelopmental aetiology of the illness. Contemporary MPA scales are yet to be validated for the effects of age. It is hypothesised that the effects of ageing may be confounding when these scales are applied to an elderly population. The distribution of MPAs in a normal elderly population was compared with younger subjects. Fifty subjects over the age of 60, and 50 subjects below the age of 60, with no known major mental illness, were evaluated. MPAs were assessed using a modified Lane scale [Psychol. Med. 27 (1997) 1155]. Elderly subjects showed an excess of absent trichions due to alopecia (p=0.004) short and broad palates (p=0.01) and greater ear protrusion (p=0.004) relative to young subjects. The differences reported are probably due to hair loss, edentulousness and growth of the auriculocephalic angle with age. These findings question the validity of studies of MPAs in schizophrenia that do not control for age.</AbstractText>
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Minor physical anomalies in schizophrenia: is age a confounding factor?

Minor physical anomalies in schizophrenia: is age a confounding factor?

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki