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Total tooth loss and prevalent cardiovascular disease in men and women: possible roles of citrus fruit consumption, vitamin C, and inflammatory and thrombotic variables.

Identifieur interne : 002569 ( PubMed/Checkpoint ); précédent : 002568; suivant : 002570

Total tooth loss and prevalent cardiovascular disease in men and women: possible roles of citrus fruit consumption, vitamin C, and inflammatory and thrombotic variables.

Auteurs : Gordon Lowe [Royaume-Uni] ; Mark Woodward ; Ann Rumley ; Caroline Morrison ; Hugh Tunstall-Pedoe ; Kenneth Stephen

Source :

RBID : pubmed:12921939

Descripteurs français

English descriptors

Abstract

Tooth loss has been associated with cardiovascular disease (CVD), but the mechanisms are unclear. We evaluated the association of total tooth loss with prevalent CVD in men and women; as well as with citrus fruit consumption, plasma vitamin C, and inflammatory and thrombotic variables.

PubMed: 12921939


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pubmed:12921939

Le document en format XML

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<name sortKey="Lowe, Gordon" sort="Lowe, Gordon" uniqKey="Lowe G" first="Gordon" last="Lowe">Gordon Lowe</name>
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<nlm:affiliation>University Department of Medicine, Royal Infirmary, 10 Alexandra Parade, Glasgow, G31 2ER, UK. gdl1j@clinmed.gla.ac.uk</nlm:affiliation>
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<name sortKey="Morrison, Caroline" sort="Morrison, Caroline" uniqKey="Morrison C" first="Caroline" last="Morrison">Caroline Morrison</name>
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<name sortKey="Tunstall Pedoe, Hugh" sort="Tunstall Pedoe, Hugh" uniqKey="Tunstall Pedoe H" first="Hugh" last="Tunstall-Pedoe">Hugh Tunstall-Pedoe</name>
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<front>
<div type="abstract" xml:lang="en">Tooth loss has been associated with cardiovascular disease (CVD), but the mechanisms are unclear. We evaluated the association of total tooth loss with prevalent CVD in men and women; as well as with citrus fruit consumption, plasma vitamin C, and inflammatory and thrombotic variables.</div>
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<DateCompleted>
<Year>2003</Year>
<Month>10</Month>
<Day>16</Day>
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<DateRevised>
<Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
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<Volume>56</Volume>
<Issue>7</Issue>
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<Title>Journal of clinical epidemiology</Title>
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<AbstractText Label="BACKGROUND AND OBJECTIVE" NlmCategory="OBJECTIVE">Tooth loss has been associated with cardiovascular disease (CVD), but the mechanisms are unclear. We evaluated the association of total tooth loss with prevalent CVD in men and women; as well as with citrus fruit consumption, plasma vitamin C, and inflammatory and thrombotic variables.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We used an age-and sex-stratified population survey, of men and women aged 25-74 years, in North Glasgow.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Thirty-eight percent of women and 29% of men were edentulous. Total tooth loss was associated with prevalent CVD in both sexes. After adjustment for major potential confounders (age, sex, smoking, and social class), the odds ratio (95% CI) for prevalent CVD was 1.55 (1.13, 2.13) in the edentulous. Total tooth loss was also associated with low citrus fruit consumption and low plasma vitamin C levels, increased plasma C-reactive protein in men, and with increased plasma interleukin-6, fibrinogen, and factor VIII levels in women.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Prevalent CVD is associated with total tooth loss. Possible mechanisms include low intake of citrus fruit, and hence, low plasma vitamin C levels, and a predisposition to low-grade inflammation and thrombosis. It may be prudent to ensure adequate vitamin C intake in people with no teeth.</AbstractText>
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