Interleukin-1β level in peri-implant crevicular fluid and its correlation with the clinical and radiographic parameters
Identifieur interne : 003176 ( Pmc/Curation ); précédent : 003175; suivant : 003177Interleukin-1β level in peri-implant crevicular fluid and its correlation with the clinical and radiographic parameters
Auteurs : Aniruddha M. Kajale ; Dhoom S. MehtaSource :
- Journal of Indian Society of Periodontology [ 0972-124X ] ; 2014.
Abstract
Assessing only the clinical and radiographic parameters for evaluation of dental implants may not be enough as they often reflect extensive inflammatory changes in the periodontal tissues. As peri-implant crevicular fluid (PICF) can give us a more prompt and objective measure of the disease activity, the purpose of this case series is to assess the peri-implant health status of single tooth dental implants not only clinically and radiographically but also biochemically.
Thirteen patients were subjected to dental implants at single edentulous sites using a conventional surgical approach. At baseline, 6 months, and 12 months after implant placement, the clinical and radiographic parameters were recorded. Additionally, IL-1β in PICF was estimated using the ELISA kit at 6th and 12th month.
The clinical and radiographic parameters differed significantly around the implants at different time intervals with IL-1β levels showing highly significant differences between 6 months (31.79 ± 12.26 pg/μl) and 12 months (113.09 ± 51.11 pg/μl). However, Spearman's correlation coefficient showed no correlation with the clinical and radiographic parameters.
Assessment of the various parameters confirmed that all the implants had a healthy peri-implant status. Although the levels of IL-1β in PICF were elevated at the 12th month, they were well within the healthy range as observed by previous studies. This indicates that IL-1β, a biochemical marker, can be used as an adjunct to clinical and radiographic parameters in the assessment of EARLY inflammatory changes around implants.
Url:
DOI: 10.4103/0972-124X.131331
PubMed: 24872632
PubMed Central: 4033890
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<author><name sortKey="Kajale, Aniruddha M" sort="Kajale, Aniruddha M" uniqKey="Kajale A" first="Aniruddha M." last="Kajale">Aniruddha M. Kajale</name>
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<author><name sortKey="Mehta, Dhoom S" sort="Mehta, Dhoom S" uniqKey="Mehta D" first="Dhoom S." last="Mehta">Dhoom S. Mehta</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Interleukin-1β level in peri-implant crevicular fluid and its correlation with the clinical and radiographic parameters</title>
<author><name sortKey="Kajale, Aniruddha M" sort="Kajale, Aniruddha M" uniqKey="Kajale A" first="Aniruddha M." last="Kajale">Aniruddha M. Kajale</name>
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<front><div type="abstract" xml:lang="en"><sec id="st1"><title>Background and Objectives:</title>
<p>Assessing only the clinical and radiographic parameters for evaluation of dental implants may not be enough as they often reflect extensive inflammatory changes in the periodontal tissues. As peri-implant crevicular fluid (PICF) can give us a more prompt and objective measure of the disease activity, the purpose of this case series is to assess the peri-implant health status of single tooth dental implants not only clinically and radiographically but also biochemically.</p>
</sec>
<sec id="st2"><title>Materials and Methods:</title>
<p>Thirteen patients were subjected to dental implants at single edentulous sites using a conventional surgical approach. At baseline, 6 months, and 12 months after implant placement, the clinical and radiographic parameters were recorded. Additionally, IL-1β in PICF was estimated using the ELISA kit at 6<sup>th</sup>
and 12<sup>th</sup>
month.</p>
</sec>
<sec id="st3"><title>Results:</title>
<p>The clinical and radiographic parameters differed significantly around the implants at different time intervals with IL-1β levels showing highly significant differences between 6 months (31.79 ± 12.26 pg/μl) and 12 months (113.09 ± 51.11 pg/μl). However, Spearman's correlation coefficient showed no correlation with the clinical and radiographic parameters.</p>
</sec>
<sec id="st4"><title>Interpretation and Conclusion:</title>
<p>Assessment of the various parameters confirmed that all the implants had a healthy peri-implant status. Although the levels of IL-1β in PICF were elevated at the 12<sup>th</sup>
month, they were well within the healthy range as observed by previous studies. This indicates that IL-1β, a biochemical marker, can be used as an adjunct to clinical and radiographic parameters in the assessment of EARLY inflammatory changes around implants.</p>
</sec>
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<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Indian Soc Periodontol</journal-id>
<journal-id journal-id-type="iso-abbrev">J Indian Soc Periodontol</journal-id>
<journal-id journal-id-type="publisher-id">JISP</journal-id>
<journal-title-group><journal-title>Journal of Indian Society of Periodontology</journal-title>
</journal-title-group>
<issn pub-type="ppub">0972-124X</issn>
<issn pub-type="epub">0975-1580</issn>
<publisher><publisher-name>Medknow Publications & Media Pvt Ltd</publisher-name>
<publisher-loc>India</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">24872632</article-id>
<article-id pub-id-type="pmc">4033890</article-id>
<article-id pub-id-type="publisher-id">JISP-18-220</article-id>
<article-id pub-id-type="doi">10.4103/0972-124X.131331</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Interleukin-1β level in peri-implant crevicular fluid and its correlation with the clinical and radiographic parameters</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Kajale</surname>
<given-names>Aniruddha M.</given-names>
</name>
<xref ref-type="aff" rid="aff1"></xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mehta</surname>
<given-names>Dhoom S.</given-names>
</name>
<xref ref-type="aff" rid="aff1"></xref>
<xref ref-type="corresp" rid="cor1"></xref>
</contrib>
</contrib-group>
<aff id="aff1"><italic>Department of Periodontics, Bapuji Dental College and Hospital, Davangere, Karnataka, India</italic>
</aff>
<author-notes><corresp id="cor1"><bold>Address for correspondence:</bold>
Dr. Dhoom S. Mehta, Department of Periodontics, Bapuji Dental College and Hospital, Davangere - 577 004, Karnataka, India. E-mail: <email xlink:href="dsmehta2010@gmail.com">dsmehta2010@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><season>Mar-Apr</season>
<year>2014</year>
</pub-date>
<volume>18</volume>
<issue>2</issue>
<fpage>220</fpage>
<lpage>225</lpage>
<history><date date-type="received"><day>22</day>
<month>3</month>
<year>2012</year>
</date>
<date date-type="accepted"><day>04</day>
<month>10</month>
<year>2013</year>
</date>
</history>
<permissions><copyright-statement>Copyright: © Journal of Indian Society of Periodontology</copyright-statement>
<copyright-year>2014</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract><sec id="st1"><title>Background and Objectives:</title>
<p>Assessing only the clinical and radiographic parameters for evaluation of dental implants may not be enough as they often reflect extensive inflammatory changes in the periodontal tissues. As peri-implant crevicular fluid (PICF) can give us a more prompt and objective measure of the disease activity, the purpose of this case series is to assess the peri-implant health status of single tooth dental implants not only clinically and radiographically but also biochemically.</p>
</sec>
<sec id="st2"><title>Materials and Methods:</title>
<p>Thirteen patients were subjected to dental implants at single edentulous sites using a conventional surgical approach. At baseline, 6 months, and 12 months after implant placement, the clinical and radiographic parameters were recorded. Additionally, IL-1β in PICF was estimated using the ELISA kit at 6<sup>th</sup>
and 12<sup>th</sup>
month.</p>
</sec>
<sec id="st3"><title>Results:</title>
<p>The clinical and radiographic parameters differed significantly around the implants at different time intervals with IL-1β levels showing highly significant differences between 6 months (31.79 ± 12.26 pg/μl) and 12 months (113.09 ± 51.11 pg/μl). However, Spearman's correlation coefficient showed no correlation with the clinical and radiographic parameters.</p>
</sec>
<sec id="st4"><title>Interpretation and Conclusion:</title>
<p>Assessment of the various parameters confirmed that all the implants had a healthy peri-implant status. Although the levels of IL-1β in PICF were elevated at the 12<sup>th</sup>
month, they were well within the healthy range as observed by previous studies. This indicates that IL-1β, a biochemical marker, can be used as an adjunct to clinical and radiographic parameters in the assessment of EARLY inflammatory changes around implants.</p>
</sec>
</abstract>
<kwd-group><kwd>Dental implant</kwd>
<kwd>interleukin-1β</kwd>
<kwd>peri-implant crevicular fluid</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
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