Fibronectin-Grafted Titanium Dental Implants: An In Vivo Study
Identifieur interne : 002917 ( Pmc/Curation ); précédent : 002916; suivant : 002918Fibronectin-Grafted Titanium Dental Implants: An In Vivo Study
Auteurs : Yu-Chi Chang [Taïwan] ; Kuo-Ning Ho [Taïwan] ; Sheng-Wei Feng [Taïwan] ; Haw-Ming Huang [Taïwan] ; Chia-Hsun Chang [Corée du Sud] ; Che-Tong Lin [Taïwan] ; Nai-Chia Teng [Taïwan] ; Yu Hwa Pan [Taïwan] ; Wei-Jen Chang [Taïwan]Source :
- BioMed Research International [ 2314-6133 ] ; 2016.
Abstract
Modification of the physiochemical properties of titanium surfaces using glow discharge plasma (GDP) and fibronectin coating has been shown to enhance the surface hydrophilicity, surface roughness, cell adhesion, migration, and proliferation. This
Url:
DOI: 10.1155/2016/2414809
PubMed: 27366739
PubMed Central: 4913050
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002917
Links to Exploration step
PMC:4913050Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Fibronectin-Grafted Titanium Dental Implants: An<italic> In Vivo</italic> Study</title><author><name sortKey="Chang, Yu Chi" sort="Chang, Yu Chi" uniqKey="Chang Y" first="Yu-Chi" last="Chang">Yu-Chi Chang</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation></author><author><name sortKey="Ho, Kuo Ning" sort="Ho, Kuo Ning" uniqKey="Ho K" first="Kuo-Ning" last="Ho">Kuo-Ning Ho</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation></author><author><name sortKey="Feng, Sheng Wei" sort="Feng, Sheng Wei" uniqKey="Feng S" first="Sheng-Wei" last="Feng">Sheng-Wei Feng</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation></author><author><name sortKey="Huang, Haw Ming" sort="Huang, Haw Ming" uniqKey="Huang H" first="Haw-Ming" last="Huang">Haw-Ming Huang</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="I2">Graduate Institute of Biomedical Materials & Tissue Engineering, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Graduate Institute of Biomedical Materials & Tissue Engineering, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation></author><author><name sortKey="Chang, Chia Hsun" sort="Chang, Chia Hsun" uniqKey="Chang C" first="Chia-Hsun" last="Chang">Chia-Hsun Chang</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of International Logistics, Chung-Ang University, Seoul 156756, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of International Logistics, Chung-Ang University, Seoul 156756</wicri:regionArea></affiliation></author><author><name sortKey="Lin, Che Tong" sort="Lin, Che Tong" uniqKey="Lin C" first="Che-Tong" last="Lin">Che-Tong Lin</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">Dental Department, Taipei Medical University Hospital, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Dental Department, Taipei Medical University Hospital, Taipei 110</wicri:regionArea></affiliation></author><author><name sortKey="Teng, Nai Chia" sort="Teng, Nai Chia" uniqKey="Teng N" first="Nai-Chia" last="Teng">Nai-Chia Teng</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">Dental Department, Taipei Medical University Hospital, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Dental Department, Taipei Medical University Hospital, Taipei 110</wicri:regionArea></affiliation></author><author><name sortKey="Pan, Yu Hwa" sort="Pan, Yu Hwa" uniqKey="Pan Y" first="Yu Hwa" last="Pan">Yu Hwa Pan</name><affiliation wicri:level="1"><nlm:aff id="I5">Department of General Dentistry, Chang Gung Memorial Hospital, Taipei 105, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of General Dentistry, Chang Gung Memorial Hospital, Taipei 105</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="I6">Graduate Institute of Dental & Craniofacial Science, Chang Gung University, Taoyuan 333, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Graduate Institute of Dental & Craniofacial Science, Chang Gung University, Taoyuan 333</wicri:regionArea></affiliation></author><author><name sortKey="Chang, Wei Jen" sort="Chang, Wei Jen" uniqKey="Chang W" first="Wei-Jen" last="Chang">Wei-Jen Chang</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="I7">Dental Department, Taipei Medical University, Shuang-Ho Hospital, Taipei 235, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Dental Department, Taipei Medical University, Shuang-Ho Hospital, Taipei 235</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27366739</idno><idno type="pmc">4913050</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913050</idno><idno type="RBID">PMC:4913050</idno><idno type="doi">10.1155/2016/2414809</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">002917</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002917</idno><idno type="wicri:Area/Pmc/Curation">002917</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002917</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Fibronectin-Grafted Titanium Dental Implants: An<italic> In Vivo</italic> Study</title><author><name sortKey="Chang, Yu Chi" sort="Chang, Yu Chi" uniqKey="Chang Y" first="Yu-Chi" last="Chang">Yu-Chi Chang</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation></author><author><name sortKey="Ho, Kuo Ning" sort="Ho, Kuo Ning" uniqKey="Ho K" first="Kuo-Ning" last="Ho">Kuo-Ning Ho</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation></author><author><name sortKey="Feng, Sheng Wei" sort="Feng, Sheng Wei" uniqKey="Feng S" first="Sheng-Wei" last="Feng">Sheng-Wei Feng</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation></author><author><name sortKey="Huang, Haw Ming" sort="Huang, Haw Ming" uniqKey="Huang H" first="Haw-Ming" last="Huang">Haw-Ming Huang</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="I2">Graduate Institute of Biomedical Materials & Tissue Engineering, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Graduate Institute of Biomedical Materials & Tissue Engineering, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation></author><author><name sortKey="Chang, Chia Hsun" sort="Chang, Chia Hsun" uniqKey="Chang C" first="Chia-Hsun" last="Chang">Chia-Hsun Chang</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of International Logistics, Chung-Ang University, Seoul 156756, Republic of Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of International Logistics, Chung-Ang University, Seoul 156756</wicri:regionArea></affiliation></author><author><name sortKey="Lin, Che Tong" sort="Lin, Che Tong" uniqKey="Lin C" first="Che-Tong" last="Lin">Che-Tong Lin</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">Dental Department, Taipei Medical University Hospital, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Dental Department, Taipei Medical University Hospital, Taipei 110</wicri:regionArea></affiliation></author><author><name sortKey="Teng, Nai Chia" sort="Teng, Nai Chia" uniqKey="Teng N" first="Nai-Chia" last="Teng">Nai-Chia Teng</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">Dental Department, Taipei Medical University Hospital, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Dental Department, Taipei Medical University Hospital, Taipei 110</wicri:regionArea></affiliation></author><author><name sortKey="Pan, Yu Hwa" sort="Pan, Yu Hwa" uniqKey="Pan Y" first="Yu Hwa" last="Pan">Yu Hwa Pan</name><affiliation wicri:level="1"><nlm:aff id="I5">Department of General Dentistry, Chang Gung Memorial Hospital, Taipei 105, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of General Dentistry, Chang Gung Memorial Hospital, Taipei 105</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="I6">Graduate Institute of Dental & Craniofacial Science, Chang Gung University, Taoyuan 333, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Graduate Institute of Dental & Craniofacial Science, Chang Gung University, Taoyuan 333</wicri:regionArea></affiliation></author><author><name sortKey="Chang, Wei Jen" sort="Chang, Wei Jen" uniqKey="Chang W" first="Wei-Jen" last="Chang">Wei-Jen Chang</name><affiliation wicri:level="1"><nlm:aff id="I1">School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="I7">Dental Department, Taipei Medical University, Shuang-Ho Hospital, Taipei 235, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Dental Department, Taipei Medical University, Shuang-Ho Hospital, Taipei 235</wicri:regionArea></affiliation></author></analytic><series><title level="j">BioMed Research International</title><idno type="ISSN">2314-6133</idno><idno type="eISSN">2314-6141</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Modification of the physiochemical properties of titanium surfaces using glow discharge plasma (GDP) and fibronectin coating has been shown to enhance the surface hydrophilicity, surface roughness, cell adhesion, migration, and proliferation. This<italic> in vivo</italic> study aimed to evaluate the bone integration efficacy of a biologically modified implant surface. Two different surface-modified implants (Ar-GDP and GDP-fib) were placed in the mandibular premolar area of six beagle dogs for 2–8 weeks. Three techniques [histologic evaluation, resonance frequency analysis (RFA), and microcomputed tomography (micro-CT) evaluation] were used to detect the implant stability and bone-implant contact. The implant stability quotient values of GDP-fib implants were significantly greater than the Ar-GDP implants at 2 and 4 weeks (<italic>P</italic> < 0.01). The bone volume/total volume ratio of GDP-fib implants was greater than the Ar-GDP implants in micro-CT evaluation. A high positive correlation was observed between RFA and micro-CT measurements. At 2 weeks, osteoblasts were seen to line the implant surface, and multinuclear osteoclasts could be seen on the surface of old parent bone. After 8 weeks, a majority of the space in the wound chamber appeared to be replaced by bone. Enhancement of the stability of biologically modified implants was proved by the results of RFA, micro-CT, and histological analysis. This enhanced stability may help fasten treatment and be clinically beneficial.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Branemark, P I" uniqKey="Branemark P">P.-I. Branemark</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shalabi, M M" uniqKey="Shalabi M">M. M. Shalabi</name></author><author><name sortKey="Wolke, J G" uniqKey="Wolke J">J. G. Wolke</name></author><author><name sortKey="Jansen, J A" uniqKey="Jansen J">J. A. Jansen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Blanco, J" uniqKey="Blanco J">J. Blanco</name></author><author><name sortKey="Alvarez, E" uniqKey="Alvarez E">E. Alvarez</name></author><author><name sortKey="Mu Oz, F" uniqKey="Mu Oz F">F. Muñoz</name></author><author><name sortKey="Li Ares, A" uniqKey="Li Ares A">A. Liñares</name></author><author><name sortKey="Cantalapiedra, A" uniqKey="Cantalapiedra A">A. Cantalapiedra</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rasmusson, L" uniqKey="Rasmusson L">L. Rasmusson</name></author><author><name sortKey="Meredith, N" uniqKey="Meredith N">N. Meredith</name></author><author><name sortKey="Cho, I H" uniqKey="Cho I">I. H. Cho</name></author><author><name sortKey="Sennerby, L" uniqKey="Sennerby L">L. Sennerby</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Glauser, R" uniqKey="Glauser R">R. Glauser</name></author><author><name sortKey="Sennerby, L" uniqKey="Sennerby L">L. Sennerby</name></author><author><name sortKey="Meredith, N" uniqKey="Meredith N">N. Meredith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Maeztu, M A" uniqKey="De Maeztu M">M. A. De Maeztu</name></author><author><name sortKey="Braceras, I" uniqKey="Braceras I">I. Braceras</name></author><author><name sortKey="Alava, J I" uniqKey="Alava J">J. I. Alava</name></author><author><name sortKey="Sanchez Garces, M A" uniqKey="Sanchez Garces M">M. A. Sánchez-Garcés</name></author><author><name sortKey="Gay Escoda, C" uniqKey="Gay Escoda C">C. Gay-Escoda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A. Wennerberg</name></author><author><name sortKey="Hallgren, C" uniqKey="Hallgren C">C. Hallgren</name></author><author><name sortKey="Johansson, C" uniqKey="Johansson C">C. Johansson</name></author><author><name sortKey="Danelli, S" uniqKey="Danelli S">S. Danelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lazzara, R J" uniqKey="Lazzara R">R. J. Lazzara</name></author><author><name sortKey="Testori, T" uniqKey="Testori T">T. Testori</name></author><author><name sortKey="Trisi, P" uniqKey="Trisi P">P. Trisi</name></author><author><name sortKey="Porter, S S" uniqKey="Porter S">S. S. Porter</name></author><author><name sortKey="Weinstein, R L" uniqKey="Weinstein R">R. L. Weinstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buser, D" uniqKey="Buser D">D. Buser</name></author><author><name sortKey="Schenk, R K" uniqKey="Schenk R">R. K. Schenk</name></author><author><name sortKey="Steinemann, S" uniqKey="Steinemann S">S. Steinemann</name></author><author><name sortKey="Fiorellini, J P" uniqKey="Fiorellini J">J. P. Fiorellini</name></author><author><name sortKey="Fox, C H" uniqKey="Fox C">C. H. Fox</name></author><author><name sortKey="Stich, H" uniqKey="Stich H">H. Stich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Choi, J W" uniqKey="Choi J">J. W. Choi</name></author><author><name sortKey="Heo, S J" uniqKey="Heo S">S. J. Heo</name></author><author><name sortKey="Koak, J Y" uniqKey="Koak J">J. Y. Koak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A. Wennerberg</name></author><author><name sortKey="Albrektsson, T" uniqKey="Albrektsson T">T. Albrektsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suvorova, E I" uniqKey="Suvorova E">E. I. Suvorova</name></author><author><name sortKey="Buffat, P A" uniqKey="Buffat P">P. A. Buffat</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shibata, Y" uniqKey="Shibata Y">Y. Shibata</name></author><author><name sortKey="Hosaka, M" uniqKey="Hosaka M">M. Hosaka</name></author><author><name sortKey="Kawai, H" uniqKey="Kawai H">H. Kawai</name></author><author><name sortKey="Miyazaki, T" uniqKey="Miyazaki T">T. Miyazaki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Placko, H E" uniqKey="Placko H">H. E. Placko</name></author><author><name sortKey="Mishra, S" uniqKey="Mishra S">S. Mishra</name></author><author><name sortKey="Weimer, J J" uniqKey="Weimer J">J. J. Weimer</name></author><author><name sortKey="Lucas, L C" uniqKey="Lucas L">L. C. Lucas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mustafa, K" uniqKey="Mustafa K">K. Mustafa</name></author><author><name sortKey="Wennerberg, A" uniqKey="Wennerberg A">A. Wennerberg</name></author><author><name sortKey="Wroblewski, J" uniqKey="Wroblewski J">J. Wroblewski</name></author><author><name sortKey="Hultenby, K" uniqKey="Hultenby K">K. Hultenby</name></author><author><name sortKey="Lopez, B S" uniqKey="Lopez B">B. S. Lopez</name></author><author><name sortKey="Arvidson, K" uniqKey="Arvidson K">K. Arvidson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Le Guehennec, L" uniqKey="Le Guehennec L">L. Le Guéhennec</name></author><author><name sortKey="Soueidan, A" uniqKey="Soueidan A">A. Soueidan</name></author><author><name sortKey="Layrolle, P" uniqKey="Layrolle P">P. Layrolle</name></author><author><name sortKey="Amouriq, Y" uniqKey="Amouriq Y">Y. Amouriq</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aronsson, B O" uniqKey="Aronsson B">B.-O. Aronsson</name></author><author><name sortKey="Lausmaa, J" uniqKey="Lausmaa J">J. Lausmaa</name></author><author><name sortKey="Kasemo, B" uniqKey="Kasemo B">B. Kasemo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Czarnowska, E" uniqKey="Czarnowska E">E. Czarnowska</name></author><author><name sortKey="Wierzcho, T" uniqKey="Wierzcho T">T. Wierzchoń</name></author><author><name sortKey="Maranda Niedbala, A" uniqKey="Maranda Niedbala A">A. Maranda-Niedbała</name></author><author><name sortKey="Karczmarewicz, E" uniqKey="Karczmarewicz E">E. Karczmarewicz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yamamoto, H" uniqKey="Yamamoto H">H. Yamamoto</name></author><author><name sortKey="Shibata, Y" uniqKey="Shibata Y">Y. Shibata</name></author><author><name sortKey="Miyazaki, T" uniqKey="Miyazaki T">T. Miyazaki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alves, C M" uniqKey="Alves C">C. M. Alves</name></author><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y. Yang</name></author><author><name sortKey="Carnes, D L" uniqKey="Carnes D">D. L. Carnes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Webb, K" uniqKey="Webb K">K. Webb</name></author><author><name sortKey="Caldwell, K" uniqKey="Caldwell K">K. Caldwell</name></author><author><name sortKey="Tresco, P A" uniqKey="Tresco P">P. A. Tresco</name></author><author><name sortKey="Keck, W M" uniqKey="Keck W">W. M. Keck</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcclary, K B" uniqKey="Mcclary K">K. B. McClary</name></author><author><name sortKey="Ugarova, T" uniqKey="Ugarova T">T. Ugarova</name></author><author><name sortKey="Grainger, D W" uniqKey="Grainger D">D. W. Grainger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chang, Y C" uniqKey="Chang Y">Y.-C. Chang</name></author><author><name sortKey="Feng, S W" uniqKey="Feng S">S.-W. Feng</name></author><author><name sortKey="Huang, H M" uniqKey="Huang H">H.-M. Huang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chang, Y C" uniqKey="Chang Y">Y. C. Chang</name></author><author><name sortKey="Lee, W" uniqKey="Lee W">W. Lee</name></author><author><name sortKey="Feng, S" uniqKey="Feng S">S. Feng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carlsson, L V" uniqKey="Carlsson L">L. V. Carlsson</name></author><author><name sortKey="Alberktsson, T" uniqKey="Alberktsson T">T. Alberktsson</name></author><author><name sortKey="Berman, C" uniqKey="Berman C">C. Berman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Macdonald, D E" uniqKey="Macdonald D">D. E. MacDonald</name></author><author><name sortKey="Rapuano, B E" uniqKey="Rapuano B">B. E. Rapuano</name></author><author><name sortKey="Vyas, P" uniqKey="Vyas P">P. Vyas</name></author><author><name sortKey="Lane, J M" uniqKey="Lane J">J. M. Lane</name></author><author><name sortKey="Meyers, K" uniqKey="Meyers K">K. Meyers</name></author><author><name sortKey="Wright, T" uniqKey="Wright T">T. Wright</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Andersen, E" uniqKey="Andersen E">E. Andersen</name></author><author><name sortKey="Haanaes, H R" uniqKey="Haanaes H">H. R. Haanaes</name></author><author><name sortKey="Knutsen, B M" uniqKey="Knutsen B">B. M. Knutsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ganeles, J" uniqKey="Ganeles J">J. Ganeles</name></author><author><name sortKey="Rosenberg, M M" uniqKey="Rosenberg M">M. M. Rosenberg</name></author><author><name sortKey="Holt, R L" uniqKey="Holt R">R. L. Holt</name></author><author><name sortKey="Reichman, L H" uniqKey="Reichman L">L. H. Reichman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Berglundh, T" uniqKey="Berglundh T">T. Berglundh</name></author><author><name sortKey="Abrahamsson, I" uniqKey="Abrahamsson I">I. Abrahamsson</name></author><author><name sortKey="Lang, N P" uniqKey="Lang N">N. P. Lang</name></author><author><name sortKey="Lindhe, J" uniqKey="Lindhe J">J. Lindhe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abrahamsson, I" uniqKey="Abrahamsson I">I. Abrahamsson</name></author><author><name sortKey="Berglundh, T" uniqKey="Berglundh T">T. Berglundh</name></author><author><name sortKey="Linder, E" uniqKey="Linder E">E. Linder</name></author><author><name sortKey="Lang, N P" uniqKey="Lang N">N. P. Lang</name></author><author><name sortKey="Lindhe, J" uniqKey="Lindhe J">J. Lindhe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Orsini, G" uniqKey="Orsini G">G. Orsini</name></author><author><name sortKey="Piattelli, M" uniqKey="Piattelli M">M. Piattelli</name></author><author><name sortKey="Scarano, A" uniqKey="Scarano A">A. Scarano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oates, T W" uniqKey="Oates T">T. W. Oates</name></author><author><name sortKey="Valderrama, P" uniqKey="Valderrama P">P. Valderrama</name></author><author><name sortKey="Bischof, M" uniqKey="Bischof M">M. Bischof</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schliephake, H" uniqKey="Schliephake H">H. Schliephake</name></author><author><name sortKey="Sewing, A" uniqKey="Sewing A">A. Sewing</name></author><author><name sortKey="Aref, A" uniqKey="Aref A">A. Aref</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barewal, R M" uniqKey="Barewal R">R. M. Barewal</name></author><author><name sortKey="Oates, T W" uniqKey="Oates T">T. W. Oates</name></author><author><name sortKey="Meredith, N" uniqKey="Meredith N">N. Meredith</name></author><author><name sortKey="Cochran, D L" uniqKey="Cochran D">D. L. Cochran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meredith, N" uniqKey="Meredith N">N. Meredith</name></author><author><name sortKey="Alleyne, D" uniqKey="Alleyne D">D. Alleyne</name></author><author><name sortKey="Cawley, P" uniqKey="Cawley P">P. Cawley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rebaudi, A" uniqKey="Rebaudi A">A. Rebaudi</name></author><author><name sortKey="Koller, B" uniqKey="Koller B">B. Koller</name></author><author><name sortKey="Laib, A" uniqKey="Laib A">A. Laib</name></author><author><name sortKey="Trisi, P" uniqKey="Trisi P">P. Trisi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schouten, C" uniqKey="Schouten C">C. Schouten</name></author><author><name sortKey="Meijer, G J" uniqKey="Meijer G">G. J. Meijer</name></author><author><name sortKey="Van Den Beucken, J J J P" uniqKey="Van Den Beucken J">J. J. J. P. van den Beucken</name></author><author><name sortKey="Spauwen, P H M" uniqKey="Spauwen P">P. H. M. Spauwen</name></author><author><name sortKey="Jansen, J A" uniqKey="Jansen J">J. A. Jansen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ito, M" uniqKey="Ito M">M. Ito</name></author><author><name sortKey="Nakamura, T" uniqKey="Nakamura T">T. Nakamura</name></author><author><name sortKey="Matsumoto, T" uniqKey="Matsumoto T">T. Matsumoto</name></author><author><name sortKey="Tsurusaki, K" uniqKey="Tsurusaki K">K. Tsurusaki</name></author><author><name sortKey="Hayashi, K" uniqKey="Hayashi K">K. Hayashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nelea, V" uniqKey="Nelea V">V. Nelea</name></author><author><name sortKey="Luo, L" uniqKey="Luo L">L. Luo</name></author><author><name sortKey="Demers, C N" uniqKey="Demers C">C. N. Demers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chang, W J" uniqKey="Chang W">W.-J. Chang</name></author><author><name sortKey="Ou, K L" uniqKey="Ou K">K.-L. Ou</name></author><author><name sortKey="Lee, S Y" uniqKey="Lee S">S.-Y. Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schwarz, F" uniqKey="Schwarz F">F. Schwarz</name></author><author><name sortKey="Wieland, M" uniqKey="Wieland M">M. Wieland</name></author><author><name sortKey="Schwartz, Z" uniqKey="Schwartz Z">Z. Schwartz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jimbo, R" uniqKey="Jimbo R">R. Jimbo</name></author><author><name sortKey="Sawase, T" uniqKey="Sawase T">T. Sawase</name></author><author><name sortKey="Shibata, Y" uniqKey="Shibata Y">Y. Shibata</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Petrie, T A" uniqKey="Petrie T">T. A. Petrie</name></author><author><name sortKey="Raynor, J E" uniqKey="Raynor J">J. E. Raynor</name></author><author><name sortKey="Reyes, C D" uniqKey="Reyes C">C. D. Reyes</name></author><author><name sortKey="Burns, K L" uniqKey="Burns K">K. L. Burns</name></author><author><name sortKey="Collard, D M" uniqKey="Collard D">D. M. Collard</name></author><author><name sortKey="Garcia, A J" uniqKey="Garcia A">A. J. García</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Biomed Res Int</journal-id><journal-id journal-id-type="iso-abbrev">Biomed Res Int</journal-id><journal-id journal-id-type="publisher-id">BMRI</journal-id><journal-title-group><journal-title>BioMed Research International</journal-title></journal-title-group><issn pub-type="ppub">2314-6133</issn><issn pub-type="epub">2314-6141</issn><publisher><publisher-name>Hindawi Publishing Corporation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27366739</article-id><article-id pub-id-type="pmc">4913050</article-id><article-id pub-id-type="doi">10.1155/2016/2414809</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Fibronectin-Grafted Titanium Dental Implants: An<italic> In Vivo</italic> Study</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Chang</surname><given-names>Yu-Chi</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Ho</surname><given-names>Kuo-Ning</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Feng</surname><given-names>Sheng-Wei</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Huang</surname><given-names>Haw-Ming</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref><xref ref-type="aff" rid="I2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Chang</surname><given-names>Chia-Hsun</given-names></name><xref ref-type="aff" rid="I3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Lin</surname><given-names>Che-Tong</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref><xref ref-type="aff" rid="I4"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Teng</surname><given-names>Nai-Chia</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref><xref ref-type="aff" rid="I4"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Pan</surname><given-names>Yu Hwa</given-names></name><xref ref-type="aff" rid="I5"><sup>5</sup></xref><xref ref-type="aff" rid="I6"><sup>6</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author"><name><surname>Chang</surname><given-names>Wei-Jen</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref><xref ref-type="aff" rid="I7"><sup>7</sup></xref><xref ref-type="corresp" rid="cor2"><sup>*</sup></xref></contrib></contrib-group><aff id="I1"><sup>1</sup>School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</aff><aff id="I2"><sup>2</sup>Graduate Institute of Biomedical Materials & Tissue Engineering, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan</aff><aff id="I3"><sup>3</sup>Department of International Logistics, Chung-Ang University, Seoul 156756, Republic of Korea</aff><aff id="I4"><sup>4</sup>Dental Department, Taipei Medical University Hospital, Taipei 110, Taiwan</aff><aff id="I5"><sup>5</sup>Department of General Dentistry, Chang Gung Memorial Hospital, Taipei 105, Taiwan</aff><aff id="I6"><sup>6</sup>Graduate Institute of Dental & Craniofacial Science, Chang Gung University, Taoyuan 333, Taiwan</aff><aff id="I7"><sup>7</sup>Dental Department, Taipei Medical University, Shuang-Ho Hospital, Taipei 235, Taiwan</aff><author-notes><corresp id="cor1">*Yu Hwa Pan: <email>shalom.dc@msa.hinet.net</email> and </corresp><corresp id="cor2">*Wei-Jen Chang: <email>m8404006@tmu.edu.tw</email></corresp><fn fn-type="other"><p>Academic Editor: Sandra Rodil</p></fn></author-notes><pub-date pub-type="ppub"><year>2016</year></pub-date><pub-date pub-type="epub"><day>6</day><month>6</month><year>2016</year></pub-date><volume>2016</volume><elocation-id>2414809</elocation-id><history><date date-type="received"><day>13</day><month>1</month><year>2016</year></date><date date-type="rev-recd"><day>23</day><month>3</month><year>2016</year></date><date date-type="accepted"><day>9</day><month>5</month><year>2016</year></date></history><permissions><copyright-statement>Copyright © 2016 Yu-Chi Chang et al.</copyright-statement><copyright-year>2016</copyright-year><license xlink:href="https://creativecommons.org/licenses/by/4.0/"><license-p>This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p>Modification of the physiochemical properties of titanium surfaces using glow discharge plasma (GDP) and fibronectin coating has been shown to enhance the surface hydrophilicity, surface roughness, cell adhesion, migration, and proliferation. This<italic> in vivo</italic> study aimed to evaluate the bone integration efficacy of a biologically modified implant surface. Two different surface-modified implants (Ar-GDP and GDP-fib) were placed in the mandibular premolar area of six beagle dogs for 2–8 weeks. Three techniques [histologic evaluation, resonance frequency analysis (RFA), and microcomputed tomography (micro-CT) evaluation] were used to detect the implant stability and bone-implant contact. The implant stability quotient values of GDP-fib implants were significantly greater than the Ar-GDP implants at 2 and 4 weeks (<italic>P</italic> < 0.01). The bone volume/total volume ratio of GDP-fib implants was greater than the Ar-GDP implants in micro-CT evaluation. A high positive correlation was observed between RFA and micro-CT measurements. At 2 weeks, osteoblasts were seen to line the implant surface, and multinuclear osteoclasts could be seen on the surface of old parent bone. After 8 weeks, a majority of the space in the wound chamber appeared to be replaced by bone. Enhancement of the stability of biologically modified implants was proved by the results of RFA, micro-CT, and histological analysis. This enhanced stability may help fasten treatment and be clinically beneficial.</p></abstract></article-meta></front><floats-group><fig id="fig1" orientation="portrait" position="float"><label>Figure 1</label><caption><p>Experimental implant device: screw-shaped titanium implant packaged with fixture mount. The diameter and length of implant were 3.75 mm and 10 mm, respectively.</p></caption><graphic xlink:href="BMRI2016-2414809.001"></graphic></fig><fig id="fig2" orientation="portrait" position="float"><label>Figure 2</label><caption><p>Schematic of sample preparation.</p></caption><graphic xlink:href="BMRI2016-2414809.002"></graphic></fig><fig id="fig3" orientation="portrait" position="float"><label>Figure 3</label><caption><p>(a) Surgical area before extraction. First, second, third, and fourth premolars in the red box. (b) Surgical area after extraction. (c) Placement of implants.</p></caption><graphic xlink:href="BMRI2016-2414809.003"></graphic></fig><fig id="fig4" orientation="portrait" position="float"><label>Figure 4</label><caption><p>Mean implant stability (implant stability quotient (ISQ) ± SD) of Ar-GDP and GDP-fib implants 2, 4, and 8 weeks after placement. The stability of Ar-GDP implants was significantly lower at 2 and 4 weeks compared to GDP-fib implants (<sup><italic>∗∗</italic></sup><italic>P</italic> < 0.01).</p></caption><graphic xlink:href="BMRI2016-2414809.004"></graphic></fig><fig id="fig5" orientation="portrait" position="float"><label>Figure 5</label><caption><p>Mean values of bone-implant contact calculated by micro-CT analysis.</p></caption><graphic xlink:href="BMRI2016-2414809.005"></graphic></fig><fig id="fig6" orientation="portrait" position="float"><label>Figure 6</label><caption><p>Schematic of Ar-GDP/GDP-fib implants with surrounding bone at 2, 4, and 8 weeks after implantation. (a) Ar-GDP implant at 2 weeks, (b) Ar-GDP implant at 4 weeks, (c) Ar-GDP implant at 8 weeks, (d) GDP-fib implant at 2 weeks, (e) GDP-fib implant at 4 weeks, and (f) GDP-fib implant at 8 weeks.</p></caption><graphic xlink:href="BMRI2016-2414809.006"></graphic></fig><fig id="fig7" orientation="portrait" position="float"><label>Figure 7</label><caption><p>Ground sections of the peri-implant tissue in the GDP-fib and Ar-GDP groups after 2 and 8 weeks of healing. (a) Wound chamber of the GDP-fib implant at 2 weeks, decalcified section, original mag. ×80. (b) Wound chamber of the GDP-fib implant at 8 weeks, decalcified section, original mag. ×80. (c) Wound chamber of the Ar-GDP implant at 2 weeks, decalcified section, original mag. ×80. (d) Wound chamber of the Ar-GDP device at 8 weeks, decalcified section, original mag. ×80.</p></caption><graphic xlink:href="BMRI2016-2414809.007"></graphic></fig><fig id="fig8" orientation="portrait" position="float"><label>Figure 8</label><caption><p>Ground sections of the peri-implant tissue of GDP-fib and Ar-GDP implant surfaces after 2 and 8 weeks of healing. (a) Wound chamber of the GDP-fib implant at 2 weeks. Osteoclasts (<italic>white arrows</italic>) and osteoblasts (<italic>black arrows</italic>) were surrounded by provisional matrix, decalcified section, original mag. ×200. (b) Wound chamber of the GDP-fib implant at 8 weeks. Osteon (#) could be clearly identified, decalcified section, original mag. ×200. (c) Wound chamber of the Ar-GDP implant at 2 weeks. Woven bone (<italic>∗</italic>) formation extending into provisional connective tissue matrix was seen, decalcified section, original mag. ×200. (d) Wound chamber of the Ar-GDP implant at 8 weeks, decalcified section, original mag. ×200.</p></caption><graphic xlink:href="BMRI2016-2414809.008"></graphic></fig><fig id="fig9" orientation="portrait" position="float"><label>Figure 9</label><caption><p>Relationship of the 3D bone-implant contact (BIC) measurements between the BV/TV ratio from CT analysis and the RF data in (a) all, (b) Ar-GDP, and (c) GDP-fib implants.</p></caption><graphic xlink:href="BMRI2016-2414809.009"></graphic></fig></floats-group></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Pmc/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002917 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd -nk 002917 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Pmc
|étape= Curation
|type= RBID
|clé= PMC:4913050
|texte= Fibronectin-Grafted Titanium Dental Implants: An In Vivo Study
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Curation/RBID.i -Sk "pubmed:27366739" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd \
| NlmPubMed2Wicri -a EdenteV2
| This area was generated with Dilib version V0.6.32. |  |