Stem Cells in the Face: Tooth Regeneration and Beyond
Identifieur interne : 002649 ( Pmc/Curation ); précédent : 002648; suivant : 002650Stem Cells in the Face: Tooth Regeneration and Beyond
Auteurs : Jeremy J. Mao [États-Unis] ; Pamela G. Robey [États-Unis] ; Darwin J. Prockop [États-Unis]Source :
- Cell stem cell [ 1934-5909 ] ; 2012.
Abstract
Postnatal orofacial tissues contain rare cells that exhibit stem/progenitor cell properties. Despite a tremendous unmet clinical need for regeneration of tissues lost in congenital anomalies, infections, trauma or tumor resection, how orofacial stem/progenitor cells contribute to tissue development, pathogenesis and regeneration is largely a mystery. This perspective article critically analyzes the current status of orofacial stem/progenitor cells, identifies gaps in our understanding and highlights pathways for the development of regenerative therapies.
Url:
DOI: 10.1016/j.stem.2012.08.010
PubMed: 22958928
PubMed Central: 4093804
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Robey</name><affiliation wicri:level="2"><nlm:aff id="A2">Craniofacital and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Craniofacital and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Prockop, Darwin J" sort="Prockop, Darwin J" uniqKey="Prockop D" first="Darwin J." last="Prockop">Darwin J. Prockop</name><affiliation wicri:level="2"><nlm:aff id="A3">Institute for Regenerative Medicine at Scott and White, Texas A&M University Health Science Center, Temple TX 76502</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Institute for Regenerative Medicine at Scott and White, Texas A&M University Health Science Center</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22958928</idno><idno type="pmc">4093804</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093804</idno><idno type="RBID">PMC:4093804</idno><idno type="doi">10.1016/j.stem.2012.08.010</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">002649</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002649</idno><idno type="wicri:Area/Pmc/Curation">002649</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002649</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Stem Cells in the Face: Tooth Regeneration and Beyond</title><author><name sortKey="Mao, Jeremy J" sort="Mao, Jeremy J" uniqKey="Mao J" first="Jeremy J." last="Mao">Jeremy J. Mao</name><affiliation wicri:level="2"><nlm:aff id="A1">Center for Craniofacial Regeneration, Columbia University Medical Center 630 W. 168 Street – PH7E, New York, NY 10032</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Center for Craniofacial Regeneration, Columbia University Medical Center 630 W. 168 Street – PH7E, New York</wicri:cityArea></affiliation></author><author><name sortKey="Robey, Pamela G" sort="Robey, Pamela G" uniqKey="Robey P" first="Pamela G." last="Robey">Pamela G. Robey</name><affiliation wicri:level="2"><nlm:aff id="A2">Craniofacital and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Craniofacital and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Prockop, Darwin J" sort="Prockop, Darwin J" uniqKey="Prockop D" first="Darwin J." last="Prockop">Darwin J. Prockop</name><affiliation wicri:level="2"><nlm:aff id="A3">Institute for Regenerative Medicine at Scott and White, Texas A&M University Health Science Center, Temple TX 76502</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Institute for Regenerative Medicine at Scott and White, Texas A&M University Health Science Center</wicri:cityArea></affiliation></author></analytic><series><title level="j">Cell stem cell</title><idno type="ISSN">1934-5909</idno><idno type="eISSN">1875-9777</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Postnatal orofacial tissues contain rare cells that exhibit stem/progenitor cell properties. Despite a tremendous unmet clinical need for regeneration of tissues lost in congenital anomalies, infections, trauma or tumor resection, how orofacial stem/progenitor cells contribute to tissue development, pathogenesis and regeneration is largely a mystery. This perspective article critically analyzes the current status of orofacial stem/progenitor cells, identifies gaps in our understanding and highlights pathways for the development of regenerative therapies.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101311472</journal-id><journal-id journal-id-type="pubmed-jr-id">34100</journal-id><journal-id journal-id-type="nlm-ta">Cell Stem Cell</journal-id><journal-id journal-id-type="iso-abbrev">Cell Stem Cell</journal-id><journal-title-group><journal-title>Cell stem cell</journal-title></journal-title-group><issn pub-type="ppub">1934-5909</issn><issn pub-type="epub">1875-9777</issn></journal-meta><article-meta><article-id pub-id-type="pmid">22958928</article-id><article-id pub-id-type="pmc">4093804</article-id><article-id pub-id-type="doi">10.1016/j.stem.2012.08.010</article-id><article-id pub-id-type="manuscript">NIHMS404350</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Stem Cells in the Face: Tooth Regeneration and Beyond</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Mao</surname><given-names>Jeremy J.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Robey</surname><given-names>Pamela G.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Prockop</surname><given-names>Darwin J.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib></contrib-group><aff id="A1"><label>1</label>Center for Craniofacial Regeneration, Columbia University Medical Center 630 W. 168 Street – PH7E, New York, NY 10032</aff><aff id="A2"><label>2</label>Craniofacital and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892</aff><aff id="A3"><label>3</label>Institute for Regenerative Medicine at Scott and White, Texas A&M University Health Science Center, Temple TX 76502</aff><author-notes><corresp id="cor1"><label>*</label><bold>Corresponding author</bold>, Jeremy J. Mao, DDS, PhD, Professor and Edwin S. Robinson Endowed Chair, Co-Director, Center for Craniofacial Regeneration, Columbia University Medical Center, 630 W. 168 St. - PH7E, New York, NY 10032 Phone: 212-305-4475, <email>jmao@columbia.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>8</day><month>6</month><year>2014</year></pub-date><pub-date pub-type="ppub"><day>7</day><month>9</month><year>2012</year></pub-date><pub-date pub-type="pmc-release"><day>11</day><month>7</month><year>2014</year></pub-date><volume>11</volume><issue>3</issue><fpage>291</fpage><lpage>301</lpage><pmc-comment>elocation-id from pubmed: 10.1016/j.stem.2012.08.010</pmc-comment>
<permissions><copyright-statement>© 2012 ll Press. All rights reserved.</copyright-statement><copyright-year>2012</copyright-year></permissions><abstract><p id="P1">Postnatal orofacial tissues contain rare cells that exhibit stem/progenitor cell properties. Despite a tremendous unmet clinical need for regeneration of tissues lost in congenital anomalies, infections, trauma or tumor resection, how orofacial stem/progenitor cells contribute to tissue development, pathogenesis and regeneration is largely a mystery. This perspective article critically analyzes the current status of orofacial stem/progenitor cells, identifies gaps in our understanding and highlights pathways for the development of regenerative therapies.</p></abstract><kwd-group><kwd>dental stem cells</kwd><kwd>dental pulp stem cells</kwd><kwd>periodontal ligament stem cells</kwd><kwd>alveolar bone stem cells</kwd><kwd>bone regeneration</kwd><kwd>tooth regeneration</kwd><kwd>periodontal regeneration</kwd><kwd>scaffolds</kwd><kwd>growth factors</kwd><kwd>animal models</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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