Adenoid cystic carcinoma of the floor of the mouth – A rare presentation
Identifieur interne : 001936 ( Pmc/Curation ); précédent : 001935; suivant : 001937Adenoid cystic carcinoma of the floor of the mouth – A rare presentation
Auteurs : Chandresh Jaiswara [Inde] ; Neeraj Kumar Dhiman [Inde] ; Akhilesh Kumar Singh [Inde] ; Naresh Kumar Sharma [Inde] ; Vishal Verma [Inde] ; Arun Pandey [Inde]Source :
- Journal of Oral Biology and Craniofacial Research [ 2212-4268 ] ; 2015.
Abstract
Adenoid cystic carcinoma (ACC) is an unusual salivary gland malignancy that remains poorly understood. It is a slow growing but aggressive neoplasm with a tendency for recurrence. It is characterized by the proliferation of ductal (luminal) and myoepithelial cells in cribriform, tubular, solid, and cystic forms. Standard treatment, including surgery with postoperative radiation therapy, has attained reasonable local control rates, but distant metastases do not allow any improvement in the survival rate. The understanding of the molecular mechanisms driving ACC is quite rudimentary. We present a case of a 55-year-old female diagnosed with ACC involving the floor of the mouth with an aim to present the carcinoma's behavior, immunohistocytochemistry, the staining pattern, its treatment, and prognosis.
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DOI: 10.1016/j.jobcr.2015.09.007
PubMed: 27900255
PubMed Central: 5122812
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id="aff0005">Assistant Professor, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Assistant Professor, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P.</wicri:regionArea></affiliation></author><author><name sortKey="Singh, Akhilesh Kumar" sort="Singh, Akhilesh Kumar" uniqKey="Singh A" first="Akhilesh Kumar" last="Singh">Akhilesh Kumar Singh</name><affiliation wicri:level="1"><nlm:aff id="aff0010">Service Senior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Service Senior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, 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wicri:level="1"><nlm:aff id="aff0005">Assistant Professor, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Assistant Professor, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P.</wicri:regionArea></affiliation></author><author><name sortKey="Dhiman, Neeraj Kumar" sort="Dhiman, Neeraj Kumar" uniqKey="Dhiman N" first="Neeraj Kumar" last="Dhiman">Neeraj Kumar Dhiman</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Assistant Professor, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Assistant Professor, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P.</wicri:regionArea></affiliation></author><author><name sortKey="Singh, Akhilesh Kumar" sort="Singh, Akhilesh Kumar" uniqKey="Singh A" first="Akhilesh Kumar" last="Singh">Akhilesh Kumar Singh</name><affiliation wicri:level="1"><nlm:aff id="aff0010">Service Senior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Service Senior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P.</wicri:regionArea></affiliation></author><author><name sortKey="Sharma, Naresh Kumar" sort="Sharma, Naresh Kumar" uniqKey="Sharma N" first="Naresh Kumar" last="Sharma">Naresh Kumar Sharma</name><affiliation wicri:level="1"><nlm:aff id="aff0015">Professor & Head, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Professor & Head, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P.</wicri:regionArea></affiliation></author><author><name sortKey="Verma, Vishal" sort="Verma, Vishal" uniqKey="Verma V" first="Vishal" last="Verma">Vishal Verma</name><affiliation wicri:level="1"><nlm:aff id="aff0020">Junior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Junior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P.</wicri:regionArea></affiliation></author><author><name sortKey="Pandey, Arun" sort="Pandey, Arun" uniqKey="Pandey A" first="Arun" last="Pandey">Arun Pandey</name><affiliation wicri:level="1"><nlm:aff id="aff0020">Junior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Junior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P.</wicri:regionArea></affiliation></author></analytic><series><title level="j">Journal of Oral Biology and Craniofacial Research</title><idno type="ISSN">2212-4268</idno><idno type="eISSN">2212-4276</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Adenoid cystic carcinoma (ACC) is an unusual salivary gland malignancy that remains poorly understood. It is a slow growing but aggressive neoplasm with a tendency for recurrence. It is characterized by the proliferation of ductal (luminal) and myoepithelial cells in cribriform, tubular, solid, and cystic forms. Standard treatment, including surgery with postoperative radiation therapy, has attained reasonable local control rates, but distant metastases do not allow any improvement in the survival rate. The understanding of the molecular mechanisms driving ACC is quite rudimentary. We present a case of a 55-year-old female diagnosed with ACC involving the floor of the mouth with an aim to present the carcinoma's behavior, immunohistocytochemistry, the staining pattern, its treatment, and prognosis.</p></div></front></TEI><pmc article-type="brief-report"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Oral Biol Craniofac Res</journal-id><journal-id journal-id-type="iso-abbrev">J Oral Biol Craniofac Res</journal-id><journal-title-group><journal-title>Journal of Oral Biology and Craniofacial Research</journal-title></journal-title-group><issn pub-type="ppub">2212-4268</issn><issn pub-type="epub">2212-4276</issn><publisher><publisher-name>Elsevier</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27900255</article-id><article-id pub-id-type="pmc">5122812</article-id><article-id pub-id-type="publisher-id">S2212-4268(15)00115-3</article-id><article-id pub-id-type="doi">10.1016/j.jobcr.2015.09.007</article-id><article-categories><subj-group subj-group-type="heading"><subject>Short Communication</subject></subj-group></article-categories><title-group><article-title>Adenoid cystic carcinoma of the floor of the mouth – A rare presentation</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Jaiswara</surname><given-names>Chandresh</given-names></name><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Dhiman</surname><given-names>Neeraj Kumar</given-names></name><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Singh</surname><given-names>Akhilesh Kumar</given-names></name><email>georgianaks@gmail.com</email><xref rid="aff0010" ref-type="aff">b</xref><xref rid="cor0005" ref-type="corresp">⁎</xref></contrib><contrib contrib-type="author"><name><surname>Sharma</surname><given-names>Naresh Kumar</given-names></name><xref rid="aff0015" ref-type="aff">c</xref></contrib><contrib contrib-type="author"><name><surname>Verma</surname><given-names>Vishal</given-names></name><xref rid="aff0020" ref-type="aff">d</xref></contrib><contrib contrib-type="author"><name><surname>Pandey</surname><given-names>Arun</given-names></name><xref rid="aff0020" ref-type="aff">d</xref></contrib></contrib-group><aff id="aff0005"><label>a</label>Assistant Professor, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India</aff><aff id="aff0010"><label>b</label>Service Senior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India</aff><aff id="aff0015"><label>c</label>Professor & Head, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India</aff><aff id="aff0020"><label>d</label>Junior Resident, Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India</aff><author-notes><corresp id="cor0005"><label>⁎</label><italic>Corresponding author</italic>. <email>georgianaks@gmail.com</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>24</day><month>10</month><year>2015</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>11</month><year>2016</year></pub-date><pub-date pub-type="epub"><day>24</day><month>10</month><year>2015</year></pub-date><volume>6</volume><issue>Suppl 1</issue><fpage>S65</fpage><lpage>S69</lpage><history><date date-type="received"><day>18</day><month>9</month><year>2015</year></date><date date-type="accepted"><day>28</day><month>9</month><year>2015</year></date></history><permissions><copyright-statement>© 2015 Craniofacial Research Foundation. All rights reserved.</copyright-statement><copyright-year>2015</copyright-year><copyright-holder>Craniofacial Research Foundation</copyright-holder></permissions><abstract id="abs0005"><p>Adenoid cystic carcinoma (ACC) is an unusual salivary gland malignancy that remains poorly understood. It is a slow growing but aggressive neoplasm with a tendency for recurrence. It is characterized by the proliferation of ductal (luminal) and myoepithelial cells in cribriform, tubular, solid, and cystic forms. Standard treatment, including surgery with postoperative radiation therapy, has attained reasonable local control rates, but distant metastases do not allow any improvement in the survival rate. The understanding of the molecular mechanisms driving ACC is quite rudimentary. We present a case of a 55-year-old female diagnosed with ACC involving the floor of the mouth with an aim to present the carcinoma's behavior, immunohistocytochemistry, the staining pattern, its treatment, and prognosis.</p></abstract><kwd-group id="kwd0005"><title>Keywords</title><kwd>Adenoid cystic carcinoma</kwd><kwd>Minor salivary gland</kwd><kwd>Floor of the mouth</kwd><kwd>Malignant</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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