Scurvy and vitamin C deficiency in Crohn's disease.
Identifieur interne : 001638 ( Pmc/Curation ); précédent : 001637; suivant : 001639Scurvy and vitamin C deficiency in Crohn's disease.
Auteurs : B. D. LinakerSource :
- Postgraduate Medical Journal [ 0032-5473 ] ; 1979.
Abstract
A case of scurvy presenting in a patient with Crohn's disease is reported. A normal response to replacement therapy is seen. Vitamin C (ascorbic acid) deficiency was found in 7 out of 10 patients with clinically quiescent Crohn's disease, 4 of whom had an adequate oral intake of vitamin C. There was no significant difference in oral intake between patients with Crohn's disease and matched controls but there was a significant difference (P less than 0.001) in leucocyte ascorbic acid levels. It is recommended that patients with Crohn's disease be screened for vitamin C deficiency and receive prophylactic vitamin C supplements daily.
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PubMed: 432168
PubMed Central: 2425408
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<front><div type="abstract" xml:lang="en"><p>A case of scurvy presenting in a patient with Crohn's disease is reported. A normal response to replacement therapy is seen. Vitamin C (ascorbic acid) deficiency was found in 7 out of 10 patients with clinically quiescent Crohn's disease, 4 of whom had an adequate oral intake of vitamin C. There was no significant difference in oral intake between patients with Crohn's disease and matched controls but there was a significant difference (P less than 0.001) in leucocyte ascorbic acid levels. It is recommended that patients with Crohn's disease be screened for vitamin C deficiency and receive prophylactic vitamin C supplements daily.</p>
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Postgrad Med J</journal-id>
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<title-group><article-title>Scurvy and vitamin C deficiency in Crohn's disease.</article-title>
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<pub-date pub-type="ppub"><month>1</month>
<year>1979</year>
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<volume>55</volume>
<issue>639</issue>
<fpage>26</fpage>
<lpage>29</lpage>
<abstract><p>A case of scurvy presenting in a patient with Crohn's disease is reported. A normal response to replacement therapy is seen. Vitamin C (ascorbic acid) deficiency was found in 7 out of 10 patients with clinically quiescent Crohn's disease, 4 of whom had an adequate oral intake of vitamin C. There was no significant difference in oral intake between patients with Crohn's disease and matched controls but there was a significant difference (P less than 0.001) in leucocyte ascorbic acid levels. It is recommended that patients with Crohn's disease be screened for vitamin C deficiency and receive prophylactic vitamin C supplements daily.</p>
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