Osteoradionecrosis of the Jaws: Clinico-Therapeutic Management: A Literature Review and Update
Identifieur interne : 000E17 ( Pmc/Curation ); précédent : 000E16; suivant : 000E18Osteoradionecrosis of the Jaws: Clinico-Therapeutic Management: A Literature Review and Update
Auteurs : Koteswara Rao Nadella [Inde] ; Rama Mohan Kodali [Inde] ; Leela Krishna Guttikonda [Inde] ; Ashok Jonnalagadda [Inde]Source :
- Journal of Maxillofacial & Oral Surgery [ 0972-8279 ] ; 2015.
Abstract
Osteoradionecrosis is one of the most serious oral complications of head and neck cancer treatment. It is a severe delayed radiation-induced injury, characterized by bone tissue necrosis and failure to heal for at least 3 months. In most cases osteoradionecrosis gradually progresses, becoming more extensive and painful that leads to infection and pathological fracture. The present paper provides a literature review and update on the risk factors underlying osteoradionecrosis, its clinical and diagnostic particulars, prevention and most widely accepted treatment options including the latest treatment modalities. Lastly, a new early management protocol is proposed based on the current clinical criteria relating to osteonecrosis secondary to treatment with bisphosphonates, together with the adoption of new therapies supported by increased levels of evidence.
Url:
DOI: 10.1007/s12663-015-0762-9
PubMed: 26604460
PubMed Central: 4648774
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Sudha & Nageswara Rao, Siddhartha Institute of Dental Sciences, Chinnaoutpalli, Gannavaram, Vijayawada</wicri:regionArea></affiliation></author><author><name sortKey="Guttikonda, Leela Krishna" sort="Guttikonda, Leela Krishna" uniqKey="Guttikonda L" first="Leela Krishna" last="Guttikonda">Leela Krishna Guttikonda</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Department of Oral and Maxillofacial Surgery, Drs. Sudha & Nageswara Rao, Siddhartha Institute of Dental Sciences, Chinnaoutpalli, Gannavaram, Vijayawada, 521286 India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Oral and Maxillofacial Surgery, Drs. Sudha & Nageswara Rao, Siddhartha Institute of Dental Sciences, Chinnaoutpalli, Gannavaram, Vijayawada</wicri:regionArea></affiliation></author><author><name sortKey="Jonnalagadda, Ashok" sort="Jonnalagadda, Ashok" uniqKey="Jonnalagadda A" first="Ashok" last="Jonnalagadda">Ashok Jonnalagadda</name><affiliation wicri:level="1"><nlm:aff id="Aff1">Department of Oral and Maxillofacial Surgery, Drs. Sudha & Nageswara Rao, Siddhartha Institute of Dental Sciences, Chinnaoutpalli, Gannavaram, Vijayawada, 521286 India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Oral and Maxillofacial Surgery, Drs. 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The present paper provides a literature review and update on the risk factors underlying osteoradionecrosis, its clinical and diagnostic particulars, prevention and most widely accepted treatment options including the latest treatment modalities. Lastly, a new early management protocol is proposed based on the current clinical criteria relating to osteonecrosis secondary to treatment with bisphosphonates, together with the adoption of new therapies supported by increased levels of evidence.
</p></div></front></TEI><pmc article-type="review-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Maxillofac Oral Surg</journal-id><journal-id journal-id-type="iso-abbrev">J Maxillofac Oral Surg</journal-id><journal-title-group><journal-title>Journal of Maxillofacial & Oral Surgery</journal-title></journal-title-group><issn pub-type="ppub">0972-8279</issn><issn pub-type="epub">0974-942X</issn><publisher><publisher-name>Springer India</publisher-name><publisher-loc>New Delhi</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26604460</article-id><article-id pub-id-type="pmc">4648774</article-id><article-id pub-id-type="publisher-id">762</article-id><article-id pub-id-type="doi">10.1007/s12663-015-0762-9</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review Paper</subject></subj-group></article-categories><title-group><article-title>Osteoradionecrosis of the Jaws: Clinico-Therapeutic Management: A Literature Review and Update</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Nadella</surname><given-names>Koteswara Rao</given-names></name><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Kodali</surname><given-names>Rama Mohan</given-names></name><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Guttikonda</surname><given-names>Leela Krishna</given-names></name><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Jonnalagadda</surname><given-names>Ashok</given-names></name><address><email>dr.ashokjonnalagaddamds@gmail.com</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><aff id="Aff1">Department of Oral and Maxillofacial Surgery, Drs. Sudha & Nageswara Rao, Siddhartha Institute of Dental Sciences, Chinnaoutpalli, Gannavaram, Vijayawada, 521286 India</aff></contrib-group><pub-date pub-type="epub"><day>10</day><month>3</month><year>2015</year></pub-date><pub-date pub-type="ppub"><month>12</month><year>2015</year></pub-date><volume>14</volume><issue>4</issue><fpage>891</fpage><lpage>901</lpage><history><date date-type="received"><day>13</day><month>6</month><year>2014</year></date><date date-type="accepted"><day>16</day><month>2</month><year>2015</year></date></history><permissions><copyright-statement>© The Association of Oral and Maxillofacial Surgeons of India 2015</copyright-statement></permissions><abstract id="Abs1"><p>Osteoradionecrosis is one of the most serious oral complications of head and neck cancer treatment. It is a severe delayed radiation-induced injury, characterized by bone tissue necrosis and failure to heal for at least 3 months. In most cases osteoradionecrosis gradually progresses, becoming more extensive and painful that leads to infection and pathological fracture. The present paper provides a literature review and update on the risk factors underlying osteoradionecrosis, its clinical and diagnostic particulars, prevention and most widely accepted treatment options including the latest treatment modalities. Lastly, a new early management protocol is proposed based on the current clinical criteria relating to osteonecrosis secondary to treatment with bisphosphonates, together with the adoption of new therapies supported by increased levels of evidence.
</p></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>Osteoradionecrosis</kwd><kwd>Etiology</kwd><kwd>Pathophysiology</kwd><kwd>Risk factors</kwd><kwd>Treatment options</kwd><kwd>Bisphosphonate osteonecrosis</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© The Association of Oral and Maxillofacial Surgeons of India 2015</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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