Osseointegration of standard and mini dental implants: a histomorphometric comparison
Identifieur interne : 000C92 ( Pmc/Curation ); précédent : 000C91; suivant : 000C93Osseointegration of standard and mini dental implants: a histomorphometric comparison
Auteurs : Jagjit S. Dhaliwal ; Rubens F. Albuquerque ; Monzur Murshed ; Jocelyne S. FeineSource :
- International Journal of Implant Dentistry [ 2198-4034 ] ; 2017.
Abstract
Mini dental implants (MDIs) are becoming increasingly popular for rehabilitation of edentulous patients because of their several advantages. However, there is a lack of evidence on the osseointegration potential of the MDIs. The objective of the study was to histomorphometrically evaluate and compare bone apposition on the surface of MDIs and standard implants in a rabbit model.
Nine New Zealand white rabbits were used for the study to meet statistical criteria for adequate power. Total 18 3M™ESPE™ MDIs and 18 standard implants (Ankylos® Friadent, Dentsply) were inserted randomly into the tibia of rabbits (four implants per rabbit); animals were sacrificed after a 6-week healing period. The specimens were retrieved en bloc and preserved in 10% formaldehyde solution. Specimens were prepared for embedding in a light cure acrylic resin (Technovit 9100). The most central sagittal histological sections (30–40 μm thick) were obtained using a Leica SP 1600 saw microtome. After staining, the Leica DM2000 microscope was used, the images were captured using Olympus DP72 camera and associated software. Bone implant contact (BIC) was measured using Infinity Analyze software.
All implants were osseointegrated. Histologic measures show mineralized bone matrix in intimate contact with the implant surface in both groups. The median BIC was 58.5 % (IQR 8.0) in the MDI group and 57.0 % (IQR 5.5) in the control group (
Based on these results, it is concluded that osseointegration of MDIs is similar to that of standard implants.
Url:
DOI: 10.1186/s40729-017-0079-1
PubMed: 28462508
PubMed Central: 5411366
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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p id="Par1">Mini dental implants (MDIs) are becoming increasingly popular for rehabilitation of edentulous patients because of their several advantages. However, there is a lack of evidence on the osseointegration potential of the MDIs. The objective of the study was to histomorphometrically evaluate and compare bone apposition on the surface of MDIs and standard implants in a rabbit model.</p>
</sec>
<sec><title>Methods</title>
<p id="Par2">Nine New Zealand white rabbits were used for the study to meet statistical criteria for adequate power. Total 18 3M<sup>™</sup>
ESPE<sup>™</sup>
MDIs and 18 standard implants (Ankylos<sup>®</sup>
Friadent, Dentsply) were inserted randomly into the tibia of rabbits (four implants per rabbit); animals were sacrificed after a 6-week healing period. The specimens were retrieved en bloc and preserved in 10% formaldehyde solution. Specimens were prepared for embedding in a light cure acrylic resin (Technovit 9100). The most central sagittal histological sections (30–40 μm thick) were obtained using a Leica SP 1600 saw microtome. After staining, the Leica DM2000 microscope was used, the images were captured using Olympus DP72 camera and associated software. Bone implant contact (BIC) was measured using Infinity Analyze software.</p>
</sec>
<sec><title>Results</title>
<p id="Par3">All implants were osseointegrated. Histologic measures show mineralized bone matrix in intimate contact with the implant surface in both groups. The median BIC was 58.5 % (IQR 8.0) in the MDI group and 57.0 % (IQR 5.5) in the control group (<italic>P ></italic>
0.05; Mann-Whitney test). There were no statistical differences in osseointegration at 6 weeks between MDIs and standard implants in rabbit tibias.</p>
</sec>
<sec><title>Conclusions</title>
<p id="Par4">Based on these results, it is concluded that osseointegration of MDIs is similar to that of standard implants.</p>
</sec>
</div>
</front>
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<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Int J Implant Dent</journal-id>
<journal-id journal-id-type="iso-abbrev">Int J Implant Dent</journal-id>
<journal-title-group><journal-title>International Journal of Implant Dentistry</journal-title>
</journal-title-group>
<issn pub-type="epub">2198-4034</issn>
<publisher><publisher-name>Springer Berlin Heidelberg</publisher-name>
<publisher-loc>Berlin/Heidelberg</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">28462508</article-id>
<article-id pub-id-type="pmc">5411366</article-id>
<article-id pub-id-type="publisher-id">79</article-id>
<article-id pub-id-type="doi">10.1186/s40729-017-0079-1</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Research</subject>
</subj-group>
</article-categories>
<title-group><article-title>Osseointegration of standard and mini dental implants: a histomorphometric comparison</article-title>
</title-group>
<contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Dhaliwal</surname>
<given-names>Jagjit S.</given-names>
</name>
<address><phone>+1- 514-398-7203</phone>
<phone>+91-9814020131</phone>
<email>jagjitd2002@yahoo.com</email>
</address>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Albuquerque</surname>
<given-names>Rubens F.</given-names>
<suffix>Jr</suffix>
</name>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Murshed</surname>
<given-names>Monzur</given-names>
</name>
<xref ref-type="aff" rid="Aff1">1</xref>
<xref ref-type="aff" rid="Aff3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Feine</surname>
<given-names>Jocelyne S.</given-names>
</name>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<aff id="Aff1"><label>1</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1936 8649</institution-id>
<institution-id institution-id-type="GRID">grid.14709.3b</institution-id>
<institution>Faculty of Dentistry,</institution>
<institution>McGill University,</institution>
</institution-wrap>
2001 McGill College Avenue, Suite 500, Montreal, Quebec H3A 1G1 Canada</aff>
<aff id="Aff2"><label>2</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 0722</institution-id>
<institution-id institution-id-type="GRID">grid.11899.38</institution-id>
<institution>Faculty of Dentistry of Ribeirão Preto,</institution>
<institution>University of São Paulo,</institution>
</institution-wrap>
Ribeirão Preto, SP Brazil</aff>
<aff id="Aff3"><label>3</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1936 8649</institution-id>
<institution-id institution-id-type="GRID">grid.14709.3b</institution-id>
<institution>Department of Medicine,</institution>
<institution>McGill University,</institution>
</institution-wrap>
Montreal, Quebec Canada</aff>
</contrib-group>
<pub-date pub-type="epub"><day>1</day>
<month>5</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>1</day>
<month>5</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="collection"><month>12</month>
<year>2017</year>
</pub-date>
<volume>3</volume>
<elocation-id>15</elocation-id>
<history><date date-type="received"><day>22</day>
<month>2</month>
<year>2017</year>
</date>
<date date-type="accepted"><day>26</day>
<month>4</month>
<year>2017</year>
</date>
</history>
<permissions><copyright-statement>© The Author(s). 2017</copyright-statement>
<license license-type="OpenAccess"><license-p><bold>Open Access</bold>
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</ext-link>
), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.</license-p>
</license>
</permissions>
<abstract id="Abs1"><sec><title>Background</title>
<p id="Par1">Mini dental implants (MDIs) are becoming increasingly popular for rehabilitation of edentulous patients because of their several advantages. However, there is a lack of evidence on the osseointegration potential of the MDIs. The objective of the study was to histomorphometrically evaluate and compare bone apposition on the surface of MDIs and standard implants in a rabbit model.</p>
</sec>
<sec><title>Methods</title>
<p id="Par2">Nine New Zealand white rabbits were used for the study to meet statistical criteria for adequate power. Total 18 3M<sup>™</sup>
ESPE<sup>™</sup>
MDIs and 18 standard implants (Ankylos<sup>®</sup>
Friadent, Dentsply) were inserted randomly into the tibia of rabbits (four implants per rabbit); animals were sacrificed after a 6-week healing period. The specimens were retrieved en bloc and preserved in 10% formaldehyde solution. Specimens were prepared for embedding in a light cure acrylic resin (Technovit 9100). The most central sagittal histological sections (30–40 μm thick) were obtained using a Leica SP 1600 saw microtome. After staining, the Leica DM2000 microscope was used, the images were captured using Olympus DP72 camera and associated software. Bone implant contact (BIC) was measured using Infinity Analyze software.</p>
</sec>
<sec><title>Results</title>
<p id="Par3">All implants were osseointegrated. Histologic measures show mineralized bone matrix in intimate contact with the implant surface in both groups. The median BIC was 58.5 % (IQR 8.0) in the MDI group and 57.0 % (IQR 5.5) in the control group (<italic>P ></italic>
0.05; Mann-Whitney test). There were no statistical differences in osseointegration at 6 weeks between MDIs and standard implants in rabbit tibias.</p>
</sec>
<sec><title>Conclusions</title>
<p id="Par4">Based on these results, it is concluded that osseointegration of MDIs is similar to that of standard implants.</p>
</sec>
</abstract>
<kwd-group xml:lang="en"><title>Keywords</title>
<kwd>Bone implant contact</kwd>
<kwd>Mini dental implant</kwd>
<kwd>Osseointegration</kwd>
</kwd-group>
<funding-group><award-group><funding-source><institution>3M ESPE</institution>
</funding-source>
<award-id>A10-M118-9A.</award-id>
<principal-award-recipient><name><surname>Dhaliwal</surname>
<given-names>Jagjit S.</given-names>
</name>
</principal-award-recipient>
</award-group>
<award-group><funding-source><institution-wrap><institution-id institution-id-type="FundRef">http://dx.doi.org/10.13039/501100001411</institution-id>
<institution>Indian Council of Medical Research</institution>
</institution-wrap>
</funding-source>
</award-group>
<award-group><funding-source><institution-wrap><institution-id institution-id-type="FundRef">http://dx.doi.org/10.13039/100008919</institution-id>
<institution>Faculty of Dentistry, McGill University</institution>
</institution-wrap>
</funding-source>
</award-group>
</funding-group>
<custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name>
<meta-value>© The Author(s) 2017</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
</record>
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