Posterior Teeth Occlusion Associated with Cognitive Function in Nursing Home Older Residents: A Cross-Sectional Observational Study
Identifieur interne : 000426 ( Pmc/Curation ); précédent : 000425; suivant : 000427Posterior Teeth Occlusion Associated with Cognitive Function in Nursing Home Older Residents: A Cross-Sectional Observational Study
Auteurs : Kenji Takeuchi [Japon] ; Maya Izumi [Japon] ; Michiko Furuta [Japon] ; Toru Takeshita [Japon] ; Yukie Shibata [Japon] ; Shinya Kageyama [Japon] ; Seijun Ganaha [Japon] ; Yoshihisa Yamashita [Japon]Source :
- PLoS ONE [ 1932-6203 ] ; 2015.
Abstract
Early detection and subsequent reduction of modifiable risk factors for cognitive decline is important for extending healthy life expectancy in the currently aging society. Although a recent increase in studies on the state or number of the teeth and cognitive function, few studies have focused on the association between posterior teeth occlusion necessary to maintain chewing function and cognitive function among older adults. This study examined the association between posterior teeth occlusion and cognitive function in nursing home older residents. In this cross-sectional study, 279 residents aged ≥60 years from eight nursing homes in Aso City, Japan participated in cognitive function and dental status assessments and completed a comprehensive questionnaire survey in 2014. Cognitive function was measured using a Mini-Mental State Examination (MMSE). Posterior teeth occlusion was assessed using a total number of functional tooth units (total-FTUs), depending on the number and location of the remaining natural and artificial teeth on implant-supported, fixed, and removable prostheses. Linear regression models were used to assess univariate and multivariate associations between total-FTUs and MMSE scores. Models were sequentially adjusted for demographic characteristics, number of natural teeth, socioeconomic status, health behaviors, comorbidities, physical function, and nutritional status. Among the 200 residents included in our analysis, mean MMSE scores and total-FTUs were 11.0 ± 8.6 and 9.3 ± 4.6, respectively. Higher total-FTUs were significantly associated with higher MMSE scores after adjustment for demographics and teeth number (B = 0.48, 95% confidence interval [CI] = 0.22–0.74). The association remained significant even after adjustment for all covariates (B = 0.25, 95% CI = 0.01–0.49). The current findings demonstrated that loss of posterior teeth occlusion was independently associated with cognitive decline in nursing home older residents in Japan. Maintenance and restoration of posterior teeth occlusion may be a preventive factor against cognitive decline in aged populations.
Url:
DOI: 10.1371/journal.pone.0141737
PubMed: 26512900
PubMed Central: 4626072
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000426
Links to Exploration step
PMC:4626072Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Posterior Teeth Occlusion Associated with Cognitive Function in Nursing Home Older Residents: A Cross-Sectional Observational Study</title>
<author><name sortKey="Takeuchi, Kenji" sort="Takeuchi, Kenji" uniqKey="Takeuchi K" first="Kenji" last="Takeuchi">Kenji Takeuchi</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Izumi, Maya" sort="Izumi, Maya" uniqKey="Izumi M" first="Maya" last="Izumi">Maya Izumi</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Furuta, Michiko" sort="Furuta, Michiko" uniqKey="Furuta M" first="Michiko" last="Furuta">Michiko Furuta</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Takeshita, Toru" sort="Takeshita, Toru" uniqKey="Takeshita T" first="Toru" last="Takeshita">Toru Takeshita</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shibata, Yukie" sort="Shibata, Yukie" uniqKey="Shibata Y" first="Yukie" last="Shibata">Yukie Shibata</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kageyama, Shinya" sort="Kageyama, Shinya" uniqKey="Kageyama S" first="Shinya" last="Kageyama">Shinya Kageyama</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ganaha, Seijun" sort="Ganaha, Seijun" uniqKey="Ganaha S" first="Seijun" last="Ganaha">Seijun Ganaha</name>
<affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Kizuna-kai, Aso-kizuna Dental Clinic, Aso, Kumamoto, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Kizuna-kai, Aso-kizuna Dental Clinic, Aso, Kumamoto</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yamashita, Yoshihisa" sort="Yamashita, Yoshihisa" uniqKey="Yamashita Y" first="Yoshihisa" last="Yamashita">Yoshihisa Yamashita</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">26512900</idno>
<idno type="pmc">4626072</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626072</idno>
<idno type="RBID">PMC:4626072</idno>
<idno type="doi">10.1371/journal.pone.0141737</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">000426</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000426</idno>
<idno type="wicri:Area/Pmc/Curation">000426</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000426</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Posterior Teeth Occlusion Associated with Cognitive Function in Nursing Home Older Residents: A Cross-Sectional Observational Study</title>
<author><name sortKey="Takeuchi, Kenji" sort="Takeuchi, Kenji" uniqKey="Takeuchi K" first="Kenji" last="Takeuchi">Kenji Takeuchi</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Izumi, Maya" sort="Izumi, Maya" uniqKey="Izumi M" first="Maya" last="Izumi">Maya Izumi</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Furuta, Michiko" sort="Furuta, Michiko" uniqKey="Furuta M" first="Michiko" last="Furuta">Michiko Furuta</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Takeshita, Toru" sort="Takeshita, Toru" uniqKey="Takeshita T" first="Toru" last="Takeshita">Toru Takeshita</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Shibata, Yukie" sort="Shibata, Yukie" uniqKey="Shibata Y" first="Yukie" last="Shibata">Yukie Shibata</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kageyama, Shinya" sort="Kageyama, Shinya" uniqKey="Kageyama S" first="Shinya" last="Kageyama">Shinya Kageyama</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ganaha, Seijun" sort="Ganaha, Seijun" uniqKey="Ganaha S" first="Seijun" last="Ganaha">Seijun Ganaha</name>
<affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Kizuna-kai, Aso-kizuna Dental Clinic, Aso, Kumamoto, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Kizuna-kai, Aso-kizuna Dental Clinic, Aso, Kumamoto</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yamashita, Yoshihisa" sort="Yamashita, Yoshihisa" uniqKey="Yamashita Y" first="Yoshihisa" last="Yamashita">Yoshihisa Yamashita</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">PLoS ONE</title>
<idno type="eISSN">1932-6203</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Early detection and subsequent reduction of modifiable risk factors for cognitive decline is important for extending healthy life expectancy in the currently aging society. Although a recent increase in studies on the state or number of the teeth and cognitive function, few studies have focused on the association between posterior teeth occlusion necessary to maintain chewing function and cognitive function among older adults. This study examined the association between posterior teeth occlusion and cognitive function in nursing home older residents. In this cross-sectional study, 279 residents aged ≥60 years from eight nursing homes in Aso City, Japan participated in cognitive function and dental status assessments and completed a comprehensive questionnaire survey in 2014. Cognitive function was measured using a Mini-Mental State Examination (MMSE). Posterior teeth occlusion was assessed using a total number of functional tooth units (total-FTUs), depending on the number and location of the remaining natural and artificial teeth on implant-supported, fixed, and removable prostheses. Linear regression models were used to assess univariate and multivariate associations between total-FTUs and MMSE scores. Models were sequentially adjusted for demographic characteristics, number of natural teeth, socioeconomic status, health behaviors, comorbidities, physical function, and nutritional status. Among the 200 residents included in our analysis, mean MMSE scores and total-FTUs were 11.0 ± 8.6 and 9.3 ± 4.6, respectively. Higher total-FTUs were significantly associated with higher MMSE scores after adjustment for demographics and teeth number (B = 0.48, 95% confidence interval [CI] = 0.22–0.74). The association remained significant even after adjustment for all covariates (B = 0.25, 95% CI = 0.01–0.49). The current findings demonstrated that loss of posterior teeth occlusion was independently associated with cognitive decline in nursing home older residents in Japan. Maintenance and restoration of posterior teeth occlusion may be a preventive factor against cognitive decline in aged populations.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Dewey, Me" uniqKey="Dewey M">ME Dewey</name>
</author>
<author><name sortKey="Saz, P" uniqKey="Saz P">P Saz</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Daviglus, Ml" uniqKey="Daviglus M">ML Daviglus</name>
</author>
<author><name sortKey="Bell, Cc" uniqKey="Bell C">CC Bell</name>
</author>
<author><name sortKey="Berrettini, W" uniqKey="Berrettini W">W Berrettini</name>
</author>
<author><name sortKey="Bowen, Pe" uniqKey="Bowen P">PE Bowen</name>
</author>
<author><name sortKey="Connolly, Es" uniqKey="Connolly E">ES Connolly</name>
</author>
<author><name sortKey="Cox, Nj" uniqKey="Cox N">NJ Cox</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Qaseem, A" uniqKey="Qaseem A">A Qaseem</name>
</author>
<author><name sortKey="Snow, V" uniqKey="Snow V">V Snow</name>
</author>
<author><name sortKey="Cross, Jt" uniqKey="Cross J">JT Cross</name>
</author>
<author><name sortKey="Forciea, Ma" uniqKey="Forciea M">MA Forciea</name>
</author>
<author><name sortKey="Hopkins, R" uniqKey="Hopkins R">R Hopkins</name>
</author>
<author><name sortKey="Shekelle, P" uniqKey="Shekelle P">P Shekelle</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zimmerman, S" uniqKey="Zimmerman S">S Zimmerman</name>
</author>
<author><name sortKey="Anderson, Wl" uniqKey="Anderson W">WL Anderson</name>
</author>
<author><name sortKey="Brode, S" uniqKey="Brode S">S Brode</name>
</author>
<author><name sortKey="Jonas, D" uniqKey="Jonas D">D Jonas</name>
</author>
<author><name sortKey="Lux, L" uniqKey="Lux L">L Lux</name>
</author>
<author><name sortKey="Beeber, As" uniqKey="Beeber A">AS Beeber</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Batty, Gd" uniqKey="Batty G">GD Batty</name>
</author>
<author><name sortKey="Li, Q" uniqKey="Li Q">Q Li</name>
</author>
<author><name sortKey="Huxley, R" uniqKey="Huxley R">R Huxley</name>
</author>
<author><name sortKey="Zoungas, S" uniqKey="Zoungas S">S Zoungas</name>
</author>
<author><name sortKey="Taylor, Ba" uniqKey="Taylor B">BA Taylor</name>
</author>
<author><name sortKey="Neal, B" uniqKey="Neal B">B Neal</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Okamoto, N" uniqKey="Okamoto N">N Okamoto</name>
</author>
<author><name sortKey="Morikawa, M" uniqKey="Morikawa M">M Morikawa</name>
</author>
<author><name sortKey="Tomioka, K" uniqKey="Tomioka K">K Tomioka</name>
</author>
<author><name sortKey="Yanagi, M" uniqKey="Yanagi M">M Yanagi</name>
</author>
<author><name sortKey="Amano, N" uniqKey="Amano N">N Amano</name>
</author>
<author><name sortKey="Kurumatani, N" uniqKey="Kurumatani N">N Kurumatani</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yamamoto, T" uniqKey="Yamamoto T">T Yamamoto</name>
</author>
<author><name sortKey="Kondo, K" uniqKey="Kondo K">K Kondo</name>
</author>
<author><name sortKey="Hirai, H" uniqKey="Hirai H">H Hirai</name>
</author>
<author><name sortKey="Nakade, M" uniqKey="Nakade M">M Nakade</name>
</author>
<author><name sortKey="Aida, J" uniqKey="Aida J">J Aida</name>
</author>
<author><name sortKey="Hirata, Y" uniqKey="Hirata Y">Y Hirata</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Naorungroj, S" uniqKey="Naorungroj S">S Naorungroj</name>
</author>
<author><name sortKey="Schoenbach, Vj" uniqKey="Schoenbach V">VJ Schoenbach</name>
</author>
<author><name sortKey="Wruck, L" uniqKey="Wruck L">L Wruck</name>
</author>
<author><name sortKey="Mosley, Th" uniqKey="Mosley T">TH Mosley</name>
</author>
<author><name sortKey="Gottesman, Rf" uniqKey="Gottesman R">RF Gottesman</name>
</author>
<author><name sortKey="Alonso, A" uniqKey="Alonso A">A Alonso</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tsakos, G" uniqKey="Tsakos G">G Tsakos</name>
</author>
<author><name sortKey="Watt, Rg" uniqKey="Watt R">RG Watt</name>
</author>
<author><name sortKey="Rouxel, Pl" uniqKey="Rouxel P">PL Rouxel</name>
</author>
<author><name sortKey="De Oliveira, C" uniqKey="De Oliveira C">C de Oliveira</name>
</author>
<author><name sortKey="Demakakos, P" uniqKey="Demakakos P">P Demakakos</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kaye, Ek" uniqKey="Kaye E">EK Kaye</name>
</author>
<author><name sortKey="Valencia, A" uniqKey="Valencia A">A Valencia</name>
</author>
<author><name sortKey="Baba, N" uniqKey="Baba N">N Baba</name>
</author>
<author><name sortKey="Spiro, A" uniqKey="Spiro A">A Spiro</name>
</author>
<author><name sortKey="Dietrich, T" uniqKey="Dietrich T">T Dietrich</name>
</author>
<author><name sortKey="Garcia, Ri" uniqKey="Garcia R">RI Garcia</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Moriya, S" uniqKey="Moriya S">S Moriya</name>
</author>
<author><name sortKey="Tei, K" uniqKey="Tei K">K Tei</name>
</author>
<author><name sortKey="Murata, A" uniqKey="Murata A">A Murata</name>
</author>
<author><name sortKey="Yamazaki, Y" uniqKey="Yamazaki Y">Y Yamazaki</name>
</author>
<author><name sortKey="Hata, H" uniqKey="Hata H">H Hata</name>
</author>
<author><name sortKey="Muramatsu, M" uniqKey="Muramatsu M">M Muramatsu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Folstein, Mf" uniqKey="Folstein M">MF Folstein</name>
</author>
<author><name sortKey="Folstein, Se" uniqKey="Folstein S">SE Folstein</name>
</author>
<author><name sortKey="Mchugh, Pr" uniqKey="Mchugh P">PR McHugh</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ueno, M" uniqKey="Ueno M">M Ueno</name>
</author>
<author><name sortKey="Yanagisawa, T" uniqKey="Yanagisawa T">T Yanagisawa</name>
</author>
<author><name sortKey="Shinada, K" uniqKey="Shinada K">K Shinada</name>
</author>
<author><name sortKey="Ohara, S" uniqKey="Ohara S">S Ohara</name>
</author>
<author><name sortKey="Kawaguchi, Y" uniqKey="Kawaguchi Y">Y Kawaguchi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yamamoto, T" uniqKey="Yamamoto T">T Yamamoto</name>
</author>
<author><name sortKey="Kondo, K" uniqKey="Kondo K">K Kondo</name>
</author>
<author><name sortKey="Aida, J" uniqKey="Aida J">J Aida</name>
</author>
<author><name sortKey="Fuchida, S" uniqKey="Fuchida S">S Fuchida</name>
</author>
<author><name sortKey="Hirata, Y" uniqKey="Hirata Y">Y Hirata</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Charlson, Me" uniqKey="Charlson M">ME Charlson</name>
</author>
<author><name sortKey="Pompei, P" uniqKey="Pompei P">P Pompei</name>
</author>
<author><name sortKey="Ales, Kl" uniqKey="Ales K">KL Ales</name>
</author>
<author><name sortKey="Mackenzie, Cr" uniqKey="Mackenzie C">CR MacKenzie</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mahoney, Fi" uniqKey="Mahoney F">FI Mahoney</name>
</author>
<author><name sortKey="Barthel, Dw" uniqKey="Barthel D">DW Barthel</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kaiser, Mj" uniqKey="Kaiser M">MJ Kaiser</name>
</author>
<author><name sortKey="Bauer, Jm" uniqKey="Bauer J">JM Bauer</name>
</author>
<author><name sortKey="Ramsch, C" uniqKey="Ramsch C">C Ramsch</name>
</author>
<author><name sortKey="Uter, W" uniqKey="Uter W">W Uter</name>
</author>
<author><name sortKey="Guigoz, Y" uniqKey="Guigoz Y">Y Guigoz</name>
</author>
<author><name sortKey="Cederholm, T" uniqKey="Cederholm T">T Cederholm</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Von Elm, E" uniqKey="Von Elm E">E von Elm</name>
</author>
<author><name sortKey="Altman, Dg" uniqKey="Altman D">DG Altman</name>
</author>
<author><name sortKey="Egger, M" uniqKey="Egger M">M Egger</name>
</author>
<author><name sortKey="Pocock, Sj" uniqKey="Pocock S">SJ Pocock</name>
</author>
<author><name sortKey="G Tzsche, Pc" uniqKey="G Tzsche P">PC Gøtzsche</name>
</author>
<author><name sortKey="Vandenbroucke, Jp" uniqKey="Vandenbroucke J">JP Vandenbroucke</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Furuta, M" uniqKey="Furuta M">M Furuta</name>
</author>
<author><name sortKey="Komiya Nonaka, M" uniqKey="Komiya Nonaka M">M Komiya-Nonaka</name>
</author>
<author><name sortKey="Akifusa, S" uniqKey="Akifusa S">S Akifusa</name>
</author>
<author><name sortKey="Shimazaki, Y" uniqKey="Shimazaki Y">Y Shimazaki</name>
</author>
<author><name sortKey="Adachi, M" uniqKey="Adachi M">M Adachi</name>
</author>
<author><name sortKey="Kinoshita, T" uniqKey="Kinoshita T">T Kinoshita</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Brayne, C" uniqKey="Brayne C">C Brayne</name>
</author>
<author><name sortKey="Calloway, P" uniqKey="Calloway P">P Calloway</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ragonese, P" uniqKey="Ragonese P">P Ragonese</name>
</author>
<author><name sortKey="Aridon, P" uniqKey="Aridon P">P Aridon</name>
</author>
<author><name sortKey="D Amelio, M" uniqKey="D Amelio M">M D'Amelio</name>
</author>
<author><name sortKey="Aiello, F" uniqKey="Aiello F">F Aiello</name>
</author>
<author><name sortKey="Antonietta Mazzola, M" uniqKey="Antonietta Mazzola M">M Antonietta Mazzola</name>
</author>
<author><name sortKey="Realmuto, S" uniqKey="Realmuto S">S Realmuto</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Formiga, F" uniqKey="Formiga F">F Formiga</name>
</author>
<author><name sortKey="Fort, I" uniqKey="Fort I">I Fort</name>
</author>
<author><name sortKey="Robles, Mj" uniqKey="Robles M">MJ Robles</name>
</author>
<author><name sortKey="Riu, S" uniqKey="Riu S">S Riu</name>
</author>
<author><name sortKey="Sabartes, O" uniqKey="Sabartes O">O Sabartes</name>
</author>
<author><name sortKey="Barranco, E" uniqKey="Barranco E">E Barranco</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Malara, A" uniqKey="Malara A">A Malara</name>
</author>
<author><name sortKey="Sgr, G" uniqKey="Sgr G">G Sgrò</name>
</author>
<author><name sortKey="Caruso, C" uniqKey="Caruso C">C Caruso</name>
</author>
<author><name sortKey="Ceravolo, F" uniqKey="Ceravolo F">F Ceravolo</name>
</author>
<author><name sortKey="Curinga, G" uniqKey="Curinga G">G Curinga</name>
</author>
<author><name sortKey="Renda, Gf" uniqKey="Renda G">GF Renda</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sheiham, A" uniqKey="Sheiham A">A Sheiham</name>
</author>
<author><name sortKey="Steele, Jg" uniqKey="Steele J">JG Steele</name>
</author>
<author><name sortKey="Marcenes, W" uniqKey="Marcenes W">W Marcenes</name>
</author>
<author><name sortKey="Lowe, C" uniqKey="Lowe C">C Lowe</name>
</author>
<author><name sortKey="Finch, S" uniqKey="Finch S">S Finch</name>
</author>
<author><name sortKey="Bates, Cj" uniqKey="Bates C">CJ Bates</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lindroos, E" uniqKey="Lindroos E">E Lindroos</name>
</author>
<author><name sortKey="Saarela, Rk" uniqKey="Saarela R">RK Saarela</name>
</author>
<author><name sortKey="Soini, H" uniqKey="Soini H">H Soini</name>
</author>
<author><name sortKey="Muurinen, S" uniqKey="Muurinen S">S Muurinen</name>
</author>
<author><name sortKey="Suominen, Mh" uniqKey="Suominen M">MH Suominen</name>
</author>
<author><name sortKey="Pitk L, Kh" uniqKey="Pitk L K">KH Pitkälä</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Saarela, Rk" uniqKey="Saarela R">RK Saarela</name>
</author>
<author><name sortKey="Soini, H" uniqKey="Soini H">H Soini</name>
</author>
<author><name sortKey="Hiltunen, K" uniqKey="Hiltunen K">K Hiltunen</name>
</author>
<author><name sortKey="Muurinen, S" uniqKey="Muurinen S">S Muurinen</name>
</author>
<author><name sortKey="Suominen, M" uniqKey="Suominen M">M Suominen</name>
</author>
<author><name sortKey="Pitk L, K" uniqKey="Pitk L K">K Pitkälä</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Takeuchi, K" uniqKey="Takeuchi K">K Takeuchi</name>
</author>
<author><name sortKey="Aida, J" uniqKey="Aida J">J Aida</name>
</author>
<author><name sortKey="Ito, K" uniqKey="Ito K">K Ito</name>
</author>
<author><name sortKey="Furuta, M" uniqKey="Furuta M">M Furuta</name>
</author>
<author><name sortKey="Yamashita, Y" uniqKey="Yamashita Y">Y Yamashita</name>
</author>
<author><name sortKey="Osaka, K" uniqKey="Osaka K">K Osaka</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Samnieng, P" uniqKey="Samnieng P">P Samnieng</name>
</author>
<author><name sortKey="Ueno, M" uniqKey="Ueno M">M Ueno</name>
</author>
<author><name sortKey="Shinada, K" uniqKey="Shinada K">K Shinada</name>
</author>
<author><name sortKey="Zaitsu, T" uniqKey="Zaitsu T">T Zaitsu</name>
</author>
<author><name sortKey="Wright, Fa" uniqKey="Wright F">FA Wright</name>
</author>
<author><name sortKey="Kawaguchi, Y" uniqKey="Kawaguchi Y">Y Kawaguchi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gillette Guyonnet, S" uniqKey="Gillette Guyonnet S">S Gillette Guyonnet</name>
</author>
<author><name sortKey="Abellan Van Kan, G" uniqKey="Abellan Van Kan G">G Abellan Van Kan</name>
</author>
<author><name sortKey="Andrieu, S" uniqKey="Andrieu S">S Andrieu</name>
</author>
<author><name sortKey="Barberger Gateau, P" uniqKey="Barberger Gateau P">P Barberger Gateau</name>
</author>
<author><name sortKey="Berr, C" uniqKey="Berr C">C Berr</name>
</author>
<author><name sortKey="Bonnefoy, M" uniqKey="Bonnefoy M">M Bonnefoy</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gonzalez, S" uniqKey="Gonzalez S">S González</name>
</author>
<author><name sortKey="Huerta, Jm" uniqKey="Huerta J">JM Huerta</name>
</author>
<author><name sortKey="Fernandez, S" uniqKey="Fernandez S">S Fernández</name>
</author>
<author><name sortKey="Patterson, Am" uniqKey="Patterson A">AM Patterson</name>
</author>
<author><name sortKey="Lasheras, C" uniqKey="Lasheras C">C Lasheras</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Momose, T" uniqKey="Momose T">T Momose</name>
</author>
<author><name sortKey="Nishikawa, J" uniqKey="Nishikawa J">J Nishikawa</name>
</author>
<author><name sortKey="Watanabe, T" uniqKey="Watanabe T">T Watanabe</name>
</author>
<author><name sortKey="Sasaki, Y" uniqKey="Sasaki Y">Y Sasaki</name>
</author>
<author><name sortKey="Senda, M" uniqKey="Senda M">M Senda</name>
</author>
<author><name sortKey="Kubota, K" uniqKey="Kubota K">K Kubota</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Onozuka, M" uniqKey="Onozuka M">M Onozuka</name>
</author>
<author><name sortKey="Fujita, M" uniqKey="Fujita M">M Fujita</name>
</author>
<author><name sortKey="Watanabe, K" uniqKey="Watanabe K">K Watanabe</name>
</author>
<author><name sortKey="Hirano, Y" uniqKey="Hirano Y">Y Hirano</name>
</author>
<author><name sortKey="Niwa, M" uniqKey="Niwa M">M Niwa</name>
</author>
<author><name sortKey="Nishiyama, K" uniqKey="Nishiyama K">K Nishiyama</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hirano, Y" uniqKey="Hirano Y">Y Hirano</name>
</author>
<author><name sortKey="Obata, T" uniqKey="Obata T">T Obata</name>
</author>
<author><name sortKey="Kashikura, K" uniqKey="Kashikura K">K Kashikura</name>
</author>
<author><name sortKey="Nonaka, H" uniqKey="Nonaka H">H Nonaka</name>
</author>
<author><name sortKey="Tachibana, A" uniqKey="Tachibana A">A Tachibana</name>
</author>
<author><name sortKey="Ikehira, H" uniqKey="Ikehira H">H Ikehira</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ono, Y" uniqKey="Ono Y">Y Ono</name>
</author>
<author><name sortKey="Yamamoto, T" uniqKey="Yamamoto T">T Yamamoto</name>
</author>
<author><name sortKey="Kubo, Ky" uniqKey="Kubo K">KY Kubo</name>
</author>
<author><name sortKey="Onozuka, M" uniqKey="Onozuka M">M Onozuka</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Elsig, F" uniqKey="Elsig F">F Elsig</name>
</author>
<author><name sortKey="Schimmel, M" uniqKey="Schimmel M">M Schimmel</name>
</author>
<author><name sortKey="Duvernay, E" uniqKey="Duvernay E">E Duvernay</name>
</author>
<author><name sortKey="Giannelli, Sv" uniqKey="Giannelli S">SV Giannelli</name>
</author>
<author><name sortKey="Graf, Ce" uniqKey="Graf C">CE Graf</name>
</author>
<author><name sortKey="Carlier, S" uniqKey="Carlier S">S Carlier</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kimura, Y" uniqKey="Kimura Y">Y Kimura</name>
</author>
<author><name sortKey="Ogawa, H" uniqKey="Ogawa H">H Ogawa</name>
</author>
<author><name sortKey="Yoshihara, A" uniqKey="Yoshihara A">A Yoshihara</name>
</author>
<author><name sortKey="Yamaga, T" uniqKey="Yamaga T">T Yamaga</name>
</author>
<author><name sortKey="Takiguchi, T" uniqKey="Takiguchi T">T Takiguchi</name>
</author>
<author><name sortKey="Wada, T" uniqKey="Wada T">T Wada</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lexomboon, D" uniqKey="Lexomboon D">D Lexomboon</name>
</author>
<author><name sortKey="Trulsson, M" uniqKey="Trulsson M">M Trulsson</name>
</author>
<author><name sortKey="W Rdh, I" uniqKey="W Rdh I">I Wårdh</name>
</author>
<author><name sortKey="Parker, Mg" uniqKey="Parker M">MG Parker</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Miura, H" uniqKey="Miura H">H Miura</name>
</author>
<author><name sortKey="Yamasaki, K" uniqKey="Yamasaki K">K Yamasaki</name>
</author>
<author><name sortKey="Kariyasu, M" uniqKey="Kariyasu M">M Kariyasu</name>
</author>
<author><name sortKey="Miura, K" uniqKey="Miura K">K Miura</name>
</author>
<author><name sortKey="Sumi, Y" uniqKey="Sumi Y">Y Sumi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name>
</author>
<author><name sortKey="Iinuma, M" uniqKey="Iinuma M">M Iinuma</name>
</author>
<author><name sortKey="Onozuka, M" uniqKey="Onozuka M">M Onozuka</name>
</author>
<author><name sortKey="Kubo, Ky" uniqKey="Kubo K">KY Kubo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ferri, Cp" uniqKey="Ferri C">CP Ferri</name>
</author>
<author><name sortKey="Prince, M" uniqKey="Prince M">M Prince</name>
</author>
<author><name sortKey="Brayne, C" uniqKey="Brayne C">C Brayne</name>
</author>
<author><name sortKey="Brodaty, H" uniqKey="Brodaty H">H Brodaty</name>
</author>
<author><name sortKey="Fratiglioni, L" uniqKey="Fratiglioni L">L Fratiglioni</name>
</author>
<author><name sortKey="Ganguli, M" uniqKey="Ganguli M">M Ganguli</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sekita, A" uniqKey="Sekita A">A Sekita</name>
</author>
<author><name sortKey="Ninomiya, T" uniqKey="Ninomiya T">T Ninomiya</name>
</author>
<author><name sortKey="Tanizaki, Y" uniqKey="Tanizaki Y">Y Tanizaki</name>
</author>
<author><name sortKey="Doi, Y" uniqKey="Doi Y">Y Doi</name>
</author>
<author><name sortKey="Hata, J" uniqKey="Hata J">J Hata</name>
</author>
<author><name sortKey="Yonemoto, K" uniqKey="Yonemoto K">K Yonemoto</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Searle, Sd" uniqKey="Searle S">SD Searle</name>
</author>
<author><name sortKey="Rockwood, K" uniqKey="Rockwood K">K Rockwood</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yaffe, K" uniqKey="Yaffe K">K Yaffe</name>
</author>
<author><name sortKey="Blackwell, T" uniqKey="Blackwell T">T Blackwell</name>
</author>
<author><name sortKey="Gore, R" uniqKey="Gore R">R Gore</name>
</author>
<author><name sortKey="Sands, L" uniqKey="Sands L">L Sands</name>
</author>
<author><name sortKey="Reus, V" uniqKey="Reus V">V Reus</name>
</author>
<author><name sortKey="Browner, Ws" uniqKey="Browner W">WS Browner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rosenberg, Pb" uniqKey="Rosenberg P">PB Rosenberg</name>
</author>
<author><name sortKey="Mielke, Mm" uniqKey="Mielke M">MM Mielke</name>
</author>
<author><name sortKey="Han, D" uniqKey="Han D">D Han</name>
</author>
<author><name sortKey="Leoutsakos, Js" uniqKey="Leoutsakos J">JS Leoutsakos</name>
</author>
<author><name sortKey="Lyketsos, Cg" uniqKey="Lyketsos C">CG Lyketsos</name>
</author>
<author><name sortKey="Rabins, Pv" uniqKey="Rabins P">PV Rabins</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">PLoS One</journal-id>
<journal-id journal-id-type="iso-abbrev">PLoS ONE</journal-id>
<journal-id journal-id-type="publisher-id">plos</journal-id>
<journal-id journal-id-type="pmc">plosone</journal-id>
<journal-title-group><journal-title>PLoS ONE</journal-title>
</journal-title-group>
<issn pub-type="epub">1932-6203</issn>
<publisher><publisher-name>Public Library of Science</publisher-name>
<publisher-loc>San Francisco, CA USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">26512900</article-id>
<article-id pub-id-type="pmc">4626072</article-id>
<article-id pub-id-type="doi">10.1371/journal.pone.0141737</article-id>
<article-id pub-id-type="publisher-id">PONE-D-15-28157</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Posterior Teeth Occlusion Associated with Cognitive Function in Nursing Home Older Residents: A Cross-Sectional Observational Study</article-title>
<alt-title alt-title-type="running-head">Posterior Teeth Occlusion and Cognitive Function</alt-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Takeuchi</surname>
<given-names>Kenji</given-names>
</name>
<xref ref-type="aff" rid="aff001"><sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Izumi</surname>
<given-names>Maya</given-names>
</name>
<xref ref-type="aff" rid="aff001"><sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Furuta</surname>
<given-names>Michiko</given-names>
</name>
<xref ref-type="aff" rid="aff001"><sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Takeshita</surname>
<given-names>Toru</given-names>
</name>
<xref ref-type="aff" rid="aff001"><sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Shibata</surname>
<given-names>Yukie</given-names>
</name>
<xref ref-type="aff" rid="aff001"><sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kageyama</surname>
<given-names>Shinya</given-names>
</name>
<xref ref-type="aff" rid="aff001"><sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ganaha</surname>
<given-names>Seijun</given-names>
</name>
<xref ref-type="aff" rid="aff002"><sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yamashita</surname>
<given-names>Yoshihisa</given-names>
</name>
<xref ref-type="aff" rid="aff001"><sup>1</sup>
</xref>
<xref rid="cor001" ref-type="corresp">*</xref>
</contrib>
</contrib-group>
<aff id="aff001"><label>1</label>
<addr-line>Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Fukuoka, Japan</addr-line>
</aff>
<aff id="aff002"><label>2</label>
<addr-line>Kizuna-kai, Aso-kizuna Dental Clinic, Aso, Kumamoto, Japan</addr-line>
</aff>
<contrib-group><contrib contrib-type="editor"><name><surname>Fuh</surname>
<given-names>Jong-Ling</given-names>
</name>
<role>Editor</role>
<xref ref-type="aff" rid="edit1"></xref>
</contrib>
</contrib-group>
<aff id="edit1"><addr-line>Taipei Veterans General Hospital, TAIWAN</addr-line>
</aff>
<author-notes><fn fn-type="conflict" id="coi001"><p><bold>Competing Interests: </bold>
The authors have declared that no competing interests exist.</p>
</fn>
<fn fn-type="con" id="contrib001"><p>Conceived and designed the experiments: KT MI YY. Performed the experiments: KT MI SK SG. Analyzed the data: KT MF. Contributed reagents/materials/analysis tools: TT YS SG. Wrote the paper: KT YY.</p>
</fn>
<corresp id="cor001">* E-mail: <email>yoshi@dent.kyushu-u.ac.jp</email>
</corresp>
</author-notes>
<pub-date pub-type="epub"><day>29</day>
<month>10</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="collection"><year>2015</year>
</pub-date>
<volume>10</volume>
<issue>10</issue>
<elocation-id>e0141737</elocation-id>
<history><date date-type="received"><day>29</day>
<month>6</month>
<year>2015</year>
</date>
<date date-type="accepted"><day>11</day>
<month>10</month>
<year>2015</year>
</date>
</history>
<permissions><copyright-year>2015</copyright-year>
<copyright-holder>Takeuchi et al</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link>
, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited</license-p>
</license>
</permissions>
<self-uri content-type="pdf" xlink:type="simple" xlink:href="pone.0141737.pdf"></self-uri>
<abstract><p>Early detection and subsequent reduction of modifiable risk factors for cognitive decline is important for extending healthy life expectancy in the currently aging society. Although a recent increase in studies on the state or number of the teeth and cognitive function, few studies have focused on the association between posterior teeth occlusion necessary to maintain chewing function and cognitive function among older adults. This study examined the association between posterior teeth occlusion and cognitive function in nursing home older residents. In this cross-sectional study, 279 residents aged ≥60 years from eight nursing homes in Aso City, Japan participated in cognitive function and dental status assessments and completed a comprehensive questionnaire survey in 2014. Cognitive function was measured using a Mini-Mental State Examination (MMSE). Posterior teeth occlusion was assessed using a total number of functional tooth units (total-FTUs), depending on the number and location of the remaining natural and artificial teeth on implant-supported, fixed, and removable prostheses. Linear regression models were used to assess univariate and multivariate associations between total-FTUs and MMSE scores. Models were sequentially adjusted for demographic characteristics, number of natural teeth, socioeconomic status, health behaviors, comorbidities, physical function, and nutritional status. Among the 200 residents included in our analysis, mean MMSE scores and total-FTUs were 11.0 ± 8.6 and 9.3 ± 4.6, respectively. Higher total-FTUs were significantly associated with higher MMSE scores after adjustment for demographics and teeth number (B = 0.48, 95% confidence interval [CI] = 0.22–0.74). The association remained significant even after adjustment for all covariates (B = 0.25, 95% CI = 0.01–0.49). The current findings demonstrated that loss of posterior teeth occlusion was independently associated with cognitive decline in nursing home older residents in Japan. Maintenance and restoration of posterior teeth occlusion may be a preventive factor against cognitive decline in aged populations.</p>
</abstract>
<funding-group><funding-statement>The authors have no support or funding to report.</funding-statement>
</funding-group>
<counts><fig-count count="0"></fig-count>
<table-count count="3"></table-count>
<page-count count="11"></page-count>
</counts>
<custom-meta-group><custom-meta id="data-availability"><meta-name>Data Availability</meta-name>
<meta-value>Data are available upon request due to ethical restrictions. Interested researchers must be approved by the Kyushu University Institutional Review Board for Clinical Research. Thus, to request the data, please contact Dr. Yoshihisa Yamashita, Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University. Email: (<email>yoshi@dent.kyushu-u.ac.jp</email>
).</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
<notes><title>Data Availability</title>
<p>Data are available upon request due to ethical restrictions. Interested researchers must be approved by the Kyushu University Institutional Review Board for Clinical Research. Thus, to request the data, please contact Dr. Yoshihisa Yamashita, Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University. Email: (<email>yoshi@dent.kyushu-u.ac.jp</email>
).</p>
</notes>
</front>
</pmc>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Pmc/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000426 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd -nk 000426 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= EdenteV2 |flux= Pmc |étape= Curation |type= RBID |clé= PMC:4626072 |texte= Posterior Teeth Occlusion Associated with Cognitive Function in Nursing Home Older Residents: A Cross-Sectional Observational Study }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Curation/RBID.i -Sk "pubmed:26512900" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd \ | NlmPubMed2Wicri -a EdenteV2
![]() | This area was generated with Dilib version V0.6.32. | ![]() |