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Efficacy of sonic-powered toothbrushes for plaque removal in patients with peri-implant mucositis

Identifieur interne : 000360 ( Pmc/Curation ); précédent : 000359; suivant : 000361

Efficacy of sonic-powered toothbrushes for plaque removal in patients with peri-implant mucositis

Auteurs : Jungwon Lee [Corée du Sud] ; Jong Heun Lim [Corée du Sud] ; Jungeun Lee [Corée du Sud] ; Sungtae Kim [Corée du Sud] ; Ki-Tae Koo [Corée du Sud] ; Yang-Jo Seol [Corée du Sud] ; Young Ku [Corée du Sud] ; Yong-Moo Lee [Corée du Sud] ; In-Chul Rhyu [Corée du Sud]

Source :

RBID : PMC:4415002

Abstract

Purpose

The aim of this study was to evaluate the effectiveness of powered toothbrushes for plaque control in patients with peri-implant mucositis, in comparison with manual toothbrushes.

Methods

This randomized, prospective, controlled, clinical parallel study compared the efficacy of manual and powered toothbrushes for plaque control in implant restorations. Patients with bleeding on probing, no residual pocket depth (as indicated by a pocket probing depth ≥ 5 mm), and no radiological peri-implant bone loss were eligible for this study. Patients were requested to complete a questionnaire describing their oral hygiene habits. The duration and frequency of tooth brushing were recorded by subjects in order to assess their compliance. Clinical parameters, including the modified plaque index (mPI), the modified sulcus bleeding index (mSBI), and clinical photographs (buccal and lingual views) were recorded at baseline and at one-month and two-month follow-up visits.

Results

Statistically significant differences between patients who used manual toothbrushes and those who used powered toothbrushes were found regarding the frequency of tooth brushing per day and the duration of brushing at one-month and two-month follow-up visits, while no statistically significant differences were found relating to other oral hygiene habits. A statistically significant difference in patient compliance for tooth brushing was found at one month, while no difference was found at two months. Statistically significant decreases in the mPI and the mSBI were observed in both groups from baseline to the one- and two-month follow-ups. The overall reduction of these parameters was not significantly different between the two groups, except for mPI reduction between baseline and one month of follow-up.

Conclusions

Sonic-powered toothbrushes may be a useful device for plaque control in patients with peri-implant mucositis.

Graphical Abstract


Url:
DOI: 10.5051/jpis.2015.45.2.56
PubMed: 25932339
PubMed Central: 4415002

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PMC:4415002

Le document en format XML

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<title>Purpose</title>
<p>The aim of this study was to evaluate the effectiveness of powered toothbrushes for plaque control in patients with peri-implant mucositis, in comparison with manual toothbrushes.</p>
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<sec>
<title>Methods</title>
<p>This randomized, prospective, controlled, clinical parallel study compared the efficacy of manual and powered toothbrushes for plaque control in implant restorations. Patients with bleeding on probing, no residual pocket depth (as indicated by a pocket probing depth ≥ 5 mm), and no radiological peri-implant bone loss were eligible for this study. Patients were requested to complete a questionnaire describing their oral hygiene habits. The duration and frequency of tooth brushing were recorded by subjects in order to assess their compliance. Clinical parameters, including the modified plaque index (mPI), the modified sulcus bleeding index (mSBI), and clinical photographs (buccal and lingual views) were recorded at baseline and at one-month and two-month follow-up visits.</p>
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<title>Results</title>
<p>Statistically significant differences between patients who used manual toothbrushes and those who used powered toothbrushes were found regarding the frequency of tooth brushing per day and the duration of brushing at one-month and two-month follow-up visits, while no statistically significant differences were found relating to other oral hygiene habits. A statistically significant difference in patient compliance for tooth brushing was found at one month, while no difference was found at two months. Statistically significant decreases in the mPI and the mSBI were observed in both groups from baseline to the one- and two-month follow-ups. The overall reduction of these parameters was not significantly different between the two groups, except for mPI reduction between baseline and one month of follow-up.</p>
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<title>Conclusions</title>
<p>Sonic-powered toothbrushes may be a useful device for plaque control in patients with peri-implant mucositis.</p>
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</TEI>
<pmc article-type="research-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">J Periodontal Implant Sci</journal-id>
<journal-id journal-id-type="iso-abbrev">J Periodontal Implant Sci</journal-id>
<journal-id journal-id-type="publisher-id">JPIS</journal-id>
<journal-title-group>
<journal-title>Journal of Periodontal & Implant Science</journal-title>
</journal-title-group>
<issn pub-type="ppub">2093-2278</issn>
<issn pub-type="epub">2093-2286</issn>
<publisher>
<publisher-name>Korean Academy of Periodontology</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">25932339</article-id>
<article-id pub-id-type="pmc">4415002</article-id>
<article-id pub-id-type="doi">10.5051/jpis.2015.45.2.56</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Research Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Efficacy of sonic-powered toothbrushes for plaque removal in patients with peri-implant mucositis</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-5508-442X</contrib-id>
<name>
<surname>Lee</surname>
<given-names>Jungwon</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-8034-8976</contrib-id>
<name>
<surname>Lim</surname>
<given-names>Jong heun</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0001-8921-984X</contrib-id>
<name>
<surname>Lee</surname>
<given-names>Jungeun</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0001-6361-4104</contrib-id>
<name>
<surname>Kim</surname>
<given-names>Sungtae</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-9809-2630</contrib-id>
<name>
<surname>Koo</surname>
<given-names>Ki-Tae</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-2076-5452</contrib-id>
<name>
<surname>Seol</surname>
<given-names>Yang-Jo</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0001-5682-0604</contrib-id>
<name>
<surname>Ku</surname>
<given-names>Young</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-5619-3847</contrib-id>
<name>
<surname>Lee</surname>
<given-names>Yong-Moo</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0003-4110-6381</contrib-id>
<name>
<surname>Rhyu</surname>
<given-names>In-Chul</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
</contrib-group>
<aff id="A1">
<label>1</label>
Department of Periodontology, Seoul National University School of Dentistry, Seoul, Korea.</aff>
<aff id="A2">
<label>2</label>
The Armed Forces Medical Command, Seongnam, Korea.</aff>
<author-notes>
<corresp>Correspondence: In-Chul Rhyu. Department of Periodontology, Seoul National University School of Dentistry, 101 Daehak-ro, Jongno-gu, Seoul 110-768, Korea.
<email>icrhyu@snu.ac.kr</email>
, Tel: +82-2-2072-3858, Fax: +82-2-744-0051</corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>4</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="epub">
<day>29</day>
<month>4</month>
<year>2015</year>
</pub-date>
<volume>45</volume>
<issue>2</issue>
<fpage>56</fpage>
<lpage>61</lpage>
<history>
<date date-type="received">
<day>17</day>
<month>2</month>
<year>2015</year>
</date>
<date date-type="accepted">
<day>27</day>
<month>3</month>
<year>2015</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright © 2015 Korean Academy of Periodontology</copyright-statement>
<copyright-year>2015</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">
<license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (
<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">http://creativecommons.org/licenses/by-nc/3.0/</ext-link>
).</license-p>
</license>
</permissions>
<abstract abstract-type="graphical">
<sec>
<title>Purpose</title>
<p>The aim of this study was to evaluate the effectiveness of powered toothbrushes for plaque control in patients with peri-implant mucositis, in comparison with manual toothbrushes.</p>
</sec>
<sec>
<title>Methods</title>
<p>This randomized, prospective, controlled, clinical parallel study compared the efficacy of manual and powered toothbrushes for plaque control in implant restorations. Patients with bleeding on probing, no residual pocket depth (as indicated by a pocket probing depth ≥ 5 mm), and no radiological peri-implant bone loss were eligible for this study. Patients were requested to complete a questionnaire describing their oral hygiene habits. The duration and frequency of tooth brushing were recorded by subjects in order to assess their compliance. Clinical parameters, including the modified plaque index (mPI), the modified sulcus bleeding index (mSBI), and clinical photographs (buccal and lingual views) were recorded at baseline and at one-month and two-month follow-up visits.</p>
</sec>
<sec>
<title>Results</title>
<p>Statistically significant differences between patients who used manual toothbrushes and those who used powered toothbrushes were found regarding the frequency of tooth brushing per day and the duration of brushing at one-month and two-month follow-up visits, while no statistically significant differences were found relating to other oral hygiene habits. A statistically significant difference in patient compliance for tooth brushing was found at one month, while no difference was found at two months. Statistically significant decreases in the mPI and the mSBI were observed in both groups from baseline to the one- and two-month follow-ups. The overall reduction of these parameters was not significantly different between the two groups, except for mPI reduction between baseline and one month of follow-up.</p>
</sec>
<sec>
<title>Conclusions</title>
<p>Sonic-powered toothbrushes may be a useful device for plaque control in patients with peri-implant mucositis.</p>
</sec>
<sec>
<title>Graphical Abstract</title>
<p content-type="graphical">
<graphic xlink:href="jpis-45-56-ab001.jpg" position="float" orientation="portrait"></graphic>
</p>
</sec>
</abstract>
<kwd-group>
<kwd>Dental implant</kwd>
<kwd>Dental plaque</kwd>
<kwd>Oral hygiene</kwd>
</kwd-group>
<funding-group>
<award-group>
<funding-source country="KR">Philips Corporation</funding-source>
</award-group>
</funding-group>
</article-meta>
</front>
<floats-group>
<fig id="F1" orientation="portrait" position="float">
<label>Figure 1</label>
<caption>
<title>Clinical assessments of the modified plaque index (mPI) and the modified sulcus bleeding index (mSBI) at the implant sites by visit and group. An overall pattern of reduction in the mPI and mSBI was observed post-baseline in both groups. In addition, in the powered toothbrush group, a statistically significant reduction of the mSBI was found between one month and two months of follow-up.</title>
<p>
<sup>a)</sup>
<italic>P</italic>
<0.05 compared to the baseline in the manual toothbrush group.</p>
<p>
<sup>b)</sup>
<italic>P</italic>
<0.05 compared to the baseline in the powered toothbrush group.</p>
<p>
<sup>c)</sup>
<italic>P</italic>
<0.05 compared to the baseline and one month of follow-up in the powered toothbrush group.</p>
</caption>
<graphic xlink:href="jpis-45-56-g001"></graphic>
</fig>
<table-wrap id="T1" orientation="portrait" position="float">
<label>Table 1</label>
<caption>
<title>Description of subjects and implants by toothbrush group.</title>
</caption>
<alternatives>
<graphic xlink:href="jpis-45-56-i001"></graphic>
<table frame="hsides" rules="rows">
<thead>
<tr>
<th valign="middle" align="center" rowspan="2" colspan="1">Subject/implant characteristics</th>
<th valign="middle" align="center" rowspan="1" colspan="2">Toothbrush group</th>
</tr>
<tr>
<th valign="middle" align="center" rowspan="1" colspan="1">Manual</th>
<th valign="middle" align="center" rowspan="1" colspan="1">Powered</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Gender</td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Male</td>
<td valign="bottom" align="center" rowspan="1" colspan="1">11</td>
<td valign="bottom" align="center" rowspan="1" colspan="1">12</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Female</td>
<td valign="top" align="center" rowspan="1" colspan="1">9</td>
<td valign="top" align="center" rowspan="1" colspan="1">8</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Subtotal</td>
<td valign="top" align="center" rowspan="1" colspan="1">20</td>
<td valign="top" align="center" rowspan="1" colspan="1">20</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Age (year)</td>
<td valign="bottom" align="center" rowspan="1" colspan="1"></td>
<td valign="bottom" align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Mean (SD)</td>
<td valign="bottom" align="center" rowspan="1" colspan="1">54.5 (10.6)</td>
<td valign="bottom" align="center" rowspan="1" colspan="1">54.6 (11.7)</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Range</td>
<td valign="top" align="center" rowspan="1" colspan="1">39-75</td>
<td valign="top" align="center" rowspan="1" colspan="1">27-75</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Number of implants</td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Total (all subjects)</td>
<td valign="bottom" align="center" rowspan="1" colspan="1">33</td>
<td valign="bottom" align="center" rowspan="1" colspan="1">30</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Mean per subject (SD)</td>
<td valign="top" align="center" rowspan="1" colspan="1">1.65 (0.75)</td>
<td valign="top" align="center" rowspan="1" colspan="1">1.50 (0.76)</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Range</td>
<td valign="top" align="center" rowspan="1" colspan="1">1-4</td>
<td valign="top" align="center" rowspan="1" colspan="1">1-3</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Time since implant restoration (year)</td>
<td valign="bottom" align="center" rowspan="1" colspan="1"></td>
<td valign="bottom" align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Mean (SD)</td>
<td valign="bottom" align="center" rowspan="1" colspan="1">5.6 (2.8)</td>
<td valign="bottom" align="center" rowspan="1" colspan="1">4.8 (2.9)</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Range</td>
<td valign="top" align="center" rowspan="1" colspan="1">2.7-9.0</td>
<td valign="top" align="center" rowspan="1" colspan="1">3.2-8.1</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Time since implant placement (year)</td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Mean (SD)</td>
<td valign="bottom" align="center" rowspan="1" colspan="1">6.4 (3.1)</td>
<td valign="bottom" align="center" rowspan="1" colspan="1">6.2 (2.5)</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Range</td>
<td valign="top" align="center" rowspan="1" colspan="1">3.0-9.6</td>
<td valign="top" align="center" rowspan="1" colspan="1">3.6-8.7</td>
</tr>
</tbody>
</table>
</alternatives>
<table-wrap-foot>
<fn>
<p>SD: standard deviation.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="T2" orientation="portrait" position="float">
<label>Table 2</label>
<caption>
<title>Oral hygiene habits and compliance at baseline, one month, and two months.</title>
</caption>
<alternatives>
<graphic xlink:href="jpis-45-56-i002"></graphic>
<table frame="hsides" rules="rows">
<thead>
<tr>
<th valign="middle" align="left" rowspan="2" colspan="1">Oral hygiene habit</th>
<th valign="middle" align="center" rowspan="1" colspan="3">Manual tooth brush</th>
<th valign="middle" align="center" rowspan="1" colspan="3">Powered tooth brush</th>
</tr>
<tr>
<th valign="middle" align="center" rowspan="1" colspan="1">Baseline</th>
<th valign="middle" align="center" rowspan="1" colspan="1">1 month</th>
<th valign="middle" align="center" rowspan="1" colspan="1">2 months</th>
<th valign="middle" align="center" rowspan="1" colspan="1">Baseline</th>
<th valign="middle" align="center" rowspan="1" colspan="1">1 month</th>
<th valign="middle" align="center" rowspan="1" colspan="1">2 months</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Frequency of brushing per day</td>
<td valign="top" align="center" rowspan="1" colspan="1">2.33 (0.56)</td>
<td valign="top" align="center" rowspan="1" colspan="1">2.58 (0.50)</td>
<td valign="top" align="center" rowspan="1" colspan="1">2.50 (0.51)</td>
<td valign="top" align="center" rowspan="1" colspan="1">2.36 (0.49)</td>
<td valign="top" align="center" rowspan="1" colspan="1">2.16 (0.37)
<sup>a)</sup>
</td>
<td valign="top" align="center" rowspan="1" colspan="1">2.20 (0.41)
<sup>a)</sup>
</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Time of brushing (minute)</td>
<td valign="top" align="center" rowspan="1" colspan="1">1.85 (0.73)</td>
<td valign="top" align="center" rowspan="1" colspan="1">2.27 (0.57)</td>
<td valign="top" align="center" rowspan="1" colspan="1">2.41 (0.52)</td>
<td valign="top" align="center" rowspan="1" colspan="1">2.02 (0.80)</td>
<td valign="top" align="center" rowspan="1" colspan="1">3.00 (0.58)
<sup>a)</sup>
</td>
<td valign="top" align="center" rowspan="1" colspan="1">2.82 (0.48)
<sup>a)</sup>
</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Use of interdental brush (%)</td>
<td valign="top" align="center" rowspan="1" colspan="1">63</td>
<td valign="top" align="center" rowspan="1" colspan="1">67</td>
<td valign="top" align="center" rowspan="1" colspan="1">63</td>
<td valign="top" align="center" rowspan="1" colspan="1">56</td>
<td valign="top" align="center" rowspan="1" colspan="1">40</td>
<td valign="top" align="center" rowspan="1" colspan="1">48</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Use of dental floss (%)</td>
<td valign="top" align="center" rowspan="1" colspan="1">29</td>
<td valign="top" align="center" rowspan="1" colspan="1">40</td>
<td valign="top" align="center" rowspan="1" colspan="1">54</td>
<td valign="top" align="center" rowspan="1" colspan="1">24</td>
<td valign="top" align="center" rowspan="1" colspan="1">24</td>
<td valign="top" align="center" rowspan="1" colspan="1">24</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Use of water irrigation device (%)</td>
<td valign="top" align="center" rowspan="1" colspan="1">0</td>
<td valign="top" align="center" rowspan="1" colspan="1">0</td>
<td valign="top" align="center" rowspan="1" colspan="1">0</td>
<td valign="top" align="center" rowspan="1" colspan="1">0</td>
<td valign="top" align="center" rowspan="1" colspan="1">0</td>
<td valign="top" align="center" rowspan="1" colspan="1">0</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Use of toothpicks (%)</td>
<td valign="top" align="center" rowspan="1" colspan="1">8</td>
<td valign="top" align="center" rowspan="1" colspan="1">0</td>
<td valign="top" align="center" rowspan="1" colspan="1">0</td>
<td valign="top" align="center" rowspan="1" colspan="1">8</td>
<td valign="top" align="center" rowspan="1" colspan="1">4</td>
<td valign="top" align="center" rowspan="1" colspan="1">4</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Use of mouthwash (%)</td>
<td valign="top" align="center" rowspan="1" colspan="1">13</td>
<td valign="top" align="center" rowspan="1" colspan="1">13</td>
<td valign="top" align="center" rowspan="1" colspan="1">8</td>
<td valign="top" align="center" rowspan="1" colspan="1">24</td>
<td valign="top" align="center" rowspan="1" colspan="1">12</td>
<td valign="top" align="center" rowspan="1" colspan="1">12</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">Patient compliance for tooth brushing (%)</td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1">95.2 (4.6)</td>
<td valign="top" align="center" rowspan="1" colspan="1">96.1 (6.1)</td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1">98.7 (3.5)
<sup>a)</sup>
</td>
<td valign="top" align="center" rowspan="1" colspan="1">99.5 (1.1)</td>
</tr>
</tbody>
</table>
</alternatives>
<table-wrap-foot>
<fn>
<p>
<sup>a)</sup>
Statistically significant compared to the manual toothbrush group at the same time.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="T3" orientation="portrait" position="float">
<label>Table 3</label>
<caption>
<title>Reduction in clinical parameters between baseline and post-baseline follow-up points.</title>
</caption>
<alternatives>
<graphic xlink:href="jpis-45-56-i003"></graphic>
<table frame="hsides" rules="rows">
<thead>
<tr>
<th valign="middle" align="left" rowspan="2" colspan="1">Clinical parameters</th>
<th valign="middle" align="center" rowspan="1" colspan="2">Base to 1 month</th>
<th valign="middle" align="center" rowspan="1" colspan="2">1 month to 2 months</th>
<th valign="middle" align="center" rowspan="1" colspan="2">Base to 2 months</th>
</tr>
<tr>
<th valign="middle" align="center" rowspan="1" colspan="1">Mean ± SD</th>
<th valign="middle" align="center" rowspan="1" colspan="1">
<italic>P</italic>
-value
<sup>b)</sup>
</th>
<th valign="middle" align="center" rowspan="1" colspan="1">Mean ± SD</th>
<th valign="middle" align="center" rowspan="1" colspan="1">
<italic>P</italic>
-value
<sup>b)</sup>
</th>
<th valign="middle" align="center" rowspan="1" colspan="1">Mean ± SD</th>
<th valign="middle" align="center" rowspan="1" colspan="1">
<italic>P</italic>
-value
<sup>b)</sup>
</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">mPI</td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
<td valign="top" align="right" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
<td valign="top" align="right" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
<td valign="top" align="right" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Manual</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.67 ± 0.85</td>
<td valign="top" align="right" rowspan="1" colspan="1">< 0.001</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.09 ± 0.68</td>
<td valign="top" align="right" rowspan="1" colspan="1">0.439</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.76 ± 0.90</td>
<td valign="top" align="right" rowspan="1" colspan="1">< 0.001</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Powered</td>
<td valign="top" align="center" rowspan="1" colspan="1">1.07 ± 0.91</td>
<td valign="top" align="right" rowspan="1" colspan="1">0.001</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.20 ± 0.71</td>
<td valign="top" align="right" rowspan="1" colspan="1">0.134</td>
<td valign="top" align="center" rowspan="1" colspan="1">1.27 ± 0.87</td>
<td valign="top" align="right" rowspan="1" colspan="1">< 0.001</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">
<italic>P</italic>
-value
<sup>a)</sup>
</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.104</td>
<td valign="top" align="right" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1">0.499</td>
<td valign="top" align="right" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1">0.043</td>
<td valign="top" align="right" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">mSBI</td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
<td valign="top" align="right" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
<td valign="top" align="right" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1"></td>
<td valign="top" align="right" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Manual</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.48 ± 0.91</td>
<td valign="top" align="right" rowspan="1" colspan="1">0.006</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.09 ± 0.77</td>
<td valign="top" align="right" rowspan="1" colspan="1">0.491</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.58 ± 0.79</td>
<td valign="top" align="right" rowspan="1" colspan="1">0.001</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1"> Powered</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.63 ± 0.61</td>
<td valign="top" align="right" rowspan="1" colspan="1">< 0.001</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.30 ± 0.60</td>
<td valign="top" align="right" rowspan="1" colspan="1">0.013</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.93 ± 0.87</td>
<td valign="top" align="right" rowspan="1" colspan="1">< 0.001</td>
</tr>
<tr>
<td valign="top" align="left" rowspan="1" colspan="1">
<italic>P</italic>
-value
<sup>a)</sup>
</td>
<td valign="top" align="center" rowspan="1" colspan="1">0.300</td>
<td valign="top" align="right" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1">0.242</td>
<td valign="top" align="right" rowspan="1" colspan="1"></td>
<td valign="top" align="center" rowspan="1" colspan="1">0.100</td>
<td valign="top" align="right" rowspan="1" colspan="1"></td>
</tr>
</tbody>
</table>
</alternatives>
<table-wrap-foot>
<fn>
<p>
<sup>a)</sup>
Mann-Whitney test, used for comparison between the groups.</p>
<p>
<sup>b)</sup>
Wilcoxon signed rank test, used for comparison within the groups.</p>
<p>mPI: modified plaque index, mSBI: modified sulcus bleeding index, SD: standard deviation.</p>
</fn>
</table-wrap-foot>
</table-wrap>
</floats-group>
</pmc>
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