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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Accuracy of Linear Measurements Using Cone Beam Computed Tomography in Comparison with Clinical Measurements</title><author><name sortKey="Rokn, Amir Reza" sort="Rokn, Amir Reza" uniqKey="Rokn A" first="Amir Reza" last="Rokn">Amir Reza Rokn</name><affiliation><nlm:aff id="AFF1">Professor, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Periodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Hashemi, Kazem" sort="Hashemi, Kazem" uniqKey="Hashemi K" first="Kazem" last="Hashemi">Kazem Hashemi</name><affiliation><nlm:aff id="AFF2">Postdocs Student, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Akbari, Solmaz" sort="Akbari, Solmaz" uniqKey="Akbari S" first="Solmaz" last="Akbari">Solmaz Akbari</name><affiliation><nlm:aff id="AFF3">Assistant Professor, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Periodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Kharazifard, Mohammad Javad" sort="Kharazifard, Mohammad Javad" uniqKey="Kharazifard M" first="Mohammad Javad" last="Kharazifard">Mohammad Javad Kharazifard</name><affiliation><nlm:aff id="AFF4">Epidemiologist, Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Barikani, Hamidreza" sort="Barikani, Hamidreza" uniqKey="Barikani H" first="Hamidreza" last="Barikani">Hamidreza Barikani</name><affiliation><nlm:aff id="AFF5">Researcher, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Panjnoosh, Mehrdad" sort="Panjnoosh, Mehrdad" uniqKey="Panjnoosh M" first="Mehrdad" last="Panjnoosh">Mehrdad Panjnoosh</name><affiliation><nlm:aff id="AFF6">Assistant Professor, Head of Department of Oral and Maxillofacial Radiology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28127327</idno><idno type="pmc">5250631</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250631</idno><idno type="RBID">PMC:5250631</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">003069</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003069</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Accuracy of Linear Measurements Using Cone Beam Computed Tomography in Comparison with Clinical Measurements</title><author><name sortKey="Rokn, Amir Reza" sort="Rokn, Amir Reza" uniqKey="Rokn A" first="Amir Reza" last="Rokn">Amir Reza Rokn</name><affiliation><nlm:aff id="AFF1">Professor, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Periodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Hashemi, Kazem" sort="Hashemi, Kazem" uniqKey="Hashemi K" first="Kazem" last="Hashemi">Kazem Hashemi</name><affiliation><nlm:aff id="AFF2">Postdocs Student, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Akbari, Solmaz" sort="Akbari, Solmaz" uniqKey="Akbari S" first="Solmaz" last="Akbari">Solmaz Akbari</name><affiliation><nlm:aff id="AFF3">Assistant Professor, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Periodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Kharazifard, Mohammad Javad" sort="Kharazifard, Mohammad Javad" uniqKey="Kharazifard M" first="Mohammad Javad" last="Kharazifard">Mohammad Javad Kharazifard</name><affiliation><nlm:aff id="AFF4">Epidemiologist, Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Barikani, Hamidreza" sort="Barikani, Hamidreza" uniqKey="Barikani H" first="Hamidreza" last="Barikani">Hamidreza Barikani</name><affiliation><nlm:aff id="AFF5">Researcher, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Panjnoosh, Mehrdad" sort="Panjnoosh, Mehrdad" uniqKey="Panjnoosh M" first="Mehrdad" last="Panjnoosh">Mehrdad Panjnoosh</name><affiliation><nlm:aff id="AFF6">Assistant Professor, Head of Department of Oral and Maxillofacial Radiology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author></analytic><series><title level="j">Journal of Dentistry (Tehran, Iran)</title><idno type="ISSN">1735-2150</idno><idno type="eISSN">2008-2185</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objectives:</title><p>This study sought to evaluate the accuracy and errors of linear measurements of mesiodistal dimensions of Kennedy Class III edentulous space using cone beam computed tomography (CBCT) in comparison with clinical measurements.</p></sec><sec><title>Materials and Methods:</title><p>Nineteen Kennedy Class III dental arches were evaluated. An impression was made of each dental arch and poured with dental stone. The distance was measured on dental cast using a digital Vernier caliper with an accuracy of 0.1mm and on CBCT scans. Finally, the linear mesiodistal measurements were compared and the accuracy of CBCT technique was evaluated by calculating absolute value of errors, intra-class correlation coefficient and simple linear regression model.</p></sec><sec><title>Results:</title><p>In comparison with the cast method, estimation of size on CBCT scans had an error of −8.46% (underestimation) to 5.21% (overestimation). In 26.5% of the cases, an accepted error of ±1% was found. The absolute value of errors was found to be in the range of 0.21–8.46mm with an average value of 2.86 ±2.30mm.</p></sec><sec><title>Conclusions:</title><p>Although the measurements revealed statistically significant differences, this does not indicate a lower accuracy for the CBCT technique. In fact, CBCT can provide some information as a paraclinical tool and the clinician can combine these data with clinical data and achieve greater accuracy. Undoubtedly, calibration of data collected by clinical and paraclinical techniques and the clinician’s expertise in use of CBCT software programs can increase the accuracy of implant placement.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Sato, S" uniqKey="Sato S">S Sato</name></author><author><name sortKey="Arai, Y" uniqKey="Arai Y">Y Arai</name></author><author><name sortKey="Shinoda, K" uniqKey="Shinoda K">K Shinoda</name></author><author><name sortKey="Ito, K" uniqKey="Ito K">K. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">J Dent (Tehran)</journal-id><journal-id journal-id-type="iso-abbrev">J Dent (Tehran)</journal-id><journal-id journal-id-type="publisher-id">JOD</journal-id><journal-id journal-id-type="pmc">JOD</journal-id><journal-title-group><journal-title>Journal of Dentistry (Tehran, Iran)</journal-title></journal-title-group><issn pub-type="ppub">1735-2150</issn><issn pub-type="epub">2008-2185</issn><publisher><publisher-name>Tehran University of Medical Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">28127327</article-id><article-id pub-id-type="pmc">5250631</article-id><article-id pub-id-type="publisher-id">jod-13-333</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>Accuracy of Linear Measurements Using Cone Beam Computed Tomography in Comparison with Clinical Measurements</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Rokn</surname><given-names>Amir Reza</given-names></name><xref ref-type="aff" rid="AFF1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Hashemi</surname><given-names>Kazem</given-names></name><xref ref-type="aff" rid="AFF2"><sup>2</sup></xref><xref ref-type="corresp" rid="C1"><sup>*</sup></xref></contrib><contrib contrib-type="author"><name><surname>Akbari</surname><given-names>Solmaz</given-names></name><xref ref-type="aff" rid="AFF3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Kharazifard</surname><given-names>Mohammad Javad</given-names></name><xref ref-type="aff" rid="AFF4"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Barikani</surname><given-names>Hamidreza</given-names></name><xref ref-type="aff" rid="AFF5"><sup>5</sup></xref></contrib><contrib contrib-type="author"><name><surname>Panjnoosh</surname><given-names>Mehrdad</given-names></name><xref ref-type="aff" rid="AFF6"><sup>6</sup></xref></contrib><aff id="AFF1"><label>1</label>Professor, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Periodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran</aff><aff id="AFF2"><label>2</label>Postdocs Student, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran</aff><aff id="AFF3"><label>3</label>Assistant Professor, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Periodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran</aff><aff id="AFF4"><label>4</label>Epidemiologist, Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran</aff><aff id="AFF5"><label>5</label>Researcher, Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran</aff><aff id="AFF6"><label>6</label>Assistant Professor, Head of Department of Oral and Maxillofacial Radiology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran</aff></contrib-group><author-notes><corresp id="C1"><label>*</label>Corresponding author: K. Hashemi, Dental Implant Research Center, Dental School Tehran University of Medical Sciences, Tehran, Iran,<email>kazemhashemi45@gmail.com</email></corresp></author-notes><pub-date pub-type="ppub"><month>9</month><year>2016</year></pub-date><volume>13</volume><issue>5</issue><fpage>333</fpage><lpage>339</lpage><history><date date-type="received"><day>02</day><month>2</month><year>2016</year></date><date date-type="accepted"><day>26</day><month>6</month><year>2016</year></date></history><permissions><copyright-statement>Copyright© Dental Research Center, Tehran University of Medical Sciences</copyright-statement><copyright-year>2016</copyright-year><license><license-p>This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.</license-p></license></permissions><abstract><sec><title>Objectives:</title><p>This study sought to evaluate the accuracy and errors of linear measurements of mesiodistal dimensions of Kennedy Class III edentulous space using cone beam computed tomography (CBCT) in comparison with clinical measurements.</p></sec><sec><title>Materials and Methods:</title><p>Nineteen Kennedy Class III dental arches were evaluated. An impression was made of each dental arch and poured with dental stone. The distance was measured on dental cast using a digital Vernier caliper with an accuracy of 0.1mm and on CBCT scans. Finally, the linear mesiodistal measurements were compared and the accuracy of CBCT technique was evaluated by calculating absolute value of errors, intra-class correlation coefficient and simple linear regression model.</p></sec><sec><title>Results:</title><p>In comparison with the cast method, estimation of size on CBCT scans had an error of −8.46% (underestimation) to 5.21% (overestimation). In 26.5% of the cases, an accepted error of ±1% was found. The absolute value of errors was found to be in the range of 0.21–8.46mm with an average value of 2.86 ±2.30mm.</p></sec><sec><title>Conclusions:</title><p>Although the measurements revealed statistically significant differences, this does not indicate a lower accuracy for the CBCT technique. In fact, CBCT can provide some information as a paraclinical tool and the clinician can combine these data with clinical data and achieve greater accuracy. Undoubtedly, calibration of data collected by clinical and paraclinical techniques and the clinician’s expertise in use of CBCT software programs can increase the accuracy of implant placement.</p></sec></abstract><kwd-group><kwd>Cone-Beam Computed Tomography</kwd><kwd>Dental Arch</kwd><kwd>Dimensional Measurement Accuracy</kwd></kwd-group></article-meta></front><body><sec sec-type="intro"><title>INTRODUCTION</title><p>Adjunct techniques are necessary to evaluate the quality and quantity of bone so that a proper treatment plan can be offered for implant placement [<xref rid="B1" ref-type="bibr">1</xref>,<xref rid="B2" ref-type="bibr">2</xref>]. Panoramic X-ray units have an inherent distortion, which is influenced by some factors; for example, a change in the patient’s head position results in measurement errors [<xref rid="B3" ref-type="bibr">3</xref>]. Apart from distortion, magnification of panoramic radiographs may result in a change in treatment plan [<xref rid="B4" ref-type="bibr">4</xref>,<xref rid="B5" ref-type="bibr">5</xref>]. On the other hand, computed tomography (CT) has lower accuracy compared to cone beam computed tomography (CBCT) [<xref rid="B3" ref-type="bibr">3</xref>,<xref rid="B6" ref-type="bibr">6</xref>]; CBCT images have characteristics such as accuracy and clarity [<xref rid="B7" ref-type="bibr">7</xref>]. The first CBCT scanners were introduced almost three decades ago [<xref rid="B8" ref-type="bibr">8</xref>]; CBCT was first introduced in 1982 for angiography procedures [<xref rid="B9" ref-type="bibr">9</xref>]. Its first application in dentistry occurred in 2000 in Loma Linda University [<xref rid="B10" ref-type="bibr">10</xref>]. Evaluation of alveolar bone is very important for dental implant treatment planning [<xref rid="B1" ref-type="bibr">1</xref>–<xref rid="B3" ref-type="bibr">3</xref>]. The CT scan technique has been reported to be the best preoperative technique for evaluation of three-dimensional morphology and measurements [<xref rid="B1" ref-type="bibr">1</xref>–<xref rid="B3" ref-type="bibr">3</xref>]. Many studies have reported that panoramic radiography is a reliable technique for evaluation of bone height [<xref rid="B11" ref-type="bibr">11</xref>,<xref rid="B12" ref-type="bibr">12</xref>]. To achieve optimal functional and esthetic results, dental implant should be placed accurately in the desired area [<xref rid="B13" ref-type="bibr">13</xref>]. Existing technologies such as CBCT, in conjunction with virtual three-dimensional reconstruction of implant placement and fabrication of surgical templates with stereolithography are used in both treatment planning and implant placement. However, the accuracy of CBCT technique is unknown [<xref rid="B13" ref-type="bibr">13</xref>] and even with the use of this system, errors of 1.5mm and 1mm have been reported in horizontal and vertical dimensions [<xref rid="B14" ref-type="bibr">14</xref>,<xref rid="B15" ref-type="bibr">15</xref>]. Errors of 0.65–1.78mm have been reported for the CBCT technique. The advantages of CBCT include high resolution, lower cost, lower radiation dose, rapid scanning, easy handling and availability in comparison with the CT technique [<xref rid="B16" ref-type="bibr">16</xref>,<xref rid="B17" ref-type="bibr">17</xref>]. Different CBCT machines have differences in their exposure parameters including voltage, tube current, exposure, field of view and extent of gantry rotation around the patient’s head, resulting in differences in absorbed radiation dose and the quality of images produced [<xref rid="B18" ref-type="bibr">18</xref>,<xref rid="B19" ref-type="bibr">19</xref>].</p><p>The aim of the present study was to evaluate the accuracy of mesiodistal linear measurements made using CBCT technique in the edentulous space in rehabilitation treatments using dental implants.</p></sec><sec sec-type="materials|methods"><title>MATERIALS AND METHODS</title><p>The samples consisted of 18 patients and 19 casts with Kennedy Class III edentulous space with at least two lost teeth; two edentulous areas were evaluated in one patient and the respective casts. The sample size was determined based on a pilot study with five samples. The patients were selected among those referring to the Department of Implantology, School of Dentistry, Tehran University of Medical Sciences. This study was approved by the Ethics Committee of Tehran University of Medical Sciences (Code number: 14701).</p><p>An impression was taken from the edentulous area using polyether impression material due to its high accuracy and low volumetric change. The impressions were poured with dental stone due to its high resistance and low volumetric change, according to manufacturer’s instructtions. Then, the patients were referred to the Department of Radiology to take CBCT scans of the edentulous area. The CBCT scans were taken using a volumetric tomography machine (Promax 3D; Planmeca, Helsinki, Finland). An important consideration is the fact that evaluation of the edentulous space of one lost tooth from a clinical and practical point of view and its relationship with the accuracy of CBCT might not be statistically significant due to the short span of the edentulous space or in other words due to the small width of the tooth lost; therefore, the space created by the loss of two teeth was evaluated in the present study. Age and sex are not important in such evaluations and measurements because the aim of such studies is to measure the linear distance between two teeth using two different techniques and compare the obtained results. The buccolingual or buccopalatal center of the stone cast was determined by the clinician using welding wire with proper flexion properties. The wire was adapted to the buccolingual center and measured with a digital Vernier caliper with an accuracy of 0.1mm. It was straight in some cases and curved in some others. On the other hand, the same distance was measured on CBCT scans by a radiologist using the relevant software program with 0.1mm accuracy. Since no similar study was available, a pilot study was carried out on five samples to calculate the sample size. The mean and standard deviation of linear measurements made on CBCT scans and by the clinical technique were calculated. The mean difference in measurements made on the cast and on CBCT scans in the pilot study was 1.7mm with a variance of approximately 1mm. Therefore, at a confidence interval of 0.99 and test power of 0.99, the number of samples was found to be 10.</p><sec sec-type="methods"><title>Statistical analysis:</title><p>Crude value of error was obtained from the difference between the values measured on CBCT scans and dental casts. Also, absolute crude value was considered as absolute value of error. Intraclass correlation coefficient and simple linear regression model were used to determine the mean of measurements and estimate the true values from data obtained by the CBCT method, respectively.</p></sec></sec><sec sec-type="results"><title>RESULTS</title><p>The samples consisted of 19 casts; of which, 12 casts (63.2%) were maxillary and seven casts (36.8%) were mandibular. Of all the casts, eight casts (42.1%) had edentulous spaces of two teeth, seven casts (36.8%) had edentulous spaces of three teeth, three casts (15.8%) had edentulous spaces of four teeth and one cast (5.3%) had an edentulous space of five teeth. In comparison with the cast method, estimation of size using CBCT method had an error of −8.46% (underestimation) to 5.21% (overestimation). For 26.5 % of cases, an accepted error of ±1% was found. Also, in straight (versus curved) cases, an error range of −8.29% (underestimation) to 5.21% (overestimation) was observed.</p><p>Furthermore, an accepted error of ±1% was observed for 15.9% of cases. In this study, the absolute value of errors was found to be in the range of 0.21–8.46mm with an average value of 2.86 ±2.30mm. Also, the value of error was 3.74 ±0.03mm for curved cases. In the straight cases, an absolute error range of 0.34 to 8.29mm with an average of 2.64 ±2.07mm was obtained (<xref ref-type="fig" rid="F1">Figs. 1</xref> and <xref ref-type="fig" rid="F2">2</xref>). The intraclass correlation coefficient value was 0.804 and 0.730, respectively for the agreement between CBCT measurements and the values for straight and curved cases. These findings showed higher agreement between CBCT measurements and values measured on dental casts for straight cases (P<0.001).</p><fig id="F1" orientation="portrait" position="float"><label>Fig. 1:</label><caption><p>The histogram of the differences between CBCT and cast measurements of curved lines (Dif.c)</p></caption><graphic xlink:href="JOD-13-333-g001"></graphic></fig><fig id="F2" orientation="portrait" position="float"><label>Fig. 2:</label><caption><p>The histogram of the differences between CBCT and cast measurements of straight lines (Dif.s)</p></caption><graphic xlink:href="JOD-13-333-g002"></graphic></fig><p>A linear regression equation of size on cast= size on CBCT scan ×0.74 +5.76 (R
<sup>2</sup>=0.53) was obtained for the best estimation of true size from the size measured on CBCT scans (P<0.001).</p></sec><sec sec-type="discussion"><title>DISCUSSION</title><p>In the present study, the accuracy of measuring the mesiodistal distance of edentulous spaces by CBCT technique was evaluated. Space management and force distribution on implants and decreasing the cantilever length are important major issues in treatment planning for dental implants. At present, CBCT is considered as a paraclinical tool to increase the accuracy and decrease the length of clinical procedures by eliminating the need for bone mapping, leading to a better treatment plan. A large number of studies have been carried out on the accuracy and validity of the measurements of vertical dimension and thickness of bone [<xref rid="B1" ref-type="bibr">1</xref>,<xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B20" ref-type="bibr">20</xref>]. To the best of our knowledge, no data were brought up in relation to the accuracy of CBCT for mesiodistal or horizontal dimensional measurements. The majority of measurements relate to orthodontic landmarks, i.e. the majority of studies have used full CBCT or ortho-facial systems and conventional dental radiography has been used less frequently.</p><p>Undoubtedly, in such studies, it is advisable to use anthropometric characteristics. The advantage of the present study was that it allowed an indirect anthropometric assessment. As explained in the “results” section, there were significant differences in measurements made between the two techniques, which were consistent with the results of some previous studies [<xref rid="B1" ref-type="bibr">1</xref>,<xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B20" ref-type="bibr">20</xref>]. What is important in the accuracy of linear measurements in implant treatments, as shown in previous studies [<xref rid="B1" ref-type="bibr">1</xref>,<xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B20" ref-type="bibr">20</xref>], is that the differences between CBCT measurements or other radiographic techniques such as CT and clinical measurements might be statistically significant but clinically and practically acceptable, which means they might not be clinically important [<xref rid="B1" ref-type="bibr">1</xref>,<xref rid="B5" ref-type="bibr">5</xref>]. Therefore, calibration method of such studies is very important. Lascala et al. [<xref rid="B20" ref-type="bibr">20</xref>] carried out a study on 13 measurements in eight skulls; an important finding was the fact that actual measurements were greater than CBCT measurements, with significant differences. Such results were expected because NewTom 9000 CBCT unit was used, which is specifically used for dentomaxillofacial imaging. In studies on horizontal distances, the extent of the area is very important and small or medium-sized areas exhibit differences from larger areas. An important consideration in such studies is lack of sensitivity to detect small differences in accuracy. In fact, statistical criteria affect the evaluations, and even the results achieved by different CBCT units might be different due to differences in software and hardware capabilities [<xref rid="B6" ref-type="bibr">6</xref>,<xref rid="B20" ref-type="bibr">20</xref>]. Another important consideration in studies on the accuracy of CBCT is the method error, which reflects the limitations of CBCT and the software programs used. In three-dimensional images, the method error depends on factors such as resolution (voxel size) and the size of the landmarks in question. It should be noted that the radiolucency of the markers measured increases error [<xref rid="B21" ref-type="bibr">21</xref>,<xref rid="B22" ref-type="bibr">22</xref>].</p><p>A change in skull orientation does not influence the accuracy of linear measurements [<xref rid="B1" ref-type="bibr">1</xref>]; however, the results of a study in 2013 showed that a change in position during acquisition might result in changes in width and height, especially in the upper jaw and particularly in molar and premolar areas [<xref rid="B3" ref-type="bibr">3</xref>]. In addition, the operator’s experience affects the accuracy [<xref rid="B21" ref-type="bibr">21</xref>]; although another study showed that high reliability can be achieved without formal software training [<xref rid="B22" ref-type="bibr">22</xref>].</p><p>Based on the above discussion, CBCT is still the best tool for preoperative assessment for rehabilitative treatments with dental implants and it can provide three-dimensional images of the mineralized tissue with minimum distortion [<xref rid="B23" ref-type="bibr">23</xref>,<xref rid="B24" ref-type="bibr">24</xref>]. In the current study, the majority of the evaluated edentulous spaces were in the upper jaw (12 spaces vs. seven spaces in the lower jaw). In the upper jaw, in five cases, the differences in measurements made on CBCT scans and on dental casts were more than 1mm; in three cases the measurements on casts were 1mm larger than those on CBCT scans and in four cases they were less than 1mm. In the lower jaw, the differences in three CBCT cases and in three cast cases were more than 1mm and in one case less than 1mm. These differences can be explained by considering the differences in the number of evaluated cases in the upper and lower jaws. No significant relationship was found between the size of the edentulous area and the differences between the two measurement techniques; however, the error level decreased with an increase in the number of lost teeth. However, the sample size should increase for more accurate evaluations. What should be taken into account in clinical evaluations is the fact that measurements are made on the most superficial layer of soft tissues, which affects the numerical values obtained because the amount of gingival recession after bone resorption or an increase in gingival volume, irrespective of the reason, affects the data collected. As mentioned previously, depending on the type of the CBCT unit used (i.e. detector type, which might be intensifier or flat panel), there will be some degrees of deformity. In the current study, a Planmeca CBCT unit, which was flat panel with high accuracy was used. However, what should be considered is the fact that all the CBCT measurements were made on the axial view of different sections, which might have affected the numerical data values. On the other hand, the area selected for the initiation (clicking point) of measurements is important in terms of corono-apical and buccolingual (or buccopalatal) height. The following conclusions can be drawn from the results of the present study:
<list list-type="simple"><list-item><p>- The clinician should be familiar with the CBCT principles and software programs and should properly use them.</p></list-item><list-item><p>- Clinical and radiographic evaluations should be calibrated with each other.</p></list-item><list-item><p>- What is important for the number of dental implants and their distribution is not solely the size of the arch involved; the shape of the arch, as well as the sizes and the diameters of the implants are also important [<xref rid="B25" ref-type="bibr">25</xref>].</p></list-item><list-item><p>- It should be emphasized that generally, paraclinical examinations are adjunctive tools and do not have an effective and accurate application alone in the clinical setting; but if acquisition protocols are followed precisely they will certainly be more reliable. What is important is the effect of artifacts on the CBT technique [<xref rid="B4" ref-type="bibr">4</xref>]. Therefore, depending on the involved area, the error level might be different. For example, the original value might be less than that measured on CBCT scans and the range of this increase might be 90–100% due to the higher density of obturated root canals, leading to artifacts and errors [<xref rid="B26" ref-type="bibr">26</xref>].</p></list-item></list></p><p>In general, CBCT provides some data for the clinician, which might be under the influence of the type of the section (oblique or vertical), the view in question (axial or panoramic) and buccolingual or occlusogingival direction. Finally, the clinician should use the data correctly. The results of this study showed that CBCT had lower error rate in measuring straight lines than curved lines.</p></sec><sec sec-type="conclusion"><title>CONCLUSION</title><p>Evaluation of the accuracy of CBCT technique by comparing the linear distance of the mesiodistal edentulous space between two teeth measured on the casts and on CBCT scans yielded the following results:
<list list-type="simple"><list-item><p>The CBCT unit used was highly accurate; however, its application in the clinical setting requires operator’s skills and his/her familiarity with CBCT software programs. Attention to the calibration of the data acquired by clinical examination and CBCT is very important.</p></list-item></list></p></sec></body><back><ref-list><title>REFERENCES</title><ref id="B1"><label>1-</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sato</surname><given-names>S</given-names></name><name><surname>Arai</surname><given-names>Y</given-names></name><name><surname>Shinoda</surname><given-names>K</given-names></name><name><surname>Ito</surname><given-names>K.</given-names></name></person-group><article-title>Clinical application of a new cone-beam computerized tomography system to assess multiple two-dimensional images for the preoperative treatment planning of maxillary implants: case reports</article-title>.
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