Oral health-related quality of life and prosthetic status of nursing home residents with or without dementia
Identifieur interne : 002B12 ( Pmc/Corpus ); précédent : 002B11; suivant : 002B13Oral health-related quality of life and prosthetic status of nursing home residents with or without dementia
Auteurs : Anna-Luisa Klotz ; Alexander Jochen Hassel ; Johannes Schröder ; Peter Rammelsberg ; Andreas ZenthöferSource :
- Clinical Interventions in Aging [ 1176-9092 ] ; 2017.
Abstract
The objective of this cross-sectional study was to evaluate the effect of prosthetic status on the oral health-related quality of life (OHRQoL) of nursing home residents with or without dementia.
The study was performed in 14 nursing homes across the federal state of Baden-Württemberg, Germany. All eligible participants were included, and general and medical information and information about their dental and prosthetic statuses were collected. The Geriatric Oral Health Assessment Index (GOHAI) was administered to evaluate OHRQoL. The Mini-Mental State Examination (MMSE) served to classify participants into living or not living with dementia according to the established cutoff value for dementia (MMSE <24). Parametric bivariate statistics and logistic regression models were used to analyze data at
A total of 169 participants were included in this study. The mean age of the participants was 82.9 years. A total of some 70% of the sample was living with dementia. The mean GOHAI score along the sample was 49.1 (8.3), and 41% of the sample reported substantially compromised OHRQoL (GOHAI <50). OHRQoL was statistically similar for people with or without dementia (
The OHRQoL of elderly nursing home residents is substantially compromised. Several prosthetic treatment needs for residents living with or without dementia were identified. Edentulism without tooth replacement and having <5 teeth resulted in an increased risk of substantially compromised OHRQoL. Further studies should be conducted to determine whether improvements in prosthetic status can increase OHRQoL.
Url:
DOI: 10.2147/CIA.S125128
PubMed: 28442895
PubMed Central: 5396830
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PMC:5396830Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Oral health-related quality of life and prosthetic status of nursing home residents with or without dementia</title><author><name sortKey="Klotz, Anna Luisa" sort="Klotz, Anna Luisa" uniqKey="Klotz A" first="Anna-Luisa" last="Klotz">Anna-Luisa Klotz</name><affiliation><nlm:aff id="af1-cia-12-659">Department of Prosthodontics, Dental School</nlm:aff></affiliation></author><author><name sortKey="Hassel, Alexander Jochen" sort="Hassel, Alexander Jochen" uniqKey="Hassel A" first="Alexander Jochen" last="Hassel">Alexander Jochen Hassel</name><affiliation><nlm:aff id="af1-cia-12-659">Department of Prosthodontics, Dental School</nlm:aff></affiliation></author><author><name sortKey="Schroder, Johannes" sort="Schroder, Johannes" uniqKey="Schroder J" first="Johannes" last="Schröder">Johannes Schröder</name><affiliation><nlm:aff id="af2-cia-12-659">Institute of Gerontology</nlm:aff></affiliation><affiliation><nlm:aff id="af3-cia-12-659">Section of Geriatric Psychiatry, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Rammelsberg, Peter" sort="Rammelsberg, Peter" uniqKey="Rammelsberg P" first="Peter" last="Rammelsberg">Peter Rammelsberg</name><affiliation><nlm:aff id="af1-cia-12-659">Department of Prosthodontics, Dental School</nlm:aff></affiliation></author><author><name sortKey="Zenthofer, Andreas" sort="Zenthofer, Andreas" uniqKey="Zenthofer A" first="Andreas" last="Zenthöfer">Andreas Zenthöfer</name><affiliation><nlm:aff id="af1-cia-12-659">Department of Prosthodontics, Dental School</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28442895</idno><idno type="pmc">5396830</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396830</idno><idno type="RBID">PMC:5396830</idno><idno type="doi">10.2147/CIA.S125128</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">002B12</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002B12</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Oral health-related quality of life and prosthetic status of nursing home residents with or without dementia</title><author><name sortKey="Klotz, Anna Luisa" sort="Klotz, Anna Luisa" uniqKey="Klotz A" first="Anna-Luisa" last="Klotz">Anna-Luisa Klotz</name><affiliation><nlm:aff id="af1-cia-12-659">Department of Prosthodontics, Dental School</nlm:aff></affiliation></author><author><name sortKey="Hassel, Alexander Jochen" sort="Hassel, Alexander Jochen" uniqKey="Hassel A" first="Alexander Jochen" last="Hassel">Alexander Jochen Hassel</name><affiliation><nlm:aff id="af1-cia-12-659">Department of Prosthodontics, Dental School</nlm:aff></affiliation></author><author><name sortKey="Schroder, Johannes" sort="Schroder, Johannes" uniqKey="Schroder J" first="Johannes" last="Schröder">Johannes Schröder</name><affiliation><nlm:aff id="af2-cia-12-659">Institute of Gerontology</nlm:aff></affiliation><affiliation><nlm:aff id="af3-cia-12-659">Section of Geriatric Psychiatry, University of Heidelberg, Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Rammelsberg, Peter" sort="Rammelsberg, Peter" uniqKey="Rammelsberg P" first="Peter" last="Rammelsberg">Peter Rammelsberg</name><affiliation><nlm:aff id="af1-cia-12-659">Department of Prosthodontics, Dental School</nlm:aff></affiliation></author><author><name sortKey="Zenthofer, Andreas" sort="Zenthofer, Andreas" uniqKey="Zenthofer A" first="Andreas" last="Zenthöfer">Andreas Zenthöfer</name><affiliation><nlm:aff id="af1-cia-12-659">Department of Prosthodontics, Dental School</nlm:aff></affiliation></author></analytic><series><title level="j">Clinical Interventions in Aging</title><idno type="ISSN">1176-9092</idno><idno type="eISSN">1178-1998</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Purpose</title><p>The objective of this cross-sectional study was to evaluate the effect of prosthetic status on the oral health-related quality of life (OHRQoL) of nursing home residents with or without dementia.</p></sec><sec><title>Methods</title><p>The study was performed in 14 nursing homes across the federal state of Baden-Württemberg, Germany. All eligible participants were included, and general and medical information and information about their dental and prosthetic statuses were collected. The Geriatric Oral Health Assessment Index (GOHAI) was administered to evaluate OHRQoL. The Mini-Mental State Examination (MMSE) served to classify participants into living or not living with dementia according to the established cutoff value for dementia (MMSE <24). Parametric bivariate statistics and logistic regression models were used to analyze data at <italic>P</italic><0.05.</p></sec><sec><title>Results</title><p>A total of 169 participants were included in this study. The mean age of the participants was 82.9 years. A total of some 70% of the sample was living with dementia. The mean GOHAI score along the sample was 49.1 (8.3), and 41% of the sample reported substantially compromised OHRQoL (GOHAI <50). OHRQoL was statistically similar for people with or without dementia (<italic>P</italic>=0.234); objective oral health was also similar in both groups (<italic>P</italic>>0.05). The number of teeth (odds ratio [OR]: 2.0), the type of prosthetic status (OR: 6.5), and denture-related treatment needs (OR: 2.4) were the major factors significantly affecting OHRQoL (<italic>P</italic><0.05).</p></sec><sec><title>Conclusion</title><p>The OHRQoL of elderly nursing home residents is substantially compromised. Several prosthetic treatment needs for residents living with or without dementia were identified. Edentulism without tooth replacement and having <5 teeth resulted in an increased risk of substantially compromised OHRQoL. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Interv Aging</journal-id><journal-id journal-id-type="iso-abbrev">Clin Interv Aging</journal-id><journal-id journal-id-type="publisher-id">Clinical Interventions in Aging</journal-id><journal-title-group><journal-title>Clinical Interventions in Aging</journal-title></journal-title-group><issn pub-type="ppub">1176-9092</issn><issn pub-type="epub">1178-1998</issn><publisher><publisher-name>Dove Medical Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">28442895</article-id><article-id pub-id-type="pmc">5396830</article-id><article-id pub-id-type="doi">10.2147/CIA.S125128</article-id><article-id pub-id-type="publisher-id">cia-12-659</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Research</subject></subj-group></article-categories><title-group><article-title>Oral health-related quality of life and prosthetic status of nursing home residents with or without dementia</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Klotz</surname><given-names>Anna-Luisa</given-names></name><xref ref-type="aff" rid="af1-cia-12-659">1</xref><xref ref-type="corresp" rid="c1-cia-12-659"></xref></contrib><contrib contrib-type="author"><name><surname>Hassel</surname><given-names>Alexander Jochen</given-names></name><xref ref-type="aff" rid="af1-cia-12-659">1</xref></contrib><contrib contrib-type="author"><name><surname>Schröder</surname><given-names>Johannes</given-names></name><xref ref-type="aff" rid="af2-cia-12-659">2</xref><xref ref-type="aff" rid="af3-cia-12-659">3</xref></contrib><contrib contrib-type="author"><name><surname>Rammelsberg</surname><given-names>Peter</given-names></name><xref ref-type="aff" rid="af1-cia-12-659">1</xref></contrib><contrib contrib-type="author"><name><surname>Zenthöfer</surname><given-names>Andreas</given-names></name><xref ref-type="aff" rid="af1-cia-12-659">1</xref></contrib></contrib-group><aff id="af1-cia-12-659"><label>1</label>Department of Prosthodontics, Dental School</aff><aff id="af2-cia-12-659"><label>2</label>Institute of Gerontology</aff><aff id="af3-cia-12-659"><label>3</label>Section of Geriatric Psychiatry, University of Heidelberg, Heidelberg, Germany</aff><author-notes><corresp id="c1-cia-12-659">Correspondence: Anna-Luisa Klotz, Department of Prosthodontics, Dental School, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany, Tel +49 6221 56 8799, Fax +49 6221 56 5371, Email <email>anna-luisa.klotz@med.uni-heidelberg.de</email></corresp></author-notes><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>11</day><month>4</month><year>2017</year></pub-date><volume>12</volume><fpage>659</fpage><lpage>665</lpage><permissions><copyright-statement>© 2017 Klotz et al. This work is published and licensed by Dove Medical Press Limited</copyright-statement><copyright-year>2017</copyright-year><license><license-p>The full terms of this license are available at <ext-link ext-link-type="uri" xlink:href="https://www.dovepress.com/terms.php">https://www.dovepress.com/terms.php</ext-link> and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">http://creativecommons.org/licenses/by-nc/3.0/</ext-link>). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.</license-p></license></permissions><abstract><sec><title>Purpose</title><p>The objective of this cross-sectional study was to evaluate the effect of prosthetic status on the oral health-related quality of life (OHRQoL) of nursing home residents with or without dementia.</p></sec><sec><title>Methods</title><p>The study was performed in 14 nursing homes across the federal state of Baden-Württemberg, Germany. All eligible participants were included, and general and medical information and information about their dental and prosthetic statuses were collected. The Geriatric Oral Health Assessment Index (GOHAI) was administered to evaluate OHRQoL. The Mini-Mental State Examination (MMSE) served to classify participants into living or not living with dementia according to the established cutoff value for dementia (MMSE <24). Parametric bivariate statistics and logistic regression models were used to analyze data at <italic>P</italic><0.05.</p></sec><sec><title>Results</title><p>A total of 169 participants were included in this study. The mean age of the participants was 82.9 years. A total of some 70% of the sample was living with dementia. The mean GOHAI score along the sample was 49.1 (8.3), and 41% of the sample reported substantially compromised OHRQoL (GOHAI <50). OHRQoL was statistically similar for people with or without dementia (<italic>P</italic>=0.234); objective oral health was also similar in both groups (<italic>P</italic>>0.05). The number of teeth (odds ratio [OR]: 2.0), the type of prosthetic status (OR: 6.5), and denture-related treatment needs (OR: 2.4) were the major factors significantly affecting OHRQoL (<italic>P</italic><0.05).</p></sec><sec><title>Conclusion</title><p>The OHRQoL of elderly nursing home residents is substantially compromised. Several prosthetic treatment needs for residents living with or without dementia were identified. Edentulism without tooth replacement and having <5 teeth resulted in an increased risk of substantially compromised OHRQoL. Further studies should be conducted to determine whether improvements in prosthetic status can increase OHRQoL.</p></sec></abstract><kwd-group><title>Keywords</title><kwd>nursing home</kwd><kwd>dementia</kwd><kwd>oral health-related quality of life</kwd><kwd>prosthetic condition</kwd></kwd-group></article-meta></front><body><sec sec-type="intro"><title>Introduction</title><p>Aging of the population is a long-term trend in all middle- and high-income countries. As a result, the total amount of care needed increases and many of those care dependent elderly are living in nursing homes.<xref rid="b1-cia-12-659" ref-type="bibr">1</xref>,<xref rid="b2-cia-12-659" ref-type="bibr">2</xref> Studies have consistently revealed poor oral hygiene and health among people living in nursing homes compared with younger and community-dwelling older adults. Nursing home residents face more severe oral problems, for example, tooth loss, periodontal disease, caries, and xerostomia.<xref rid="b1-cia-12-659" ref-type="bibr">1</xref>–<xref rid="b4-cia-12-659" ref-type="bibr">4</xref> Worsening of oral health not only affects chewing function, and therefore nutrition, but also general health by aggravating cardiovascular diseases and infectious respiratory diseases.<xref rid="b5-cia-12-659" ref-type="bibr">5</xref>–<xref rid="b8-cia-12-659" ref-type="bibr">8</xref> Most elderly people wear some sort of denture, increasingly frequently combined with natural teeth or implants needing adequate daily hygiene and dental aftercare.<xref rid="b9-cia-12-659" ref-type="bibr">9</xref> For nursing home residents, the following three major threats cause deteriorating oral conditions: first, carers frequently have limited knowledge of the specific oral care needed by the elderly and insufficient time to perform this properly; second, access to dental care providers is limited because of immobility; and, third, oral health issues are of low importance to the elderly themselves in the context of multimorbidity, including dementia.<xref rid="b3-cia-12-659" ref-type="bibr">3</xref>,<xref rid="b10-cia-12-659" ref-type="bibr">10</xref></p><p>The World Health Organization suggests, however, that health is defined not only by the absence of disease but also by subjective well-being (health-related quality of life). Oral health-related quality of life (OHRQoL) is one aspect of this.<xref rid="b11-cia-12-659" ref-type="bibr">11</xref> Instruments have been developed for the assessment of OHRQoL. Besides the Oral Health Impact Profile (OHIP), a popular means of evaluation of OHRQoL in many communities, the Geriatric Oral Health Assessment Index (GOHAI) has been described as a quick and valid tool enabling the detection of small changes in oral health among elderly populations.<xref rid="b12-cia-12-659" ref-type="bibr">12</xref>,<xref rid="b13-cia-12-659" ref-type="bibr">13</xref></p><p>Although OHRQoL is an important dental endpoint, the literature contains few reports of evaluation of dental and prosthetic factors affecting OHRQoL among the elderly. With regard to prosthetic factors, the number of teeth and the type of denture worn seem to be relevant to the OHRQoL of different community-dwelling populations.<xref rid="b14-cia-12-659" ref-type="bibr">14</xref>–<xref rid="b18-cia-12-659" ref-type="bibr">18</xref></p><p>Limited information is available about the OHRQoL of elderly people living in nursing homes, who often live with dementia. Although studies have suggested that self-perception of oral health can differ from objective oral conditions among the elderly, whether with or without dementia,<xref rid="b1-cia-12-659" ref-type="bibr">1</xref>,<xref rid="b19-cia-12-659" ref-type="bibr">19</xref> use of the GOHAI and OHIP among people with dementia is not yet well established in research. Ribeiro et al<xref rid="b19-cia-12-659" ref-type="bibr">19</xref> used the GOHAI to evaluate the OHRQoL of patients with dementia; to reduce the possibility of bias, participants in this study were assisted by their caregivers.</p><p>In a preliminary study of 94 nursing home residents living in four residential homes of the same care society, dementia was assessed using the Mini-Mental State Examination (MMSE),<xref rid="b20-cia-12-659" ref-type="bibr">20</xref> and possible factors affecting OHRQoL were assessed using the GOHAI.<xref rid="b18-cia-12-659" ref-type="bibr">18</xref> Initial results indicated that OHRQoL was associated with the type of denture worn but not with dementia.<xref rid="b18-cia-12-659" ref-type="bibr">18</xref> Larger sample sizes and a higher explanatory power would, however, be desirable to confirm these findings and to enable robust multivariate analysis to be conducted.</p><p>The objective of this study was, therefore, to evaluate the effect of prosthetic and dental statuses on OHRQoL among nursing home residents with or without dementia.</p></sec><sec sec-type="methods"><title>Methods</title><sec sec-type="methods"><title>Study setting</title><p>This study was approved by the local review board of the University of Heidelberg (approval number S-002/2012). Fourteen nursing homes in Baden-Württemberg, one of the 16 federal states of Germany, were selected by the Ministry of Social Affairs as representative of the state’s facilities to enable generalization of the results of the study. The nursing homes differed in size, location (urban and rural), and residents’ distribution. All residents, or, if they were not sui legis, their legal representatives, were asked to participate in the study. Written and oral information were provided by a dentist, and participants were asked to give consent. There were no other inclusion criteria, and 277 residents were included in the study. This study includes preliminary results for 94 participants living in the four homes of one care society; the results have been published elsewhere after the use of a different statistical approach.<xref rid="b20-cia-12-659" ref-type="bibr">20</xref></p></sec><sec><title>Sociodemographic variables and dementia</title><p>Age, gender, number of diseases, and permanent medication were extracted from the care documentation. These variables were assessed to estimate the general condition of the participants. Cognitive impairment of the participants was evaluated using the MMSE.<xref rid="b20-cia-12-659" ref-type="bibr">20</xref> Examinations were performed by four psychologists trained in the memory clinic of the University of Heidelberg. Using the MMSE requires participants to solve 30 tasks devised to enable the assessment of cognitive and motor skills. Correctly performed exercises were awarded one point, whereas failed exercises were awarded zero. Scores could therefore range from 0 to 30; scores <24 were regarded as indicative of dementia, as recommended in several studies.<xref rid="b20-cia-12-659" ref-type="bibr">20</xref>–<xref rid="b23-cia-12-659" ref-type="bibr">23</xref></p></sec><sec><title>Type of denture</title><p>Each participant underwent a comprehensive dental examination by two experienced dentists trained by investigation of elderly patients attending the Department of Prosthodontics, University of Heidelberg, before the start of the study. For the Revised Oral Assessment Guide (ROAG) used for estimation of dental treatment needs (see section ‘Dental treatment needs’) interexaminer reliability was studied (Cronbach’s alpha >0.9). Dental status, including number of natural teeth, type of denture, and denture-related treatment needs, was recorded for each participant. For analytical purposes, the type of denture was assigned to one of the following four categories: 1) edentulous without teeth replacement, 2) complete denture (CD), 3) removable dental prosthesis (RDP), and 4) natural teeth or fixed dental prosthesis (FDP). The type of denture worn was classified according to the weaker restored jaw.<xref rid="b16-cia-12-659" ref-type="bibr">16</xref> Denture-related problems were also assessed dichotomously (yes =1 and no =0).</p></sec><sec><title>Dental treatment needs</title><p>Dental treatment needs were evaluated using the ROAG. Saliva, swallow, speech, caries, mucosa, gums, denture retention, denture fitting, and denture condition were assessed dichotomously (0= healthy/1= treatment needed; maximum 12 points).<xref rid="b24-cia-12-659" ref-type="bibr">24</xref>,<xref rid="b25-cia-12-659" ref-type="bibr">25</xref></p></sec><sec><title>OHRQoL assessment</title><p>The German version of the GOHAI was used to assess OHRQoL. Using the GOHAI requires participants to answer 12 questions related to pain and/or discomfort and physical and/or psychosocial function with regard to oral condition on a 5-point scoring scale (5= always, 4= often, 3= sometimes, 2= seldom, and 1= never). Questions 3, 5, and 7 are inversely scaled (1= always and 5= never). The final GOHAI score can therefore range from 12 to 60 points. Patients with a low GOHAI have a worse OHRQoL.<xref rid="b12-cia-12-659" ref-type="bibr">12</xref>,<xref rid="b26-cia-12-659" ref-type="bibr">26</xref> In this study, the interviewers read the questions slowly. A copy of the questionnaire was also handed to the participants to enable them to read the questions themselves.</p><p>If the study dentist believed that the participant was unable to differentiate among the answer categories or gave invalid answers, the question was repeated. Such events were documented, and the results from these participants were excluded from statistical analysis (discussed in the “Results” section).</p></sec><sec><title>Statistical evaluation</title><p>Although the GOHAI scores were not normally distributed (Kolmogorov–Smirnov; <italic>P</italic><0.15), the residuals did not violate the assumption of normality (<italic>P</italic>>0.15). Parametric statistics were therefore used to describe and analyze the data. For descriptive purposes, mean, standard deviation, and frequencies were used. In bivariate analysis of association of the target variables with GOHAI score, categorized variables were compared using unpaired <italic>t</italic>-tests or generalized linear mixed equations whereas continuous variables were analyzed using Pearson correlations. The effect on OHRQoL of prosthetic restoration adjusted for the dichotomized variables age, number of teeth, ROAG (median), gender, and dementia. GOHAI <50 was taken as indicative of very compromised OHRQoL,<xref rid="b12-cia-12-659" ref-type="bibr">12</xref> which was analyzed using two multivariate models, one for all participants and one for residents wearing removable dentures only, with the additional factor conditions. Statistical analysis was performed using SPSS Version 23.0 (IBM Corporation, New York, NY, USA). The level of probability for local statistical significance was set to <italic>P</italic><0.05.</p></sec></sec><sec sec-type="results"><title>Results</title><p>Of the 277 participants initially included, 74 participants had to be excluded because they did not complete the GOHAI questionnaire (two participants were mute and 72 participants were unable to give valid answers to the questions). Thirty-four other participants had to be excluded from statistical analysis because of missing MMSE values. Thus, complete data for 169 participants were available for final analysis. The mean (SD) age of the study population was 82.9 (8.9) years. The majority of the participants were female (67%), and ~70% of the sample was living with dementia. The mean number of diseases was 3.5 (2.2), and the mean number of permanently taken medication was 6.7 (3.4). These variables reveal to a compromised general condition of the participants. The mean GOHAI score for the sample was 49.1 (8.3), and 70 participants (41%) had a GOHAI score of <50, which is indicative of compromised OHRQoL. The mean number of natural teeth was 8.3 (8.9); 32 participants wore an FDP, 37 participants wore removable partial dentures, and 90 participants wore CDs in at least one jaw. Ten participants were edentulous without teeth replacement in at least one jaw. The need for denture-related treatment among the sample was high (64%). Detailed data and results from bivariate comparisons of the participants’ characteristics are listed in <xref ref-type="table" rid="t1-cia-12-659">Table 1</xref>.</p><sec><title>Bivariate associations with OHRQoL</title><p>OHRQoL was significantly associated with the type of prosthetic restoration, with a linear decrease in OHRQoL from FDP, RPD, and CD to NP (<italic>P</italic><0.001). The number of natural teeth (<italic>P</italic><0.001) and the amount of dental treatment needed, as measured by mean values of the ROAG (<italic>P</italic>=0.049), also significantly affected OHRQoL. For denture wearers (n=137; 81%), a significant association of denture conditions (denture-associated treatment needs) with GOHAI was detected (<italic>P</italic>=0.013). None of the other comparisons of GOHAI scores between the target variables reached statistical significance (<italic>P</italic>>0.05). Detailed results from these analyses are listed in <xref ref-type="table" rid="t2-cia-12-659">Table 2</xref>.</p></sec><sec><title>Multivariate associations with OHRQoL</title><p>The logistic regression model for all participants (<italic>n</italic>=169) revealed a 6.5-fold risk (95% CI 1.3–32.4) of extremely compromised OHRQoL (GOHAI <50) among edentulous subjects without prosthetic restorations (<italic>P</italic><0.023). Furthermore, having fewer than five natural teeth independently doubled the risk of low OHRQoL (<italic>P</italic><0.036). None of the other confounders reached statistical significance (<italic>P</italic>>0.05, <xref ref-type="table" rid="t3-cia-12-659">Table 3</xref>). The regression model for denture wearers only (n=137) revealed a lower risk of reduced OHRQoL for participants older than the median (<italic>P</italic>=0.028). A ~2.5-fold risk of compromised OHRQoL was detected for participants with denture-related treatment needs (<italic>P</italic>=0.024). None of the other confounders, including the number of natural teeth, was found to affect OHRQoL (<xref ref-type="table" rid="t4-cia-12-659">Table 4</xref>).</p></sec></sec><sec sec-type="discussion"><title>Discussion</title><p>The results of this study suggest that better oral health (more natural teeth and adequate prosthetic restorations), especially, is positively associated with acceptable OHRQoL.</p><p>OHRQoL found in this study was usually substantially lower than that documented in previous studies investigating community-dwelling elderly;<xref rid="b25-cia-12-659" ref-type="bibr">25</xref>,<xref rid="b26-cia-12-659" ref-type="bibr">26</xref> this may be explained by the study of a specifically compromised nursing home sample facing a variety of dental treatment needs. Reduced OHRQoL might also be because the nursing home residents are provided with extensive prosthetic restorations, which can result in functional and esthetic compromises compared with natural dentition or fixed dental prostheses. In our recent study, 59% of the participants were edentulous in at least one jaw and 6% of the participants were edentulous without teeth replacement. In contrast, community-dwelling elderly have more teeth and a better prosthetic status than old people in nursing homes.<xref rid="b27-cia-12-659" ref-type="bibr">27</xref>,<xref rid="b28-cia-12-659" ref-type="bibr">28</xref></p><p>The relevance of prosthetic status to OHRQoL has, however, been proved for different communities, including young adults and community-dwelling elderly.<xref rid="b15-cia-12-659" ref-type="bibr">15</xref>,<xref rid="b29-cia-12-659" ref-type="bibr">29</xref> Accordingly, the most important reasons for better OHRQoL in this recent sample were dental in nature. With increasing number of natural teeth and the presence of FDP, higher OHRQoL was observed. These findings are also in accordance with those of Tramini et al,<xref rid="b14-cia-12-659" ref-type="bibr">14</xref> who also investigated a nursing home population (although the OHRQoL of participants in that study was not as compromised as in this recent study). In our study, participants with FDP had the highest OHRQoL, with a linear decrease from those with RDP and CDs to those who were edentulous and without dentures. This finding is not surprising and confirms our preliminary results for a smaller cohort of 94 participants published elsewhere.<xref rid="b20-cia-12-659" ref-type="bibr">20</xref> With loss of teeth, chewing ability also can be limited. Studies investigating masticatory performance revealed that chewing efficiency decreases from patients wearing FDP to those wearing RPD and CDP.<xref rid="b30-cia-12-659" ref-type="bibr">30</xref>–<xref rid="b32-cia-12-659" ref-type="bibr">32</xref> Reduced masticatory performance also affects food selection and can even result in a requirement for food with a mushy consistency. In this context, one should also consider that eating is an important social event and extremely meaningful as a constant daily routine for seniors in a nursing home.<xref rid="b16-cia-12-659" ref-type="bibr">16</xref> These results were confirmed by multivariate analysis; a 6.5-fold risk of extremely compromised OHRQoL (GOHAI <50) was, moreover, proved for edentulous people with no tooth replacement. However, the significant differences between wearing CD and RDP could not be reproduced in multivariate analysis, albeit there is a trend to a higher risk for those with CD (<italic>P</italic>=0.152). One might speculate that a possible difference between these groups can only be proved using a higher sample size.</p><p>Denture-related treatment needs also significantly affected OHRQoL. First, poorly fitting and less retentive dentures are associated with reduced chewing efficacy; second, bad denture condition results in psychological and social problems, which also affect OHRQoL. In this study, the need for denture-related treatment was higher (64%) but comparable to those detected in previous studies.<xref rid="b2-cia-12-659" ref-type="bibr">2</xref>,<xref rid="b19-cia-12-659" ref-type="bibr">19</xref> Although the number of general dental treatment needs, as measured using the ROAG, was associated with OHRQoL in bivariate analysis, this effect could not be confirmed by multivariate analysis. This finding is, nevertheless, in accordance with previous reports indicating discrepancies between objectively measured oral health (eg, gingivitis) and OHRQoL, especially among the elderly. OHRQoL is based on effects on daily performance, and some oral problems (eg, oral neglect) are asymptomatic or of minor significance in comparison with general health problems.</p><p>The finding that greater age is positively associated with better OHRQoL is in a similar direction. Interestingly, people with or without dementia had a comparable OHRQoL, even though objectively measured health indicators are frequently indicative of worse oral health (eg, periodontitis and caries) among subjects living with dementia, as reported in the literature.<xref rid="b19-cia-12-659" ref-type="bibr">19</xref>,<xref rid="b33-cia-12-659" ref-type="bibr">33</xref>,<xref rid="b34-cia-12-659" ref-type="bibr">34</xref> In our recent study, however, comparable dental and prosthetic statuses and prevalence of dental treatment needs were observed among those with or without dementia, leading to similar OHRQoL. Similar levels of OHRQoL among demented and “healthy” elderly people have also been detected in previous studies.<xref rid="b19-cia-12-659" ref-type="bibr">19</xref>,<xref rid="b35-cia-12-659" ref-type="bibr">35</xref></p><sec sec-type="methods"><title>Strength and weaknesses of the study</title><p>Dropout of ~40% in this study suggests caution in interpretation and generalization of the results. Participants were, perhaps, more interested in their health than nonre-sponders. It is also conceivable that some of the subjects participated in the study because they had acute dental problems. The sample is, however, a sub-population from a large, representative interdisciplinary study initiated by the Ministry of Social Affairs of the state of Baden-Württemberg, Germany. All potential residents of the participating nursing homes who gave written informed consent were included in the study (irrespective of cognitive status and care needs). It should be recognized that the comprehensive medical, psychological, and dental examinations were time-consuming (~2 h), which definitely led to concerns about participation in many cases. It should also be remembered that self-assessments of oral health by elderly subjects with dementia were performed in this study; this may not be consistently accurate and may lead to underestimation of oral problems. OHRQoL was, however, assessed using the GOHAI, which has been reported to enable more successful and sensitive detection of oral problems among compromised elderly populations than using the OHIP.<xref rid="b13-cia-12-659" ref-type="bibr">13</xref> In addition, the ability of the participants to give valid answers was confirmed by the interviewers in all cases. Each participant was asked the GOHAI questions and received the questionnaire to read, to reduce the possibility of bias. (As a consequence, results from 74 participants were excluded from statistical analysis.) We also stress that all dental examinations were performed by two dentists experienced in epidemiological surveys who received comprehensive training before the start of the study and tested their reliability in ROAG assessments.</p></sec></sec><sec><title>Conclusion</title><p>Among nursing home residents, OHRQoL and oral health conditions are severely compromised, and the need for denture-related treatment is high.</p><p>Dental and prosthetic conditions have a substantial effect on OHRQoL. Prevention of tooth loss at an early stage and denture-related treatments (adjustment of dentures) seem to be important to maintain high OHRQoL among the aged nursing home populations. Because measurement of OHRQoL might not fully capture objective oral health conditions for people with cognitive impairment or dementia, oral health should be periodically monitored. Frequent dentists’ visits to nursing homes would be desirable to prevent deterioration of oral conditions. Longitudinal studies are encouraged to confirm these results with a higher level of evidence.</p></sec></body><back><ack><title>Acknowledgments</title><p>We are grateful to all the participants in this study for their patience and to Altenpflegeheime Mannheim GmbH for their considerable support. We thank the Ministry of Social Affairs of Baden-Württemberg (Sozialministerium Baden-Württemberg) for financial support of the study. We also thank Ian Davis, copy editor, for English language revision.</p></ack><fn-group><fn><p><bold>Author contributions</bold></p><p>Anna-Luisa Klotz was responsible for data input and drafted the article. Alexander Jochen Hassel and Andreas Zenthöfer contributed to the study design and management. Johannes Schröder and Peter Rammelsberg critically revised the article. All authors contributed toward data analysis. All authors have read and approved the final article to be published. 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sample<break></break>(n=169)</th><th valign="top" align="left" rowspan="1" colspan="1"><italic>P</italic>-value</th></tr></thead><tbody><tr><td valign="top" align="left" rowspan="1" colspan="1">Age</td><td valign="top" align="left" rowspan="1" colspan="1">82.3 (8.9)</td><td valign="top" align="left" rowspan="1" colspan="1">83.1 (8.9)</td><td valign="top" align="left" rowspan="1" colspan="1">82.9 (8.9)</td><td valign="top" align="left" rowspan="1" colspan="1">0.594</td></tr><tr><td colspan="5" valign="top" align="left" rowspan="1">Gender<xref ref-type="table-fn" rid="tfn2-cia-12-659">a</xref></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> Male</td><td valign="top" align="left" rowspan="1" colspan="1">8 (18%)</td><td valign="top" align="left" rowspan="1" colspan="1">47 (38%)</td><td valign="top" align="left" rowspan="1" colspan="1">55 (33%)</td><td valign="top" align="left" rowspan="1" colspan="1"><bold>0.014</bold></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> Female</td><td valign="top" align="left" rowspan="1" colspan="1">37 (82%)</td><td valign="top" align="left" rowspan="1" colspan="1">77 (62%)</td><td valign="top" align="left" rowspan="1" colspan="1">114 (67%)</td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Disease</td><td valign="top" align="left" rowspan="1" colspan="1">3.3 (2.4)</td><td valign="top" align="left" rowspan="1" colspan="1">3.6 (2.2)</td><td valign="top" align="left" rowspan="1" colspan="1">3.5 (2.2)</td><td valign="top" align="left" rowspan="1" colspan="1">0.569</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Drugs</td><td valign="top" align="left" rowspan="1" colspan="1">7.2 (3.5)</td><td valign="top" align="left" rowspan="1" colspan="1">6.5 (3.3)</td><td valign="top" align="left" rowspan="1" colspan="1">6.7 (3.4)</td><td valign="top" align="left" rowspan="1" colspan="1">0.256</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Teeth</td><td valign="top" align="left" rowspan="1" colspan="1">8.1 (9.0)</td><td valign="top" align="left" rowspan="1" colspan="1">8.3 (8.9)</td><td valign="top" align="left" rowspan="1" colspan="1">8.3 (8.9)</td><td valign="top" align="left" rowspan="1" colspan="1">0.861</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">MMSE</td><td valign="top" align="left" rowspan="1" colspan="1">26.3 (1.8)</td><td valign="top" align="left" rowspan="1" colspan="1">12.5 (7.1)</td><td valign="top" align="left" rowspan="1" colspan="1">16.2 (8.6)</td><td valign="top" align="left" rowspan="1" colspan="1"><<bold>0.001</bold></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">GOHAI</td><td valign="top" align="left" rowspan="1" colspan="1">50.3 (8.4)</td><td valign="top" align="left" rowspan="1" colspan="1">48.6 (8.3)</td><td valign="top" align="left" rowspan="1" colspan="1">49.1 (8.3)</td><td valign="top" align="left" rowspan="1" colspan="1">0.234</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">ROAG</td><td valign="top" align="left" rowspan="1" colspan="1">2.1 (1.2)</td><td valign="top" align="left" rowspan="1" colspan="1">2.4 (1.4)</td><td valign="top" align="left" rowspan="1" colspan="1">2.3 (1.3)</td><td valign="top" align="left" rowspan="1" colspan="1">0.186</td></tr><tr><td colspan="5" valign="top" align="left" rowspan="1">Type of denture<xref ref-type="table-fn" rid="tfn2-cia-12-659">a</xref></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> FDP</td><td valign="top" align="left" rowspan="1" colspan="1">7 (16%)</td><td valign="top" align="left" rowspan="1" colspan="1">25 (20%)</td><td valign="top" align="left" rowspan="1" colspan="1">32 (19%)</td><td valign="top" align="left" rowspan="1" colspan="1">0.894</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> RDP</td><td valign="top" align="left" rowspan="1" colspan="1">11 (24%)</td><td valign="top" align="left" rowspan="1" colspan="1">26 (21%)</td><td valign="top" align="left" rowspan="1" colspan="1">37 (22%)</td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> CD</td><td valign="top" align="left" rowspan="1" colspan="1">24 (53%)</td><td valign="top" align="left" rowspan="1" colspan="1">66 (53%)</td><td valign="top" align="left" rowspan="1" colspan="1">90 (53%)</td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> E, NP</td><td valign="top" align="left" rowspan="1" colspan="1">3 (7%)</td><td valign="top" align="left" rowspan="1" colspan="1">7 (6%)</td><td valign="top" align="left" rowspan="1" colspan="1">10 (6%)</td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr><tr><td colspan="5" valign="top" align="left" rowspan="1">Denture condition (n=143)</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> Sufficient</td><td valign="top" align="left" rowspan="1" colspan="1">19 (42%)</td><td valign="top" align="left" rowspan="1" colspan="1">33 (34%)</td><td valign="top" align="left" rowspan="1" colspan="1">52 (36%)</td><td valign="top" align="left" rowspan="1" colspan="1">0.174</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> Insufficient</td><td valign="top" align="left" rowspan="1" colspan="1">26 (58%)</td><td valign="top" align="left" rowspan="1" colspan="1">65 (66%)</td><td valign="top" align="left" rowspan="1" colspan="1">91 (64%)</td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr></tbody></table><table-wrap-foot><fn id="tfn1-cia-12-659"><p><bold>Notes:</bold> D, suffering from dementia; ND, not suffering from dementia; E, NP, edentulous without teeth replacement. Significant <italic>P</italic>-values are marked in bold. Data are presented as mean (SD) or frequencies (<italic>n</italic>=169).</p></fn><fn id="tfn2-cia-12-659"><label>a</label><p>Chi-squared test.</p></fn><fn id="tfn3-cia-12-659"><p><bold>Abbreviations:</bold> CD, complete denture; FDP, fixed denture prosthesis; GOHAI, Geriatric Oral Health Assessment Index; MMSE, Mini-Mental State Examination; RDP, removable partial denture; ROAG, revised oral assessment guide; SD, standard deviation.</p></fn></table-wrap-foot></table-wrap><table-wrap id="t2-cia-12-659" position="float"><label>Table 2</label><caption><p>Target variables and their associations with OHRQoL (n=169)</p></caption><table frame="hsides" rules="groups"><thead><tr><th valign="top" align="left" rowspan="1" colspan="1">Variable</th><th valign="top" align="left" rowspan="1" colspan="1"><italic>R</italic></th><th valign="top" align="left" rowspan="1" colspan="1">GOHAI</th><th valign="top" align="left" rowspan="1" colspan="1"><italic>P</italic>-value</th></tr></thead><tbody><tr><td valign="top" align="left" rowspan="1" colspan="1">Age</td><td valign="top" align="left" rowspan="1" colspan="1">−0.079</td><td valign="top" align="left" rowspan="1" colspan="1">–</td><td valign="top" align="left" rowspan="1" colspan="1">0.305</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Gender</td><td valign="top" align="left" rowspan="1" colspan="1"></td><td valign="top" align="left" rowspan="1" colspan="1"></td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> Female</td><td valign="top" align="left" rowspan="1" colspan="1"><italic>–</italic></td><td valign="top" align="left" rowspan="1" colspan="1">48.5 (8.8)</td><td valign="top" align="left" rowspan="1" colspan="1">0.381</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> Male</td><td valign="top" align="left" rowspan="1" colspan="1"><italic>–</italic></td><td valign="top" align="left" rowspan="1" colspan="1">50.4 (7.0)</td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Diseases</td><td valign="top" align="left" rowspan="1" colspan="1">0.035</td><td valign="top" align="left" rowspan="1" colspan="1">–</td><td valign="top" align="left" rowspan="1" colspan="1">0.650</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Drugs</td><td valign="top" align="left" rowspan="1" colspan="1">−0.132</td><td valign="top" align="left" rowspan="1" colspan="1">–</td><td valign="top" align="left" rowspan="1" colspan="1">0.087</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Teeth</td><td valign="top" align="left" rowspan="1" colspan="1">0.286</td><td valign="top" align="left" rowspan="1" colspan="1">–</td><td valign="top" align="left" rowspan="1" colspan="1"><<bold>0.001</bold></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">ROAG</td><td valign="top" align="left" rowspan="1" colspan="1">−0.152</td><td valign="top" align="left" rowspan="1" colspan="1">–</td><td valign="top" align="left" rowspan="1" colspan="1"><bold>0.049</bold></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">No dementia</td><td valign="top" align="left" rowspan="1" colspan="1"></td><td valign="top" align="left" rowspan="1" colspan="1">50.3 (8.4)</td><td valign="top" align="left" rowspan="1" colspan="1">0.073</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Dementia</td><td valign="top" align="left" rowspan="1" colspan="1"></td><td valign="top" align="left" rowspan="1" colspan="1">48.6 (8.3)</td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Type of denture</td><td valign="top" align="left" rowspan="1" colspan="1"></td><td valign="top" align="left" rowspan="1" colspan="1"></td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> FDP</td><td valign="top" align="left" rowspan="1" colspan="1">–</td><td valign="top" align="left" rowspan="1" colspan="1">53.0 (6.6)</td><td valign="top" align="left" rowspan="1" colspan="1"><<bold>0.001</bold></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> RDP</td><td valign="top" align="left" rowspan="1" colspan="1">–</td><td valign="top" align="left" rowspan="1" colspan="1">49.6 (8.2)</td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> CDP</td><td valign="top" align="left" rowspan="1" colspan="1">–</td><td valign="top" align="left" rowspan="1" colspan="1">48.3 (8.2)</td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> E, NP</td><td valign="top" align="left" rowspan="1" colspan="1">–</td><td valign="top" align="left" rowspan="1" colspan="1">41.3 (8.4)</td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Denture condition (<italic>n</italic>=137)</td><td valign="top" align="left" rowspan="1" colspan="1"></td><td valign="top" align="left" rowspan="1" colspan="1"></td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> Sufficient</td><td valign="top" align="left" rowspan="1" colspan="1">–</td><td valign="top" align="left" rowspan="1" colspan="1">50.8 (6.7)</td><td valign="top" align="left" rowspan="1" colspan="1"><bold>0.013</bold></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1"> Insufficient</td><td valign="top" align="left" rowspan="1" colspan="1">–</td><td valign="top" align="left" rowspan="1" colspan="1">47.2 (8.8)</td><td valign="top" align="left" rowspan="1" colspan="1"></td></tr></tbody></table><table-wrap-foot><fn id="tfn4-cia-12-659"><p><bold>Notes:</bold> E, NP, edentulous without teeth replacement. Pearson’s correlation for continuous variables; <italic>t</italic>-tests or generalized linear mixed equations for categorized variables. Significant <italic>P</italic>-values are marked in bold.</p></fn><fn id="tfn5-cia-12-659"><p><bold>Abbreviations:</bold> CDP, complete denture prosthesis; FDP, fixed denture prosthesis; GOHAI, Geriatric Oral Health Assessment Index; OHRQoL, oral health-related quality of life; ROAG, revised oral assessment guide; RPD, removable partial denture.</p></fn></table-wrap-foot></table-wrap><table-wrap id="t3-cia-12-659" position="float"><label>Table 3</label><caption><p>Multivariate logistic regression model with a GOHAI cutoff value of 50 as the dependent variable and with the independent dichotomized confounders for all participants (n=169)</p></caption><table frame="hsides" rules="groups"><thead><tr><th valign="top" align="left" rowspan="1" colspan="1">Confounder</th><th valign="top" align="left" rowspan="1" colspan="1">Odds ratio</th><th valign="top" align="left" rowspan="1" colspan="1">Lower border, 95% CI</th><th valign="top" align="left" rowspan="1" colspan="1">Upper limit, 95% CI</th><th valign="top" align="left" rowspan="1" colspan="1"><italic>P</italic>-value</th></tr></thead><tbody><tr><td valign="top" align="left" rowspan="1" colspan="1">Age (older)</td><td valign="top" align="left" rowspan="1" colspan="1">0.5</td><td valign="top" align="left" rowspan="1" colspan="1">0.3</td><td valign="top" align="left" rowspan="1" colspan="1">1.0</td><td valign="top" align="left" rowspan="1" colspan="1">0.066</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Gender (male)</td><td valign="top" align="left" rowspan="1" colspan="1">0.6</td><td valign="top" align="left" rowspan="1" colspan="1">0.3</td><td valign="top" align="left" rowspan="1" colspan="1">1.2</td><td valign="top" align="left" rowspan="1" colspan="1">0.128</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Dementia</td><td valign="top" align="left" rowspan="1" colspan="1">1.6</td><td valign="top" align="left" rowspan="1" colspan="1">0.8</td><td valign="top" align="left" rowspan="1" colspan="1">3.5</td><td valign="top" align="left" rowspan="1" colspan="1">0.211</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">ROAG (more problems)</td><td valign="top" align="left" rowspan="1" colspan="1">1.0</td><td valign="top" align="left" rowspan="1" colspan="1">0.5</td><td valign="top" align="left" rowspan="1" colspan="1">2.3</td><td valign="top" align="left" rowspan="1" colspan="1">0.866</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Type of denture<xref ref-type="table-fn" rid="tfn7-cia-12-659">a</xref></td><td valign="top" align="left" rowspan="1" colspan="1">6.5</td><td valign="top" align="left" rowspan="1" colspan="1">1.3</td><td valign="top" align="left" rowspan="1" colspan="1">32.4</td><td valign="top" align="left" rowspan="1" colspan="1"><bold>0.023</bold></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Number of teeth (<5)</td><td valign="top" align="left" rowspan="1" colspan="1">2.0</td><td valign="top" align="left" rowspan="1" colspan="1">1.0</td><td valign="top" align="left" rowspan="1" colspan="1">4.0</td><td valign="top" align="left" rowspan="1" colspan="1"><bold>0.036</bold></td></tr></tbody></table><table-wrap-foot><fn id="tfn6-cia-12-659"><p><bold>Notes:</bold> Significant <italic>P</italic>-values are marked in bold.</p></fn><fn id="tfn7-cia-12-659"><label>a</label><p>Analysis of no prosthetic restoration in case of edentulism vs CD, RDP, and FDP.</p></fn><fn id="tfn8-cia-12-659"><p><bold>Abbreviations:</bold> CD, complete denture; FDP, fixed denture prosthesis; GOHAI, Geriatric Oral Health Assessment Index; ROAG, revised oral assessment guide; RPD, removable partial denture.</p></fn></table-wrap-foot></table-wrap><table-wrap id="t4-cia-12-659" position="float"><label>Table 4</label><caption><p>Multivariate logistic regression model with a GOHAI cutoff value of 50 as the dependent variable and with the independent dichotomized confounders for denture wearers only (n=137)</p></caption><table frame="hsides" rules="groups"><thead><tr><th valign="top" align="left" rowspan="1" colspan="1">Confounder</th><th valign="top" align="left" rowspan="1" colspan="1">Odds ratio</th><th valign="top" align="left" rowspan="1" colspan="1">Lower border, 95% CI</th><th valign="top" align="left" rowspan="1" colspan="1">Upper limit, 95% CI</th><th valign="top" align="left" rowspan="1" colspan="1"><italic>P</italic>-value</th></tr></thead><tbody><tr><td valign="top" align="left" rowspan="1" colspan="1">Age (older)</td><td valign="top" align="left" rowspan="1" colspan="1">0.4</td><td valign="top" align="left" rowspan="1" colspan="1">0.2</td><td valign="top" align="left" rowspan="1" colspan="1">0.9</td><td valign="top" align="left" rowspan="1" colspan="1"><bold>0.028</bold></td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Gender (male)</td><td valign="top" align="left" rowspan="1" colspan="1">0.7</td><td valign="top" align="left" rowspan="1" colspan="1">0.3</td><td valign="top" align="left" rowspan="1" colspan="1">1.6</td><td valign="top" align="left" rowspan="1" colspan="1">0.340</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Dementia</td><td valign="top" align="left" rowspan="1" colspan="1">1.7</td><td valign="top" align="left" rowspan="1" colspan="1">0.8</td><td valign="top" align="left" rowspan="1" colspan="1">3.4</td><td valign="top" align="left" rowspan="1" colspan="1">0.178</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">ROAG (more problems)</td><td valign="top" align="left" rowspan="1" colspan="1">0.7</td><td valign="top" align="left" rowspan="1" colspan="1">0.3</td><td valign="top" align="left" rowspan="1" colspan="1">1.7</td><td valign="top" align="left" rowspan="1" colspan="1">0.492</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Type of denture<xref ref-type="table-fn" rid="tfn10-cia-12-659">a</xref></td><td valign="top" align="left" rowspan="1" colspan="1">2.1</td><td valign="top" align="left" rowspan="1" colspan="1">0.8</td><td valign="top" align="left" rowspan="1" colspan="1">5.6</td><td valign="top" align="left" rowspan="1" colspan="1">0.152</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Number of teeth (<5)</td><td valign="top" align="left" rowspan="1" colspan="1">1.1</td><td valign="top" align="left" rowspan="1" colspan="1">0.4</td><td valign="top" align="left" rowspan="1" colspan="1">2.6</td><td valign="top" align="left" rowspan="1" colspan="1">0.915</td></tr><tr><td valign="top" align="left" rowspan="1" colspan="1">Denture condition insufficient</td><td valign="top" align="left" rowspan="1" colspan="1">2.4</td><td valign="top" align="left" rowspan="1" colspan="1">1.1</td><td valign="top" align="left" rowspan="1" colspan="1">5.0</td><td valign="top" align="left" rowspan="1" colspan="1"><bold>0.024</bold></td></tr></tbody></table><table-wrap-foot><fn id="tfn9-cia-12-659"><p><bold>Notes:</bold> Significant <italic>P</italic>-values are marked in bold.</p></fn><fn id="tfn10-cia-12-659"><label>a</label><p>Analysis: CD vs RPD.</p></fn><fn id="tfn11-cia-12-659"><p><bold>Abbreviations:</bold> CD, complete denture; 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