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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Predicted vitamin D status and incidence of tooth loss and periodontitis</title><author><name sortKey="Jimenez, Monik" sort="Jimenez, Monik" uniqKey="Jimenez M" first="Monik" last="Jimenez">Monik Jimenez</name><affiliation><nlm:aff id="A1">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Giovannucci, Edward" sort="Giovannucci, Edward" uniqKey="Giovannucci E" first="Edward" last="Giovannucci">Edward Giovannucci</name><affiliation><nlm:aff id="A2">Department of Nutrition, Harvard School of Public Health, Boston, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Kaye, Elizabeth Krall" sort="Kaye, Elizabeth Krall" uniqKey="Kaye E" first="Elizabeth Krall" last="Kaye">Elizabeth Krall Kaye</name><affiliation><nlm:aff id="A3">Department of Health Policy and Health Services Research, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Joshipura, Kaumudi J" sort="Joshipura, Kaumudi J" uniqKey="Joshipura K" first="Kaumudi J" last="Joshipura">Kaumudi J. Joshipura</name><affiliation><nlm:aff id="A4">University of Puerto Rico School of Dentistry, San Juan, Puerto Rico</nlm:aff></affiliation></author><author><name sortKey="Dietrich, Thomas" sort="Dietrich, Thomas" uniqKey="Dietrich T" first="Thomas" last="Dietrich">Thomas Dietrich</name><affiliation><nlm:aff id="A5">Department of Oral Surgery, The School of Dentistry, University of Birmingham, St Chad’s Queensway, Birmingham B4 6NN, UK</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23469936</idno><idno type="pmc">4911807</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911807</idno><idno type="RBID">PMC:4911807</idno><idno type="doi">10.1017/S1368980013000177</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">002797</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002797</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Predicted vitamin D status and incidence of tooth loss and periodontitis</title><author><name sortKey="Jimenez, Monik" sort="Jimenez, Monik" uniqKey="Jimenez M" first="Monik" last="Jimenez">Monik Jimenez</name><affiliation><nlm:aff id="A1">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Giovannucci, Edward" sort="Giovannucci, Edward" uniqKey="Giovannucci E" first="Edward" last="Giovannucci">Edward Giovannucci</name><affiliation><nlm:aff id="A2">Department of Nutrition, Harvard School of Public Health, Boston, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Kaye, Elizabeth Krall" sort="Kaye, Elizabeth Krall" uniqKey="Kaye E" first="Elizabeth Krall" last="Kaye">Elizabeth Krall Kaye</name><affiliation><nlm:aff id="A3">Department of Health Policy and Health Services Research, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA</nlm:aff></affiliation></author><author><name sortKey="Joshipura, Kaumudi J" sort="Joshipura, Kaumudi J" uniqKey="Joshipura K" first="Kaumudi J" last="Joshipura">Kaumudi J. Joshipura</name><affiliation><nlm:aff id="A4">University of Puerto Rico School of Dentistry, San Juan, Puerto Rico</nlm:aff></affiliation></author><author><name sortKey="Dietrich, Thomas" sort="Dietrich, Thomas" uniqKey="Dietrich T" first="Thomas" last="Dietrich">Thomas Dietrich</name><affiliation><nlm:aff id="A5">Department of Oral Surgery, The School of Dentistry, University of Birmingham, St Chad’s Queensway, Birmingham B4 6NN, UK</nlm:aff></affiliation></author></analytic><series><title level="j">Public health nutrition</title><idno type="ISSN">1368-9800</idno><idno type="eISSN">1475-2727</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objective</title><p id="P1">Vitamin D insufficiency is highly prevalent, with particular subgroups at greater risk (e.g. the elderly and those with darker skin). Vitamin D insufficiency may partly explain US racial/ethnic disparities in the prevalence of periodontitis and tooth loss. We evaluated the association between a predictor score of plasma 25-hydroxyvitamin D (25(OH)D) and incidence of periodontitis and tooth loss.</p></sec><sec id="S2"><title>Design</title><p id="P2">Detailed biennial questionnaires were collected on medical history, lifestyle practices and incident periodontitis and tooth loss. The predictor score was derived from variables known to influence circulating concentrations of plasma 25(OH)D and validated against plasma concentrations among a sub-sample. Multivariable Cox proportional-hazards models with time-varying covariates estimated the association between the predicted 25(OH)D score and time until first tooth loss.</p></sec><sec id="S3"><title>Subjects</title><p id="P3">A total of 42 730 participants of the Health Professionals Follow-Up Study aged 40–75 years at baseline were followed from 1986 to 2006.</p></sec><sec id="S4"><title>Setting</title><p id="P4">USA, representing all fifty states and the District of Columbia.</p></sec><sec id="S5"><title>Results</title><p id="P5">We observed 13 581 incident tooth loss events from 539 335 person-years. There was a dose-dependent significant inverse association across quintiles of the predicted 25(OH)D score and incidence of tooth loss. In multivariable analyses, the highest quintile of the updated predicted 25(OH)D score compared with the lowest was associated with a 20 % lower incidence of tooth loss (hazard ratio 5 0·80, 95 % CI 0·76, 0·85; <italic>P</italic> value for trend <0·0 0 1); UV-B was also independently associated. Results for the predicted 25(OH)D score and periodontitis were similar.</p></sec><sec id="S6"><title>Conclusions</title><p id="P6">These results are suggestive of an association between predictors of vitamin D and lower incidence of tooth loss and periodontitis.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9808463</journal-id><journal-id journal-id-type="pubmed-jr-id">21444</journal-id><journal-id journal-id-type="nlm-ta">Public Health Nutr</journal-id><journal-id journal-id-type="iso-abbrev">Public Health Nutr</journal-id><journal-title-group><journal-title>Public health nutrition</journal-title></journal-title-group><issn pub-type="ppub">1368-9800</issn><issn pub-type="epub">1475-2727</issn></journal-meta><article-meta><article-id pub-id-type="pmid">23469936</article-id><article-id pub-id-type="pmc">4911807</article-id><article-id pub-id-type="doi">10.1017/S1368980013000177</article-id><article-id pub-id-type="manuscript">NIHMS793733</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Predicted vitamin D status and incidence of tooth loss and periodontitis</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Jimenez</surname><given-names>Monik</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Giovannucci</surname><given-names>Edward</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Kaye</surname><given-names>Elizabeth Krall</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Joshipura</surname><given-names>Kaumudi J</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Dietrich</surname><given-names>Thomas</given-names></name><xref ref-type="aff" rid="A5">5</xref><xref ref-type="corresp" rid="CR1">*</xref></contrib></contrib-group><aff id="A1"><label>1</label>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, MA, USA</aff><aff id="A2"><label>2</label>Department of Nutrition, Harvard School of Public Health, Boston, MA, USA</aff><aff id="A3"><label>3</label>Department of Health Policy and Health Services Research, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA</aff><aff id="A4"><label>4</label>University of Puerto Rico School of Dentistry, San Juan, Puerto Rico</aff><aff id="A5"><label>5</label>Department of Oral Surgery, The School of Dentistry, University of Birmingham, St Chad’s Queensway, Birmingham B4 6NN, UK</aff><author-notes><corresp id="CR1"><label>*</label><italic>Corresponding author:</italic><email>t.dietrich@bham.ac.uk</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>10</day><month>6</month><year>2016</year></pub-date><pub-date pub-type="epub"><day>07</day><month>3</month><year>2013</year></pub-date><pub-date pub-type="ppub"><month>4</month><year>2014</year></pub-date><pub-date pub-type="pmc-release"><day>17</day><month>6</month><year>2016</year></pub-date><volume>17</volume><issue>4</issue><fpage>844</fpage><lpage>852</lpage><pmc-comment>elocation-id from pubmed: 10.1017/S1368980013000177</pmc-comment>
<abstract><sec id="S1"><title>Objective</title><p id="P1">Vitamin D insufficiency is highly prevalent, with particular subgroups at greater risk (e.g. the elderly and those with darker skin). Vitamin D insufficiency may partly explain US racial/ethnic disparities in the prevalence of periodontitis and tooth loss. We evaluated the association between a predictor score of plasma 25-hydroxyvitamin D (25(OH)D) and incidence of periodontitis and tooth loss.</p></sec><sec id="S2"><title>Design</title><p id="P2">Detailed biennial questionnaires were collected on medical history, lifestyle practices and incident periodontitis and tooth loss. The predictor score was derived from variables known to influence circulating concentrations of plasma 25(OH)D and validated against plasma concentrations among a sub-sample. Multivariable Cox proportional-hazards models with time-varying covariates estimated the association between the predicted 25(OH)D score and time until first tooth loss.</p></sec><sec id="S3"><title>Subjects</title><p id="P3">A total of 42 730 participants of the Health Professionals Follow-Up Study aged 40–75 years at baseline were followed from 1986 to 2006.</p></sec><sec id="S4"><title>Setting</title><p id="P4">USA, representing all fifty states and the District of Columbia.</p></sec><sec id="S5"><title>Results</title><p id="P5">We observed 13 581 incident tooth loss events from 539 335 person-years. There was a dose-dependent significant inverse association across quintiles of the predicted 25(OH)D score and incidence of tooth loss. In multivariable analyses, the highest quintile of the updated predicted 25(OH)D score compared with the lowest was associated with a 20 % lower incidence of tooth loss (hazard ratio 5 0·80, 95 % CI 0·76, 0·85; <italic>P</italic> value for trend <0·0 0 1); UV-B was also independently associated. Results for the predicted 25(OH)D score and periodontitis were similar.</p></sec><sec id="S6"><title>Conclusions</title><p id="P6">These results are suggestive of an association between predictors of vitamin D and lower incidence of tooth loss and periodontitis.</p></sec></abstract><kwd-group><kwd>Vitamin D</kwd><kwd>25-Hydroxyvitamin D</kwd><kwd>Tooth loss</kwd><kwd>Periodontitis</kwd><kwd>Oral health</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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