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<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Number of Teeth and Mortality Risk in the Baltimore Longitudinal Study of Aging</title>
<author>
<name sortKey="Padilha, Dalva Maria Pereira" sort="Padilha, Dalva Maria Pereira" uniqKey="Padilha D" first="Dalva Maria Pereira" last="Padilha">Dalva Maria Pereira Padilha</name>
<affiliation>
<nlm:aff id="A1">Community Oral Health Department, Dental School, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Hilgert, Juliana Balbinot" sort="Hilgert, Juliana Balbinot" uniqKey="Hilgert J" first="Juliana Balbinot" last="Hilgert">Juliana Balbinot Hilgert</name>
<affiliation>
<nlm:aff id="A2">Post-Graduate Program in Community Health and Post-Graduate Program in Dentistry, Lutheran University of Brazil–Canoas, RS, Brazil</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Hugo, Fernando Neves" sort="Hugo, Fernando Neves" uniqKey="Hugo F" first="Fernando Neves" last="Hugo">Fernando Neves Hugo</name>
<affiliation>
<nlm:aff id="A1">Community Oral Health Department, Dental School, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="B S, Angelo Jose Goncalves" sort="B S, Angelo Jose Goncalves" uniqKey="B S A" first="Ângelo José Gonçalves" last="B S">Ângelo José Gonçalves B S</name>
<affiliation>
<nlm:aff id="A3">Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name>
<affiliation>
<nlm:aff id="A3">Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</nlm:aff>
</affiliation>
</author>
</titleStmt>
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<idno type="wicri:source">PMC</idno>
<idno type="pmid">18693229</idno>
<idno type="pmc">4984838</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984838</idno>
<idno type="RBID">PMC:4984838</idno>
<date when="2008">2008</date>
<idno type="wicri:Area/Pmc/Corpus">002783</idno>
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<title xml:lang="en" level="a" type="main">Number of Teeth and Mortality Risk in the Baltimore Longitudinal Study of Aging</title>
<author>
<name sortKey="Padilha, Dalva Maria Pereira" sort="Padilha, Dalva Maria Pereira" uniqKey="Padilha D" first="Dalva Maria Pereira" last="Padilha">Dalva Maria Pereira Padilha</name>
<affiliation>
<nlm:aff id="A1">Community Oral Health Department, Dental School, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Hilgert, Juliana Balbinot" sort="Hilgert, Juliana Balbinot" uniqKey="Hilgert J" first="Juliana Balbinot" last="Hilgert">Juliana Balbinot Hilgert</name>
<affiliation>
<nlm:aff id="A2">Post-Graduate Program in Community Health and Post-Graduate Program in Dentistry, Lutheran University of Brazil–Canoas, RS, Brazil</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Hugo, Fernando Neves" sort="Hugo, Fernando Neves" uniqKey="Hugo F" first="Fernando Neves" last="Hugo">Fernando Neves Hugo</name>
<affiliation>
<nlm:aff id="A1">Community Oral Health Department, Dental School, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="B S, Angelo Jose Goncalves" sort="B S, Angelo Jose Goncalves" uniqKey="B S A" first="Ângelo José Gonçalves" last="B S">Ângelo José Gonçalves B S</name>
<affiliation>
<nlm:aff id="A3">Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name>
<affiliation>
<nlm:aff id="A3">Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">The journals of gerontology. Series A, Biological sciences and medical sciences</title>
<idno type="ISSN">1079-5006</idno>
<idno type="eISSN">1758-535X</idno>
<imprint>
<date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
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<textClass></textClass>
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</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<sec id="S1">
<title>Background</title>
<p id="P1">Findings from several studies suggested an association between oral health and several health outcomes including cardiovascular disease, aspiration pneumonia, malnutrition, poor quality of life, and mortality. Using data from the Baltimore Longitudinal Study of Aging (BLSA), we tested the hypothesis that number of teeth is indicative of mortality risk independent of other confounders.</p>
</sec>
<sec id="S2">
<title>Methods</title>
<p id="P2">Dentists conducted a standardized oral examination that included tooth count, tooth with coronal and cervical caries count, and gingival and periodontal index. Blood tests used in the analysis included fasting glucose, oral glucose tolerance test, serum low-density lipoprotein (LDL), high-density lipoprotein (HDL) cholesterol, triglycerides, and white blood cell counts. Physical activity, skin fold thickness, body mass index and chronic diseases were also evaluated.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P3">Of the 500 BLSA participants evaluated, 198 died an average of 130 (±75) months postdental evaluation, and 302 survivors were followed for a mean of 185 (±90) months. Based on multivariate Cox regression models, being edentulous or having than 20 teeth was independently associated with mortality.</p>
</sec>
<sec id="S4">
<title>Conclusion</title>
<p id="P4">The results of this study support the notion that number of teeth is a significant and independent risk indicator for early mortality. These findings suggest that the improvement of oral health may have a positive impact on general health and may delay mortality.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-journal-id">9502837</journal-id>
<journal-id journal-id-type="pubmed-jr-id">8622</journal-id>
<journal-id journal-id-type="nlm-ta">J Gerontol A Biol Sci Med Sci</journal-id>
<journal-id journal-id-type="iso-abbrev">J. Gerontol. A Biol. Sci. Med. Sci.</journal-id>
<journal-title-group>
<journal-title>The journals of gerontology. Series A, Biological sciences and medical sciences</journal-title>
</journal-title-group>
<issn pub-type="ppub">1079-5006</issn>
<issn pub-type="epub">1758-535X</issn>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">18693229</article-id>
<article-id pub-id-type="pmc">4984838</article-id>
<article-id pub-id-type="manuscript">NIHMS809135</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Number of Teeth and Mortality Risk in the Baltimore Longitudinal Study of Aging</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Padilha</surname>
<given-names>Dalva Maria Pereira</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Hilgert</surname>
<given-names>Juliana Balbinot</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Hugo</surname>
<given-names>Fernando Neves</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bós</surname>
<given-names>Ângelo José Gonçalves</given-names>
</name>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Ferrucci</surname>
<given-names>Luigi</given-names>
</name>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
</contrib-group>
<aff id="A1">
<label>1</label>
Community Oral Health Department, Dental School, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil</aff>
<aff id="A2">
<label>2</label>
Post-Graduate Program in Community Health and Post-Graduate Program in Dentistry, Lutheran University of Brazil–Canoas, RS, Brazil</aff>
<aff id="A3">
<label>3</label>
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</aff>
<author-notes>
<corresp id="FN1">Address correspondence to Dalva Maria Pereira Padilha, PhD, Dental School, UFRGS, R. Ramiro Barcelos, 2492. Porto Alegre, RS 90035-003, Brazil.
<email>dalvapadilha@via-rs.net</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted">
<day>10</day>
<month>8</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="ppub">
<month>7</month>
<year>2008</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>15</day>
<month>8</month>
<year>2016</year>
</pub-date>
<volume>63</volume>
<issue>7</issue>
<fpage>739</fpage>
<lpage>744</lpage>
<abstract>
<sec id="S1">
<title>Background</title>
<p id="P1">Findings from several studies suggested an association between oral health and several health outcomes including cardiovascular disease, aspiration pneumonia, malnutrition, poor quality of life, and mortality. Using data from the Baltimore Longitudinal Study of Aging (BLSA), we tested the hypothesis that number of teeth is indicative of mortality risk independent of other confounders.</p>
</sec>
<sec id="S2">
<title>Methods</title>
<p id="P2">Dentists conducted a standardized oral examination that included tooth count, tooth with coronal and cervical caries count, and gingival and periodontal index. Blood tests used in the analysis included fasting glucose, oral glucose tolerance test, serum low-density lipoprotein (LDL), high-density lipoprotein (HDL) cholesterol, triglycerides, and white blood cell counts. Physical activity, skin fold thickness, body mass index and chronic diseases were also evaluated.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P3">Of the 500 BLSA participants evaluated, 198 died an average of 130 (±75) months postdental evaluation, and 302 survivors were followed for a mean of 185 (±90) months. Based on multivariate Cox regression models, being edentulous or having than 20 teeth was independently associated with mortality.</p>
</sec>
<sec id="S4">
<title>Conclusion</title>
<p id="P4">The results of this study support the notion that number of teeth is a significant and independent risk indicator for early mortality. These findings suggest that the improvement of oral health may have a positive impact on general health and may delay mortality.</p>
</sec>
</abstract>
<kwd-group>
<kwd>Aged</kwd>
<kwd>Mortality</kwd>
<kwd>Cohort studies</kwd>
<kwd>Tooth loss</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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