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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Prevalence and Clinical Significance of Supine-Dependent Obstructive Sleep Apnea in Patients Using Oral Appliance Therapy</title><author><name sortKey="Dieltjens, Marijke" sort="Dieltjens, Marijke" uniqKey="Dieltjens M" first="Marijke" last="Dieltjens">Marijke Dieltjens</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation><affiliation><nlm:aff id="aff2">Otolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="aff4">Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium</nlm:aff></affiliation></author><author><name sortKey="Braem, Marc J" sort="Braem, Marc J" uniqKey="Braem M" first="Marc J." last="Braem">Marc J. Braem</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation><affiliation><nlm:aff id="aff4">Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium</nlm:aff></affiliation></author><author><name sortKey="Van De Heyning, Paul H" sort="Van De Heyning, Paul H" uniqKey="Van De Heyning P" first="Paul H." last="Van De Heyning">Paul H. Van De Heyning</name><affiliation><nlm:aff id="aff2">Otolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="aff4">Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium</nlm:aff></affiliation></author><author><name sortKey="Wouters, Kristien" sort="Wouters, Kristien" uniqKey="Wouters K" first="Kristien" last="Wouters">Kristien Wouters</name><affiliation><nlm:aff id="aff3">Scientific Coordination and Biostatistics, Antwerp University Hospital, Edegem, Antwerp, Belgium</nlm:aff></affiliation></author><author><name sortKey="Vanderveken, Olivier M" sort="Vanderveken, Olivier M" uniqKey="Vanderveken O" first="Olivier M." last="Vanderveken">Olivier M. Vanderveken</name><affiliation><nlm:aff id="aff2">Otolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="aff4">Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25142766</idno><idno type="pmc">4153117</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153117</idno><idno type="RBID">PMC:4153117</idno><idno type="doi">10.5664/jcsm.4024</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">002413</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002413</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Prevalence and Clinical Significance of Supine-Dependent Obstructive Sleep Apnea in Patients Using Oral Appliance Therapy</title><author><name sortKey="Dieltjens, Marijke" sort="Dieltjens, Marijke" uniqKey="Dieltjens M" first="Marijke" last="Dieltjens">Marijke Dieltjens</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation><affiliation><nlm:aff id="aff2">Otolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="aff4">Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium</nlm:aff></affiliation></author><author><name sortKey="Braem, Marc J" sort="Braem, Marc J" uniqKey="Braem M" first="Marc J." last="Braem">Marc J. Braem</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation><affiliation><nlm:aff id="aff4">Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium</nlm:aff></affiliation></author><author><name sortKey="Van De Heyning, Paul H" sort="Van De Heyning, Paul H" uniqKey="Van De Heyning P" first="Paul H." last="Van De Heyning">Paul H. Van De Heyning</name><affiliation><nlm:aff id="aff2">Otolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="aff4">Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium</nlm:aff></affiliation></author><author><name sortKey="Wouters, Kristien" sort="Wouters, Kristien" uniqKey="Wouters K" first="Kristien" last="Wouters">Kristien Wouters</name><affiliation><nlm:aff id="aff3">Scientific Coordination and Biostatistics, Antwerp University Hospital, Edegem, Antwerp, Belgium</nlm:aff></affiliation></author><author><name sortKey="Vanderveken, Olivier M" sort="Vanderveken, Olivier M" uniqKey="Vanderveken O" first="Olivier M." last="Vanderveken">Olivier M. Vanderveken</name><affiliation><nlm:aff id="aff2">Otolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium</nlm:aff></affiliation><affiliation><nlm:aff id="aff4">Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium</nlm:aff></affiliation></author></analytic><series><title level="j">Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine</title><idno type="ISSN">1550-9389</idno><idno type="eISSN">1550-9397</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Study Objective:</title><p>The prevalence of supine-dependent obstructive sleep apnea (sdOSA) in a general population ranges from 20% to 60%, depending on the criteria used. Currently, the prevalence and evolution of sdOSA once oral appliance therapy with a mandibular advancement device (OA<sub>m</sub>) has started is unknown. In addition, literature on the correlation between sdOSA and treatment success with OA<sub>m</sub> is not unequivocal. The first purpose of this study was to assess the prevalence of sdOSA before and under OA<sub>m</sub> therapy. Second, the conversion rate from non-sdOSA to sdOSA during OA<sub>m</sub> therapy was evaluated. The third and final goal was to analyze the correlation between sdOSA and treatment success with OA<sub>m</sub> therapy in the patient population.</p></sec><sec><title>Methods:</title><p>Two hundred thirty-seven consecutive patients (age 48 ± 9 years; male/female ratio 173/64; AHI 20.1 ± 14.7 events/h; BMI 27.2 ± 4.3 kg/m<sup>2</sup>) starting OA<sub>m</sub> therapy were included.</p></sec><sec><title>Results:</title><p>The prevalence of sdOSA before the start of OA<sub>m</sub> therapy, ranged from 27.0% to 67.5%. The prevalence of residual sdOSA under OA<sub>m</sub> therapy in this study ranged from 17.5% to 33.9%. Second, the conversion rate from non-sdOSA to sdOSA ranged from 23.0% to 37.5%. Third, the presence of sdOSA at baseline was not a significant factor for treatment success with OA<sub>m</sub> therapy.</p></sec><sec><title>Conclusions:</title><p>The results of this study indicate that the prevalence of sdOSA before and under OA<sub>m</sub> therapy is relatively high. One-third of patients shift from non-sdOSA to sdOSA. Finally, treatment success for OA<sub>m</sub> therapy was not significantly correlated with the presence of sdOSA at baseline.</p></sec><sec><title>Citation:</title><p>Dieltjens M, Braem MJ, Van de Heyning PH, Wouters K, Vanderveken OM. Prevalence and clinical significance of supine-dependent obstructive sleep apnea in patients using oral appliance therapy. <italic>J Clin Sleep Med</italic> 2014;10(9):959-964.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Clin Sleep Med</journal-id><journal-id journal-id-type="iso-abbrev">J Clin Sleep Med</journal-id><journal-id journal-id-type="publisher-id">JCSM</journal-id><journal-title-group><journal-title>Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine</journal-title></journal-title-group><issn pub-type="ppub">1550-9389</issn><issn pub-type="epub">1550-9397</issn><publisher><publisher-name>American Academy of Sleep Medicine</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25142766</article-id><article-id pub-id-type="pmc">4153117</article-id><article-id pub-id-type="publisher-id">jc-00321-13</article-id><article-id pub-id-type="doi">10.5664/jcsm.4024</article-id><article-categories><subj-group subj-group-type="heading"><subject>New Research</subject><subj-group><subject>Scientific Investigations</subject></subj-group></subj-group></article-categories><title-group><article-title>Prevalence and Clinical Significance of Supine-Dependent Obstructive Sleep Apnea in Patients Using Oral Appliance Therapy</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Dieltjens</surname><given-names>Marijke</given-names></name><degrees>M.B.S.</degrees><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="aff" rid="aff4"><sup>4</sup></xref><xref ref-type="corresp" rid="cor1"></xref></contrib><contrib contrib-type="author"><name><surname>Braem</surname><given-names>Marc J.</given-names></name><degrees>D.D.S., Ph.D.</degrees><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Van de Heyning</surname><given-names>Paul H.</given-names></name><degrees>M.D., Ph.D.</degrees><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Wouters</surname><given-names>Kristien</given-names></name><degrees>Ph.D.</degrees><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Vanderveken</surname><given-names>Olivier M.</given-names></name><degrees>M.D., Ph.D.</degrees><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib><aff id="aff1">Departments of<label>1</label>Special Care Dentistry, Antwerp University Hospital, Edegem, Antwerp, Belgium</aff><aff id="aff2"><label>2</label>Otolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium</aff><aff id="aff3"><label>3</label>Scientific Coordination and Biostatistics, Antwerp University Hospital, Edegem, Antwerp, Belgium</aff><aff id="aff4"><label>4</label>Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium</aff></contrib-group><author-notes><corresp id="cor1">Address correspondence to: Marijke Dieltjens, MBS, Drs., <addr-line>Special Care Dentistry, Antwerp University Hospital, Wilrijkstraat 10, BE-2650 Edegem, Belgium</addr-line><phone>+32 3 821 52 21</phone><fax>+32 3 821 42 71</fax><email>Marijke.Dieltjens@uza.be</email></corresp></author-notes><pub-date pub-type="epub"><day>15</day><month>9</month><year>2014</year></pub-date><volume>10</volume><issue>9</issue><fpage>959</fpage><lpage>964</lpage><history><date date-type="received"><month>8</month><year>2013</year></date><date date-type="rev-recd"><month>4</month><year>2014</year></date><date date-type="accepted"><month>4</month><year>2014</year></date></history><permissions><copyright-statement>© 2014 American Academy of Sleep Medicine</copyright-statement><copyright-year>2014</copyright-year></permissions><abstract><sec><title>Study Objective:</title><p>The prevalence of supine-dependent obstructive sleep apnea (sdOSA) in a general population ranges from 20% to 60%, depending on the criteria used. Currently, the prevalence and evolution of sdOSA once oral appliance therapy with a mandibular advancement device (OA<sub>m</sub>) has started is unknown. In addition, literature on the correlation between sdOSA and treatment success with OA<sub>m</sub> is not unequivocal. The first purpose of this study was to assess the prevalence of sdOSA before and under OA<sub>m</sub> therapy. Second, the conversion rate from non-sdOSA to sdOSA during OA<sub>m</sub> therapy was evaluated. The third and final goal was to analyze the correlation between sdOSA and treatment success with OA<sub>m</sub> therapy in the patient population.</p></sec><sec><title>Methods:</title><p>Two hundred thirty-seven consecutive patients (age 48 ± 9 years; male/female ratio 173/64; AHI 20.1 ± 14.7 events/h; BMI 27.2 ± 4.3 kg/m<sup>2</sup>) starting OA<sub>m</sub> therapy were included.</p></sec><sec><title>Results:</title><p>The prevalence of sdOSA before the start of OA<sub>m</sub> therapy, ranged from 27.0% to 67.5%. The prevalence of residual sdOSA under OA<sub>m</sub> therapy in this study ranged from 17.5% to 33.9%. Second, the conversion rate from non-sdOSA to sdOSA ranged from 23.0% to 37.5%. Third, the presence of sdOSA at baseline was not a significant factor for treatment success with OA<sub>m</sub> therapy.</p></sec><sec><title>Conclusions:</title><p>The results of this study indicate that the prevalence of sdOSA before and under OA<sub>m</sub> therapy is relatively high. One-third of patients shift from non-sdOSA to sdOSA. Finally, treatment success for OA<sub>m</sub> therapy was not significantly correlated with the presence of sdOSA at baseline.</p></sec><sec><title>Citation:</title><p>Dieltjens M, Braem MJ, Van de Heyning PH, Wouters K, Vanderveken OM. Prevalence and clinical significance of supine-dependent obstructive sleep apnea in patients using oral appliance therapy. <italic>J Clin Sleep Med</italic> 2014;10(9):959-964.</p></sec></abstract><kwd-group><kwd>oral appliance therapy</kwd><kwd>body position</kwd><kwd>prevalence</kwd><kwd>sleep disordered breathing</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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