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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Mastication Frequency and Postprandial Blood Sugar Levels in Normoglycaemic and Dysglycaemic Individuals: A Cross- Sectional Comparative Study</title><author><name sortKey="Madhu, Vinayak" sort="Madhu, Vinayak" uniqKey="Madhu V" first="Vinayak" last="Madhu">Vinayak Madhu</name><affiliation><nlm:aff id="aff1"> Junior Resident, Department of Medicine,<institution>Kasturba Medical College, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Shirali, Arun" sort="Shirali, Arun" uniqKey="Shirali A" first="Arun" last="Shirali">Arun Shirali</name><affiliation><nlm:aff id="aff2"> Associate Professor, Department of Medicine,<institution>Kasturba Medical College, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Pawaskar, Priyanka Niwas" sort="Pawaskar, Priyanka Niwas" uniqKey="Pawaskar P" first="Priyanka Niwas" last="Pawaskar">Priyanka Niwas Pawaskar</name><affiliation><nlm:aff id="aff3"> Assistant Professor, Department of Physiology,<institution>Kanachur Institute of Medical Sciences</institution>,<addr-line>Mangalore, India</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Madi, Deepak" sort="Madi, Deepak" uniqKey="Madi D" first="Deepak" last="Madi">Deepak Madi</name><affiliation><nlm:aff id="aff4"> Associate Professor, Department of Medicine,<institution>Kasturba Medical College, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Chowta, Nithyananda" sort="Chowta, Nithyananda" uniqKey="Chowta N" first="Nithyananda" last="Chowta">Nithyananda Chowta</name><affiliation><nlm:aff id="aff5"> Additional Professor, Department of Medicine,<institution>Kasturba Medical College, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Ramapuram, John Thomas" sort="Ramapuram, John Thomas" uniqKey="Ramapuram J" first="John Thomas" last="Ramapuram">John Thomas Ramapuram</name><affiliation><nlm:aff id="aff6"> Professor, Department of Medicine,<institution>Kasturba Medical College, Mangalore, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27630879</idno><idno type="pmc">5020307</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020307</idno><idno type="RBID">PMC:5020307</idno><idno type="doi">10.7860/JCDR/2016/18855.8082</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">002392</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002392</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Mastication Frequency and Postprandial Blood Sugar Levels in Normoglycaemic and Dysglycaemic Individuals: A Cross- Sectional Comparative Study</title><author><name sortKey="Madhu, Vinayak" sort="Madhu, Vinayak" uniqKey="Madhu V" first="Vinayak" last="Madhu">Vinayak Madhu</name><affiliation><nlm:aff id="aff1"> Junior Resident, Department of Medicine,<institution>Kasturba Medical College, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Shirali, Arun" sort="Shirali, Arun" uniqKey="Shirali A" first="Arun" last="Shirali">Arun Shirali</name><affiliation><nlm:aff id="aff2"> Associate Professor, Department of Medicine,<institution>Kasturba Medical College, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Pawaskar, Priyanka Niwas" sort="Pawaskar, Priyanka Niwas" uniqKey="Pawaskar P" first="Priyanka Niwas" last="Pawaskar">Priyanka Niwas Pawaskar</name><affiliation><nlm:aff id="aff3"> Assistant Professor, Department of Physiology,<institution>Kanachur Institute of Medical Sciences</institution>,<addr-line>Mangalore, India</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Madi, Deepak" sort="Madi, Deepak" uniqKey="Madi D" first="Deepak" last="Madi">Deepak Madi</name><affiliation><nlm:aff id="aff4"> Associate Professor, Department of Medicine,<institution>Kasturba Medical College, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Chowta, Nithyananda" sort="Chowta, Nithyananda" uniqKey="Chowta N" first="Nithyananda" last="Chowta">Nithyananda Chowta</name><affiliation><nlm:aff id="aff5"> Additional Professor, Department of Medicine,<institution>Kasturba Medical College, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Ramapuram, John Thomas" sort="Ramapuram, John Thomas" uniqKey="Ramapuram J" first="John Thomas" last="Ramapuram">John Thomas Ramapuram</name><affiliation><nlm:aff id="aff6"> Professor, Department of Medicine,<institution>Kasturba Medical College, Mangalore, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</nlm:aff></affiliation></author></analytic><series><title level="j">Journal of Clinical and Diagnostic Research : JCDR</title><idno type="ISSN">2249-782X</idno><idno type="eISSN">0973-709X</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Introduction</title><p>Mastication has potential to affect postprandial blood glucose levels by affecting cephalic phase of insulin release. However, limited number of studies done in this regard has yielded conflicting results.</p></sec><sec><title>Aim</title><p>To evaluate effects of mastication on postprandial blood glucose levels.</p></sec><sec><title>Materials and Methods</title><p>We compared routine and thorough mastication in 2 separate groups: dysglycaemic (prediabetics and diabetics) and normoglycaemic in prospective interventional study. Blood glucose levels were measured pre-prandial and postprandial (after 2 hours) on separate days after routine and thorough mastication in both groups.</p></sec><sec><title>Results</title><p>In normoglycaemic group, thorough mastication significantly reduced postprandial blood glucose levels at 2 hours (128.25± 7.82 mg/dl on routine mastication vs 119.74±9.08 mg/dl on thorough mastication, p<0.05). Comparatively, in dysglycaemic group, thorough mastication had little effect on postprandial blood glucose levels at 2 hours (244.07±22.37 mg/dl vs. 243.55±22.87 mg/dl).</p></sec><sec><title>Conclusion</title><p>In normoglycaemic group, postprandial blood glucose concentration upon thorough mastication was significantly lower, due to early-phase insulin secretion. This simple lifestyle modification of thorough mastication can be a useful preventive measure against diabetes in people with a strong family history and other risk factors for diabetes who have not yet developed diabetes or prediabetes.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Clin Diagn Res</journal-id><journal-id journal-id-type="iso-abbrev">J Clin Diagn Res</journal-id><journal-id journal-id-type="hwp">Journal of Clinical and Diagnostic Research</journal-id><journal-id journal-id-type="publisher-id">JCDR</journal-id><journal-title-group><journal-title>Journal of Clinical and Diagnostic Research : JCDR</journal-title></journal-title-group><issn pub-type="ppub">2249-782X</issn><issn pub-type="epub">0973-709X</issn><publisher><publisher-name>JCDR Research and Publications (P) Limited</publisher-name><publisher-loc>Delhi, India</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27630879</article-id><article-id pub-id-type="pmc">5020307</article-id><article-id pub-id-type="doi">10.7860/JCDR/2016/18855.8082</article-id><article-categories><subj-group subj-group-type="heading"><subject>Internal Medicine Section</subject><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></subj-group></article-categories><title-group><article-title>Mastication Frequency and Postprandial Blood Sugar Levels in Normoglycaemic and Dysglycaemic Individuals: A Cross- Sectional Comparative Study</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Madhu</surname><given-names>Vinayak</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Shirali</surname><given-names>Arun</given-names></name><xref ref-type="aff" rid="aff2">2</xref><xref ref-type="corresp" rid="cor1"></xref></contrib><contrib contrib-type="author"><name><surname>Pawaskar</surname><given-names>Priyanka Niwas</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Madi</surname><given-names>Deepak</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Chowta</surname><given-names>Nithyananda</given-names></name><xref ref-type="aff" rid="aff5">5</xref></contrib><contrib contrib-type="author"><name><surname>Ramapuram</surname><given-names>John Thomas</given-names></name><xref ref-type="aff" rid="aff6">6</xref></contrib></contrib-group><aff id="aff1"><label>1</label> Junior Resident, Department of Medicine,<institution>Kasturba Medical College, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</aff><aff id="aff2"><label>2</label> Associate Professor, Department of Medicine,<institution>Kasturba Medical College, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</aff><aff id="aff3"><label>3</label> Assistant Professor, Department of Physiology,<institution>Kanachur Institute of Medical Sciences</institution>,<addr-line>Mangalore, India</addr-line>.</aff><aff id="aff4"><label>4</label> Associate Professor, Department of Medicine,<institution>Kasturba Medical College, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</aff><aff id="aff5"><label>5</label> Additional Professor, Department of Medicine,<institution>Kasturba Medical College, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</aff><aff id="aff6"><label>6</label> Professor, Department of Medicine,<institution>Kasturba Medical College, Mangalore, Manipal University</institution>,<addr-line>Mangalore, India</addr-line>.</aff><author-notes><corresp id="cor1">NAME, ADDRESS, E-MAIL ID OF THE CORRESPONDING AUTHOR: Dr. Arun Shirali, Associate Professor, Department of Internal Medicine, KMC – Attavar, Manipal University, Mangalore, India. E-mail: <email>drarunshirali@gmail.com</email></corresp></author-notes><pub-date pub-type="ppub"><month>7</month><year>2016</year></pub-date><pub-date pub-type="epub"><day>01</day><month>7</month><year>2016</year></pub-date><volume>10</volume><issue>7</issue><fpage>OC06</fpage><lpage>OC08</lpage><history><date date-type="received"><day>13</day><month>1</month><year>2016</year></date><date date-type="rev-request"><day>29</day><month>2</month><year>2016</year></date><date date-type="accepted"><day>26</day><month>3</month><year>2016</year></date></history><permissions><copyright-statement>© 2016 Journal of Clinical and Diagnostic Research</copyright-statement><copyright-year>2016</copyright-year></permissions><abstract><sec><title>Introduction</title><p>Mastication has potential to affect postprandial blood glucose levels by affecting cephalic phase of insulin release. However, limited number of studies done in this regard has yielded conflicting results.</p></sec><sec><title>Aim</title><p>To evaluate effects of mastication on postprandial blood glucose levels.</p></sec><sec><title>Materials and Methods</title><p>We compared routine and thorough mastication in 2 separate groups: dysglycaemic (prediabetics and diabetics) and normoglycaemic in prospective interventional study. Blood glucose levels were measured pre-prandial and postprandial (after 2 hours) on separate days after routine and thorough mastication in both groups.</p></sec><sec><title>Results</title><p>In normoglycaemic group, thorough mastication significantly reduced postprandial blood glucose levels at 2 hours (128.25± 7.82 mg/dl on routine mastication vs 119.74±9.08 mg/dl on thorough mastication, p<0.05). Comparatively, in dysglycaemic group, thorough mastication had little effect on postprandial blood glucose levels at 2 hours (244.07±22.37 mg/dl vs. 243.55±22.87 mg/dl).</p></sec><sec><title>Conclusion</title><p>In normoglycaemic group, postprandial blood glucose concentration upon thorough mastication was significantly lower, due to early-phase insulin secretion. This simple lifestyle modification of thorough mastication can be a useful preventive measure against diabetes in people with a strong family history and other risk factors for diabetes who have not yet developed diabetes or prediabetes.</p></sec></abstract><kwd-group><kwd>Diabetics</kwd><kwd>Plasma glucose levels</kwd><kwd>Pre-diabetics</kwd><kwd>Rate of chewing</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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