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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Re-stability of dental implants following treatment of
peri-implantitis</title>
<author><name sortKey="Javed, Fawad" sort="Javed, Fawad" uniqKey="Javed F" first="Fawad" last="Javed">Fawad Javed</name>
<affiliation><nlm:aff id="A1"><institution>Eng. A.B. Research Chair for Growth Factors and Bone Regeneration, 3D Imaging and Biomechanical Laboratory, College of Applied Medical Sciences, King Saud University</institution>
<addr-line>Riyadh</addr-line>
<country>Saudi Arabia</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hussain, Hamza Ather" sort="Hussain, Hamza Ather" uniqKey="Hussain H" first="Hamza Ather" last="Hussain">Hamza Ather Hussain</name>
<affiliation><nlm:aff id="A2"><institution>Department of Dentistry, Liaquat National Hospital</institution>
<addr-line>Karachi</addr-line>
<country>Pakistan</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Romanos, Georgios E" sort="Romanos, Georgios E" uniqKey="Romanos G" first="Georgios E." last="Romanos">Georgios E. Romanos</name>
<affiliation><nlm:aff id="A3"><institution>School of Dental Medicine, Stony Brook University</institution>
<addr-line>Stony Brook, NY</addr-line>
<country>USA</country>
</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24265901</idno>
<idno type="pmc">3831812</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831812</idno>
<idno type="RBID">PMC:3831812</idno>
<idno type="doi">10.1556/IMAS.5.2013.3.4</idno>
<date when="2013">2013</date>
<idno type="wicri:Area/Pmc/Corpus">002347</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002347</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Re-stability of dental implants following treatment of
peri-implantitis</title>
<author><name sortKey="Javed, Fawad" sort="Javed, Fawad" uniqKey="Javed F" first="Fawad" last="Javed">Fawad Javed</name>
<affiliation><nlm:aff id="A1"><institution>Eng. A.B. Research Chair for Growth Factors and Bone Regeneration, 3D Imaging and Biomechanical Laboratory, College of Applied Medical Sciences, King Saud University</institution>
<addr-line>Riyadh</addr-line>
<country>Saudi Arabia</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hussain, Hamza Ather" sort="Hussain, Hamza Ather" uniqKey="Hussain H" first="Hamza Ather" last="Hussain">Hamza Ather Hussain</name>
<affiliation><nlm:aff id="A2"><institution>Department of Dentistry, Liaquat National Hospital</institution>
<addr-line>Karachi</addr-line>
<country>Pakistan</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Romanos, Georgios E" sort="Romanos, Georgios E" uniqKey="Romanos G" first="Georgios E." last="Romanos">Georgios E. Romanos</name>
<affiliation><nlm:aff id="A3"><institution>School of Dental Medicine, Stony Brook University</institution>
<addr-line>Stony Brook, NY</addr-line>
<country>USA</country>
</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Interventional Medicine & Applied Science</title>
<idno type="ISSN">2061-1617</idno>
<idno type="eISSN">2061-5094</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>It is hypothesized that active treatment of peri-implantitis (PI) leads to
re-stabilization of dental implants. The aim was to assess whether or not dental
implants can re-stabilize following treatment of PI. To address the focused
question, MEDLINE/PubMed and Google-Scholar databases were explored from 1977 up
to and including August 2013. Any disagreements between the authors were
resolved via discussion. Articles published only in English were included. Hand
searching was also performed. Thirteen experimental studies were included. The
treatment regimes adopted in these studies comprised of antibiotic therapy,
guided bone regeneration (GBR), laser therapy, use of bone matrix proteins with
membrane, conventional flap surgery and mechanical debridement. In four studies,
GBR promoted new bone formation; whereas two studies showed photosensitization
therapy (in combination with either mechanical debridement or GBR) to regenerate
bone around peri-implant defects. Six studies reported that mechanical
debridement in conjunction with antibiotic therapy promoted re-stability of
dental implants. In one study, recombinant human bone matrix protein-2 with a
collagen membrane helped promote re-stabilization of dental implants. New bone
formation may occur to some extent around dental implants following treatment
for PI; however, a “complete” re-stability may be difficult to achieve without
GBR.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Interv Med Appl Sci</journal-id>
<journal-id journal-id-type="iso-abbrev">Interv Med Appl Sci</journal-id>
<journal-id journal-id-type="publisher-id">IMAS</journal-id>
<journal-title-group><journal-title>Interventional Medicine & Applied Science</journal-title>
</journal-title-group>
<issn pub-type="ppub">2061-1617</issn>
<issn pub-type="epub">2061-5094</issn>
<publisher><publisher-name>Akadémiai Kiadó</publisher-name>
<publisher-loc>journals@akkrt.huhttp://www.akademiaikiado.hu</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">24265901</article-id>
<article-id pub-id-type="pmc">3831812</article-id>
<article-id pub-id-type="publisher-id">IMAS_5(2013)3/4</article-id>
<article-id pub-id-type="doi">10.1556/IMAS.5.2013.3.4</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Review</subject>
</subj-group>
<subj-group subj-group-type="Medicine"><subject>Hematology, Cancer and Oncology, Gastroenterology and Hepatology, Nephrology and Urology, Pediatrics, Surgery, Medical Research, Clinical Medicine and Cardiovascular and Respiratory Systems</subject>
</subj-group>
</article-categories>
<title-group><article-title>Re-stability of dental implants following treatment of
peri-implantitis</article-title>
</title-group>
<contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Javed</surname>
<given-names>Fawad</given-names>
</name>
<xref ref-type="aff" rid="A1"><sup>1</sup>
</xref>
<xref ref-type="author-notes" rid="FN1"><sup>*</sup>
</xref>
<aff><sup>1</sup>
<institution>Eng. A.B. Research Chair for Growth Factors and Bone Regeneration, 3D Imaging and Biomechanical Laboratory, College of Applied Medical Sciences, King Saud University</institution>
<addr-line>Riyadh</addr-line>
<country>Saudi Arabia</country>
</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Hussain</surname>
<given-names>Hamza Ather</given-names>
</name>
<xref ref-type="aff" rid="A2"><sup>2</sup>
</xref>
<aff><sup>2</sup>
<institution>Department of Dentistry, Liaquat National Hospital</institution>
<addr-line>Karachi</addr-line>
<country>Pakistan</country>
</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Romanos</surname>
<given-names>Georgios E.</given-names>
</name>
<xref ref-type="aff" rid="A3"><sup>3</sup>
</xref>
<aff><sup>3</sup>
<institution>School of Dental Medicine, Stony Brook University</institution>
<addr-line>Stony Brook, NY</addr-line>
<country>USA</country>
</aff>
</contrib>
</contrib-group>
<aff id="A1"><sup>1</sup>
<institution>Eng. A.B. Research Chair for Growth Factors and Bone Regeneration, 3D Imaging and Biomechanical Laboratory, College of Applied Medical Sciences, King Saud University</institution>
<addr-line>Riyadh</addr-line>
<country>Saudi Arabia</country>
</aff>
<aff id="A2"><sup>2</sup>
<institution>Department of Dentistry, Liaquat National Hospital</institution>
<addr-line>Karachi</addr-line>
<country>Pakistan</country>
</aff>
<aff id="A3"><sup>3</sup>
<institution>School of Dental Medicine, Stony Brook University</institution>
<addr-line>Stony Brook, NY</addr-line>
<country>USA</country>
</aff>
<author-notes><fn id="FN1"><p><sup>*</sup>
Corresponding author: Dr. Fawad Javed; Eng. A. B. Research Chair
for Growth Factors and Bone Regeneration, 3D Imaging and Biomechanical
Laboratory, College of Applied Medical Sciences, King Saud University,
Riyadh, Saudi Arabia; Phone: +966 50 968 6358; E-mail: fawjav@gmail.com</p>
</fn>
</author-notes>
<pub-date pub-type="ppub"><month>9</month>
<year>2013</year>
</pub-date>
<pub-date pub-type="epub"><day>16</day>
<month>9</month>
<year>2013</year>
</pub-date>
<volume>5</volume>
<issue>3</issue>
<fpage>116</fpage>
<lpage>121</lpage>
<history><date date-type="received"><day>29</day>
<month>6</month>
<year>2013</year>
</date>
<date date-type="rev-recd"><day>4</day>
<month>8</month>
<year>2013</year>
</date>
<date date-type="accepted"><day>5</day>
<month>8</month>
<year>2013</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2013, Akadémiai Kiadó,
Budapest</copyright-statement>
<copyright-year>2013</copyright-year>
</permissions>
<abstract><p>It is hypothesized that active treatment of peri-implantitis (PI) leads to
re-stabilization of dental implants. The aim was to assess whether or not dental
implants can re-stabilize following treatment of PI. To address the focused
question, MEDLINE/PubMed and Google-Scholar databases were explored from 1977 up
to and including August 2013. Any disagreements between the authors were
resolved via discussion. Articles published only in English were included. Hand
searching was also performed. Thirteen experimental studies were included. The
treatment regimes adopted in these studies comprised of antibiotic therapy,
guided bone regeneration (GBR), laser therapy, use of bone matrix proteins with
membrane, conventional flap surgery and mechanical debridement. In four studies,
GBR promoted new bone formation; whereas two studies showed photosensitization
therapy (in combination with either mechanical debridement or GBR) to regenerate
bone around peri-implant defects. Six studies reported that mechanical
debridement in conjunction with antibiotic therapy promoted re-stability of
dental implants. In one study, recombinant human bone matrix protein-2 with a
collagen membrane helped promote re-stabilization of dental implants. New bone
formation may occur to some extent around dental implants following treatment
for PI; however, a “complete” re-stability may be difficult to achieve without
GBR.</p>
</abstract>
<kwd-group kwd-group-type="simple"><title>Keywords</title>
<kwd>dental implants</kwd>
<kwd>osseointegration</kwd>
<kwd>peri-implantitis</kwd>
<kwd>treatment</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
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