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Laser micro-grooved, Arginine-Glycine-Apspartic acid (RGD) coated dental implants, a 5 years radiographic follow-up

Identifieur interne : 002344 ( Pmc/Corpus ); précédent : 002343; suivant : 002345

Laser micro-grooved, Arginine-Glycine-Apspartic acid (RGD) coated dental implants, a 5 years radiographic follow-up

Auteurs : Mohamed Ahmed Alkhodary

Source :

RBID : PMC:4350890

Abstract

Objectives

This work has utilized laser direct writing to produce 10 microns wide uniform grooves on the surface of custom made titanium (Ti-6Al-4V) dental implants, and the tri-peptide RGD coating to produce a micromechanical and a chemical union with the tissues around the implant crest module and minimize crestal bone loss. The aim of this study was to follow these implants radiographically after five years of service under a mandibular overdenture.

Methodology

Standardized digital periapical radiographs and the computer software “Image J” were used to evaluate the bone density profile and vertical bone loss along the mesial and distal sides of the implants used in this study.

Results

The results of this study demonstrated less vertical bone loss and higher bone density profiles next to the laser microgrooved implants coated with the RGD than those only having the laser micro-grooves.

Conclusion

The RGD coating has improved the bone density profile and reduced the vertical bone loss around the studied dental implants. However, further studies are needed to compare the effects of the laser micro-grooves versus other uniform or non uniform surface features; also, the RGD coating should be compared to other biomimetic surface coating materials.


Url:
PubMed: 25780355
PubMed Central: 4350890

Links to Exploration step

PMC:4350890

Le document en format XML

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<title>Objectives</title>
<p>This work has utilized laser direct writing to produce 10 microns wide uniform grooves on the surface of custom made titanium (Ti-6Al-4V) dental implants, and the tri-peptide RGD coating to produce a micromechanical and a chemical union with the tissues around the implant crest module and minimize crestal bone loss. The aim of this study was to follow these implants radiographically after five years of service under a mandibular overdenture.</p>
</sec>
<sec>
<title>Methodology</title>
<p>Standardized digital periapical radiographs and the computer software “Image J” were used to evaluate the bone density profile and vertical bone loss along the mesial and distal sides of the implants used in this study.</p>
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<sec>
<title>Results</title>
<p>The results of this study demonstrated less vertical bone loss and higher bone density profiles next to the laser microgrooved implants coated with the RGD than those only having the laser micro-grooves.</p>
</sec>
<sec>
<title>Conclusion</title>
<p>The RGD coating has improved the bone density profile and reduced the vertical bone loss around the studied dental implants. However, further studies are needed to compare the effects of the laser micro-grooves versus other uniform or non uniform surface features; also, the RGD coating should be compared to other biomimetic surface coating materials.</p>
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<given-names>Mohamed Ahmed</given-names>
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<degrees>BDS, MS, PhD</degrees>
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<aff id="af1-ijhs-8-4-361">Lecturer of Removable Prosthodontics, Faculty of Dentistry, Alexandria University, Egypt, Assistant Professor of Prosthetic Dental Science, College of Dentistry, Al Qassim University, KSA.</aff>
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<author-notes>
<corresp id="c1-ijhs-8-4-361">Correspondence: Mohamed A. Alkhodary BDS, MS, PhD, Head of the Faculty Development Unit, Assistant Professor of Prosthetic Dental Science, Board Member, Dental Research Center, College of Dentistry, Al Qassim University, KSA., Lecturer, Faculty of Dentistry, Alexandria University, EGYPT., Visiting Graduate Fellow, MAE dept, Princeton University, USA., Phone: 00966 538950814, Email:
<email>dr.mohamed.alkhodary@qudent.org</email>
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<pub-date pub-type="ppub">
<month>10</month>
<year>2014</year>
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<volume>8</volume>
<issue>4</issue>
<fpage>361</fpage>
<lpage>369</lpage>
<permissions>
<copyright-statement>Copyright Qassim University</copyright-statement>
<copyright-year>2014</copyright-year>
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<abstract>
<sec>
<title>Objectives</title>
<p>This work has utilized laser direct writing to produce 10 microns wide uniform grooves on the surface of custom made titanium (Ti-6Al-4V) dental implants, and the tri-peptide RGD coating to produce a micromechanical and a chemical union with the tissues around the implant crest module and minimize crestal bone loss. The aim of this study was to follow these implants radiographically after five years of service under a mandibular overdenture.</p>
</sec>
<sec>
<title>Methodology</title>
<p>Standardized digital periapical radiographs and the computer software “Image J” were used to evaluate the bone density profile and vertical bone loss along the mesial and distal sides of the implants used in this study.</p>
</sec>
<sec>
<title>Results</title>
<p>The results of this study demonstrated less vertical bone loss and higher bone density profiles next to the laser microgrooved implants coated with the RGD than those only having the laser micro-grooves.</p>
</sec>
<sec>
<title>Conclusion</title>
<p>The RGD coating has improved the bone density profile and reduced the vertical bone loss around the studied dental implants. However, further studies are needed to compare the effects of the laser micro-grooves versus other uniform or non uniform surface features; also, the RGD coating should be compared to other biomimetic surface coating materials.</p>
</sec>
</abstract>
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<kwd>RGD</kwd>
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