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<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Volumetric difference evaluation of registered three-dimensional pre-operative and post-operative CT dental data</title>
<author>
<name sortKey="Economopoulos, Tl" sort="Economopoulos, Tl" uniqKey="Economopoulos T" first="Tl" last="Economopoulos">Tl Economopoulos</name>
<affiliation>
<nlm:aff id="aff1">
<addr-line>School of Electrical and Computer Engineering, National Technical University of Athens, Greece</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Asvestas, Pa" sort="Asvestas, Pa" uniqKey="Asvestas P" first="Pa" last="Asvestas">Pa Asvestas</name>
<affiliation>
<nlm:aff id="aff2">
<addr-line>Department of Medical Instruments Technology, Technological Educational Institute of Athens, Greece</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Matsopoulos, Gk" sort="Matsopoulos, Gk" uniqKey="Matsopoulos G" first="Gk" last="Matsopoulos">Gk Matsopoulos</name>
<affiliation>
<nlm:aff id="aff1">
<addr-line>School of Electrical and Computer Engineering, National Technical University of Athens, Greece</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Molnar, B" sort="Molnar, B" uniqKey="Molnar B" first="B" last="Molnár">B. Molnár</name>
<affiliation>
<nlm:aff id="aff3">
<addr-line>Department of Periodontology, Semmelweis University, Budapest</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Windisch, P" sort="Windisch, P" uniqKey="Windisch P" first="P" last="Windisch">P. Windisch</name>
<affiliation>
<nlm:aff id="aff3">
<addr-line>Department of Periodontology, Semmelweis University, Budapest</addr-line>
</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PMC</idno>
<idno type="pmid">22241879</idno>
<idno type="pmc">3728999</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728999</idno>
<idno type="RBID">PMC:3728999</idno>
<idno type="doi">10.1259/dmfr/94040044</idno>
<date when="2012">2012</date>
<idno type="wicri:Area/Pmc/Corpus">002298</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002298</idno>
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<analytic>
<title xml:lang="en" level="a" type="main">Volumetric difference evaluation of registered three-dimensional pre-operative and post-operative CT dental data</title>
<author>
<name sortKey="Economopoulos, Tl" sort="Economopoulos, Tl" uniqKey="Economopoulos T" first="Tl" last="Economopoulos">Tl Economopoulos</name>
<affiliation>
<nlm:aff id="aff1">
<addr-line>School of Electrical and Computer Engineering, National Technical University of Athens, Greece</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Asvestas, Pa" sort="Asvestas, Pa" uniqKey="Asvestas P" first="Pa" last="Asvestas">Pa Asvestas</name>
<affiliation>
<nlm:aff id="aff2">
<addr-line>Department of Medical Instruments Technology, Technological Educational Institute of Athens, Greece</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Matsopoulos, Gk" sort="Matsopoulos, Gk" uniqKey="Matsopoulos G" first="Gk" last="Matsopoulos">Gk Matsopoulos</name>
<affiliation>
<nlm:aff id="aff1">
<addr-line>School of Electrical and Computer Engineering, National Technical University of Athens, Greece</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Molnar, B" sort="Molnar, B" uniqKey="Molnar B" first="B" last="Molnár">B. Molnár</name>
<affiliation>
<nlm:aff id="aff3">
<addr-line>Department of Periodontology, Semmelweis University, Budapest</addr-line>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Windisch, P" sort="Windisch, P" uniqKey="Windisch P" first="P" last="Windisch">P. Windisch</name>
<affiliation>
<nlm:aff id="aff3">
<addr-line>Department of Periodontology, Semmelweis University, Budapest</addr-line>
</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Dentomaxillofacial Radiology</title>
<idno type="ISSN">0250-832X</idno>
<idno type="eISSN">1476-542X</idno>
<imprint>
<date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
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<front>
<div type="abstract" xml:lang="en">
<p>
<bold>Objective:</bold>
The purpose of this study is to propose a complete methodology for automatically registering three-dimensional (3D) pre-operative and post-operative CT scan dental volumes as well as to provide a toolset for quantifying and evaluating their volumetric differences.</p>
<p>
<bold>Methods:</bold>
The proposed methodology was applied to cone beam CT (CBCT) data from 20 patients in order to assess the volume of augmented bone in the alveolar region. In each case, the pre-operative and post-operative data were registered using a 3D affine-based scheme. The performance of the 3D registration algorithm was evaluated by measuring the average distance between the edges of the registered sets. The differences between the registered sets were assessed through 3D subtraction radiography. The volume of the differences was finally evaluated by defining regions of interest in each slice of the subtracted 3D data and by combining all respective slices to model the desired volume of interest. The effectiveness of the algorithm was verified by applying it to several reference standard-shaped objects with known volumes.</p>
<p>
<bold>Results:</bold>
Satisfactory alignment was achieved as a low average offset of 1.483 ± 1.558 mm was recorded between the edges of the registered sets. Moreover, the estimated volumes closely matched the volumes of the reference objects used for verification, as the recorded volume differences were less than 0.4 mm
<sup>3</sup>
in all cases.</p>
<p>
<bold>Conclusion:</bold>
The proposed method allows for automatic registration of 3D CBCT data sets and the volumetric assessment of their differences in particular areas of interest. The proposed approach provides accurate volumetric measurements in three dimensions, requiring minimal user interaction.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Dentomaxillofac Radiol</journal-id>
<journal-id journal-id-type="iso-abbrev">Dentomaxillofac Radiol</journal-id>
<journal-id journal-id-type="hwp">dmfr</journal-id>
<journal-id journal-id-type="publisher-id">dmf</journal-id>
<journal-title-group>
<journal-title>Dentomaxillofacial Radiology</journal-title>
</journal-title-group>
<issn pub-type="ppub">0250-832X</issn>
<issn pub-type="epub">1476-542X</issn>
<publisher>
<publisher-name>The British Institute of Radiology.</publisher-name>
<publisher-loc>36 Portland Place, London, W1B 1AT</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">22241879</article-id>
<article-id pub-id-type="pmc">3728999</article-id>
<article-id pub-id-type="publisher-id">D11054</article-id>
<article-id pub-id-type="doi">10.1259/dmfr/94040044</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Technical Report</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Volumetric difference evaluation of registered three-dimensional pre-operative and post-operative CT dental data</article-title>
<alt-title alt-title-type="running-head">Volumetric difference evaluation</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Economopoulos</surname>
<given-names>TL</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Asvestas</surname>
<given-names>PA</given-names>
</name>
<xref ref-type="aff" rid="aff2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Matsopoulos</surname>
<given-names>GK</given-names>
</name>
<xref ref-type="corresp" rid="cor1">*</xref>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Molnár</surname>
<given-names>B</given-names>
</name>
<xref ref-type="aff" rid="aff3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Windisch</surname>
<given-names>P</given-names>
</name>
<xref ref-type="aff" rid="aff3">3</xref>
</contrib>
</contrib-group>
<aff id="aff1">
<label>1</label>
<addr-line>School of Electrical and Computer Engineering, National Technical University of Athens, Greece</addr-line>
</aff>
<aff id="aff2">
<label>2</label>
<addr-line>Department of Medical Instruments Technology, Technological Educational Institute of Athens, Greece</addr-line>
</aff>
<aff id="aff3">
<label>3</label>
<addr-line>Department of Periodontology, Semmelweis University, Budapest</addr-line>
</aff>
<author-notes>
<corresp id="cor1">Professor George K Matsopoulos, 9, Iroon Polytechniou str, Zografos, 15780 Athens, Greece. E-mail:
<email>gmatso@esd.ece.ntua.gr</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>5</month>
<year>2012</year>
</pub-date>
<volume>41</volume>
<issue>4</issue>
<fpage>328</fpage>
<lpage>339</lpage>
<history>
<date date-type="received">
<day>14</day>
<month>2</month>
<year>2011</year>
</date>
<date date-type="rev-recd">
<day>30</day>
<month>5</month>
<year>2011</year>
</date>
<date date-type="accepted">
<day>31</day>
<month>5</month>
<year>2011</year>
</date>
</history>
<permissions>
<copyright-statement>2012 The British Institute of Radiology</copyright-statement>
<copyright-year>2012</copyright-year>
</permissions>
<abstract>
<p>
<bold>Objective:</bold>
The purpose of this study is to propose a complete methodology for automatically registering three-dimensional (3D) pre-operative and post-operative CT scan dental volumes as well as to provide a toolset for quantifying and evaluating their volumetric differences.</p>
<p>
<bold>Methods:</bold>
The proposed methodology was applied to cone beam CT (CBCT) data from 20 patients in order to assess the volume of augmented bone in the alveolar region. In each case, the pre-operative and post-operative data were registered using a 3D affine-based scheme. The performance of the 3D registration algorithm was evaluated by measuring the average distance between the edges of the registered sets. The differences between the registered sets were assessed through 3D subtraction radiography. The volume of the differences was finally evaluated by defining regions of interest in each slice of the subtracted 3D data and by combining all respective slices to model the desired volume of interest. The effectiveness of the algorithm was verified by applying it to several reference standard-shaped objects with known volumes.</p>
<p>
<bold>Results:</bold>
Satisfactory alignment was achieved as a low average offset of 1.483 ± 1.558 mm was recorded between the edges of the registered sets. Moreover, the estimated volumes closely matched the volumes of the reference objects used for verification, as the recorded volume differences were less than 0.4 mm
<sup>3</sup>
in all cases.</p>
<p>
<bold>Conclusion:</bold>
The proposed method allows for automatic registration of 3D CBCT data sets and the volumetric assessment of their differences in particular areas of interest. The proposed approach provides accurate volumetric measurements in three dimensions, requiring minimal user interaction.</p>
</abstract>
<kwd-group>
<kwd>computer-assisted image processing</kwd>
<kwd>digital subtraction radiography</kwd>
<kwd>volumetric computed tomography</kwd>
<kwd>alveolar ridge augmentation</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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