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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A Prospective Study of Early Loaded Single Implant-Retained Mandibular Overdentures: Preliminary One-Year Results</title><author><name sortKey="El Sheikh, Ali M" sort="El Sheikh, Ali M" uniqKey="El Sheikh A" first="Ali M." last="El-Sheikh">Ali M. El-Sheikh</name><affiliation><nlm:aff id="I1">Department of Prosthetic Dentistry, Faculty of Dentistry, Tanta University, Tanta 31111, Egypt</nlm:aff></affiliation></author><author><name sortKey="Shihabuddin, Omar F" sort="Shihabuddin, Omar F" uniqKey="Shihabuddin O" first="Omar F." last="Shihabuddin">Omar F. Shihabuddin</name><affiliation><nlm:aff id="I2">Department of Oral Maxillofacial Surgery, Dammam Dental Centre, Dammam Medical Complex, Dammam 31433, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Ghoraba, Sahar M F" sort="Ghoraba, Sahar M F" uniqKey="Ghoraba S" first="Sahar M. F." last="Ghoraba">Sahar M. F. Ghoraba</name><affiliation><nlm:aff id="I3">Department of Oral Medicine, Periodontology, Radiology and Diagnosis, Faculty of Dentistry, Tanta University, Tanta 31111, Egypt</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22505895</idno><idno type="pmc">3312253</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312253</idno><idno type="RBID">PMC:3312253</idno><idno type="doi">10.1155/2012/236409</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">002048</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002048</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A Prospective Study of Early Loaded Single Implant-Retained Mandibular Overdentures: Preliminary One-Year Results</title><author><name sortKey="El Sheikh, Ali M" sort="El Sheikh, Ali M" uniqKey="El Sheikh A" first="Ali M." last="El-Sheikh">Ali M. El-Sheikh</name><affiliation><nlm:aff id="I1">Department of Prosthetic Dentistry, Faculty of Dentistry, Tanta University, Tanta 31111, Egypt</nlm:aff></affiliation></author><author><name sortKey="Shihabuddin, Omar F" sort="Shihabuddin, Omar F" uniqKey="Shihabuddin O" first="Omar F." last="Shihabuddin">Omar F. Shihabuddin</name><affiliation><nlm:aff id="I2">Department of Oral Maxillofacial Surgery, Dammam Dental Centre, Dammam Medical Complex, Dammam 31433, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Ghoraba, Sahar M F" sort="Ghoraba, Sahar M F" uniqKey="Ghoraba S" first="Sahar M. F." last="Ghoraba">Sahar M. F. Ghoraba</name><affiliation><nlm:aff id="I3">Department of Oral Medicine, Periodontology, Radiology and Diagnosis, Faculty of Dentistry, Tanta University, Tanta 31111, Egypt</nlm:aff></affiliation></author></analytic><series><title level="j">International Journal of Dentistry</title><idno type="ISSN">1687-8728</idno><idno type="eISSN">1687-8736</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><italic>Purpose.</italic> To investigate the predictability of simplifying mandibular overdenture treatment using one-stage surgery and early prosthetic loading of a single implant. <italic>Materials and Methods.</italic> Twenty edentulous patients with problematic existing mandibular dentures were treated. A single implant with a chemically modified surface (SLActive, Straumann AG, Basel, Switzerland) was placed into the mandibular midline. The patients were recalled at 3, 6 and 12 months. Clinical assessments and marginal bone loss using standardized radiographs were recorded. All complications, failures and maintenance were noted. Visual analog-scale questionnaires were used to record patient satisfaction in five categories. ANOVA was used to determine differences between means of marginal bone loss and different categories of patient staisfaction (<italic>P</italic> = 0.05). <italic>Results.</italic> The 20 early loaded implants were all surviving at the 12-month recall. All implants showed less than 1 mm of marginal bone loss by the end of the 1-year with a significant increase during the follow-up period. Few prosthetic problems were reported. Patient satisfaction was high with a significant increase in all comfort and functional parameters. <italic>Conclusions.</italic> These preliminary 1-year results indicate that early loading of a single chemically modified surface implant used to retain a mucosa-borne mandibular overdenture is a safe, reliable, and cost-effective treatment.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Adell, R" uniqKey="Adell R">R Adell</name></author><author><name sortKey="Lekholm, U" uniqKey="Lekholm U">U Lekholm</name></author><author><name sortKey="Rockler, B" uniqKey="Rockler B">B Rockler</name></author><author><name sortKey="Br Nemark, Pi" uniqKey="Br Nemark P">PI Brånemark</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Petersson, A" uniqKey="Petersson A">A Petersson</name></author><author><name sortKey="Rangert, B" uniqKey="Rangert B">B Rangert</name></author><author><name sortKey="Randow, K" 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Int J Dent</journal-id><journal-id journal-id-type="iso-abbrev">Int J Dent</journal-id><journal-id journal-id-type="publisher-id">IJD</journal-id><journal-title-group><journal-title>International Journal of Dentistry</journal-title></journal-title-group><issn pub-type="ppub">1687-8728</issn><issn pub-type="epub">1687-8736</issn><publisher><publisher-name>Hindawi Publishing Corporation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">22505895</article-id><article-id pub-id-type="pmc">3312253</article-id><article-id pub-id-type="doi">10.1155/2012/236409</article-id><article-categories><subj-group subj-group-type="heading"><subject>Clinical Study</subject></subj-group></article-categories><title-group><article-title>A Prospective Study of Early Loaded Single Implant-Retained Mandibular Overdentures: Preliminary One-Year Results</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>El-Sheikh</surname><given-names>Ali M.</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Shihabuddin</surname><given-names>Omar F.</given-names></name><xref ref-type="aff" rid="I2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Ghoraba</surname><given-names>Sahar M. F.</given-names></name><xref ref-type="aff" rid="I3"><sup>3</sup></xref></contrib></contrib-group><aff id="I1"><sup>1</sup>Department of Prosthetic Dentistry, Faculty of Dentistry, Tanta University, Tanta 31111, Egypt</aff><aff id="I2"><sup>2</sup>Department of Oral Maxillofacial Surgery, Dammam Dental Centre, Dammam Medical Complex, Dammam 31433, Saudi Arabia</aff><aff id="I3"><sup>3</sup>Department of Oral Medicine, Periodontology, Radiology and Diagnosis, Faculty of Dentistry, Tanta University, Tanta 31111, Egypt</aff><author-notes><corresp id="cor1">*Ali M. El-Sheikh: <email>aliel-sheikh@hotmail.com</email></corresp><fn fn-type="other"><p>Academic Editor: Dimitris N. Tatakis</p></fn></author-notes><pub-date pub-type="ppub"><year>2012</year></pub-date><pub-date pub-type="epub"><day>15</day><month>3</month><year>2012</year></pub-date><volume>2012</volume><elocation-id>236409</elocation-id><history><date date-type="received"><day>24</day><month>10</month><year>2011</year></date><date date-type="rev-recd"><day>17</day><month>12</month><year>2011</year></date><date date-type="accepted"><day>3</day><month>1</month><year>2012</year></date></history><permissions><copyright-statement>Copyright © 2012 Ali M. El-Sheikh et al.</copyright-statement><copyright-year>2012</copyright-year><license xlink:href="https://creativecommons.org/licenses/by/3.0/"><license-p>This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p><italic>Purpose.</italic> To investigate the predictability of simplifying mandibular overdenture treatment using one-stage surgery and early prosthetic loading of a single implant. <italic>Materials and Methods.</italic> Twenty edentulous patients with problematic existing mandibular dentures were treated. A single implant with a chemically modified surface (SLActive, Straumann AG, Basel, Switzerland) was placed into the mandibular midline. The patients were recalled at 3, 6 and 12 months. Clinical assessments and marginal bone loss using standardized radiographs were recorded. All complications, failures and maintenance were noted. Visual analog-scale questionnaires were used to record patient satisfaction in five categories. ANOVA was used to determine differences between means of marginal bone loss and different categories of patient staisfaction (<italic>P</italic> = 0.05). <italic>Results.</italic> The 20 early loaded implants were all surviving at the 12-month recall. All implants showed less than 1 mm of marginal bone loss by the end of the 1-year with a significant increase during the follow-up period. Few prosthetic problems were reported. Patient satisfaction was high with a significant increase in all comfort and functional parameters. <italic>Conclusions.</italic> These preliminary 1-year results indicate that early loading of a single chemically modified surface implant used to retain a mucosa-borne mandibular overdenture is a safe, reliable, and cost-effective treatment.</p></abstract></article-meta></front><body><sec id="sec1"><title>1. Introduction</title><p>Rehabilitation of the completely edentulous mandible using implants to retain a fixed prosthesis is a predictable long-term treatment modality [<xref rid="B1" ref-type="bibr">1</xref>, <xref rid="B2" ref-type="bibr">2</xref>]. High implant success rates have been achieved by Engquist et al. [<xref rid="B3" ref-type="bibr">3</xref>] (99%), Johns et al. [<xref rid="B4" ref-type="bibr">4</xref>] (96.2%), and Bergendal and Engquist [<xref rid="B5" ref-type="bibr">5</xref>] (100%), using 2 or more implants to anchor an overdenture. Two implant-retained overdentures with separated implants have been reported with high implant success rates (97–100%) and functional improvement [<xref rid="B5" ref-type="bibr">5</xref>–<xref rid="B8" ref-type="bibr">8</xref>]. There is consensus that 2 implants splinted [<xref rid="B9" ref-type="bibr">9</xref>–<xref rid="B11" ref-type="bibr">11</xref>] or unsplinted [<xref rid="B6" ref-type="bibr">6</xref>, <xref rid="B12" ref-type="bibr">12</xref>, <xref rid="B13" ref-type="bibr">13</xref>] in the interforaminal region of the mandible are sufficient to support an overdenture [<xref rid="B14" ref-type="bibr">14</xref>, <xref rid="B15" ref-type="bibr">15</xref>]. Indeed, the McGill consensus statement suggested that the 2-implant overdenture should be the first choice of treatment for the edentulous mandible [<xref rid="B16" ref-type="bibr">16</xref>]. </p><p>The success of the previous treatment modalities, while excellent, is unfortunately outside the financial scope of many compromised edentulous patients. A cost comparison study between an unsplinted 2-implant retained mandibular overdenture and a conventional complete mandibular denture showed the direct cost of the overdenture to be 2.4 times the cost of the complete denture [<xref rid="B17" ref-type="bibr">17</xref>]. It is, therefore, desirable for clinicians to be able to offer a significant functional improvement of the problematic mandibular complete denture in a cost effective manner. Concomitantly, a reduction in the overall time frame of clinical, technical, and maintenance procedures needed to achieve this goal would be advantageous [<xref rid="B18" ref-type="bibr">18</xref>]. </p><p>Further directions with case reports and prospective studies point towards a more conservative approach: the use of only a single implant to support a mandibular overdenture [<xref rid="B18" ref-type="bibr">18</xref>–<xref rid="B24" ref-type="bibr">24</xref>]. Implant outcome and patient satisfaction has shown to be comparable whether one or two implants are used for support of mandibular overdentures [<xref rid="B23" ref-type="bibr">23</xref>, <xref rid="B24" ref-type="bibr">24</xref>]. </p><p>A chemically modified titanium surface, SLActive (Straumann AG, Basel, Switzerland), has been developed, using the well-documented topography of the sandblasted, large grit, acid-etched (SLA, Straumann AG) surface. The surface is chemically active, with high surface free energy, reduced atmospheric hydrocarbon contamination, and strong hydrophilicity; the water contact angle is 0° compared with 139.9° for the standard SLA surface [<xref rid="B25" ref-type="bibr">25</xref>, <xref rid="B26" ref-type="bibr">26</xref>]. </p><p>This surface showed enhanced bone formation and significantly increased cellular activity and proliferation of vascular structures compared with the conventional SLA surface in the first 14 days following implantation, as demonstrated by histological and immunohistochemical evaluation [<xref rid="B27" ref-type="bibr">27</xref>]. In vivo animal studies have demonstrated 60% greater bone formation at the SLActive surface compared with SLA, and there is earlier formation of more mature bone [<xref rid="B28" ref-type="bibr">28</xref>]. Mean removal torque values were also found to be consistently higher in the first 8 weeks, corresponding to the early healing period [<xref rid="B29" ref-type="bibr">29</xref>]. This evidence suggests increased implant stability in the critical early osseointegrated period. Therefore, early loading protocol (3-4 weeks) using SLActive implants has become more accepted and more prevalent for situations ranging from single-tooth replacement to full-arch restorations [<xref rid="B30" ref-type="bibr">30</xref>, <xref rid="B31" ref-type="bibr">31</xref>]. </p><p>The purpose of this study was to investigate the predictability of simplifying mandibular overdenture treatment using one-stage surgery and early prosthetic loading of a single chemically modified titanium surface (SLActive) implant.</p></sec><sec id="sec2"><title>2. Materials and Methods</title><sec sec-type="subsection" id="sec2.1"><title>2.1. Patient Selection</title><p>Twenty completely edentulous subjects, 12 men and 8 women, ranging from 52 to 70 years of age (mean age 62 years) were included in the study. These patients were treated in Dammam Dental Centre, Dammam Medical Complex (Dammam, Saudi Arabia) in the period from January to April 2010. All patients signed an informed consent form. Ethical approval for the project was granted by the Human Research Ethics Committee of The Dammam Medical Complex, Dammam, Saudi Arabia. The primary complaints among the patients referred to the clinic for treatment were related to poor retention of the mandibular denture, instability, denture sores, and phonetic problems.</p><p>Inclusion criteria dictated that the patient is completely edentulous for at least 2 years, has a maladaptive mandibular denture, and has sufficient bone for an implant of at least 10 mm length and 4.1 mm diameter. Exclusion criteria included any medical condition contraindicating implant surgery, logistic or physical reasons that could affect follow-up, psychiatric problems, and disorders to the implant site related to a history of radiation therapy to the head and neck, or bone augmentation.</p></sec><sec sec-type="subsection" id="sec2.2"><title>2.2. Surgical Procedures</title><p>Thorough clinical evaluation of the proposed implant placement site was carried out. Preoperative panoramic, conventional lateral cephalometric, and periapical radiographs were used for radiographic evaluation of the placement site to avoid potential complications with important anatomy in this region. </p><p>The components used were regular platform soft tissue level implants (SLActive, Straumann AG, Basel, Switzerland) with a diameter of 4.1 mm. The Straumann 3.4 mm height retentive anchor with a titanium matrix provided the prosthetic anchorage. All patients were provided with a single implant of at least 10 mm in length inserted in the mandibular midline. Twelve patients were provided with 10 mm long implants while the remaining eight patients were provided with 12 mm long implants.</p><p>Bilateral mental nerve blocks and local infiltration in the labial and lingual sulcus were administered with lignocaine 2%. One-stage surgical approach was followed throughout the whole study (<xref ref-type="fig" rid="fig1">Figure 1</xref>). A minimal crestal incision (envelope type) was made, and a mucoperiosteal flap was raised, on both the labial and the lingual aspects, to enable adequate visualization of the lingual aspect of the mandible and to evenly divide the available keratinized tissue. This enabled the abutment to be surrounded by attached gingiva. The osteotomy was prepared using a standard bone drilling protocol, according to the manufacturer's directions with extreme care to avoid penetration of the lingual or inferior cortex. Bone quality was identified, and bone tap was used in types 1 and 2. Initial implant stability was tested manually by hand and insertion torques ≥35 Ncm were acceptable. Healing abutments of appropriate length were connected, and the mucosa was adjusted and sutured (4-0 Vicryl, Ethicon, Johnson & Johnson, Brussels, Belgium).</p><p>Any patients with implants lacking primary stability at this stage were excluded from further participation in the study and replaced; this was not considered an implant or treatment failure. Any patients with inadequate bone at the time of surgery were also excluded from further participation in the study. Patients excluded for these reasons were offered implantation using the conventional delayed loading protocol or another form of treatment. </p><p>Antibiotic (Augmentin 625 mg) and nonsteroidal anti-inflammatory (Ibuprofen 400 mg) medications were given to the patients every 8 hours for 5 days postoperatively. Immediately after surgery, the mandibular denture of each participant was modified and relined with a soft tissue conditioner (Viscogel, Dentsply, Konstanz, Germany). All patients were limited to a soft diet for 10 days and instructed to leave the denture out at night. The patients were instructed in a plaque control protocol at the time of implant placement and this was reinforced at subsequent reviews.</p></sec><sec sec-type="subsection" id="sec2.3"><title>2.3. Prosthetic Procedures</title><p>Three weeks after implant placement, the healing abutment was removed and the retentive anchor was screwed to the implant (<xref ref-type="fig" rid="fig2">Figure 2</xref>). A torque of 35 Ncm was used for tightening the retentive anchor. Preliminary impressions for upper and lower arches were taken with stock trays using irreversible hydrocolloid (Hydrogum, Zhermack, Italy). The impression for the lower arch was taken directly over the retentive anchor. Secondary impressions were taken with autopolymerized acrylic resin special trays using vinyl polysiloxane impression material (Express, 3 M ESPE Dental Products, USA). The transfer pin was positioned in the lower impression before pouring it (<xref ref-type="fig" rid="fig3">Figure 3</xref>). Record blocks were fabricated on the duplicates of the master models for jaw registration. Teeth try-in and manufacturing of the acrylic dentures were carried out using standard prosthetic procedures. The titanium matrix (<xref ref-type="fig" rid="fig4">Figure 4</xref>) was incorporated in the final prosthesis using the direct technique inside the patient's mouth. Fabrication of the prostheses was finished in 1 week. Therefore, the maxillary complete denture and implant-retained mandibular overdenture (<xref ref-type="fig" rid="fig5">Figure 5</xref>) were delivered to the participants approximately 4 weeks after implant placement.</p></sec><sec sec-type="subsection" id="sec2.4"><title>2.4. Radiographic Analysis</title><p>Standardized intraoral radiographs using a long cone technique of the implant were obtained. To provide a geometrically reproducible alignment, an index was recorded for each patient on the inserted mandibular overdenture with the use of vinyl siloxane material. With the aid of Hawe's sensor holder system (Kerr, KerrHawe SA, Switzerland), the radiographs were taken using direct digital imaging system (Trophy RVG, William Green Pty Ltd., Australia). Images were displayed on a computer screen with such a dimension and brightness that the observer could read comfortable and accurately the image. On each image, the implant-retentive anchor interface and first bone-to-implant contact were identified and marked with a cursor on the mesial and distal sides of the implant. The analysis program calculated and reported the distance between the two points with a degree of accuracy of ±0.01 mm. The same procedure was performed with all follow-up radiographs. The initial postoperative radiographs immediately after insertion of the new/final overdentures (baseline radiography) were compared with the follow-up radiographs 3, 6, and 12 months of functional loading. The vertical bone loss was calculated by subtracting the bone heights in the baseline radiographs from those of follow-up radiographs. Data were collected blindly by one experienced observer throughout the entire study.</p></sec><sec sec-type="subsection" id="sec2.5"><title>2.5. Patient Satisfaction</title><p>Self-administered questionnaires that followed the Visual Analogue Scale (VAS) method were completed by patients preoperatively and at each scheduled recall to assess oral comfort and function [<xref rid="B32" ref-type="bibr">32</xref>]. Each VAS questionnaire consisted of a 100 mm line anchored at the beginning and end by opposing responses/statements such as “not at all satisfied” to “totally satisfied”. The participants marked a vertical line on the horizontal VAS line to indicate their feeling. Scores were determined by measuring the distance (in mm) from the left starting point of the line to the intersection of the response line. There were 10 questions, in 5 categories: general satisfaction (not at all satisfied, totally satisfied), social life (not at all improved the social life, totally improved the social life), mastication of hard food (not at all improved mastication of hard food, totally improved mastication of hard food), comfort (not at all comfort, totally comfort), and fit (not at all fit, totally fit).</p></sec><sec sec-type="subsection" id="sec2.6"><title>2.6. Data Collection</title><p>The data collection (clinical and radiographic outcomes) of all patients was performed as follows: at the completion of the prosthetic treatment (baseline) and after 3, 6, and 12 months of functional loading.</p></sec><sec sec-type="subsection" id="sec2.7"><title>2.7. Statistical Analysis</title><p>The measurements for the marginal bone loss were carried out on the mesial and distal surface for each implant and the mean was taken. The difference between the values at the baseline and the follow-up recall visits was based on the average bone loss value for each implant. The data were statistically analyzed using one-way repeated measures ANOVA followed by Tukey's test at 95% confidence level (SPSS for Windows, version 10.0, SPSS Incorporated, Chicago, IL, USA).</p></sec></sec><sec id="sec3"><title>3. Results</title><p>Three patients were excluded from the study during the surgical placement of the implants. Two patients were excluded due to lack of primary stability and one due to inadequate bone. The 20 early loaded implants were all surviving at the 12-month recall. Prosthetic problems were relatively few with attachment functioning well at the 1-year recall and reline unnecessary. Two patients required the spring of the titanium matrix to be replaced with a new one due to loss of the retention approximately 9 months after functional loading. Plaque control was considered acceptable for most patients and considered relatively simple by the patients themselves. Calculus formation that impeded seating of the titanium matrix was encountered on 2 occasions and was further prevented by more diligent hygiene. Soft tissue health was visually assessed and was acceptable in all patients with no evidence of mucosal enlargement at recall appointments, as shown in <xref ref-type="fig" rid="fig6">Figure 6</xref> (12-month follow-up).</p><p>All implants showed less than 1 mm of marginal bone loss by the end of the 1-year follow-up period. The mean vertical bone loss from baseline to 3 months was 0.30 mm (SD = 0.06). The mean vertical bone loss from baseline to 6 months was 0.63 mm (SD = 0.07). The mean vertical bone loss from baseline to 12 months was 0.93 mm (SD = 0.06). The comparison of the mean values of bone loss from 3 to 6 months, from 3 to 12 months, and from 6 to 12 months was statistically significant (<italic>P</italic> < 0.001).</p><p>The mean values and standard deviations (in mm) of comfort and functional parameters in the VAS questionnaires filled by all patients at pretreatment and all recall appointments were summarized in <xref ref-type="table" rid="tab1">Table 1</xref>. Statistical analysis of these data showed a significant improvement in all parameters of oral comfort and prosthesis function (<italic>P</italic> < 0.001). Direct questioning indicated that common pretreatment problems, such as recurrent denture ulceration, had been eliminated and nonmasticatory functions such as yawning and laughing could be accomplished without complications.</p></sec><sec id="sec4"><title>4. Discussion</title><p>The conventional loading protocols for dental implants allow for a period of undisturbed healing after implant placement, to minimize the risk of healing and osseointegration complications. In recent years, shorter restoration times have become more common, especially due to increasing patient demands.</p><p>The purpose of this prospective study was to ascertain whether simplifying mandibular overdenture treatment using one-stage surgery and early prosthetic loading of a single implant would achieve acceptable implant success rates and provide the functional improvement expected using conventional techniques. While the study may be of limited duration, it provides sound support for the hypothesis that the single-implant mandibular overdenture can provide improved retention, stability, masticatory performance, and confidence for the maladaptive complete denture wearers. The limitations of the small sample size of 20 participants and the short follow-up period of 1 year need to be acknowledged, and the findings presented, therefore, must be interpreted cautiously.</p><p>Presurgical evaluation of the patient was simplified by using the relatively inexpensive panoramic, lateral cephalometric, and periapical radiographs. These important diagnostic aids, together with adequate visualization of the lingual surface of the bony ridge after flap evaluation, cannot be overstated in light of reports of life-threatening hemorrhage from the floor of the mouth during routine implant placement in this region [<xref rid="B33" ref-type="bibr">33</xref>, <xref rid="B34" ref-type="bibr">34</xref>]. The present study on the early functioning single-implant overdenture showed excellent survival rates (100%) and dramatically improved patient-reported satisfaction levels in patients with pretreatment denture problems. These results are in agreement with the study by Alsabeeha et al. [<xref rid="B30" ref-type="bibr">30</xref>] which reported 100% of early loading for the Southern wide and Neoss regular implants. With respects to the 100% survival reported, the possibility that the authors are skilled clinicians experienced with this technique should be considered, so the single-implant procedure cannot be generalized to the entire practicing community. However, the procedures involved are not complex, provided that the mentioned protocol is followed. It is difficult to postulate whether two implants are twice as effective as one or even whether there is any discernable difference from a patient perspective.</p><p>In general, implant overdentures have a less controlled loading when compared to fixed prostheses [<xref rid="B35" ref-type="bibr">35</xref>]. It may be postulated that forces, both axial and lateral, generated by an overdenture on a single implant have the potential to be greater than those produced by a multiple implant-retained overdenture. Maeda et al. [<xref rid="B36" ref-type="bibr">36</xref>] examined the biomechanical rationale of a single implant-retained mandibular overdenture using an in vitro model. The model revealed statistically significantly smaller lateral forces to the ball abutments for single-compared to two-implant overdentures with molar loading. A higher load was observed when the denture was loaded in the midline region. No significant difference in three-dimensional denture base movement was observed between single- and two-implant overdentures in the midline and molar regions. They concluded that, overall, the single-implant overdenture had similar biomechanical effects to a two-implant overdenture in terms of lateral forces to the abutment and denture base movements under molar functional loads. However, the authors did stress the in vitro nature of the model and the need for follow-up studies performed in a clinical setting.</p><p>Prosthetic problems were relatively few compared to other studies [<xref rid="B14" ref-type="bibr">14</xref>, <xref rid="B15" ref-type="bibr">15</xref>], with attachment functioning well at the 1-year recall and relines unnecessary. This is in agreement with the study by Liddelow and Henry [<xref rid="B18" ref-type="bibr">18</xref>] in which plastic caps and rubber O-rings were used. The present study used the titanium matrix with the spring. The inherent resilience with these kinds of attachments (i.e., plastic caps and rubber O-rings, and titanium matrix and spring) may allow more movement and, therefore, less strain and potential for wear. The other studies [<xref rid="B14" ref-type="bibr">14</xref>, <xref rid="B15" ref-type="bibr">15</xref>] used metal retentive caps which may explain the occurrence of more prosthetic problems in these studies. The titanium matrix is, however, substantially small, resulting in an enough amount of denture base around the attachment. Therefore, no fracture of the denture bases at the attachment site was recorded in all cases. A denture with this type of attachment is primarily tissue borne and implant retained. From a prosthodontic perspective, if the implant is not placed in the ideal position, an unfavorable overbulking of the denture base would result.</p><p>Plaque control was considered acceptable for most patients and considered relatively simple by the patients themselves. Soft tissue health was acceptable in all patients with no evidence of mucosal enlargement at all recall appointments. The findings in the present study are in agreement with the studies of Liddelow and Henry [<xref rid="B18" ref-type="bibr">18</xref>] and Cordioli et al. [<xref rid="B19" ref-type="bibr">19</xref>], which also reported no mucosal enlargement during the follow-up period. Mucosal enlargement has been reported in other studies such as that by Engquist et al. [<xref rid="B3" ref-type="bibr">3</xref>], which had an incidence of 25%, and that by Wright et al. [<xref rid="B11" ref-type="bibr">11</xref>], which reported 35%.</p><p>The overall mean marginal bone loss after 1 year of function in the present study was less than 1 mm which is in agreement with previous studies [<xref rid="B18" ref-type="bibr">18</xref>–<xref rid="B21" ref-type="bibr">21</xref>]. The comparison of the mean values of bone loss from 3 to 6 months, from 3 to 12 months, and from 6 to 12 months was statistically significant. The explanation for that could be the presence of only one implant in the mandible which might have been subjected to excessive forces.</p><p>The cost of treatment for edentulous patients is a significant determinant of treatment acceptance, compared to other groups of patients. Any reduction in cost to the patient becomes more critical. The study measuring the cost of implant overdenture therapy has been done with a microcosting technique, which examines the direct cost to the patient and, also, indirect costs, such as time and transportation [<xref rid="B17" ref-type="bibr">17</xref>]. Measured in this way, the difference in cost between 1 and 2 implants would be primarily half the component costs, as the time differential from both the surgical and prosthodontics viewpoint would be minimal. The few prosthetic problems reported during the 1-year follow-up period are interesting from a maintenance cost standpoint. If this type of overdenture design and attachment component has a lower maintenance requirement, then this has favorable implications with respect to cost-effectiveness.</p><p>The preliminary 1-year report on this procedure indicates that it is a positive treatment modality, which could make it possible for completely edentulous patients with limited resources to benefit from an implant-retained prosthesis. It may well be considered to be the entry level treatment option for rehabilitation of the edentulous mandible in selected patients, especially the underprivileged geriatric groups. A limitation of this study is the lack of a comparison group with the more conventional 2-implant overdenture. Given the clear improvements and reduced costs with this modality, serious consideration for longer term and more extensive clinical trials is warranted. In long term, with favorable results, the McGill consensus statement may be challenged.</p></sec><sec id="sec5"><title>5. Conclusions</title><p>Within the limitation of this study and the preliminary nature of this 1-year report, it may be concluded that the early loaded, single implant-retained mandibular overdenture, using a chemically modified surface implant (SLActive), is an alternative treatment proposition for selected patients. The relatively simple treatment protocol and reduced component and laboratory involvement mean that a greater number of edentulous patients could benefit from this protocol. 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