Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Surgical management of oral submucous fibrosis in an edentulous patient: A procedural challenge</title><author><name sortKey="Mahajan, Amit D" sort="Mahajan, Amit D" uniqKey="Mahajan A" first="Amit D." last="Mahajan">Amit D. Mahajan</name><affiliation><nlm:aff id="aff1">Department of Oral and Maxillofacial Surgery, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Piparia, Vadodara, Gujarat</nlm:aff></affiliation></author><author><name sortKey="Tatu, Rohit J" sort="Tatu, Rohit J" uniqKey="Tatu R" first="Rohit J." last="Tatu">Rohit J. Tatu</name><affiliation><nlm:aff id="aff1">Department of Oral and Maxillofacial Surgery, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Piparia, Vadodara, Gujarat</nlm:aff></affiliation></author><author><name sortKey="Shenoy, Nithin A" sort="Shenoy, Nithin A" uniqKey="Shenoy N" first="Nithin A." last="Shenoy">Nithin A. Shenoy</name><affiliation><nlm:aff id="aff1">Department of Oral and Maxillofacial Surgery, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Piparia, Vadodara, Gujarat</nlm:aff></affiliation></author><author><name sortKey="Sharma, Vaibhav S" sort="Sharma, Vaibhav S" uniqKey="Sharma V" first="Vaibhav S." last="Sharma">Vaibhav S. Sharma</name><affiliation><nlm:aff id="aff1">Department of Oral and Maxillofacial Surgery, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Piparia, Vadodara, Gujarat</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22442590</idno><idno type="pmc">3304202</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304202</idno><idno type="RBID">PMC:3304202</idno><idno type="doi">10.4103/0975-5950.79221</idno><date when="2010">2010</date><idno type="wicri:Area/Pmc/Corpus">001F50</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001F50</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Surgical management of oral submucous fibrosis in an edentulous patient: A procedural challenge</title><author><name sortKey="Mahajan, Amit D" sort="Mahajan, Amit D" uniqKey="Mahajan A" first="Amit D." last="Mahajan">Amit D. Mahajan</name><affiliation><nlm:aff id="aff1">Department of Oral and Maxillofacial Surgery, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Piparia, Vadodara, Gujarat</nlm:aff></affiliation></author><author><name sortKey="Tatu, Rohit J" sort="Tatu, Rohit J" uniqKey="Tatu R" first="Rohit J." last="Tatu">Rohit J. Tatu</name><affiliation><nlm:aff id="aff1">Department of Oral and Maxillofacial Surgery, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Piparia, Vadodara, Gujarat</nlm:aff></affiliation></author><author><name sortKey="Shenoy, Nithin A" sort="Shenoy, Nithin A" uniqKey="Shenoy N" first="Nithin A." last="Shenoy">Nithin A. Shenoy</name><affiliation><nlm:aff id="aff1">Department of Oral and Maxillofacial Surgery, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Piparia, Vadodara, Gujarat</nlm:aff></affiliation></author><author><name sortKey="Sharma, Vaibhav S" sort="Sharma, Vaibhav S" uniqKey="Sharma V" first="Vaibhav S." last="Sharma">Vaibhav S. Sharma</name><affiliation><nlm:aff id="aff1">Department of Oral and Maxillofacial Surgery, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Piparia, Vadodara, Gujarat</nlm:aff></affiliation></author></analytic><series><title level="j">National Journal of Maxillofacial Surgery</title><idno type="ISSN">0975-5950</idno><idno type="eISSN">2229-3418</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Prosthetic rehabilitation of patients with oral submucous fibrosis (OSMF) offers a formidable challenge due to restricted mouth opening. Physiotherapy via interocclusal force application is the mainstay for surgical treatment. Herein, we report a case of a man with OSMF requiring construction of dentures. The main objective was to deliver intra-operative and post operative inter occlusal forces without fracturing the mandible and thus providing rehabilitation to the patient prosthetically. An edentulous male patient reported with grade IVA OSMF to our department to improve his mouth opening for denture construction. The patient was managed successfully using surgical sectioning of the fibrous bands. Inter occlusal force application for mouth opening during the operation and post operative physiotherapy were facilitated using custom-made occlusal splints. Satisfactory mouth opening was achieved, with good healing and no event of infection or fracture. Here, we propose an easy method to achieve adequate mouth opening in an edentulous patient of OSMF, with atrophic ridges; without the chances of fracture of either jaw.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Cox, Sc" uniqKey="Cox S">SC Cox</name></author><author><name sortKey="Walker, Dm" uniqKey="Walker D">DM Walker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aziz, Sr" uniqKey="Aziz S">SR Aziz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paissat, Dk" uniqKey="Paissat D">DK Paissat</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khanna, Jn" uniqKey="Khanna J">JN Khanna</name></author><author><name sortKey="Andrade, Nn" uniqKey="Andrade N">NN Andrade</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hao, Sp" uniqKey="Hao S">SP Hao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rajendran, R" uniqKey="Rajendran R">R Rajendran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yeh, Cj" uniqKey="Yeh C">CJ Yeh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Singh, M" uniqKey="Singh M">M Singh</name></author><author><name sortKey="Niranjan, Hs" uniqKey="Niranjan H">HS Niranjan</name></author><author><name sortKey="Mehrotra, R" uniqKey="Mehrotra R">R Mehrotra</name></author><author><name sortKey="Sharma, D" uniqKey="Sharma D">D Sharma</name></author><author><name sortKey="Gupta, Sc" uniqKey="Gupta S">SC Gupta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rai, B" uniqKey="Rai B">B Rai</name></author><author><name sortKey="Kaur, J" uniqKey="Kaur J">J Kaur</name></author><author><name sortKey="Jacobs, R" uniqKey="Jacobs R">R Jacobs</name></author><author><name sortKey="Singh, J" uniqKey="Singh J">J Singh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Granizo, Rm" uniqKey="Granizo R">RM Granizo</name></author><author><name sortKey="Naval, L" uniqKey="Naval L">L Naval</name></author><author><name sortKey="Costas, A" uniqKey="Costas A">A Costas</name></author><author><name sortKey="Goizueta, C" uniqKey="Goizueta C">C Goizueta</name></author><author><name sortKey="Rodriguez, F" uniqKey="Rodriguez F">F Rodriguez</name></author><author><name sortKey="Monje, F" uniqKey="Monje F">F Monje</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stuzin, Jm" uniqKey="Stuzin J">JM Stuzin</name></author><author><name sortKey="Wagstrom, L" uniqKey="Wagstrom L">L Wagstrom</name></author><author><name sortKey="Kawamoto, Hk" uniqKey="Kawamoto H">HK Kawamoto</name></author><author><name sortKey="Wolfe, Sa" uniqKey="Wolfe S">SA Wolfe</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="case-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Natl J Maxillofac Surg</journal-id><journal-id journal-id-type="publisher-id">NJMS</journal-id><journal-title-group><journal-title>National Journal of Maxillofacial Surgery</journal-title></journal-title-group><issn pub-type="ppub">0975-5950</issn><issn pub-type="epub">2229-3418</issn><publisher><publisher-name>Medknow Publications</publisher-name><publisher-loc>India</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">22442590</article-id><article-id pub-id-type="pmc">3304202</article-id><article-id pub-id-type="publisher-id">NJMS-1-161</article-id><article-id pub-id-type="doi">10.4103/0975-5950.79221</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Surgical management of oral submucous fibrosis in an edentulous patient: A procedural challenge</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Mahajan</surname><given-names>Amit D.</given-names></name><xref ref-type="aff" rid="aff1"></xref><xref ref-type="corresp" rid="cor1"></xref></contrib><contrib contrib-type="author"><name><surname>Tatu</surname><given-names>Rohit J.</given-names></name><xref ref-type="aff" rid="aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Shenoy</surname><given-names>Nithin A.</given-names></name><xref ref-type="aff" rid="aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Sharma</surname><given-names>Vaibhav S.</given-names></name><xref ref-type="aff" rid="aff1"></xref></contrib></contrib-group><aff id="aff1">Department of Oral and Maxillofacial Surgery, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Piparia, Vadodara, Gujarat</aff><author-notes><corresp id="cor1"><bold>Address for correspondence:</bold> Dr. Amit D Mahajan, Department of Oral and Maxillofacial Surgery, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Waghodia Road, Piparia-391760, Vadodara, Gujarat E mail: <email xlink:href="dramitmahajan@indiatimes.com">dramitmahajan@indiatimes.com</email></corresp></author-notes><pub-date pub-type="ppub"><season>Jul-Dec</season><year>2010</year></pub-date><volume>1</volume><issue>2</issue><fpage>161</fpage><lpage>163</lpage><permissions><copyright-statement>© National Journal of Maxillofacial Surgery</copyright-statement><copyright-year>2010</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p>Prosthetic rehabilitation of patients with oral submucous fibrosis (OSMF) offers a formidable challenge due to restricted mouth opening. Physiotherapy via interocclusal force application is the mainstay for surgical treatment. Herein, we report a case of a man with OSMF requiring construction of dentures. The main objective was to deliver intra-operative and post operative inter occlusal forces without fracturing the mandible and thus providing rehabilitation to the patient prosthetically. An edentulous male patient reported with grade IVA OSMF to our department to improve his mouth opening for denture construction. The patient was managed successfully using surgical sectioning of the fibrous bands. Inter occlusal force application for mouth opening during the operation and post operative physiotherapy were facilitated using custom-made occlusal splints. Satisfactory mouth opening was achieved, with good healing and no event of infection or fracture. Here, we propose an easy method to achieve adequate mouth opening in an edentulous patient of OSMF, with atrophic ridges; without the chances of fracture of either jaw.</p></abstract><kwd-group><kwd>Edentulous patient</kwd><kwd>fibrous bands</kwd><kwd>inter–occlusal force</kwd><kwd>mouth opening</kwd><kwd>occlusal splints</kwd><kwd>oral submucous fibrosis</kwd></kwd-group></article-meta></front><body><sec id="sec1-1"><title>I<sc>NTRODUCTION</sc></title><p>Oral submucous fibrosis (OSMF) is a chronic, debilitating disease, characterized by inflammation and progressive fibrosis of the submucosal tissues. It results in marked rigidity and an eventual inability to open the mouth.[<xref ref-type="bibr" rid="ref1">1</xref><xref ref-type="bibr" rid="ref2">2</xref>] The buccal mucosa is the most commonly involved site, but any part of the oral cavity can be involved, including the pharynx.[<xref ref-type="bibr" rid="ref3">3</xref>]</p><p>Good mouth opening is a pre requisite for prosthetic rehabilitation in any patient. Because of the varying degrees of restriction in mouth opening, edentulous patients with OSMF present a formidable challenge to treatment. Application of inter-occlusal forces to achieve adequate mouth opening forms an integral part of treatment of OSMF. Patients with good dentition are amenable to application of such forces but in edentulous patients the forces will directly get transmitted to the atrophic ridges rendering them vulnerable to fracture and soft tissue injury. Post operative physiotherapy will also be hampered in such patients.</p></sec><sec id="sec1-2"><title>C<sc>ASE</sc> R<sc>EPORT</sc></title><p>A 61 year old, completely edentulous male patient reported to the Oral and Maxillofacial Surgery Department of K.M. Shah Dental College and Hospital, Piparia, India, with a complaint of inability to get dentures constructed due to reduced mouth opening. The patient had history of paan masala (mixture of areca, slaked lime and tobacco) chewing for about 10 years duration. He had noticed a gradual decrease in mouth opening since the last 3—4 years. He reported to have discontinued the habit due to severe burning sensation of the oral mucosa and inability to eat hot and spicy food, since the past 2 years. There was no significant medical history. The patient was diagnosed as having Grade IVA OSMF according to Khanna <italic>et al</italic>.[<xref ref-type="bibr" rid="ref4">4</xref>]</p><p>Impressions of both arches were made with customized plastic perforated trays. Study casts were then made and occlusal splints were constructed by the heat cure method so that the splints had adequate strength while delivering the inter-occlusal forces. The splints were made such that they had an occlusal table on which the working ends of the mouth gag could be placed. Grooves were made on the splints to facilitate fixation of the splints with wires. Additional holes were drilled in the occlusal table to accommodate the free ends of the twisted wires.</p><p>The surgery was performed under general anesthesia with nasal intubation. The standard incision was made with a surgical knife. Standard dissection was performed with the help of an artery and finger dissection.</p><p>The maxillary occlusal splint was placed and secured with per alveolar wiring followed by fixation of the mandibular occlusal splint with circum mandibular wiring. The mouth was then forced open with a mouth gag to achieve a splint to splint distance of 35 mm [<xref ref-type="fig" rid="F1">Figure 1</xref>]. This was considered to be adequate mouth opening for future prosthetic rehabilitation. Bilateral buccal defects of 3.5 cm × 2.0 cm were covered by BFP grafts using the standard technique[<xref ref-type="bibr" rid="ref5">5</xref>] [<xref ref-type="fig" rid="F2">Figure 2</xref>].</p><fig id="F1" position="float"><label>Figure 1</label><caption><p>Intra-operative photograph showing application of inter-occlusal force with the occlusal splints in place</p></caption><graphic xlink:href="NJMS-1-161-g001"></graphic></fig><fig id="F2" position="float"><label>Figure 2</label><caption><p>Intraoperative photograph showing the buccal fat pad</p></caption><graphic xlink:href="NJMS-1-161-g002"></graphic></fig><p>The patient was hospitalized for 15 days post-operatively. Ryle's tube feeding was instituted for 1 week post-operatively to maintain oral-hygiene while the grafted buccal fat pad was being epithelized. The post-operative mouth-opening exercise was started as soon as the patient was hemo-dynamically stabilized [<xref ref-type="fig" rid="F3">Figure 3</xref>]. A mouth opening of 30 mm was maintained. By the second post-operative week the patient was trained and motivated to perform mouth opening exercises with the help of the Heister's mouth gag. Parentral medications were given for 7 days post-operatively followed by oral medications for 5 days. Daily intra-oral irrigation was performed with normal saline. The occlusal splints were removed after 4 weeks of surgery. Mouth opening after 4 weeks is shown in <xref ref-type="fig" rid="F4">Figure 4</xref>. After that, the patient was referred for construction of complete dentures.</p><fig id="F3" position="float"><label>Figure 3</label><caption><p>Application of brisement force post operative</p></caption><graphic xlink:href="NJMS-1-161-g003"></graphic></fig><fig id="F4" position="float"><label>Figure 4</label><caption><p>Photograph showing improved mouth opening 4 weeks post operatively.</p></caption><graphic xlink:href="NJMS-1-161-g004"></graphic></fig></sec><sec id="sec1-3"><title>D<sc>ISCUSSION</sc></title><p>Oral submucosal fibrosis is a well known clinical entity since the time of Sushruta when it was called “vidari”. Joshi, in1953, was the first person to describe this entity in India.[<xref ref-type="bibr" rid="ref6">6</xref>] Although the exact etiology is not known, chronic irritation due to the habit of chewing betel nut in various forms is a major contributory factor. The onset of the condition is insidious and the most common initial symptom is a burning sensation experienced on eating spicy, hot food or on the intake of hot beverages. Early symptoms are blisters, ulcerations, or recurrent stomatitis. Restricted tongue movements are seen in advanced cases.[<xref ref-type="bibr" rid="ref7">7</xref>]</p><p>Various treatment modalities have been suggested and are being practiced including both medicinal and surgical modalities. Medicinal agents like hydrocortisone, hyaluronidase, triamcinalone and a combination thereof have also been used, but without significant results.[<xref ref-type="bibr" rid="ref8">8</xref>] Extensive research over half of the past century has suggested use of curcumin in precancerous conditions due its anti-inflammatory, anti-oxidant and proapoptotic activities.[<xref ref-type="bibr" rid="ref9">9</xref>]</p><p>Surgical treatment includes excision of fibrous bands and reconstruction of the resultant defects using skin grafts and local, regional and distant flaps such as oral mucosal flaps, myomucosal island flaps, tongue flaps, local muscular flaps like temporalis or temporalis fasia transfer and buccal fat pad.[<xref ref-type="bibr" rid="ref10">10</xref>] Temporalis myotomy with coronoidectomy has also been advocated.[<xref ref-type="bibr" rid="ref4">4</xref>]</p><p>It is very difficult to apply inter occlusal forces in severely resorbed, atrophic, edentulous ridges as there is an ever-imminent risk of fracture of the jaws. Soft tissue injury can also occur due to placement of the blades of the gag on them.[<xref ref-type="bibr" rid="ref11">11</xref>]</p><p>A worldwide web search of databases with the key words OSMF and edentulous patient resulted in no research articles published on surgical management in edentulous patients till date.</p><p>Use of occlusal splints and gunning splints is widespread in the management of maxillofacial trauma in edentulous patients. As in the present case occlusal splints can be successfully used to gain adequate mouth opening by delivering satisfactory inter occlusal forces. This technique can also be useful in patients with severely compromised periodontal status where the teeth might not be able to withstand the forces of physiotherapy. Apart from these situations, partially dentulous patients also are potential candidates for this technique. Patients who have existing dentures can have them wired to the jaws to be used as splints.</p></sec><sec id="sec1-4"><title>C<sc>ONCLUSION</sc></title><p>Here, we propose an easy method to achieve normal mouth opening in an edentulous patient of OSMF. The technique is fairly simple which eliminates the chances of fracture of either jaw, while providing the scope for post-operative physiotherapy, which is the mainstay for maintaining surgically achieved mouth opening.</p></sec></body><back><ack><title>A<sc>CKNOWLEDGMENT</sc></title><p>The authors are thankful to the institute for providing the infrastructure to plan this surgery and especially Dr. Manjunatha BS, Department of Oral Pathology, during the prepartion of this manuscript.</p></ack><fn-group><fn fn-type="supported-by"><p><bold>Source of Support:</bold> Nil.</p></fn><fn fn-type="conflict"><p><bold>Conflict of Interest:</bold> None declared.</p></fn></fn-group><ref-list><title>R<sc>EFERENCES</sc></title><ref id="ref1"><label>1</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Cox</surname><given-names>SC</given-names></name><name><surname>Walker</surname><given-names>DM</given-names></name></person-group><article-title>Oral submucous fibrosis.A review</article-title><source>Aust Dent J</source><year>1996</year><volume>41</volume><fpage>294</fpage><lpage>9</lpage><pub-id pub-id-type="pmid">8961601</pub-id></element-citation></ref><ref id="ref2"><label>2</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Aziz</surname><given-names>SR</given-names></name></person-group><article-title>Oral submucous fibrosis: an unusual disease</article-title><source>J N J Dent Assoc</source><year>1997</year><volume>68</volume><fpage>17</fpage><lpage>9</lpage><pub-id pub-id-type="pmid">9540735</pub-id></element-citation></ref><ref id="ref3"><label>3</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Paissat</surname><given-names>DK</given-names></name></person-group><article-title>Oral submucous fibrosis</article-title><source>Int J Oral Surg</source><year>1981</year><volume>10</volume><fpage>307</fpage><lpage>12</lpage><pub-id pub-id-type="pmid">6807916</pub-id></element-citation></ref><ref id="ref4"><label>4</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Khanna</surname><given-names>JN</given-names></name><name><surname>Andrade</surname><given-names>NN</given-names></name></person-group><article-title>Oral submucous fibrosis: a new concept in surgical management. Report of 100 cases</article-title><source>Int J Oral Maxillofac Surg</source><year>1995</year><volume>24</volume><fpage>433</fpage><lpage>9</lpage><pub-id pub-id-type="pmid">8636640</pub-id></element-citation></ref><ref id="ref5"><label>5</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hao</surname><given-names>SP</given-names></name></person-group><article-title>Reconstruction of oral defects with the pedicled buccal fat pad flap</article-title><source>Otolaryngol Head Neck Surg</source><year>2000</year><volume>122</volume><fpage>863</fpage><lpage>7</lpage><pub-id pub-id-type="pmid">10828800</pub-id></element-citation></ref><ref id="ref6"><label>6</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rajendran</surname><given-names>R</given-names></name></person-group><article-title>Oral submucous fibrosis: etiology, pathogenesis and future research</article-title><source>Bull World Health Organ</source><year>1994</year><volume>72</volume><fpage>985</fpage><lpage>96</lpage><pub-id pub-id-type="pmid">7867145</pub-id></element-citation></ref><ref id="ref7"><label>7</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Yeh</surname><given-names>CJ</given-names></name></person-group><article-title>Application of the buccal fat pad to the surgical treatment of oral submucous fibrosis</article-title><source>Int J Oral Maxillofac Surg</source><year>1996</year><volume>25</volume><fpage>130</fpage><lpage>3</lpage><pub-id pub-id-type="pmid">8727586</pub-id></element-citation></ref><ref id="ref8"><label>8</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Singh</surname><given-names>M</given-names></name><name><surname>Niranjan</surname><given-names>HS</given-names></name><name><surname>Mehrotra</surname><given-names>R</given-names></name><name><surname>Sharma</surname><given-names>D</given-names></name><name><surname>Gupta</surname><given-names>SC</given-names></name></person-group><article-title>Efficacy of hydrocortisone acetate/hyaluronidase vs triamcinolone acetonide/hyaluronidase in the treatment of oral submucous fibrosis</article-title><source>Indian J Med Res</source><year>2010</year><volume>131</volume><fpage>665</fpage><lpage>9</lpage><pub-id pub-id-type="pmid">20516538</pub-id></element-citation></ref><ref id="ref9"><label>9</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rai</surname><given-names>B</given-names></name><name><surname>Kaur</surname><given-names>J</given-names></name><name><surname>Jacobs</surname><given-names>R</given-names></name><name><surname>Singh</surname><given-names>J</given-names></name></person-group><article-title>Possible action mechanism for curcumin in pre-cancerous lesions based on serum and salivary markers of oxidative stress</article-title><source>J Oral Sci</source><year>2010</year><volume>52</volume><fpage>251</fpage><lpage>6</lpage><pub-id pub-id-type="pmid">20587949</pub-id></element-citation></ref><ref id="ref10"><label>10</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Granizo</surname><given-names>RM</given-names></name><name><surname>Naval</surname><given-names>L</given-names></name><name><surname>Costas</surname><given-names>A</given-names></name><name><surname>Goizueta</surname><given-names>C</given-names></name><name><surname>Rodriguez</surname><given-names>F</given-names></name><name><surname>Monje</surname><given-names>F</given-names></name></person-group><article-title>Use of buccal fat pad to repair intraoral defects-review of 30 cases</article-title><source>B J Oral Maxillofac Surg</source><year>1997</year><volume>35</volume><fpage>81</fpage><lpage>4</lpage></element-citation></ref><ref id="ref11"><label>11</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Stuzin</surname><given-names>JM</given-names></name><name><surname>Wagstrom</surname><given-names>L</given-names></name><name><surname>Kawamoto</surname><given-names>HK</given-names></name><name><surname>Wolfe</surname><given-names>SA</given-names></name></person-group><article-title>Anatomy of the frontal branch of the facial nerve: the significance of the temporal fat pad</article-title><source>Plast Reconstr Surg</source><year>1989</year><volume>83</volume><fpage>265</fpage><lpage>71</lpage><pub-id pub-id-type="pmid">2911626</pub-id></element-citation></ref></ref-list></back></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001F50 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 001F50 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.32. |  |