Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Squamous odontogenic tumor: A case report and review of literature</title><author><name sortKey="Badni, Manjunath" sort="Badni, Manjunath" uniqKey="Badni M" first="Manjunath" last="Badni">Manjunath Badni</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Nagaraja, A" sort="Nagaraja, A" uniqKey="Nagaraja A" first="A" last="Nagaraja">A. Nagaraja</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Kamath, Vv" sort="Kamath, Vv" uniqKey="Kamath V" first="Vv" last="Kamath">Vv Kamath</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22438650</idno><idno type="pmc">3303503</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303503</idno><idno type="RBID">PMC:3303503</idno><idno type="doi">10.4103/0973-029X.92986</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">001E88</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001E88</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Squamous odontogenic tumor: A case report and review of literature</title><author><name sortKey="Badni, Manjunath" sort="Badni, Manjunath" uniqKey="Badni M" first="Manjunath" last="Badni">Manjunath Badni</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Nagaraja, A" sort="Nagaraja, A" uniqKey="Nagaraja A" first="A" last="Nagaraja">A. Nagaraja</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Kamath, Vv" sort="Kamath, Vv" uniqKey="Kamath V" first="Vv" last="Kamath">Vv Kamath</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author></analytic><series><title level="j">Journal of Oral and Maxillofacial Pathology : JOMFP</title><idno type="ISSN">0973-029X</idno><idno type="eISSN">1998-393X</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The squamous odontogenic tumor (SOT) is a rare, benign, locally infiltrative neoplasm of the jaws that appears to originate from the rests of Malassez, gingival surface epithelium or from remnants of the dental lamina. SOT was first described by Pullon <italic>et al</italic>. (1975). Since then there has been paucity in the number of reported cases, especially in the Indian subcontinent. The tumor is often asymptomatic, although it can present with symptoms of pain and tooth mobility. The characteristic radiographic appearance is that of a triangular-shaped unilocular radiolucency associated with the roots of erupted, vital teeth and has a predilection for the anterior maxilla and the posterior mandible. Histologically, the tumor is characterized by the formation of variably sized nests and cords of uniform, benign-appearing, squamous epithelium with occasional vacuolization and keratinization. We report a case of SOT occurring in a 58-year-old male in the anterior mandible with unusual localization and appearance.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Rajendran, R" uniqKey="Rajendran R">R Rajendran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Philipsen, Hp" uniqKey="Philipsen H">HP Philipsen</name></author><author><name sortKey="Reichart, Pa" uniqKey="Reichart P">PA Reichart</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pullon, Pa" uniqKey="Pullon P">PA Pullon</name></author><author><name sortKey="Shafer, Wg" uniqKey="Shafer W">WG Shafer</name></author><author><name sortKey="Elzay, Rp" uniqKey="Elzay R">RP Elzay</name></author><author><name sortKey="Kerr, Da" uniqKey="Kerr D">DA Kerr</name></author><author><name sortKey="Corio, Rl" uniqKey="Corio R">RL Corio</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haghighat, K" uniqKey="Haghighat K">K Haghighat</name></author><author><name sortKey="Kalmar, Jr" uniqKey="Kalmar J">JR Kalmar</name></author><author><name sortKey="Mariotti, Aj" uniqKey="Mariotti A">AJ Mariotti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schwartz Arad, D" uniqKey="Schwartz Arad D">D Schwartz-Arad</name></author><author><name sortKey="Lustmann, J" uniqKey="Lustmann J">J Lustmann</name></author><author><name sortKey="Ulmansky, M" uniqKey="Ulmansky M">M Ulmansky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baden, E" uniqKey="Baden E">E Baden</name></author><author><name sortKey="Doyle, J" uniqKey="Doyle J">J Doyle</name></author><author><name sortKey="Mesa, M" uniqKey="Mesa M">M Mesa</name></author><author><name sortKey="Fabie, M" uniqKey="Fabie M">M Fabié</name></author><author><name sortKey="Lederman, D" uniqKey="Lederman D">D Lederman</name></author><author><name sortKey="Eichen, M" uniqKey="Eichen M">M Eichen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, K" uniqKey="Kim K">K Kim</name></author><author><name sortKey="Mintz, Sm" uniqKey="Mintz S">SM Mintz</name></author><author><name sortKey="Stevens, J" uniqKey="Stevens J">J Stevens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barrios, Tj" uniqKey="Barrios T">TJ Barrios</name></author><author><name sortKey="Sudol, Jc" uniqKey="Sudol J">JC Sudol</name></author><author><name sortKey="Cleveland, Db" uniqKey="Cleveland D">DB Cleveland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leider, As" uniqKey="Leider A">AS Leider</name></author><author><name sortKey="Jonker, La" uniqKey="Jonker L">LA Jonker</name></author><author><name sortKey="Cook, He" uniqKey="Cook H">HE Cook</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carr, Rf" uniqKey="Carr R">RF Carr</name></author><author><name sortKey="Carlton, Dm" uniqKey="Carlton D">DM Carlton</name></author><author><name sortKey="Marks, Rb" uniqKey="Marks R">RB Marks</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Favia, Gf" uniqKey="Favia G">GF Favia</name></author><author><name sortKey="Di Albert, L" uniqKey="Di Albert L">L Di Albert</name></author><author><name sortKey="Scarano, A" uniqKey="Scarano A">A Scarano</name></author><author><name sortKey="Piattelli, A" uniqKey="Piattelli A">A Piattelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcneill, J" uniqKey="Mcneill J">J McNeill</name></author><author><name sortKey="Price, Hm" uniqKey="Price H">HM Price</name></author><author><name sortKey="Stoker, Ng" uniqKey="Stoker N">NG Stoker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tatemoto, Y" uniqKey="Tatemoto Y">Y Tatemoto</name></author><author><name sortKey="Okada, Y" uniqKey="Okada Y">Y Okada</name></author><author><name sortKey="Mori, M" uniqKey="Mori M">M Mori</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yamada, K" uniqKey="Yamada K">K Yamada</name></author><author><name sortKey="Tatemoto, Y" uniqKey="Tatemoto Y">Y Tatemoto</name></author><author><name sortKey="Okada, Y" uniqKey="Okada Y">Y Okada</name></author><author><name sortKey="Mori, M" uniqKey="Mori M">M Mori</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ruhin, B" uniqKey="Ruhin B">B Ruhin</name></author><author><name sortKey="Raoul, G" uniqKey="Raoul G">G Raoul</name></author><author><name sortKey="Kolb, F" uniqKey="Kolb F">F Kolb</name></author><author><name sortKey="Casiraghi, O" uniqKey="Casiraghi O">O Casiraghi</name></author><author><name sortKey="Lecomte Houcke, M" uniqKey="Lecomte Houcke M">M Lecomte-Houcke</name></author><author><name sortKey="Ghoul, S" uniqKey="Ghoul S">S Ghoul</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Jy" uniqKey="Kim J">JY Kim</name></author><author><name sortKey="Kim, Jc" uniqKey="Kim J">JC Kim</name></author><author><name sortKey="Cho, Bo" uniqKey="Cho B">BO Cho</name></author><author><name sortKey="Kim, Sg" uniqKey="Kim S">SG Kim</name></author><author><name sortKey="Yang, Be" uniqKey="Yang B">BE Yang</name></author><author><name sortKey="Rataru, H" uniqKey="Rataru H">H Rataru</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ide, F" uniqKey="Ide F">F Ide</name></author><author><name sortKey="Shimoyama, T" uniqKey="Shimoyama T">T Shimoyama</name></author><author><name sortKey="Horie, N" uniqKey="Horie N">N Horie</name></author><author><name sortKey="Shimizu, S" uniqKey="Shimizu S">S Shimizu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Doyle, Jl" uniqKey="Doyle J">JL Doyle</name></author><author><name sortKey="Grodjesk, Je" uniqKey="Grodjesk J">JE Grodjesk</name></author><author><name sortKey="Dolinsky, Hb" uniqKey="Dolinsky H">HB Dolinsky</name></author><author><name sortKey="Rafel, Ss" uniqKey="Rafel S">SS Rafel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hopper, Tl" uniqKey="Hopper T">TL Hopper</name></author><author><name sortKey="Sadeghi, Em" uniqKey="Sadeghi E">EM Sadeghi</name></author><author><name sortKey="Pricco, Df" uniqKey="Pricco D">DF Pricco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leventon, Gs" uniqKey="Leventon G">GS Leventon</name></author><author><name sortKey="Happonen, Rp" uniqKey="Happonen R">RP Happonen</name></author><author><name sortKey="Newland, Jr" uniqKey="Newland J">JR Newland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kangvonkit, P" uniqKey="Kangvonkit P">P Kangvonkit</name></author><author><name sortKey="Sirichitra, V" uniqKey="Sirichitra V">V Sirichitra</name></author><author><name sortKey="Hansasuta, C" uniqKey="Hansasuta C">C Hansasuta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goldblatt, Li" uniqKey="Goldblatt L">LI Goldblatt</name></author><author><name sortKey="Brannon, Rb" uniqKey="Brannon R">RB Brannon</name></author><author><name sortKey="Ellis, Gl" uniqKey="Ellis G">GL Ellis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cataldo, E" uniqKey="Cataldo E">E Cataldo</name></author><author><name sortKey="Less, Wc" uniqKey="Less W">WC Less</name></author><author><name sortKey="Giunta, Jl" uniqKey="Giunta J">JL Giunta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Swan, Rh" uniqKey="Swan R">RH Swan</name></author><author><name sortKey="Mcdaniel, Rk" uniqKey="Mcdaniel R">RK McDaniel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Norris, Lh" uniqKey="Norris L">LH Norris</name></author><author><name sortKey="Baghaei Rad, M" uniqKey="Baghaei Rad M">M Baghaei-Rad</name></author><author><name sortKey="Maloney, Pl" uniqKey="Maloney P">PL Maloney</name></author><author><name sortKey="Simpson, G" uniqKey="Simpson G">G Simpson</name></author><author><name sortKey="Guinta, J" uniqKey="Guinta J">J Guinta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kristensen, S" uniqKey="Kristensen S">S Kristensen</name></author><author><name sortKey="Andersen, J" uniqKey="Andersen J">J Andersen</name></author><author><name sortKey="Jacobsen, P" uniqKey="Jacobsen P">P Jacobsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Monteil, Ra" uniqKey="Monteil R">RA Monteil</name></author><author><name sortKey="Terestri, P" uniqKey="Terestri P">P Terestri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Warnock, Gr" uniqKey="Warnock G">GR Warnock</name></author><author><name sortKey="Pierce, Gl" uniqKey="Pierce G">GL Pierce</name></author><author><name sortKey="Correll, Rw" uniqKey="Correll R">RW Correll</name></author><author><name sortKey="Baker, Da" uniqKey="Baker D">DA Baker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mills, Wp" uniqKey="Mills W">WP Mills</name></author><author><name sortKey="Davila, Ma" uniqKey="Davila M">MA Davila</name></author><author><name sortKey="Beuttenmuller, Ea" uniqKey="Beuttenmuller E">EA Beuttenmuller</name></author><author><name sortKey="Koudelka, Bm" uniqKey="Koudelka B">BM Koudelka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yaacob, Hb" uniqKey="Yaacob H">HB Yaacob</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Saxby, Ms" uniqKey="Saxby M">MS Saxby</name></author><author><name sortKey="Rippin, Jw" uniqKey="Rippin J">JW Rippin</name></author><author><name sortKey="Sheron, Je" uniqKey="Sheron J">JE Sheron</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="case-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Oral Maxillofac Pathol</journal-id><journal-id journal-id-type="publisher-id">JOMFP</journal-id><journal-title-group><journal-title>Journal of Oral and Maxillofacial Pathology : JOMFP</journal-title></journal-title-group><issn pub-type="ppub">0973-029X</issn><issn pub-type="epub">1998-393X</issn><publisher><publisher-name>Medknow Publications & Media Pvt Ltd</publisher-name><publisher-loc>India</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">22438650</article-id><article-id pub-id-type="pmc">3303503</article-id><article-id pub-id-type="publisher-id">JOMFP-16-113</article-id><article-id pub-id-type="doi">10.4103/0973-029X.92986</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Squamous odontogenic tumor: A case report and review of literature</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Badni</surname><given-names>Manjunath</given-names></name><xref ref-type="aff" rid="aff1"></xref><xref ref-type="corresp" rid="cor1"></xref></contrib><contrib contrib-type="author"><name><surname>Nagaraja</surname><given-names>A</given-names></name><xref ref-type="aff" rid="aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Kamath</surname><given-names>VV</given-names></name><xref ref-type="aff" rid="aff1"></xref></contrib></contrib-group><aff id="aff1"><italic>Department of Oral and Maxillofacial Pathology, Dr. Syamala Reddy Dental College, Hospital and Research Centre, Bangalore, India</italic></aff><author-notes><corresp id="cor1"><bold>Address for correspondence:</bold><italic> Dr. Manjunath Badni, Department of Oral Pathology and Microbiology, Sardar Patel Post Graduate Institute of Dental and Medical Sciences, Chaudhary Vihar, Raebareli Road, Lucknow - 226 025, Uttar Pradesh, India. E-mail: <email xlink:href="badni_manju@yahoo.com">badni_manju@yahoo.com</email></italic></corresp></author-notes><pub-date pub-type="ppub"><season>Jan-Apr</season><year>2012</year></pub-date><volume>16</volume><issue>1</issue><fpage>113</fpage><lpage>117</lpage><permissions><copyright-statement>Copyright: © Journal of Oral and Maxillofacial Pathology</copyright-statement><copyright-year>2012</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p>The squamous odontogenic tumor (SOT) is a rare, benign, locally infiltrative neoplasm of the jaws that appears to originate from the rests of Malassez, gingival surface epithelium or from remnants of the dental lamina. SOT was first described by Pullon <italic>et al</italic>. (1975). Since then there has been paucity in the number of reported cases, especially in the Indian subcontinent. The tumor is often asymptomatic, although it can present with symptoms of pain and tooth mobility. The characteristic radiographic appearance is that of a triangular-shaped unilocular radiolucency associated with the roots of erupted, vital teeth and has a predilection for the anterior maxilla and the posterior mandible. Histologically, the tumor is characterized by the formation of variably sized nests and cords of uniform, benign-appearing, squamous epithelium with occasional vacuolization and keratinization. We report a case of SOT occurring in a 58-year-old male in the anterior mandible with unusual localization and appearance.</p></abstract><kwd-group><kwd>Odontogenic tumor</kwd><kwd>rests of Malassez</kwd><kwd>squamous cells</kwd></kwd-group></article-meta></front><body><sec id="sec1-1"><title>INTRODUCTION</title><p>Squamous odontogenic tumor (SOT) is a lesion which had been recognized as an apparent entity for a number of years until 1975, when Pullon and coworkers published a series of six cases.[<xref ref-type="bibr" rid="ref1">1</xref>] SOT has been defined as a benign but locally infiltrative neoplasm consisting of islands of well-differentiated squamous epithelium in a fibrous stroma. The epithelial islands occasionally show foci of central cystic degeneration.[<xref ref-type="bibr" rid="ref2">2</xref>] SOT is a rare, benign but locally infiltrative epithelial tumor that supposedly develops from the remnants of dental lamina, or of the cell rests of Malassez (ROM), or gingival epithelium.[<xref ref-type="bibr" rid="ref3">3</xref>]</p><p>To date, fewer than 50 cases have been reported in the literature. The most common site of occurrence of the lesion in the mandible is the bicuspid-molar region and in the maxilla, incisor-cuspid area. Radiographically, SOT often exhibits a characteristic unilocular and triangular-shaped radiolucency of the alveolar bone, with the wide base of the radiolucency localized between the diverging apices of the adjacent roots.[<xref ref-type="bibr" rid="ref4">4</xref>] Histologically, the tumor is characterized by multiple islands of squamous epithelium surrounded by a mature connective tissue stroma. Cystic degeneration or calcification may occasionally be observed in the epithelial islands.[<xref ref-type="bibr" rid="ref5">5</xref>] The usual treatment has been simple enucleation and recurrence has been rare.[<xref ref-type="bibr" rid="ref6">6</xref>] The purpose of this article is to report a new case and review the literature.</p></sec><sec id="sec1-2"><title>CASE REPORT</title><p>A 58-year-old male patient reported to our dental hospital with a complaint of swelling and mobility of teeth in the right anterior region of mandible from past 3 months. Onset occurred 3 months ago and it was asymptomatic. Medical history of patient was unremarkable. Clinical examination revealed a firm anterior swelling in right central and lateral incisor region of mandible. The mandibular right central incisor and canine were mobile. Radiograph [<xref ref-type="fig" rid="F1">Figure 1</xref>] showed radiolucency with severe alveolar bone loss localized between right lateral and central incisor region of mandible, which was associated with markedly diverging roots. Based on the clinical and radiographic findings, the initial diagnosis of periodontosis was made and subjected for histologic examination. Histological examination [Figures <xref ref-type="fig" rid="F2">2</xref>–<xref ref-type="fig" rid="F4">4</xref>] revealed a proliferation of mature stratified squamous epithelial islands in a dense fibrous connective stroma and the diagnosis of SOT was confirmed.</p><fig id="F1" position="float"><label>Figure 1</label><caption><p>Panoromic radiograph reveals triangular radiolucent area involving roots of mandibular right central and lateral incisor</p></caption><graphic xlink:href="JOMFP-16-113-g001"></graphic></fig><fig id="F2" position="float"><label>Figure 2</label><caption><p>Photomicrograph revealing scattered islands of squamous epithelium in a dense fibrous connective tissue stroma (H and E, stain ×4 magnification)</p></caption><graphic xlink:href="JOMFP-16-113-g002"></graphic></fig><fig id="F3" position="float"><label>Figure 3</label><caption><p>Photomicrograph revealing an island of benign squamous epithelium without presence of peripheral columnar cells, palisading nuclei or stellate reticulum (H and E, stain ×10 magnification)</p></caption><graphic xlink:href="JOMFP-16-113-g003"></graphic></fig><fig id="F4" position="float"><label>Figure 4</label><caption><p>Photomicrograph of an epithelial island composed of uniform squamous epithelial cells (H and E, stain ×40 magnification)</p></caption><graphic xlink:href="JOMFP-16-113-g004"></graphic></fig></sec><sec id="sec1-3"><title>DISCUSSION</title><p>After Pullon <italic>et al</italic>. had described an entity named SOT, a number of additional cases have been reported in the literature.[<xref ref-type="bibr" rid="ref3">3</xref>] To date, 44 cases of SOT have been reported [<xref ref-type="table" rid="T1">Table 1</xref>]. Due to the paucity of documented cases of SOT, the relative frequency among odontogenic tumors cannot be stated.[<xref ref-type="bibr" rid="ref2">2</xref>] SOT is known to occur in a wide age range, from first decade to eighth decade of life, with mean age of occurrence being 38.2 years. The gender ratio among 44 cases being 1:1.8 (F:M) showing slightly more predilection among males [<xref ref-type="table" rid="T1">Table 1</xref>].</p><table-wrap id="T1" position="float"><label>Table 1</label><caption><p>Summary of reported cases of SOT</p></caption><graphic xlink:href="JOMFP-16-113-g005"></graphic></table-wrap><p>Out of the 44 cases excluding our case, 20 have been located in posterior region of mandible. In maxilla, SOT occurred most commonly in canine-first premolar area.[<xref ref-type="bibr" rid="ref7">7</xref>] Our case is unique in that it is the first case reported in the Indian literature and second ever case to occur between the roots of central and lateral incisors in the anterior segment of the mandible. Hence, the most common location for development of an SOT in the maxilla is anterior region and posterior in case of mandible with almost equal propensity to occur in both the jaws.[<xref ref-type="bibr" rid="ref7">7</xref>] SOTs occurring in maxilla were found to be more aggressive than in mandible.[<xref ref-type="bibr" rid="ref2">2</xref><xref ref-type="bibr" rid="ref6">6</xref>] This was mainly due to the anatomy, porous and medullary nature of bone.[<xref ref-type="bibr" rid="ref8">8</xref>] Leider <italic>et al</italic>. reported a rare familial tendency for this neoplasm.[<xref ref-type="bibr" rid="ref9">9</xref>]</p><p>Most of the cases arise and develop in the periodontium of permanent dentition. One case was associated with the deciduous dentition and four cases were detected in edentulous areas.[<xref ref-type="bibr" rid="ref2">2</xref>–<xref ref-type="bibr" rid="ref3">3</xref><xref ref-type="bibr" rid="ref5">5</xref>]</p><p>Clinical presentation of SOTs represented a slow growing, intrabony lesion with very few clinical signs and symptoms. Most common being mobility of adjacent teeth, swelling of alveolar process, and mild/moderate pain in the affected areas. However, lesion may be asymptomatic and detected in routine intraoral radiographs.[<xref ref-type="bibr" rid="ref8">8</xref>]</p><p>Radiograph of common central variant of SOT shows a well-defined unilocular, triangular radiolucency between the roots of adjacent teeth. Root resorption, radiopacities seen in other odontogenic neoplasms are seldom a feature of SOT. Large and extensive SOTs may, however, show multilocular pattern. Root resorption was noticed in only one case.[<xref ref-type="bibr" rid="ref10">10</xref>] The peripheral variant may cause some saucerization of underlying bone. This was likely to be a pressure phenomenon rather than the result of true tumor infiltration.[<xref ref-type="bibr" rid="ref2">2</xref>]</p><p>Histologically, the lesion usually presents as islands of benign squamous epithelium in mature connective tissue stroma without the evidence of peripheral columnar cells, palisading nuclei, or stellate reticulum. The epithelial islands of SOT seem to resemble the squamous metaplasia seen in ameloblastoma; however, the lack of peripheral columnar cells and palisading nuclei establishes the differential diagnosis between these two tumors. Moreover, it must be distinguished from primary intraosseous squamous cell carcinoma, which is rare in young persons and presents dysplastic epithelial features.[<xref ref-type="bibr" rid="ref11">11</xref>] Keratin pearls, microcysts, and intraepithelial calcification are often present in SOTs. Circular areas of fibroblast and fibrous condensation/hyalinization can be seen around some of the epithelial islands, which suggests a connective tissue reaction to epithelial proliferation.[<xref ref-type="bibr" rid="ref7">7</xref>]</p><p>In one of the reported cases, electron microscopy showed epithelial cells with features similar to cells of stratum spinosum with numerous desmosomes, abundant glycogen granules, tonofilaments, and myelin bodies.[<xref ref-type="bibr" rid="ref12">12</xref>]</p><p>The pathogenesis of SOT has yet remained unclear. The epithelial odontogenic tumors are histologically related to remnants of odontogenic epithelium, which includes the dental lamina (cell rests of Serre), enamel organ, and the root sheath of Hertwig (cell ROM). Actively growing dental lamina is present within the jaws for a considerable time after birth. Because of the widespread presence of odontogenic epithelium, some tumors may arise from residues of these cells in bone or in soft tissues such as the gingiva. Regarding the pathogenesis of SOT, most researchers have pointed toward a periodontal ligament origin for the central variant of the lesion. Radiographic appearance of the lesion, occurring between the adjacent teeth in the tooth bearing area from the periodontal ligament space, and the pattern of bone destruction seeming to emanate relatively uniformly from the areas of tooth roots lend credence to the theory of origin from the periodontal ligament, viz., from the ROM. Microscopic findings, the epithelial islands which are intimately associated with the apices of the retained teeth, and tight adherence of tumor mass to the canine and ease of separation from the buccal soft tissue further add to the notion of origin from ROM. The ROM hitherto considered to be resting cells in the periodontal ligament have received much of attention recently. It is known that the ROM persists into adult life in all areas of the periodontal ligament but most abundantly in the area of the cervical half of the root where some have even proliferated and formed structures within the periodontal ligament similar to rests of Serre. The fact that some cases are reported in edentulous areas does not take away the possibility that they originated from ROM of teeth formerly present.[<xref ref-type="bibr" rid="ref4">4</xref><xref ref-type="bibr" rid="ref9">9</xref>]</p><p>The heightened activity in nonperiodontal lesions can perhaps be attributed to certain genetic etiologies. The ameloblastin gene, for example, has been shown to express an important protein in epithelial-mesenchymal signaling during odontogenesis, and mutations of this gene have been found in SOT, Adenomatoid Odontogenic Tumor and Ameloblastomas. Further investigations need to be done to see if mutations in this gene have a vital role in tumorigenesis of SOT. In addition, the heparanase gene, which codes for an enzyme that is important in dissemination and cellular invasion, is prevalent in ameloblastomas. The production of heparanase was thought to contribute to its local invasiveness. Further studies with heparanase in other locally invasive lesions such as SOTs can perhaps be performed to establish additional genetic influences related to the aggressiveness of some of SOTs reported recently.[<xref ref-type="bibr" rid="ref7">7</xref>]</p><p>Carr <italic>et al</italic>. postulated a gingival origin for the SOTs and observed that the insular growth pattern of the tumor, the presence of squamous cells with clear cytoplasm, the parakeratosis, and the tendency to microcyst formation were related to gingival rests of Serres.[<xref ref-type="bibr" rid="ref10">10</xref>]</p><p>Proliferation of squamous epithelial islands in SOT has also been reported in submucosal regions, which might indicate that the lesion originates from the rests of Serres. However, it should be recognized that there are peripheral variants of SOT that are thought to arise from gingival surface epithelium or from remnants of the dental lamina (rests of Serres).[<xref ref-type="bibr" rid="ref10">10</xref>]</p><p>SOT-like proliferations (SOT-LP) have been reported in fewer than 15 cases, arising from the walls of the odontogenic cysts. These lesions were cystic by nature, although histologically were similar to SOT, they exhibited no tendency to evolve into neoplasms. SOT-LP exhibited varying clinical, radiological, and prognostic features than true SOTs. Biologically, SOTs are less aggressive than ameloblastomas but are more aggressive than SOT-LP in the cysts, except for those arising from the walls of odontogenic keratocysts.[<xref ref-type="bibr" rid="ref9">9</xref>]</p><p>Immunohistochemical studies conducted by Tatemoto <italic>et al</italic>. and Yamada <italic>et al</italic>. on SOT confirmed the proliferative activity of odontogenic epithelium indicated by heavy staining for keratin 13/16, and squamous differentiating cells in the center of tumor islands have shown a strong positive reaction for involucrin staining.[<xref ref-type="bibr" rid="ref13">13</xref><xref ref-type="bibr" rid="ref14">14</xref>]</p><p>Treatment of SOT involves conservative local excision, curettage, enucleation, and scaling of adjacent teeth.[<xref ref-type="bibr" rid="ref2">2</xref><xref ref-type="bibr" rid="ref8">8</xref>] Recurrences have been reported in only one case, most likely due to insufficient initial removal.[<xref ref-type="bibr" rid="ref8">8</xref>]</p><p>Ide <italic>et al</italic>. suggested that SOT could transform into a malignant disorder such as intraosseous squamous cell carcinoma.[<xref ref-type="bibr" rid="ref17">17</xref>] King Kim <italic>et al</italic>. suggested that SOT can decorticate the dense bone of mandible and may impact the therapeutic modalities and diagnosis management of these presumed innocuous lesion.[<xref ref-type="bibr" rid="ref7">7</xref>]</p><p>SOT is a benign odontogenic neoplasm of distinctive histological features probably arising from ROM, although three decades have passed since the establishment of the lesion as a separate entity much remains to be learned about the SOT. The sporadic reports in the literature belie the propensity of the lesion to occur in the jaws. A probable reason could be the comparative few reports and the common mistaken diagnosis of an acanthomatous ameloblastoma.</p></sec></body><back><fn-group><fn fn-type="supported-by"><p><bold>Source of Support:</bold> Nil.</p></fn><fn fn-type="conflict"><p><bold>Conflict of Interest:</bold> None declared.</p></fn></fn-group><ref-list><title>REFERENCES</title><ref id="ref1"><label>1</label><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Rajendran</surname><given-names>R</given-names></name></person-group><person-group person-group-type="editor"><name><surname>Rajendran</surname><given-names>R</given-names></name><name><surname>Sivapathasundharam</surname><given-names>B</given-names></name></person-group><article-title>Cyst and Tumors of Odontogenic Origin</article-title><source>Shafer's Text Book of Oral Pathology</source><year>2005</year><edition>5th ed</edition><publisher-loc>Noida</publisher-loc><publisher-name>Elservier</publisher-name><fpage>398</fpage><lpage>400</lpage></element-citation></ref><ref id="ref2"><label>2</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Philipsen</surname><given-names>HP</given-names></name><name><surname>Reichart</surname><given-names>PA</given-names></name></person-group><article-title>Squamous odontogenic tumor (SOT): A benign neoplasm of the periodontium A review of 36 reported cases</article-title><source>J Clin Periodontol</source><year>1996</year><volume>23</volume><fpage>922</fpage><lpage>6</lpage><pub-id pub-id-type="pmid">8915020</pub-id></element-citation></ref><ref id="ref3"><label>3</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Pullon</surname><given-names>PA</given-names></name><name><surname>Shafer</surname><given-names>WG</given-names></name><name><surname>Elzay</surname><given-names>RP</given-names></name><name><surname>Kerr</surname><given-names>DA</given-names></name><name><surname>Corio</surname><given-names>RL</given-names></name></person-group><article-title>Squamous odontogenic tumour. Report of six cases of a previously undescribed lesion</article-title><source>Oral Surg Oral Med Oral Pathol</source><year>1975</year><volume>40</volume><fpage>616</fpage><lpage>30</lpage><pub-id pub-id-type="pmid">1059063</pub-id></element-citation></ref><ref id="ref4"><label>4</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Haghighat</surname><given-names>K</given-names></name><name><surname>Kalmar</surname><given-names>JR</given-names></name><name><surname>Mariotti</surname><given-names>AJ</given-names></name></person-group><article-title>Squamous odontogenic tumor: Diagnosis and management</article-title><source>J Periodontol</source><year>2002</year><volume>73</volume><fpage>653</fpage><lpage>6</lpage><pub-id pub-id-type="pmid">12083539</pub-id></element-citation></ref><ref id="ref5"><label>5</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Schwartz-Arad</surname><given-names>D</given-names></name><name><surname>Lustmann</surname><given-names>J</given-names></name><name><surname>Ulmansky</surname><given-names>M</given-names></name></person-group><article-title>Squamous odontogenic tumour. Review of literature and case report</article-title><source>Int J Oral Maxillofac Surg</source><year>1990</year><volume>19</volume><fpage>327</fpage><lpage>30</lpage><pub-id pub-id-type="pmid">2128306</pub-id></element-citation></ref><ref id="ref6"><label>6</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Baden</surname><given-names>E</given-names></name><name><surname>Doyle</surname><given-names>J</given-names></name><name><surname>Mesa</surname><given-names>M</given-names></name><name><surname>Fabié</surname><given-names>M</given-names></name><name><surname>Lederman</surname><given-names>D</given-names></name><name><surname>Eichen</surname><given-names>M</given-names></name></person-group><article-title>Squamous odontogenic tumour. Report of three cases including the first extraosseous case</article-title><source>Oral Surg Oral Med Oral Pathol</source><year>1993</year><volume>75</volume><fpage>733</fpage><lpage>8</lpage><pub-id pub-id-type="pmid">8515987</pub-id></element-citation></ref><ref id="ref7"><label>7</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kim</surname><given-names>K</given-names></name><name><surname>Mintz</surname><given-names>SM</given-names></name><name><surname>Stevens</surname><given-names>J</given-names></name></person-group><article-title>Squamous odontogenic tumour causing erosion of the lingual cortical plate in the mandible: A report of 2 cases</article-title><source>J Oral Maxillofac Surg</source><year>2007</year><volume>65</volume><fpage>1227</fpage><lpage>31</lpage><pub-id pub-id-type="pmid">17517311</pub-id></element-citation></ref><ref id="ref8"><label>8</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Barrios</surname><given-names>TJ</given-names></name><name><surname>Sudol</surname><given-names>JC</given-names></name><name><surname>Cleveland</surname><given-names>DB</given-names></name></person-group><article-title>Squamous odontogenic tumor associated with an erupting maxillary canine: Case report</article-title><source>J Oral Maxillofac Surg</source><year>2004</year><volume>62</volume><fpage>742</fpage><lpage>4</lpage><pub-id pub-id-type="pmid">15170290</pub-id></element-citation></ref><ref id="ref9"><label>9</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Leider</surname><given-names>AS</given-names></name><name><surname>Jonker</surname><given-names>LA</given-names></name><name><surname>Cook</surname><given-names>HE</given-names></name></person-group><article-title>Multicentric familial squamous odontogenic tumour</article-title><source>Oral Surg Oral Med Oral Pathol</source><year>1989</year><volume>68</volume><fpage>175</fpage><lpage>81</lpage><pub-id pub-id-type="pmid">2674829</pub-id></element-citation></ref><ref id="ref10"><label>10</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Carr</surname><given-names>RF</given-names></name><name><surname>Carlton</surname><given-names>DM</given-names><suffix>Jr</suffix></name><name><surname>Marks</surname><given-names>RB</given-names></name></person-group><article-title>Squamous odontogenic tumor: Report of case</article-title><source>J Oral Surg</source><year>1981</year><volume>39</volume><fpage>297</fpage><lpage>8</lpage><pub-id pub-id-type="pmid">6937627</pub-id></element-citation></ref><ref id="ref11"><label>11</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Favia</surname><given-names>GF</given-names></name><name><surname>Di Albert</surname><given-names>L</given-names></name><name><surname>Scarano</surname><given-names>A</given-names></name><name><surname>Piattelli</surname><given-names>A</given-names></name></person-group><article-title>Squamous odontogenic tumour: Report of two cases</article-title><source>Oral Oncol</source><year>1997</year><volume>33</volume><fpage>451</fpage><lpage>3</lpage><pub-id pub-id-type="pmid">9509132</pub-id></element-citation></ref><ref id="ref12"><label>12</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>McNeill</surname><given-names>J</given-names></name><name><surname>Price</surname><given-names>HM</given-names></name><name><surname>Stoker</surname><given-names>NG</given-names></name></person-group><article-title>Squamous odontogenic tumor: Report of case with long-term history</article-title><source>J Oral Surg</source><year>1980</year><volume>38</volume><fpage>466</fpage><lpage>71</lpage><pub-id pub-id-type="pmid">6154792</pub-id></element-citation></ref><ref id="ref13"><label>13</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Tatemoto</surname><given-names>Y</given-names></name><name><surname>Okada</surname><given-names>Y</given-names></name><name><surname>Mori</surname><given-names>M</given-names></name></person-group><article-title>Squamous odontogenic tumor: Immunohistochemical identification of keratins</article-title><source>Oral Surg Oral Med Oral Pathol</source><year>1989</year><volume>67</volume><fpage>63</fpage><lpage>7</lpage><pub-id pub-id-type="pmid">2463509</pub-id></element-citation></ref><ref id="ref14"><label>14</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Yamada</surname><given-names>K</given-names></name><name><surname>Tatemoto</surname><given-names>Y</given-names></name><name><surname>Okada</surname><given-names>Y</given-names></name><name><surname>Mori</surname><given-names>M</given-names></name></person-group><article-title>Immunostaining of involucrin in odontogenic epithelial tumors and cysts</article-title><source>Oral Surg Oral Med Oral Pathol</source><year>1989</year><volume>67</volume><fpage>564</fpage><lpage>8</lpage><pub-id pub-id-type="pmid">2470003</pub-id></element-citation></ref><ref id="ref15"><label>15</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ruhin</surname><given-names>B</given-names></name><name><surname>Raoul</surname><given-names>G</given-names></name><name><surname>Kolb</surname><given-names>F</given-names></name><name><surname>Casiraghi</surname><given-names>O</given-names></name><name><surname>Lecomte-Houcke</surname><given-names>M</given-names></name><name><surname>Ghoul</surname><given-names>S</given-names></name><etal></etal></person-group><article-title>Aggressive maxillary squamous odontogenic tumour in a child: Histological dilemma and adaptive surgical behavior</article-title><source>Int J Oral Maxillofac Surg</source><year>2007</year><volume>36</volume><fpage>864</fpage><lpage>6</lpage><pub-id pub-id-type="pmid">17509831</pub-id></element-citation></ref><ref id="ref16"><label>16</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kim</surname><given-names>JY</given-names></name><name><surname>Kim</surname><given-names>JC</given-names></name><name><surname>Cho</surname><given-names>BO</given-names></name><name><surname>Kim</surname><given-names>SG</given-names></name><name><surname>Yang</surname><given-names>BE</given-names></name><name><surname>Rataru</surname><given-names>H</given-names></name></person-group><article-title>Squamous odontogenic tumor: A case report and review of literature</article-title><source>J Korean Assoc Oral Maxillofac Surg</source><year>2007</year><volume>33</volume><fpage>59</fpage><lpage>2</lpage></element-citation></ref><ref id="ref17"><label>17</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ide</surname><given-names>F</given-names></name><name><surname>Shimoyama</surname><given-names>T</given-names></name><name><surname>Horie</surname><given-names>N</given-names></name><name><surname>Shimizu</surname><given-names>S</given-names></name></person-group><article-title>Intraosseous squamous cell carcinoma arising in association with a squamous odontogenic tumour of the mandible</article-title><source>Oral Oncol</source><year>1999</year><volume>35</volume><fpage>431</fpage><lpage>4</lpage><pub-id pub-id-type="pmid">10645411</pub-id></element-citation></ref><ref id="ref18"><label>18</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Doyle</surname><given-names>JL</given-names></name><name><surname>Grodjesk</surname><given-names>JE</given-names></name><name><surname>Dolinsky</surname><given-names>HB</given-names></name><name><surname>Rafel</surname><given-names>SS</given-names></name></person-group><article-title>Squamous odontogenic tumor: Report of three cases</article-title><source>J Oral Surg</source><year>1977</year><volume>35</volume><fpage>994</fpage><lpage>6</lpage><pub-id pub-id-type="pmid">270569</pub-id></element-citation></ref><ref id="ref19"><label>19</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hopper</surname><given-names>TL</given-names></name><name><surname>Sadeghi</surname><given-names>EM</given-names></name><name><surname>Pricco</surname><given-names>DF</given-names></name></person-group><article-title>Squamous odontogenic tumor: Report of a case with multiple lesions</article-title><source>Oral Surg Oral Med Oral Pathol</source><year>1980</year><volume>50</volume><fpage>404</fpage><lpage>10</lpage><pub-id pub-id-type="pmid">6935595</pub-id></element-citation></ref><ref id="ref20"><label>20</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Leventon</surname><given-names>GS</given-names></name><name><surname>Happonen</surname><given-names>RP</given-names></name><name><surname>Newland</surname><given-names>JR</given-names></name></person-group><article-title>Squamous odontogenic tumor</article-title><source>Am J Surg Pathol</source><year>1981</year><volume>5</volume><fpage>671</fpage><lpage>7</lpage><pub-id pub-id-type="pmid">7337159</pub-id></element-citation></ref><ref id="ref21"><label>21</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kangvonkit</surname><given-names>P</given-names></name><name><surname>Sirichitra</surname><given-names>V</given-names></name><name><surname>Hansasuta</surname><given-names>C</given-names></name></person-group><article-title>Squamous odontogenic tumor (report of a case and review of the literature)</article-title><source>J Dent Assoc Thai</source><year>1981</year><volume>31</volume><fpage>25</fpage><lpage>33</lpage><pub-id pub-id-type="pmid">6943154</pub-id></element-citation></ref><ref id="ref22"><label>22</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Goldblatt</surname><given-names>LI</given-names></name><name><surname>Brannon</surname><given-names>RB</given-names></name><name><surname>Ellis</surname><given-names>GL</given-names></name></person-group><article-title>Squamous odontogenic tumor: Report of five cases and review of the literature</article-title><source>Oral Surg Oral Med Oral Pathol</source><year>1982</year><volume>54</volume><fpage>187</fpage><lpage>96</lpage><pub-id pub-id-type="pmid">6956838</pub-id></element-citation></ref><ref id="ref23"><label>23</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Cataldo</surname><given-names>E</given-names></name><name><surname>Less</surname><given-names>WC</given-names></name><name><surname>Giunta</surname><given-names>JL</given-names></name></person-group><article-title>Squamous odontogenic tumor: A lesion of the periodontium</article-title><source>J Periodontol</source><year>1983</year><volume>54</volume><fpage>731</fpage><lpage>5</lpage><pub-id pub-id-type="pmid">6580427</pub-id></element-citation></ref><ref id="ref24"><label>24</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Swan</surname><given-names>RH</given-names></name><name><surname>McDaniel</surname><given-names>RK</given-names></name></person-group><article-title>Squamous odontogenic proliferation with probable origin from the rests of Malassez (early squamous odontogenic tumor?)</article-title><source>J Periodontol</source><year>1983</year><volume>54</volume><fpage>493</fpage><lpage>6</lpage><pub-id pub-id-type="pmid">6578321</pub-id></element-citation></ref><ref id="ref25"><label>25</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Norris</surname><given-names>LH</given-names></name><name><surname>Baghaei-Rad</surname><given-names>M</given-names></name><name><surname>Maloney</surname><given-names>PL</given-names></name><name><surname>Simpson</surname><given-names>G</given-names></name><name><surname>Guinta</surname><given-names>J</given-names></name></person-group><article-title>Bilateral maxillary squamous odontogenic tumor and the malignant transformation of a mandibular radiolucent lesion</article-title><source>J Oral Maxillofac Surg</source><year>1984</year><volume>42</volume><fpage>827</fpage><lpage>34</lpage><pub-id pub-id-type="pmid">6594479</pub-id></element-citation></ref><ref id="ref26"><label>26</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kristensen</surname><given-names>S</given-names></name><name><surname>Andersen</surname><given-names>J</given-names></name><name><surname>Jacobsen</surname><given-names>P</given-names></name></person-group><article-title>Squamous odontogenic tumor: Review of literature and a new case</article-title><source>J Laryngol Otol</source><year>1985</year><volume>99</volume><fpage>919</fpage><lpage>24</lpage><pub-id pub-id-type="pmid">4045313</pub-id></element-citation></ref><ref id="ref27"><label>27</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Monteil</surname><given-names>RA</given-names></name><name><surname>Terestri</surname><given-names>P</given-names></name></person-group><article-title>Squamous odontogenic tumor related to an unerupted lower canine</article-title><source>J Oral Maxillofac Surg</source><year>1985</year><volume>43</volume><fpage>888</fpage><lpage>95</lpage><pub-id pub-id-type="pmid">3863901</pub-id></element-citation></ref><ref id="ref28"><label>28</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Warnock</surname><given-names>GR</given-names></name><name><surname>Pierce</surname><given-names>GL</given-names></name><name><surname>Correll</surname><given-names>RW</given-names></name><name><surname>Baker</surname><given-names>DA</given-names></name></person-group><article-title>Triangular-shaped radiolucent area between roots of the mandibular right canine and first premolar</article-title><source>J Am Dent Assoc</source><year>1985</year><volume>110</volume><fpage>945</fpage><lpage>6</lpage><pub-id pub-id-type="pmid">3860556</pub-id></element-citation></ref><ref id="ref29"><label>29</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Mills</surname><given-names>WP</given-names></name><name><surname>Davila</surname><given-names>MA</given-names></name><name><surname>Beuttenmuller</surname><given-names>EA</given-names></name><name><surname>Koudelka</surname><given-names>BM</given-names></name></person-group><article-title>Squamous odontogenic tumor: Report of a case with lesions in three quadrants</article-title><source>Oral Surg Oral Med Oral Pathol</source><year>1986</year><volume>61</volume><fpage>557</fpage><lpage>63</lpage><pub-id pub-id-type="pmid">3459983</pub-id></element-citation></ref><ref id="ref30"><label>30</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Yaacob</surname><given-names>HB</given-names></name></person-group><article-title>Squamous odontogenic tumor</article-title><source>J Nihon Univ Sch Dent</source><year>1990</year><volume>32</volume><fpage>187</fpage><lpage>91</lpage><pub-id pub-id-type="pmid">2230962</pub-id></element-citation></ref><ref id="ref31"><label>31</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Saxby</surname><given-names>MS</given-names></name><name><surname>Rippin</surname><given-names>JW</given-names></name><name><surname>Sheron</surname><given-names>JE</given-names></name></person-group><article-title>Case report: Squamous odontogenic tumor of the gingiva</article-title><source>J Periodontol</source><year>1993</year><volume>64</volume><fpage>1250</fpage><lpage>2</lpage><pub-id pub-id-type="pmid">8106954</pub-id></element-citation></ref></ref-list></back></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001E889 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 001E889 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.32. |  |