Cryosurgery (N2O) Application to Remove Lip Lesions of Lipoid Proteinosis Syndrome: A Case Report
Identifieur interne : 001D97 ( Pmc/Corpus ); précédent : 001D96; suivant : 001D98Cryosurgery (N2O) Application to Remove Lip Lesions of Lipoid Proteinosis Syndrome: A Case Report
Auteurs : Amir Mansour ShiraniSource :
- Journal of Dental Research, Dental Clinics, Dental Prospects [ 2008-210X ] ; 2008.
Abstract
Lipoid proteinosis is a rare hereditary metabolic disorder transmitted as an autosomal recessive trait. It is characterized by the deposition of an amorphous hyaline-like material (glycoprotein) in the mucous membranes, skin and various internal organs. Cryosurgery (N2O) was applied to remove and reshape the lip lesions in a case of this rare syndrome. The patient was a 24-year-old female. Cryosurgery (−63ºC N2O for one minute) was performed to re-shape some areas of the upper lip. The lips were softer and had better esthetics after treatment. The use of cryosurgery offers advantages over surgery in reshaping of the lip lesions in this syndrome, since suturing is not feasible in rigid mucosa of these patients.
Url:
DOI: 10.5681/joddd.2008.014
PubMed: 23289062
PubMed Central: 3532738
Links to Exploration step
PMC:3532738Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cryosurgery (N2O) Application to Remove Lip Lesions of Lipoid Proteinosis Syndrome: A Case Report</title><author><name sortKey="Shirani, Amir Mansour" sort="Shirani, Amir Mansour" uniqKey="Shirani A" first="Amir Mansour" last="Shirani">Amir Mansour Shirani</name><affiliation><nlm:aff id="A01">Assistant Professor, Department of Oral Medicine, Faculty of Dentistry, Isfahan University of Medical Sciences, Iran</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23289062</idno><idno type="pmc">3532738</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532738</idno><idno type="RBID">PMC:3532738</idno><idno type="doi">10.5681/joddd.2008.014</idno><date when="2008">2008</date><idno type="wicri:Area/Pmc/Corpus">001D97</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001D97</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Cryosurgery (N2O) Application to Remove Lip Lesions of Lipoid Proteinosis Syndrome: A Case Report</title><author><name sortKey="Shirani, Amir Mansour" sort="Shirani, Amir Mansour" uniqKey="Shirani A" first="Amir Mansour" last="Shirani">Amir Mansour Shirani</name><affiliation><nlm:aff id="A01">Assistant Professor, Department of Oral Medicine, Faculty of Dentistry, Isfahan University of Medical Sciences, Iran</nlm:aff></affiliation></author></analytic><series><title level="j">Journal of Dental Research, Dental Clinics, Dental Prospects</title><idno type="ISSN">2008-210X</idno><idno type="eISSN">2008-2118</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Lipoid proteinosis is a rare hereditary metabolic disorder transmitted as an autosomal recessive trait. It is characterized by the deposition of an amorphous hyaline-like material (glycoprotein) in the mucous membranes, skin and various internal organs. Cryosurgery (N<sub>2</sub>O) was applied to remove and reshape the lip lesions in a case of this rare syndrome.
The patient was a 24-year-old female. Cryosurgery (−63ºC N<sub>2</sub>O for one minute) was performed to re-shape some areas of the upper lip. The lips were softer and had better esthetics after treatment. The use of cryosurgery offers advantages over surgery in reshaping of the lip lesions in this syndrome, since suturing is not feasible in rigid mucosa of these patients.
</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Urbach, E" uniqKey="Urbach E">E Urbach</name></author><author><name sortKey="Wiethe, C" uniqKey="Wiethe C">C Wiethe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hamada, T" uniqKey="Hamada T">T Hamada</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Laskaris, G" uniqKey="Laskaris G">G Laskaris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hamada, T" uniqKey="Hamada T">T Hamada</name></author><author><name sortKey="Wessagowit, V" uniqKey="Wessagowit V">V Wessagowit</name></author><author><name sortKey="South, Ap" uniqKey="South A">AP South</name></author><author><name sortKey="Ashton, Gh" uniqKey="Ashton G">GH Ashton</name></author><author><name sortKey="Chan, I" uniqKey="Chan I">I Chan</name></author><author><name sortKey="Oyama, N" uniqKey="Oyama N">N Oyama</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bozda, Ke" uniqKey="Bozda K">KE Bozdağ</name></author><author><name sortKey="Gul, Y" uniqKey="Gul Y">Y Gül</name></author><author><name sortKey="Karaman, A" uniqKey="Karaman A">A Karaman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Disdier, P" uniqKey="Disdier P">P Disdier</name></author><author><name sortKey="Harle, Jr" uniqKey="Harle J">JR Harlé</name></author><author><name sortKey="Andrac, L" uniqKey="Andrac L">L Andrac</name></author><author><name sortKey="Swiader, L" uniqKey="Swiader L">L Swiader</name></author><author><name sortKey="Weiller, Pj" uniqKey="Weiller P">PJ Weiller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bazopoulou Kyrkanidou, E" uniqKey="Bazopoulou Kyrkanidou E">E Bazopoulou-Kyrkanidou</name></author><author><name sortKey="Tosios, Ki" uniqKey="Tosios K">KI Tosios</name></author><author><name sortKey="Zabelis, G" uniqKey="Zabelis G">G Zabelis</name></author><author><name sortKey="Charalampopoulou, S" uniqKey="Charalampopoulou S">S Charalampopoulou</name></author><author><name sortKey="Papanicolaou, Si" uniqKey="Papanicolaou S">SI Papanicolaou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Friedman, L" uniqKey="Friedman L">L Friedman</name></author><author><name sortKey="Mathews, Rd" uniqKey="Mathews R">RD Mathews</name></author><author><name sortKey="Swanepoel, Pd" uniqKey="Swanepoel P">PD Swanepoel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poswillo, D" uniqKey="Poswillo D">D Poswillo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, Ck" uniqKey="Wong C">CK Wong</name></author><author><name sortKey="Lin, Cs" uniqKey="Lin C">CS Lin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ozkaya Bayazit, E" uniqKey="Ozkaya Bayazit E">E Ozkaya-Bayazit</name></author><author><name sortKey="Ozarma An, G" uniqKey="Ozarma An G">G Ozarmağan</name></author><author><name sortKey="Baykal, C" uniqKey="Baykal C">C Baykal</name></author><author><name sortKey="Ulu, T" uniqKey="Ulu T">T Uluğ</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gruber, F" uniqKey="Gruber F">F Gruber</name></author><author><name sortKey="Manestar, D" uniqKey="Manestar D">D Manestar</name></author><author><name sortKey="Stasic, A" uniqKey="Stasic A">A Stasic</name></author><author><name sortKey="Grgurevic, Z" uniqKey="Grgurevic Z">Z Grgurevic</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hu, S" uniqKey="Hu S">S Hu</name></author><author><name sortKey="Kuo, Tt" uniqKey="Kuo T">TT Kuo</name></author><author><name sortKey="Hong, Hs" uniqKey="Hong H">HS Hong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kaya, Ti" uniqKey="Kaya T">TI Kaya</name></author><author><name sortKey="Kokturk, A" uniqKey="Kokturk A">A Kokturk</name></author><author><name sortKey="Tursen, U" uniqKey="Tursen U">U Tursen</name></author><author><name sortKey="Ikizoglu, G" uniqKey="Ikizoglu G">G Ikizoglu</name></author><author><name sortKey="Polat, A" uniqKey="Polat A">A Polat</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bannerot, H" uniqKey="Bannerot H">H Bannerot</name></author><author><name sortKey="Aubin, F" uniqKey="Aubin F">F Aubin</name></author><author><name sortKey="Tropet, Y" uniqKey="Tropet Y">Y Tropet</name></author><author><name sortKey="Najean, D" uniqKey="Najean D">D Najean</name></author><author><name sortKey="Blanc, D" uniqKey="Blanc D">D Blanc</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosenthal, G" uniqKey="Rosenthal G">G Rosenthal</name></author><author><name sortKey="Lifshitz, T" uniqKey="Lifshitz T">T Lifshitz</name></author><author><name sortKey="Monos, T" uniqKey="Monos T">T Monos</name></author><author><name sortKey="Kachco, L" uniqKey="Kachco L">L Kachco</name></author><author><name sortKey="Argov, S" uniqKey="Argov S">S Argov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shirani, Am" uniqKey="Shirani A">AM Shirani</name></author><author><name sortKey="Birang, R" uniqKey="Birang R">R Birang</name></author><author><name sortKey="Razavi, Sm" uniqKey="Razavi S">SM Razavi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Green, Cj" uniqKey="Green C">CJ Green</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="case-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Dent Res Dent Clin Dent Prospects</journal-id><journal-id journal-id-type="iso-abbrev">J Dent Res Dent Clin Dent Prospects</journal-id><journal-id journal-id-type="publisher-id">Journal of Dental Research, Dental Clinics, Dental Prospects</journal-id><journal-title-group><journal-title>Journal of Dental Research, Dental Clinics, Dental Prospects</journal-title></journal-title-group><issn pub-type="ppub">2008-210X</issn><issn pub-type="epub">2008-2118</issn><publisher><publisher-name>Tabriz University of Medical Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">23289062</article-id><article-id pub-id-type="pmc">3532738</article-id><article-id pub-id-type="doi">10.5681/joddd.2008.014</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Cryosurgery (N2O) Application to Remove Lip Lesions of Lipoid Proteinosis Syndrome: A Case Report</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Shirani</surname><given-names>Amir Mansour</given-names></name><xref ref-type="aff" rid="A01"><sup>1</sup></xref><xref rid="COR1" ref-type="corresp">*</xref></contrib></contrib-group><aff id="A01"><sup>1</sup>Assistant Professor, Department of Oral Medicine, Faculty of Dentistry, Isfahan University of Medical Sciences, Iran</aff><author-notes><corresp id="COR1"><label>*</label>Corresponding Author, <email>am_shirani@dnt.mui.ac.ir</email></corresp></author-notes><pub-date pub-type="ppub"><season>Spring</season><year>2008</year></pub-date><pub-date pub-type="epub"><day>15</day><month>8</month><year>2008</year></pub-date><volume>2</volume><issue>2</issue><fpage>68</fpage><lpage>70</lpage><history><date date-type="received"><day>12</day><month>1</month><year>2008</year></date><date date-type="accepted"><day>15</day><month>3</month><year>2008</year></date></history><permissions><copyright-year>2008</copyright-year></permissions><abstract><p>Lipoid proteinosis is a rare hereditary metabolic disorder transmitted as an autosomal recessive trait. It is characterized by the deposition of an amorphous hyaline-like material (glycoprotein) in the mucous membranes, skin and various internal organs. Cryosurgery (N<sub>2</sub>O) was applied to remove and reshape the lip lesions in a case of this rare syndrome.
The patient was a 24-year-old female. Cryosurgery (−63ºC N<sub>2</sub>O for one minute) was performed to re-shape some areas of the upper lip. The lips were softer and had better esthetics after treatment. The use of cryosurgery offers advantages over surgery in reshaping of the lip lesions in this syndrome, since suturing is not feasible in rigid mucosa of these patients.
</p></abstract><kwd-group><kwd>Cryosurgery</kwd><kwd>lipoid proteinosis syndrome</kwd><kwd>N<sub>2</sub>O</kwd></kwd-group></article-meta></front><body><sec id="s0"><title>Introduction</title><p>Lipoid proteinosis, also known as hyalinosis cutis et mucosae (OMIM 247100), was first described by Urbach and Wiethe in 1929.<sup><xref rid="R01" ref-type="bibr">1</xref></sup> Since then, over 250 cases of this autosomal recessive disorder have been described.<sup><xref rid="R02" ref-type="bibr">2</xref></sup> It is characterized by the deposition of an amorphous hyaline substance (glycoprotein) in the mucous membrane and skin.<sup><xref rid="R03" ref-type="bibr">3</xref></sup> Hoarseness and thickening of vocal cords are the most characteristic symptoms present from infancy or early childhood.<sup><xref rid="R03" ref-type="bibr">3</xref>,
<xref rid="R04" ref-type="bibr">4</xref></sup> Another classic and most easily recognizable sign is the beaded eyelid papules.<sup><xref rid="R05" ref-type="bibr">5</xref></sup> The other cutaneous changes may include waxy, yellow papules and nodules with generalized skin thickening.<sup><xref rid="R02" ref-type="bibr">2</xref></sup> The mucosa of the pharynx, tongue, soft palate, tonsils and lips is also infiltrated.<sup><xref rid="R06" ref-type="bibr">6</xref>,
<xref rid="R07" ref-type="bibr">7</xref></sup> Other features may include epilepsy and calcification in the temporal lobes or hippocampi.<sup><xref rid="R08" ref-type="bibr">8</xref></sup></p><p>Since suturing is difficult because of rigid mucosa in these patients, the use of cryosurgery seems to offer advantages for removing oral nodular lesions. Therefore, cryosurgery (N<sub>2</sub>O) was performed to remove and reshape the lip lesions in a case of this rare syndrome.
</p><fig-group id="Fg01" orientation="portrait" position="float"><caption><title>Figure 1. Lip and tongue involvement in the 24-year-old patient with lipoid proteinosis (a); eyelid papules (b) and skin lesions (c) in the same patient.
</title></caption><fig id="F01" orientation="portrait" position="anchor"><label>a</label><graphic xlink:href="joddd-2-68-g001"></graphic></fig><fig id="F02" orientation="portrait" position="anchor"><label>b</label><graphic xlink:href="joddd-2-68-g002"></graphic></fig><fig id="F03" orientation="portrait" position="anchor"><label>c</label><graphic xlink:href="joddd-2-68-g003"></graphic></fig></fig-group></sec><sec id="s1"><title>Case report</title><p>The patient was a 24-year-old female from Shahrekord, Central Iran, who sought medical care at the Department of Oral Medicine, Isfahan University of Medical Sciences in 2003. The patient was completely edentulous and showed the classic signs of lipoid proteinosis (<xref rid="Fg01" ref-type="fig">Figure 1</xref>). During oral examination, the oral mucosa was rigid and labial mucosa had become nodular and thickened. The patient’s tongue was rigid and severely restricted in movement.
</p><p>The patient had six sisters and one brother, and two of her sisters (25 and 11 years old) suffered from the same syndrome. Other members of her family showed no signs of this disease. The results of complete blood analysis and routine urinalysis were all within the normal limits. Lateral cephalometric radiography of the skull revealed calcifications in the suprasellar region. The biopsy of lip lesions was performed with a scalpel under local anesthesia and examined by a pathologist to confirm the diagnosis. Suturing after biopsy was difficult because the mucosa was rigid and the sutures cut into it.
</p><fig-group id="Fg02" orientation="portrait" position="float"><caption><title>Figure 2. The use of cryogun for reshaping the upper lip (a); the ice ball observation at the site of cryosurgery immediately after removing cryogen (b); lip appearance in one-year follow up (c).
</title></caption><fig id="F04" orientation="portrait" position="anchor"><label>a</label><graphic xlink:href="joddd-2-68-g004"></graphic></fig><fig id="F05" orientation="portrait" position="anchor"><label>b</label><graphic xlink:href="joddd-2-68-g005"></graphic></fig><fig id="F06" orientation="portrait" position="anchor"><label>c</label><graphic xlink:href="joddd-2-68-g006"></graphic></fig></fig-group><p>The patient suffered from some nodules on upper lip. After applying local anesthetic spray on the site, cryosurgery (N<sub>2</sub>O, C 502T, EMD Co; Tehran, Iran) was performed (−63ºC for one minute), as this treatment has been used for similar superficial lesions.<sup><xref rid="R09" ref-type="bibr">9</xref></sup> It was applied on a continuous area of the upper lip. The surgery was done in two sessions; half of the lip was involved in each (Figure <xref rid="F04" ref-type="fig">2a</xref>,<xref rid="F05" ref-type="fig">b</xref>). Ibuprofen 400 mg (qid) was prescribed for pain control.
</p><p>The superficial layers were fallen by day 3. After the operation, the patient had pain for about a week with a visual analogue scale of up to five. Healing was good after approximately one month. The upper lip was softer than before treatment.
</p><p>In one year follow up, no new nodules were formed; however, some fissures were created on her lip (<xref rid="F06" ref-type="fig">Figure 2c</xref>). After the treatments, the appearance and the emotional state of this young female had improved.
</p></sec><sec sec-type="discussion" id="s2"><title>Discussion</title><p>Lipoid proteinosis is a rare autosomal recessive disorder accompanied by hoarseness as well as infiltration and thickening of the skin and certain mucous membranes. Recently, lipoid proteinosis was mapped to 1q21 and pathogenetic loss-of-function mutations were identified in the extracellular matrix protein 1 (ECM1) gene.<sup><xref rid="R02" ref-type="bibr">2</xref>,
<xref rid="R04" ref-type="bibr">4</xref></sup> Some treatments for this disorder have already been reported. A case of lipoid proteinosis was successfully treated with dimethyl sulfoxide,<sup><xref rid="R10" ref-type="bibr">10</xref></sup> however, in three other cases, it showed no beneficial effect.<sup><xref rid="R11" ref-type="bibr">11</xref></sup> Retinoids have shown encouraging results in cutaneous lesions in previous studies.<sup><xref rid="R12" ref-type="bibr">12</xref>,
<xref rid="R13" ref-type="bibr">13</xref></sup>D-Penicillamine had a favorable effect in a patient with this syndrome.<sup><xref rid="R14" ref-type="bibr">14</xref></sup> Microlaryngoscopy and dissection of the vocal cords, dermabrasion, chemical skin peeling and blepharoplasty were performed in some cases.<sup><xref rid="R05" ref-type="bibr">5</xref>,
<xref rid="R01" ref-type="bibr">1</xref></sup> Lasers are used in many fields of medicine and dentistry. Carbon dioxide laser surgery of thickened vocal cords and beaded eyelid papules has proved to be helpful in some studies.<sup><xref rid="R02" ref-type="bibr">2</xref>,
<xref rid="R01" ref-type="bibr">1</xref></sup> Nd:YAG and Er:YAG lasers were applied to remove oral lesions in one case of this syndrome.<sup><xref rid="R01" ref-type="bibr">1</xref></sup></p><p>Cryosurgery is the use of very low temperatures to destroy tissue. Immediately following cryosurgery, tissues are virtually indistinguishable from the normal, but latent damage is produced which progresses to severe destruction of the tissue. It can be used for removing many oral lesions like benign or malignant tumors.<sup><xref rid="R01" ref-type="bibr">1</xref></sup> It is a safe, effective method of treatment for many benign soft tissue lesions in the oral cavity. As suturing was difficult in this patient and mucosa was rigid, the use of cryosurgery seemed to offer some advantages in removing oral lesions in this case. The firm tissues were removed without any bleeding and deformity of the lip. It seems that surgical methods like cryosurgery and laser<sup><xref rid="R01" ref-type="bibr">1</xref>,
<xref rid="R01" ref-type="bibr">1</xref></sup> have some advantages over conventional surgery for removing oral lesions of lipoid proteinosis syndrome as there is no bleeding and no need to suture, and it is more comfortable for the patient.
</p><p>The described approach is considered an early report of N<sub>2</sub>O cryosurgery being used in removal and reshaping of lip lesions of this rare syndrome. This treatment seemed to be better than the conventional surgery.
</p></sec></body><back><ref-list><title>References</title><ref id="R01"><label>1</label><element-citation publication-type="journal"><name><surname>Urbach</surname><given-names>E</given-names></name><name><surname>Wiethe</surname><given-names>C</given-names></name><article-title>Lipoidosis cutis et mucosae</article-title><source>Virchows Arch Path Anat</source><year>1929</year><volume>273</volume><fpage>258</fpage><lpage>319</lpage></element-citation></ref><ref id="R02"><label>2</label><element-citation publication-type="journal"><name><surname>Hamada</surname><given-names>T</given-names></name><article-title>Lipoid proteinosis</article-title><source>Clin Exp Dermatol</source><year>2002</year><volume>27</volume><fpage>624</fpage><lpage>9</lpage><pub-id pub-id-type="pmid">12472532</pub-id></element-citation></ref><ref id="R03"><label>3</label><element-citation publication-type="book"><name><surname>Laskaris</surname><given-names>G</given-names></name><source>Color Atlas of Oral Diseases</source><edition>3rd ed</edition><year>2003</year><publisher-loc>Stuttgart-New York</publisher-loc><publisher-name>Thieme</publisher-name><size units="page">292-293</size></element-citation></ref><ref id="R04"><label>4</label><element-citation publication-type="journal"><name><surname>Hamada</surname><given-names>T</given-names></name><name><surname>Wessagowit</surname><given-names>V</given-names></name><name><surname>South</surname><given-names>AP</given-names></name><name><surname>Ashton</surname><given-names>GH</given-names></name><name><surname>Chan</surname><given-names>I</given-names></name><name><surname>Oyama</surname><given-names>N</given-names></name><etal></etal><article-title>Extracellular matrix protein 1 gene (ECM1) mutations in lipoid proteinosis and genotype-phenotype correlation</article-title><source>J Invest Dermatol</source><year>2003</year><volume>120</volume><fpage>345</fpage><lpage>50</lpage><pub-id pub-id-type="pmid">12603844</pub-id></element-citation></ref><ref id="R05"><label>5</label><element-citation publication-type="journal"><name><surname>Bozdağ</surname><given-names>KE</given-names></name><name><surname>Gül</surname><given-names>Y</given-names></name><name><surname>Karaman</surname><given-names>A</given-names></name><article-title>Lipoid proteinosis</article-title><source>Int J Dermatol</source><year>2000</year><volume>39</volume><fpage>203</fpage><lpage>4</lpage><pub-id pub-id-type="pmid">10759961</pub-id></element-citation></ref><ref id="R06"><label>6</label><element-citation publication-type="journal"><name><surname>Disdier</surname><given-names>P</given-names></name><name><surname>Harlé</surname><given-names>JR</given-names></name><name><surname>Andrac</surname><given-names>L</given-names></name><name><surname>Swiader</surname><given-names>L</given-names></name><name><surname>Weiller</surname><given-names>PJ</given-names></name><article-title>Specific xerostomia during Urbach-Wiethe disease</article-title><source>Dermatology</source><year>1994</year><volume>188</volume><fpage>50</fpage><lpage>1</lpage><pub-id pub-id-type="pmid">8305758</pub-id></element-citation></ref><ref id="R07"><label>7</label><element-citation publication-type="journal"><name><surname>Bazopoulou-Kyrkanidou</surname><given-names>E</given-names></name><name><surname>Tosios</surname><given-names>KI</given-names></name><name><surname>Zabelis</surname><given-names>G</given-names></name><name><surname>Charalampopoulou</surname><given-names>S</given-names></name><name><surname>Papanicolaou</surname><given-names>SI</given-names></name><article-title>Hyalinosis cutis et mucosae: gingival involvement</article-title><source>J Oral Pathol Med</source><year>1998</year><volume>27</volume><fpage>233</fpage><lpage>7</lpage><pub-id pub-id-type="pmid">9682988</pub-id></element-citation></ref><ref id="R08"><label>8</label><element-citation publication-type="journal"><name><surname>Friedman</surname><given-names>L</given-names></name><name><surname>Mathews</surname><given-names>RD</given-names></name><name><surname>Swanepoel</surname><given-names>PD</given-names></name><article-title>Radiographic and computed tomographic findings in lipoid proteinosisA case report</article-title><source>S Afr Med J</source><year>1984</year><volume>65</volume><fpage>734</fpage><lpage>5</lpage><pub-id pub-id-type="pmid">6719306</pub-id></element-citation></ref><ref id="R09"><label>9</label><element-citation publication-type="book"><name><surname>Poswillo</surname><given-names>D</given-names></name><source>Cryosurgery of benign oral and orofacial lesions. In: Bradley PF, ed. Cryosurgery of the Maxillofacial Region: General Principles and Clinical Application to Benign Lesions</source><year>1986</year><publisher-loc>Boca Raton</publisher-loc><publisher-name>CRC Press</publisher-name><size units="page">153-175</size></element-citation></ref><ref id="R10"><label>10</label><element-citation publication-type="journal"><name><surname>Wong</surname><given-names>CK</given-names></name><name><surname>Lin</surname><given-names>CS</given-names></name><article-title>Remarkable response of lipoid proteinosis to oral dimethyl sulphoxide</article-title><source>Br J Dermatol</source><year>1988</year><volume>119</volume><fpage>541</fpage><lpage>544</lpage><pub-id pub-id-type="pmid">3191019</pub-id></element-citation></ref><ref id="R11"><label>11</label><element-citation publication-type="journal"><name><surname>Ozkaya-Bayazit</surname><given-names>E</given-names></name><name><surname>Ozarmağan</surname><given-names>G</given-names></name><name><surname>Baykal</surname><given-names>C</given-names></name><name><surname>Uluğ</surname><given-names>T</given-names></name><article-title>[Oral DMSO therapy in 3 patients with lipoidproteinosisResults of long-term therapy]</article-title><source>Hautarzt</source><year>1997</year><volume>48</volume><fpage>477</fpage><lpage>81</lpage><pub-id pub-id-type="pmid">9333627</pub-id></element-citation></ref><ref id="R12"><label>12</label><element-citation publication-type="journal"><name><surname>Gruber</surname><given-names>F</given-names></name><name><surname>Manestar</surname><given-names>D</given-names></name><name><surname>Stasic</surname><given-names>A</given-names></name><name><surname>Grgurevic</surname><given-names>Z</given-names></name><article-title>Treatment of lipoid proteinosis with etretinate</article-title><source>Acta Derm Venereol</source><year>1996</year><volume>76</volume><fpage>154</fpage><lpage>5</lpage><pub-id pub-id-type="pmid">8740275</pub-id></element-citation></ref><ref id="R13"><label>13</label><element-citation publication-type="journal"><name><surname>Hu</surname><given-names>S</given-names></name><name><surname>Kuo</surname><given-names>TT</given-names></name><name><surname>Hong</surname><given-names>HS</given-names></name><article-title>Lipoid proteinosis: report of a possible localized form on both hands and wrists</article-title><source>Int J Dermatol</source><year>2005</year><volume>44</volume><fpage>408</fpage><lpage>10</lpage><pub-id pub-id-type="pmid">15869539</pub-id></element-citation></ref><ref id="R14"><label>14</label><element-citation publication-type="journal"><name><surname>Kaya</surname><given-names>TI</given-names></name><name><surname>Kokturk</surname><given-names>A</given-names></name><name><surname>Tursen</surname><given-names>U</given-names></name><name><surname>Ikizoglu</surname><given-names>G</given-names></name><name><surname>Polat</surname><given-names>A</given-names></name><article-title>D-penicillamine treatment for lipoid proteinosis</article-title><source>Pediatr Dermatol</source><year>2002</year><volume>19</volume><fpage>359</fpage><lpage>62</lpage><pub-id pub-id-type="pmid">12220287</pub-id></element-citation></ref><ref id="R15"><label>15</label><element-citation publication-type="journal"><name><surname>Bannerot</surname><given-names>H</given-names></name><name><surname>Aubin</surname><given-names>F</given-names></name><name><surname>Tropet</surname><given-names>Y</given-names></name><name><surname>Najean</surname><given-names>D</given-names></name><name><surname>Blanc</surname><given-names>D</given-names></name><article-title>[Lipoid proteinosis: importance of dermabrasionApropos of a case]</article-title><source>Ann Chir Plast Esthet</source><year>1998</year><volume>43</volume><fpage>78</fpage><lpage>81</lpage><pub-id pub-id-type="pmid">9768096</pub-id></element-citation></ref><ref id="R16"><label>16</label><element-citation publication-type="journal"><name><surname>Rosenthal</surname><given-names>G</given-names></name><name><surname>Lifshitz</surname><given-names>T</given-names></name><name><surname>Monos</surname><given-names>T</given-names></name><name><surname>Kachco</surname><given-names>L</given-names></name><name><surname>Argov</surname><given-names>S</given-names></name><article-title>Carbon dioxide laser treatment for lipoid proteinosis (Urbach-Wiethe syndrome) involving the eyelids</article-title><source>Br J Ophthalmol</source><year>1997</year><volume>81</volume><fpage>253</fpage><pub-id pub-id-type="pmid">9135394</pub-id></element-citation></ref><ref id="R17"><label>17</label><element-citation publication-type="journal"><name><surname>Shirani</surname><given-names>AM</given-names></name><name><surname>Birang</surname><given-names>R</given-names></name><name><surname>Razavi</surname><given-names>SM</given-names></name><article-title>Nd:YAG and Er:YAG Laser Application to Remove Oral Lesions of Lipoid Proteinosis</article-title><source>J Oral Laser Appl</source><year>2006</year><volume>6</volume><fpage>201</fpage><lpage>4</lpage></element-citation></ref><ref id="R18"><label>18</label><element-citation publication-type="book"><name><surname>Green</surname><given-names>CJ</given-names></name><source>The biophysical responses of tissues to extreme temperature changes. In: Bradley PF, ed. Cryosurgery of the Maxillofacial Region: General Principles and Clinical Application to Benign Lesions</source><year>1986</year><publisher-loc>Boca Raton</publisher-loc><publisher-name>CRC Press</publisher-name><size units="page">17-34</size></element-citation></ref></ref-list></back></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001D97 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 001D97 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Pmc
|étape= Corpus
|type= RBID
|clé= PMC:3532738
|texte= Cryosurgery (N2O) Application to Remove Lip Lesions of Lipoid Proteinosis Syndrome: A Case Report
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/RBID.i -Sk "pubmed:23289062" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a EdenteV2
| This area was generated with Dilib version V0.6.32. |  |