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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">An unusual case of atrophic mandible fracture in a patient with osteogenesis imperfecta and on oral bisphosphonate therapy: Case report</title><author><name sortKey="Al Osaimi, Abdulrahman" sort="Al Osaimi, Abdulrahman" uniqKey="Al Osaimi A" first="Abdulrahman" last="Al-Osaimi">Abdulrahman Al-Osaimi</name><affiliation><nlm:aff id="af005">Department of Oral and Maxillofacial Surgery, King Saud Medical Complex, Riyadh, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Samman, Mahmood" sort="Samman, Mahmood" uniqKey="Samman M" first="Mahmood" last="Samman">Mahmood Samman</name><affiliation><nlm:aff id="af010">Department of Oral and Maxillofacial Surgery, King Fahd Hospital, Al Madinah, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Al Shakhs, Mohammad" sort="Al Shakhs, Mohammad" uniqKey="Al Shakhs M" first="Mohammad" last="Al-Shakhs">Mohammad Al-Shakhs</name><affiliation><nlm:aff id="af005">Department of Oral and Maxillofacial Surgery, King Saud Medical Complex, Riyadh, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Al Suhaim, Faisal" sort="Al Suhaim, Faisal" uniqKey="Al Suhaim F" first="Faisal" last="Al-Suhaim">Faisal Al-Suhaim</name><affiliation><nlm:aff id="af005">Department of Oral and Maxillofacial Surgery, King Saud Medical Complex, Riyadh, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Ramalingam, Sundar" sort="Ramalingam, Sundar" uniqKey="Ramalingam S" first="Sundar" last="Ramalingam">Sundar Ramalingam</name><affiliation><nlm:aff id="af015">Department of Oral and Maxillofacial Surgery, College of Dentistry, King Saud University, Riyadh, Saudi Arabia</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25408599</idno><idno type="pmc">4229676</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229676</idno><idno type="RBID">PMC:4229676</idno><idno type="doi">10.1016/j.sdentj.2013.12.008</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">001954</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001954</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">An unusual case of atrophic mandible fracture in a patient with osteogenesis imperfecta and on oral bisphosphonate therapy: Case report</title><author><name sortKey="Al Osaimi, Abdulrahman" sort="Al Osaimi, Abdulrahman" uniqKey="Al Osaimi A" first="Abdulrahman" last="Al-Osaimi">Abdulrahman Al-Osaimi</name><affiliation><nlm:aff id="af005">Department of Oral and Maxillofacial Surgery, King Saud Medical Complex, Riyadh, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Samman, Mahmood" sort="Samman, Mahmood" uniqKey="Samman M" first="Mahmood" last="Samman">Mahmood Samman</name><affiliation><nlm:aff id="af010">Department of Oral and Maxillofacial Surgery, King Fahd Hospital, Al Madinah, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Al Shakhs, Mohammad" sort="Al Shakhs, Mohammad" uniqKey="Al Shakhs M" first="Mohammad" last="Al-Shakhs">Mohammad Al-Shakhs</name><affiliation><nlm:aff id="af005">Department of Oral and Maxillofacial Surgery, King Saud Medical Complex, Riyadh, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Al Suhaim, Faisal" sort="Al Suhaim, Faisal" uniqKey="Al Suhaim F" first="Faisal" last="Al-Suhaim">Faisal Al-Suhaim</name><affiliation><nlm:aff id="af005">Department of Oral and Maxillofacial Surgery, King Saud Medical Complex, Riyadh, Saudi Arabia</nlm:aff></affiliation></author><author><name sortKey="Ramalingam, Sundar" sort="Ramalingam, Sundar" uniqKey="Ramalingam S" first="Sundar" last="Ramalingam">Sundar Ramalingam</name><affiliation><nlm:aff id="af015">Department of Oral and Maxillofacial Surgery, College of Dentistry, King Saud University, Riyadh, Saudi Arabia</nlm:aff></affiliation></author></analytic><series><title level="j">The Saudi Dental Journal</title><idno type="ISSN">1013-9052</idno><idno type="eISSN">1658-3558</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Fractures of severely atrophic (height < 10 mm) edentulous mandibles are infrequent and challenging to manage. Factors such as sclerotic bone and decreased vascularity combined with systemic diseases complicate the management of such fractures. Osteogenesis imperfecta (OI) is a heterogeneous group of inherited disorders of type I collagen metabolism. Patients with OI characteristically present with histories of long bone fractures, deformities, blue sclerae, and opalescent dentin. However, fractures of the facial skeleton are rare. Bisphosphonate therapy has been proven to effectively reduce the fracture risk in patients with OI. The purpose of this clinical report is to present an unusual case of spontaneous fracture of the atrophic mandible in a patient with OI. Despite open reduction and internal fixation (ORIF) with miniplate osteosynthesis, the patient developed a second fracture at a screw placement site distal to the first fracture. The patient was successfully treated with ORIF using locking reconstruction plates fixed in the symphyseal and angle regions. Bone healing following ORIF was normal, and no clinical sign of osteonecrosis as a result of bisphosphonate therapy was observed. Patients with OI can present with spontaneous fractures of already weakened mandibles. Although such fractures can be managed with care using established protocols, further research is required to examine the effects of concomitant medication, such as bisphosphonates.</p></div></front></TEI><pmc article-type="brief-report"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Saudi Dent J</journal-id><journal-id journal-id-type="iso-abbrev">Saudi Dent J</journal-id><journal-title-group><journal-title>The Saudi Dental Journal</journal-title></journal-title-group><issn pub-type="ppub">1013-9052</issn><issn pub-type="epub">1658-3558</issn><publisher><publisher-name>Elsevier</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25408599</article-id><article-id pub-id-type="pmc">4229676</article-id><article-id pub-id-type="publisher-id">S1013-9052(14)00015-7</article-id><article-id pub-id-type="doi">10.1016/j.sdentj.2013.12.008</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>An unusual case of atrophic mandible fracture in a patient with osteogenesis imperfecta and on oral bisphosphonate therapy: Case report</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Al-Osaimi</surname><given-names>Abdulrahman</given-names></name><xref rid="af005" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Samman</surname><given-names>Mahmood</given-names></name><xref rid="af010" ref-type="aff">b</xref></contrib><contrib contrib-type="author"><name><surname>Al-Shakhs</surname><given-names>Mohammad</given-names></name><xref rid="af005" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Al-Suhaim</surname><given-names>Faisal</given-names></name><xref rid="af005" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Ramalingam</surname><given-names>Sundar</given-names></name><email>sundar.ksu@gmail.com</email><xref rid="af015" ref-type="aff">c</xref><xref rid="cor1" ref-type="corresp">⁎</xref></contrib></contrib-group><aff id="af005"><label>a</label>Department of Oral and Maxillofacial Surgery, King Saud Medical Complex, Riyadh, Saudi Arabia</aff><aff id="af010"><label>b</label>Department of Oral and Maxillofacial Surgery, King Fahd Hospital, Al Madinah, Saudi Arabia</aff><aff id="af015"><label>c</label>Department of Oral and Maxillofacial Surgery, College of Dentistry, King Saud University, Riyadh, Saudi Arabia</aff><author-notes><corresp id="cor1"><label>⁎</label>Corresponding author. Address: Department of Oral and Maxillofacial Surgery, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia. Tel.: +966 532092386. <email>sundar.ksu@gmail.com</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>12</day><month>3</month><year>2014</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="epub"><day>12</day><month>3</month><year>2014</year></pub-date><pub-date pub-type="ppub"><month>4</month><year>2014</year></pub-date><volume>26</volume><issue>2</issue><fpage>68</fpage><lpage>73</lpage><history><date date-type="received"><day>27</day><month>11</month><year>2013</year></date><date date-type="rev-recd"><day>14</day><month>12</month><year>2013</year></date><date date-type="accepted"><day>24</day><month>12</month><year>2013</year></date></history><permissions><copyright-statement>© 2014 King Saud University. Production and Hosting by Elsevier B.V. All rights reserved.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder>King Saud University</copyright-holder></permissions><abstract><p>Fractures of severely atrophic (height < 10 mm) edentulous mandibles are infrequent and challenging to manage. Factors such as sclerotic bone and decreased vascularity combined with systemic diseases complicate the management of such fractures. Osteogenesis imperfecta (OI) is a heterogeneous group of inherited disorders of type I collagen metabolism. Patients with OI characteristically present with histories of long bone fractures, deformities, blue sclerae, and opalescent dentin. However, fractures of the facial skeleton are rare. Bisphosphonate therapy has been proven to effectively reduce the fracture risk in patients with OI. The purpose of this clinical report is to present an unusual case of spontaneous fracture of the atrophic mandible in a patient with OI. Despite open reduction and internal fixation (ORIF) with miniplate osteosynthesis, the patient developed a second fracture at a screw placement site distal to the first fracture. The patient was successfully treated with ORIF using locking reconstruction plates fixed in the symphyseal and angle regions. Bone healing following ORIF was normal, and no clinical sign of osteonecrosis as a result of bisphosphonate therapy was observed. Patients with OI can present with spontaneous fractures of already weakened mandibles. Although such fractures can be managed with care using established protocols, further research is required to examine the effects of concomitant medication, such as bisphosphonates.</p></abstract><kwd-group><title>Keywords</title><kwd>Atrophic mandible</kwd><kwd>Mandible fracture</kwd><kwd>Osteogenesis imperfecta</kwd><kwd>Bisphosphonates</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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