T cell proliferative responses to molecular fractions of periodontopathic bacteria.
Identifieur interne : 001504 ( Pmc/Corpus ); précédent : 001503; suivant : 001505T cell proliferative responses to molecular fractions of periodontopathic bacteria.
Auteurs : L. Ivanyi ; H N Newman ; P D MarshSource :
- Clinical and Experimental Immunology [ 0009-9104 ] ; 1991.
Abstract
Soluble antigenic preparations of Veillonella parvula and Bacteroides gingivalis were separated by SDS-PAGE and used after electroblotting and solubilization for in vitro lymphocyte stimulation in 13 patients with severe periodontitis and 12 controls. The cellular responses of controls and patients to V. parvula antigens were represented by four main proliferation-inducing fractions with 74-66, 52-46, 22-19 and 12 kD mol. wt. These fractions induced slightly enhanced DNA synthesis in lymphocytes from eight patients who failed to respond to whole antigenic extract. Lymphocyte samples from Veillonella whole extract unresponsive patients were also examined for in vitro proliferation by B. gingivalis fractions. Almost all stimulatory activities could be classified into five regions of 84-74, 35-31, 28-25, 17-15 and 12 kD.
Url:
PubMed: 1988218
PubMed Central: 1535464
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PMC:1535464Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">T cell proliferative responses to molecular fractions of periodontopathic bacteria.</title><author><name sortKey="Ivanyi, L" sort="Ivanyi, L" uniqKey="Ivanyi L" first="L" last="Ivanyi">L. Ivanyi</name></author><author><name sortKey="Newman, H N" sort="Newman, H N" uniqKey="Newman H" first="H N" last="Newman">H N Newman</name></author><author><name sortKey="Marsh, P D" sort="Marsh, P D" uniqKey="Marsh P" first="P D" last="Marsh">P D Marsh</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">1988218</idno><idno type="pmc">1535464</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1535464</idno><idno type="RBID">PMC:1535464</idno><date when="1991">1991</date><idno type="wicri:Area/Pmc/Corpus">001504</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001504</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">T cell proliferative responses to molecular fractions of periodontopathic bacteria.</title><author><name sortKey="Ivanyi, L" sort="Ivanyi, L" uniqKey="Ivanyi L" first="L" last="Ivanyi">L. Ivanyi</name></author><author><name sortKey="Newman, H N" sort="Newman, H N" uniqKey="Newman H" first="H N" last="Newman">H N Newman</name></author><author><name sortKey="Marsh, P D" sort="Marsh, P D" uniqKey="Marsh P" first="P D" last="Marsh">P D Marsh</name></author></analytic><series><title level="j">Clinical and Experimental Immunology</title><idno type="ISSN">0009-9104</idno><idno type="eISSN">1365-2249</idno><imprint><date when="1991">1991</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Soluble antigenic preparations of Veillonella parvula and Bacteroides gingivalis were separated by SDS-PAGE and used after electroblotting and solubilization for in vitro lymphocyte stimulation in 13 patients with severe periodontitis and 12 controls. The cellular responses of controls and patients to V. parvula antigens were represented by four main proliferation-inducing fractions with 74-66, 52-46, 22-19 and 12 kD mol. wt. These fractions induced slightly enhanced DNA synthesis in lymphocytes from eight patients who failed to respond to whole antigenic extract. Lymphocyte samples from Veillonella whole extract unresponsive patients were also examined for in vitro proliferation by B. gingivalis fractions. Almost all stimulatory activities could be classified into five regions of 84-74, 35-31, 28-25, 17-15 and 12 kD.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Exp Immunol</journal-id><journal-title>Clinical and Experimental Immunology</journal-title><issn pub-type="ppub">0009-9104</issn><issn pub-type="epub">1365-2249</issn></journal-meta><article-meta><article-id pub-id-type="pmid">1988218</article-id><article-id pub-id-type="pmc">1535464</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>T cell proliferative responses to molecular fractions of periodontopathic bacteria.</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ivanyi</surname><given-names>L</given-names></name></contrib><contrib contrib-type="author"><name><surname>Newman</surname><given-names>H N</given-names></name></contrib><contrib contrib-type="author"><name><surname>Marsh</surname><given-names>P D</given-names></name></contrib></contrib-group><aff>Department of Clinical Pathology and Immunology, Institute of Dental Surgery, London, England, UK.</aff><pub-date pub-type="ppub"><month>1</month><year>1991</year></pub-date><volume>83</volume><issue>1</issue><fpage>108</fpage><lpage>111</lpage><abstract><p>Soluble antigenic preparations of Veillonella parvula and Bacteroides gingivalis were separated by SDS-PAGE and used after electroblotting and solubilization for in vitro lymphocyte stimulation in 13 patients with severe periodontitis and 12 controls. The cellular responses of controls and patients to V. parvula antigens were represented by four main proliferation-inducing fractions with 74-66, 52-46, 22-19 and 12 kD mol. wt. These fractions induced slightly enhanced DNA synthesis in lymphocytes from eight patients who failed to respond to whole antigenic extract. Lymphocyte samples from Veillonella whole extract unresponsive patients were also examined for in vitro proliferation by B. gingivalis fractions. Almost all stimulatory activities could be classified into five regions of 84-74, 35-31, 28-25, 17-15 and 12 kD.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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