Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Immunoconglutinins and C3 in human saliva.</title><author><name sortKey="Williams, B D" sort="Williams, B D" uniqKey="Williams B" first="B D" last="Williams">B D Williams</name></author><author><name sortKey="Challacombe, S J" sort="Challacombe, S J" uniqKey="Challacombe S" first="S J" last="Challacombe">S J Challacombe</name></author><author><name sortKey="Slaney, J M" sort="Slaney, J M" uniqKey="Slaney J" first="J M" last="Slaney">J M Slaney</name></author><author><name sortKey="Lachmann, P J" sort="Lachmann, P J" uniqKey="Lachmann P" first="P J" last="Lachmann">P J Lachmann</name></author><author><name sortKey="Lehner, T" sort="Lehner, T" uniqKey="Lehner T" first="T" last="Lehner">T. Lehner</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">1239346</idno><idno type="pmc">1538149</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538149</idno><idno type="RBID">PMC:1538149</idno><date when="1975">1975</date><idno type="wicri:Area/Pmc/Corpus">001503</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001503</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Immunoconglutinins and C3 in human saliva.</title><author><name sortKey="Williams, B D" sort="Williams, B D" uniqKey="Williams B" first="B D" last="Williams">B D Williams</name></author><author><name sortKey="Challacombe, S J" sort="Challacombe, S J" uniqKey="Challacombe S" first="S J" last="Challacombe">S J Challacombe</name></author><author><name sortKey="Slaney, J M" sort="Slaney, J M" uniqKey="Slaney J" first="J M" last="Slaney">J M Slaney</name></author><author><name sortKey="Lachmann, P J" sort="Lachmann, P J" uniqKey="Lachmann P" first="P J" last="Lachmann">P J Lachmann</name></author><author><name sortKey="Lehner, T" sort="Lehner, T" uniqKey="Lehner T" first="T" last="Lehner">T. Lehner</name></author></analytic><series><title level="j">Clinical and Experimental Immunology</title><idno type="ISSN">0009-9104</idno><idno type="eISSN">1365-2249</idno><imprint><date when="1975">1975</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>High titres of immunoconglutinin activity (antibody to bound complement components) have been found in the parotid, sublingual and submandibular saliva of most healthy subjects. The immunoconglutinin (IK) titre in mixed saliva was substantially lower than in the other samples of saliva. C3 was detectable in only three of 164 samples of parotid, submandibular and sublingual saliva but was present in forty-seven of 117 mixed saliva samples. It is suggested that crevicular fluid is the major source of C3 in mixed saliva. A negative correlation was found in mixed saliva between the C3 concentration and the IK titre, and this suggested that C3 was the inhibitor of IK in mixed saliva. Binding of C3 to IK has been demonstrated in mixed saliva by using highly purified salivary IK and C3. Purified C3, C3i, C3c and C3d inhibited the activity of purified IK. It is suggested that salivary IK represents the secretion of a B-lymphocyte population which has evaded the mechanism responsible for inducing B-cell tolerance to autologous serum proteins. The reason for its persistence in the salivary glands, however, is not known at present.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Exp Immunol</journal-id><journal-title>Clinical and Experimental Immunology</journal-title><issn pub-type="ppub">0009-9104</issn><issn pub-type="epub">1365-2249</issn></journal-meta><article-meta><article-id pub-id-type="pmid">1239346</article-id><article-id pub-id-type="pmc">1538149</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Immunoconglutinins and C3 in human saliva.</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Williams</surname><given-names>B D</given-names></name></contrib><contrib contrib-type="author"><name><surname>Challacombe</surname><given-names>S J</given-names></name></contrib><contrib contrib-type="author"><name><surname>Slaney</surname><given-names>J M</given-names></name></contrib><contrib contrib-type="author"><name><surname>Lachmann</surname><given-names>P J</given-names></name></contrib><contrib contrib-type="author"><name><surname>Lehner</surname><given-names>T</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><month>3</month><year>1975</year></pub-date><volume>19</volume><issue>3</issue><fpage>423</fpage><lpage>423</lpage><abstract><p>High titres of immunoconglutinin activity (antibody to bound complement components) have been found in the parotid, sublingual and submandibular saliva of most healthy subjects. The immunoconglutinin (IK) titre in mixed saliva was substantially lower than in the other samples of saliva. C3 was detectable in only three of 164 samples of parotid, submandibular and sublingual saliva but was present in forty-seven of 117 mixed saliva samples. It is suggested that crevicular fluid is the major source of C3 in mixed saliva. A negative correlation was found in mixed saliva between the C3 concentration and the IK titre, and this suggested that C3 was the inhibitor of IK in mixed saliva. Binding of C3 to IK has been demonstrated in mixed saliva by using highly purified salivary IK and C3. Purified C3, C3i, C3c and C3d inhibited the activity of purified IK. It is suggested that salivary IK represents the secretion of a B-lymphocyte population which has evaded the mechanism responsible for inducing B-cell tolerance to autologous serum proteins. The reason for its persistence in the salivary glands, however, is not known at present.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001503 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 001503 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.32. |  |