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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">What is known about the influence of dentine hypersensitivity on oral health-related quality of life?</title><author><name sortKey="Bekes, Katrin" sort="Bekes, Katrin" uniqKey="Bekes K" first="Katrin" last="Bekes">Katrin Bekes</name><affiliation><nlm:aff id="Aff1">Department of Operative Dentistry and Periodontology, Department of Pediatric Dentistry, Martin-Luther-University Halle-Wittenberg, University School of Dental Medicine, Harz 42a, 06108 Halle, Germany</nlm:aff></affiliation></author><author><name sortKey="Hirsch, Christian" sort="Hirsch, Christian" uniqKey="Hirsch C" first="Christian" last="Hirsch">Christian Hirsch</name><affiliation><nlm:aff id="Aff2">Department of Pediatric Dentistry, University of Leipzig, Liebigstraße 10 – 14, House 1, 04103 Leipzig, Germany</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22290063</idno><idno type="pmc">3585945</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585945</idno><idno type="RBID">PMC:3585945</idno><idno type="doi">10.1007/s00784-012-0888-9</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">000E28</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000E28</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">What is known about the influence of dentine hypersensitivity on oral health-related quality of life?</title><author><name sortKey="Bekes, Katrin" sort="Bekes, Katrin" uniqKey="Bekes K" first="Katrin" last="Bekes">Katrin Bekes</name><affiliation><nlm:aff id="Aff1">Department of Operative Dentistry and Periodontology, Department of Pediatric Dentistry, Martin-Luther-University Halle-Wittenberg, University School of Dental Medicine, Harz 42a, 06108 Halle, Germany</nlm:aff></affiliation></author><author><name sortKey="Hirsch, Christian" sort="Hirsch, Christian" uniqKey="Hirsch C" first="Christian" last="Hirsch">Christian Hirsch</name><affiliation><nlm:aff id="Aff2">Department of Pediatric Dentistry, University of Leipzig, Liebigstraße 10 – 14, House 1, 04103 Leipzig, Germany</nlm:aff></affiliation></author></analytic><series><title level="j">Clinical Oral Investigations</title><idno type="ISSN">1432-6981</idno><idno type="eISSN">1436-3771</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objectives</title><p>Oral health-related quality of life is a relatively new but rapidly growing concept in dentistry. It is an aspect of dental health addressing the patient’s perception of whether his/her current oral health status has an impact upon his/her actual quality of life. Dentine hypersensitivity (DHS), which is a common condition of transient tooth pain associated with a variety of exogenous stimuli, may disturb the patient during eating, drinking, toothbrushing and sometimes even breathing. The resulting restrictions on everyday activities can have an important effect on the patient’s quality of life. The aims of this paper were to consider the concept of oral health-related quality of life and to review and discuss the literature on oral health-related quality of life and DHS.</p></sec><sec><title>Material and methods</title><p>A PubMed literature research was conducted using the terms (“dentin sensitivity” [MeSH Terms] OR (“dentin” [All Fields] AND “sensitivity” [All Fields]) OR “dentin sensitivity” [All Fields]) AND ((“oral health” [MeSH Terms] OR (“oral” [All Fields] AND “health” [All Fields]) OR “oral health” [All Fields]) AND related [All Fields] AND (“quality of life” [MeSH Terms] OR (“quality” [All Fields] AND “life” [All Fields]) OR “quality of life” [All Fields])). Furthermore, a manual search was carried out. Any relevant work published presenting pertinent information about the described issue was considered for inclusion in the review.</p></sec><sec><title>Results</title><p>The combination of the search terms resulted in a list of only three titles. The few published studies convincingly demonstrated that oral health-related quality of life is negatively affected in patients suffering from DHS.</p></sec><sec><title>Conclusions</title><p>Patients with sensitive teeth report substantial oral health-related quality of life (OHRQoL) impairment. Nevertheless, knowledge about the influence of DHS on oral health-related quality of life is incomplete and, therefore, needs further research.</p></sec><sec><title>Clinical relevance</title><p>Oral diseases can lead to physical, psychological and social disability. This paper shows that DHS can have a negative impact on the patients’ OHRQoL.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Slade, Gd" uniqKey="Slade G">GD Slade</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Allen, Pf" uniqKey="Allen P">PF Allen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Inglehart, M" uniqKey="Inglehart M">M Inglehart</name></author><author><name sortKey="Bagramian, Ra" uniqKey="Bagramian R">RA Bagramian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Shamrany, M" uniqKey="Al Shamrany M">M Al Shamrany</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Loe, H" uniqKey="Loe H">H Loe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Russell, Al" uniqKey="Russell A">AL 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sortKey="Gotfredsen, K" uniqKey="Gotfredsen K">K Gotfredsen</name></author><author><name sortKey="Trab Damsgaard, M" uniqKey="Trab Damsgaard M">M Trab Damsgaard</name></author><author><name sortKey="Hede, B" uniqKey="Hede B">B Hede</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mulligan, R" uniqKey="Mulligan R">R Mulligan</name></author><author><name sortKey="Seirawan, H" uniqKey="Seirawan H">H Seirawan</name></author><author><name sortKey="Alves, Me" uniqKey="Alves M">ME Alves</name></author><author><name sortKey="Navazesh, M" uniqKey="Navazesh M">M Navazesh</name></author><author><name sortKey="Phelan, Ja" uniqKey="Phelan J">JA Phelan</name></author><author><name sortKey="Greenspan, D" uniqKey="Greenspan D">D Greenspan</name></author><author><name sortKey="Greenspan, Js" uniqKey="Greenspan J">JS Greenspan</name></author><author><name sortKey="Mack, Wj" uniqKey="Mack W">WJ 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Locker</name></author><author><name sortKey="Awad, Ma" uniqKey="Awad M">MA Awad</name></author><author><name sortKey="Lund, Jp" uniqKey="Lund J">JP Lund</name></author><author><name sortKey="Feine, Js" uniqKey="Feine J">JS Feine</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hegarty, Am" uniqKey="Hegarty A">AM Hegarty</name></author><author><name sortKey="Hodgson, Ta" uniqKey="Hodgson T">TA Hodgson</name></author><author><name sortKey="Lewsey, Jd" uniqKey="Lewsey J">JD Lewsey</name></author><author><name sortKey="Porter, Sr" uniqKey="Porter S">SR Porter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Addy, M" uniqKey="Addy M">M Addy</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Lier, Bb" uniqKey="Lier B">BB Lier</name></author><author><name sortKey="Rosing, Ck" uniqKey="Rosing C">CK Rosing</name></author><author><name sortKey="Aass, Am" uniqKey="Aass A">AM Aass</name></author><author><name sortKey="Gjermo, P" uniqKey="Gjermo P">P Gjermo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Orchardson, R" uniqKey="Orchardson R">R Orchardson</name></author><author><name sortKey="Collins, Wj" uniqKey="Collins W">WJ Collins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chabanski, Mb" uniqKey="Chabanski M">MB Chabanski</name></author><author><name sortKey="Gillam, Dg" uniqKey="Gillam D">DG Gillam</name></author><author><name sortKey="Bulman, Js" uniqKey="Bulman J">JS Bulman</name></author><author><name sortKey="Newman, Hn" uniqKey="Newman H">HN Newman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="John, Mt" uniqKey="John M">MT John</name></author><author><name sortKey="Leresche, L" uniqKey="Leresche L">L LeResche</name></author><author><name sortKey="Koepsell, Td" uniqKey="Koepsell T">TD Koepsell</name></author><author><name 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B">BJ Gibson</name></author><author><name sortKey="Locker, D" uniqKey="Locker D">D Locker</name></author><author><name sortKey="Sufi, F" uniqKey="Sufi F">F Sufi</name></author><author><name sortKey="Barlow, Ap" uniqKey="Barlow A">AP Barlow</name></author><author><name sortKey="Robinson, Pg" uniqKey="Robinson P">PG Robinson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bekes, K" uniqKey="Bekes K">K Bekes</name></author><author><name sortKey="Schaller, Hg" uniqKey="Schaller H">HG Schaller</name></author><author><name sortKey="Hirsch, C" uniqKey="Hirsch C">C Hirsch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wilson, Ib" uniqKey="Wilson I">IB Wilson</name></author><author><name sortKey="Cleary, Pd" uniqKey="Cleary P">PD Cleary</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Oral Investig</journal-id><journal-id journal-id-type="iso-abbrev">Clin Oral Investig</journal-id><journal-title-group><journal-title>Clinical Oral Investigations</journal-title></journal-title-group><issn pub-type="ppub">1432-6981</issn><issn pub-type="epub">1436-3771</issn><publisher><publisher-name>Springer-Verlag</publisher-name><publisher-loc>Berlin/Heidelberg</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">22290063</article-id><article-id pub-id-type="pmc">3585945</article-id><article-id pub-id-type="publisher-id">888</article-id><article-id pub-id-type="doi">10.1007/s00784-012-0888-9</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>What is known about the influence of dentine hypersensitivity on oral health-related quality of life?</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Bekes</surname><given-names>Katrin</given-names></name><address><phone>+49-345-5571141</phone><fax>+49-345-5571142</fax><email>katrin.bekes@medizin.uni-halle.de</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Hirsch</surname><given-names>Christian</given-names></name><xref ref-type="aff" rid="Aff2"></xref></contrib><aff id="Aff1"><label></label>Department of Operative Dentistry and Periodontology, Department of Pediatric Dentistry, Martin-Luther-University Halle-Wittenberg, University School of Dental Medicine, Harz 42a, 06108 Halle, Germany</aff><aff id="Aff2"><label></label>Department of Pediatric Dentistry, University of Leipzig, Liebigstraße 10 – 14, House 1, 04103 Leipzig, Germany</aff></contrib-group><pub-date pub-type="epub"><day>6</day><month>12</month><year>2012</year></pub-date><pub-date pub-type="pmc-release"><day>6</day><month>12</month><year>2012</year></pub-date><pub-date pub-type="ppub"><month>3</month><year>2013</year></pub-date><volume>17</volume><issue>Suppl 1</issue><fpage>45</fpage><lpage>51</lpage><history><date date-type="received"><day>1</day><month>12</month><year>2011</year></date><date date-type="accepted"><day>21</day><month>11</month><year>2012</year></date></history><permissions><copyright-statement>© Springer-Verlag Berlin Heidelberg 2012</copyright-statement></permissions><abstract id="Abs1"><sec><title>Objectives</title><p>Oral health-related quality of life is a relatively new but rapidly growing concept in dentistry. It is an aspect of dental health addressing the patient’s perception of whether his/her current oral health status has an impact upon his/her actual quality of life. Dentine hypersensitivity (DHS), which is a common condition of transient tooth pain associated with a variety of exogenous stimuli, may disturb the patient during eating, drinking, toothbrushing and sometimes even breathing. The resulting restrictions on everyday activities can have an important effect on the patient’s quality of life. The aims of this paper were to consider the concept of oral health-related quality of life and to review and discuss the literature on oral health-related quality of life and DHS.</p></sec><sec><title>Material and methods</title><p>A PubMed literature research was conducted using the terms (“dentin sensitivity” [MeSH Terms] OR (“dentin” [All Fields] AND “sensitivity” [All Fields]) OR “dentin sensitivity” [All Fields]) AND ((“oral health” [MeSH Terms] OR (“oral” [All Fields] AND “health” [All Fields]) OR “oral health” [All Fields]) AND related [All Fields] AND (“quality of life” [MeSH Terms] OR (“quality” [All Fields] AND “life” [All Fields]) OR “quality of life” [All Fields])). Furthermore, a manual search was carried out. Any relevant work published presenting pertinent information about the described issue was considered for inclusion in the review.</p></sec><sec><title>Results</title><p>The combination of the search terms resulted in a list of only three titles. The few published studies convincingly demonstrated that oral health-related quality of life is negatively affected in patients suffering from DHS.</p></sec><sec><title>Conclusions</title><p>Patients with sensitive teeth report substantial oral health-related quality of life (OHRQoL) impairment. Nevertheless, knowledge about the influence of DHS on oral health-related quality of life is incomplete and, therefore, needs further research.</p></sec><sec><title>Clinical relevance</title><p>Oral diseases can lead to physical, psychological and social disability. This paper shows that DHS can have a negative impact on the patients’ OHRQoL.</p></sec></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>Oral health-related quality of life (OHRQoL)</kwd><kwd>Dentine hypersensitivity</kwd><kwd>Oral Health Impact Profile (OHIP)</kwd><kwd>Dentine Hypersensitivity Experience Questionnaire (DHEQ)</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© Springer-Verlag Berlin Heidelberg 2013</meta-value></custom-meta></custom-meta-group></article-meta></front><body><sec id="Sec1" sec-type="introduction"><title>Introduction</title><sec id="Sec2"><title>Quality of life, health-related quality of life and oral health-related quality of life</title><p>Quality of life (QoL) research has gained increasing attention in medicine and dentistry in recent years, undergoing a quantum shift. Where it was once regarded as a secondary outcome, occasionally useful to complement biologic and clinical markers of disease, QoL issues are now at the forefront of public health policy [<xref ref-type="bibr" rid="CR1">1</xref>]. Quality of life can be defined as an individual’s perception of his/her position in life, in the context of the culture and value systems in which he/she lives and in relation to his/her expectations, goals and concerns [<xref ref-type="bibr" rid="CR2">2</xref>]. In 2003, Allen noted that “there appears to be an association between health and quality of life, which is not clearly defined, and the term health related quality of life is used to describe this association” [<xref ref-type="bibr" rid="CR3">3</xref>]. Although the term health-related quality of life has no strict definition, there is consensus that it is a multidimensional construct capturing people’s perceptions about factors that are important in their everyday lives [<xref ref-type="bibr" rid="CR1">1</xref>].</p><p>Oral health-related quality of life (OHRQoL) is a part of health-related quality of life that focuses on oral health and orofacial concerns. It describes the way in which oral health affects a person’s ability to function, psychological status, social factors and pain or discomfort [<xref ref-type="bibr" rid="CR4">4</xref>]. Therefore, the OHRQoL attempts to represent the subjective side of oral health. Not surprisingly, as with health-related quality of life, the term OHRQoL has no strict definition [<xref ref-type="bibr" rid="CR5">5</xref>]. However, it is generally agreed that it is also a multidimensional concept. The definitions for OHRQoL that are available vary from simple to more rigorous. One example of a simple definition is the one provided by the U.S. Surgeon General’s report on oral health, which defines OHRQoL as “a multidimensional construct that reflects (among other things) people’s comfort when eating, sleeping, and engaging in social interaction; their self-esteem; and their satisfaction with respect to their oral health” [<xref ref-type="bibr" rid="CR6">6</xref>].</p></sec><sec id="Sec3"><title>Concepts of oral health</title><p>Traditional methods to measure oral health are based on clinical standards. As in medicine, clinical dental indicators and indices of disease are used as an inverse measure of oral health in dentistry. These indices provide a quantitative method for measuring, scoring and analysing dental conditions in individuals and groups. An index describes the status of individuals or groups with respect to the condition to be measured. For example, the gingival index [<xref ref-type="bibr" rid="CR7">7</xref>] and periodontal index [<xref ref-type="bibr" rid="CR8">8</xref>] are used to describe periodontal diseases, and the DMFT index (number of decayed, missing and filled teeth) is used to describe a person’s dental caries experience [<xref ref-type="bibr" rid="CR9">9</xref>]. However, as important as these objective measures are, they only reflect the endpoint of the disease processes [<xref ref-type="bibr" rid="CR3">3</xref>]. They also focus on the mouth rather than the person and give no indication of their impact on an individual’s daily life and general health [<xref ref-type="bibr" rid="CR5">5</xref>].</p><p>The limitations of this paradigm of oral health have been recognised, principally that this model only deals with disease [<xref ref-type="bibr" rid="CR3">3</xref>]. Thus, Locker developed a conceptual framework for measuring oral health status that is based on the World Health Organization classification of impairment, disability and handicap and attempts to capture all possible functional and psychosocial outcomes of oral disorders [<xref ref-type="bibr" rid="CR10">10</xref>]. In this model, disease can lead to impairment, which may then lead to a functional limitation or pain/discomfort, either physical or psychological. Either of these outcomes may lead to physical, psychological or social disability, which is defined by Locker as any limitation in or lack of ability to perform activities of daily living. As a final consequence, handicap can occur. It is characterised by social disadvantage, e.g. social isolation. Functional limitation may also lead directly to handicap [<xref ref-type="bibr" rid="CR10">10</xref>].</p></sec><sec id="Sec4"><title>Measuring oral health-related quality of life</title><p>OHRQoL can be measured using a questionnaire approach. Results can serve as an outcome measure; they allow insight into how a patient’s oral health affects his/her well-being and quality of life at a given point in time [<xref ref-type="bibr" rid="CR11">11</xref>]. Multiple-item questionnaires are the most widely used method to assess OHRQoL. Researchers have developed several quality of life instruments specific to oral health, and the number continues to grow rapidly to comply with the demand for more specific measures [<xref ref-type="bibr" rid="CR5">5</xref>].</p><p>Slade and Spencer developed the Oral Health Impact Profile (OHIP), which differs from other measures in that it is based on both Locker’s conceptual framework as well as input from dental patients with a variety of oral conditions [<xref ref-type="bibr" rid="CR12">12</xref>]. The OHIP is the most widely used instrument in studies evaluating OHRQoL. The questionnaire attempts to measure the effects of both the frequency and the severity of oral problems on functional and psychosocial well-being. The OHIP has 49 items that are grouped into seven subscales: functional limitation, pain, psychological discomfort, physical disability, psychological disability, social disability and handicap. For each OHIP item, the patient is asked how frequently he/she experienced the impact of that item during last month. Responses concerning item impact are given using an ordinal rating scale (0 = never, 1 = hardly ever, 2 = occasionally, 3 = fairly often, 4 = very often). The summary score (sum of item responses resulting in a range of 0–4 × 49 = 0–196) represents a “problem index” that characterises the OHRQoL. A “0” summary score indicates the absence of any problems, higher OHIP scores represent more impaired OHRQoL, and a summary score of “196” indicates that all problems are experienced very often. The patient’s score can be evaluated by comparison to a table of standard values representative of different populations.</p><p>The OHIP is a technically sophisticated OHRQoL instrument that is widely used internationally [<xref ref-type="bibr" rid="CR12">12</xref>, <xref ref-type="bibr" rid="CR13">13</xref>]. Several language versions already exist (e.g. Spanish [<xref ref-type="bibr" rid="CR14">14</xref>], Swedish [<xref ref-type="bibr" rid="CR15">15</xref>], Chinese [<xref ref-type="bibr" rid="CR16">16</xref>], German [<xref ref-type="bibr" rid="CR17">17</xref>] and Hungarian [<xref ref-type="bibr" rid="CR18">18</xref>]) and initial evidence for the instrument’s cross-cultural equivalence is available [<xref ref-type="bibr" rid="CR14">14</xref>–<xref ref-type="bibr" rid="CR18">18</xref>]. The questionnaire has been applied several times, including in patients with temporomandibular disorders [<xref ref-type="bibr" rid="CR19">19</xref>, <xref ref-type="bibr" rid="CR20">20</xref>], xerostomia [<xref ref-type="bibr" rid="CR21">21</xref>], burning mouth syndrome [<xref ref-type="bibr" rid="CR22">22</xref>], tooth agenesis [<xref ref-type="bibr" rid="CR23">23</xref>] and HIV infection [<xref ref-type="bibr" rid="CR24">24</xref>, <xref ref-type="bibr" rid="CR25">25</xref>]. Clinical trials have also used the OHIP to evaluate implant-supported prostheses [<xref ref-type="bibr" rid="CR26">26</xref>, <xref ref-type="bibr" rid="CR27">27</xref>] and steroidal therapy for oral lichen planus [<xref ref-type="bibr" rid="CR28">28</xref>]. However, regarding the condition of dentine hypersensitivity (DHS) and OHRQoL (and especially the OHIP), the literature is limited.</p></sec><sec id="Sec5"><title>DHS and its influence on oral health-related quality of life</title><p>DHS is an oral complaint frequently reported in clinical dental practice. It is characterised by a short and sharp pain that occurs in the presence of thermal, chemical, evaporative, tactile or osmotic stimuli, ceases after their removal and cannot be explained as arising from any other form of dental defect or pathology [<xref ref-type="bibr" rid="CR29">29</xref>, <xref ref-type="bibr" rid="CR30">30</xref>]. From the relatively few studies that have been concerned with the prevalence of DHS, it can be concluded that it is a frequent condition [<xref ref-type="bibr" rid="CR31">31</xref>]. Depending on the patient group and the study design, prevalences of 4–57 % up to 60–98 % have been reported [<xref ref-type="bibr" rid="CR32">32</xref>, <xref ref-type="bibr" rid="CR33">33</xref>]. In a national survey in Germany, 39 % of middle-aged adults reported problems with hypersensitive teeth [<xref ref-type="bibr" rid="CR34">34</xref>]. Pain is the major symptom of the condition. The degree of discomfort depends on the individual’s pain perception and pain tolerance, as well as emotional and physical factors. Whereas many affected individuals do not seek treatment to desensitise their teeth because they do not perceive DHS to be a severe oral health problem [<xref ref-type="bibr" rid="CR35">35</xref>], studies have indicated that a substantial segment of patients (10–25 %) do seek treatment, complaining of different causes of discomfort, such as pain while consuming hot or cold foods and beverages (coffee, ice cream), during toothbrushing or sometimes even while breathing [<xref ref-type="bibr" rid="CR36">36</xref>, <xref ref-type="bibr" rid="CR37">37</xref>]. From the perspective of the patients, these symptoms and problems are highly relevant. The restrictions on everyday activities can have an important effect on their overall quality of life [<xref ref-type="bibr" rid="CR10">10</xref>]. However, relatively little research on DHS has been reported.</p></sec></sec><sec id="Sec6" sec-type="materials|methods"><title>Material and methods</title><p>A review of the literature revealed that few studies about the influence of DHS on OHRQoL have been conducted in any country. A PubMed search and a manual search through the end of October 2011 were conducted using the terms (“dentin sensitivity” [MeSH Terms] OR (“dentin” [All Fields] AND “sensitivity” [All Fields]) OR “dentin sensitivity” [All Fields]) AND ((“oral health” [MeSH Terms] OR (“oral” [All Fields] AND “health” [All Fields]) OR “oral health” [All Fields]) AND related [All Fields] AND (“quality of life” [MeSH Terms] OR (“quality” [All Fields] AND “life” [All Fields]) OR “quality of life” [All Fields])) with no language restrictions. Any relevant work published presenting pertinent information about the described issue was considered for inclusion in the review.</p></sec><sec id="Sec7" sec-type="results"><title>Results</title><p>The combination of the search terms resulted in a list of only three titles [<xref ref-type="bibr" rid="CR38">38</xref>–<xref ref-type="bibr" rid="CR40">40</xref>]. Two of these articles were published in English, and one was published in German (Table <xref rid="Tab1" ref-type="table">1</xref>). The German publication and one of the English publications were carried out by the same study group. Although the number of articles was limited, a considerable heterogeneity was found between both study groups with regard to study design and patient characteristics. Furthermore, different instruments were used for the assessment of OHRQoL. One study group used the widely used OHIP to describe OHRQoL in patients with DHS and then to measure the efficacy of treatment intervention on OHRQoL in these patients. The other study group developed a completely new instrument, the Dentine Hypersensitivity Experience Questionnaire (DHEQ).<table-wrap id="Tab1"><label>Table 1</label><caption><p>Characteristics of the three published studies examining dentine hypersensitivity and OHRQoL</p></caption><table frame="hsides" rules="groups"><thead><tr><th>Study</th><th>OHRQoL-related instrument</th><th>Patient recruitment</th><th>Inclusion criteria</th><th>Exclusion criteria</th><th><italic>n</italic></th><th>OHRQoL outcomes</th><th>Author’s OHRQoL-related conclusion</th></tr></thead><tbody><tr><td rowspan="2">Bekes et al. [<xref ref-type="bibr" rid="CR38">38</xref>]</td><td rowspan="2">OHIP-G49</td><td>Dental offices in Germany that participated in previous oral hygiene studies conducted by GABA International</td><td rowspan="2">Patients presenting at dental offices because of hypersensitive teeth and reacting positive to an air stimulus applied by the dentist</td><td rowspan="2">Patients with removable partial dentures, with more than five missing OHIP questionnaire answers overall, with more than two missing answers in any OHIP domain</td><td>656</td><td rowspan="2">Patients with dentine hypersensitivity showed statistically significantly higher OHIP summary scores compared with the general population</td><td rowspan="2">The oral condition of hypersensitive teeth is significantly associated with impaired OHRQoL</td></tr><tr><td>General population: subjects without removable partial dentures from a national German general population sample</td><td>1,541 (control)</td></tr><tr><td>Bekes et al. [<xref ref-type="bibr" rid="CR40">40</xref>]</td><td>OHIP-G49</td><td>See Bekes et al. [<xref ref-type="bibr" rid="CR38">38</xref>]</td><td rowspan="3">see Bekes et al. [<xref ref-type="bibr" rid="CR38">38</xref>]</td><td></td><td>713; no control</td><td>90 % of the patients showed an improvement of OHRQoL</td><td>A 21-day home use of the elmex SENSITIVE Care System improves OHRQoL in subjects with hypersensitive teeth</td></tr><tr><td rowspan="2">Boiko et al. (2010) [<xref ref-type="bibr" rid="CR39">39</xref>]</td><td rowspan="2">DHEQ</td><td>Patients with clinically diagnosed dentine hypersensitivity recruited at preintervention stage in a sponsored randomised controlled trial, before the participants received any interventions or other study procedures</td><td>More than 10 % of the item missing in the questionnaire</td><td>108</td><td rowspan="2">DHEQ shows good psychometric properties in both a general population and clinical sample</td><td rowspan="2">The use of DHEQ can further the understanding of the subjective impacts of dentine hypersensitivity</td></tr><tr><td>General population: adults recruited from the general population via online advertisements at the University of Sheffield and across the UK</td><td>More than 10 % of the item missing in the questionnaire</td><td>160 (control)</td></tr></tbody></table></table-wrap></p><p>Using the German version of the OHIP, the OHIP-G, Bekes et al. [<xref ref-type="bibr" rid="CR38">38</xref>] evaluated OHRQoL impairment in patients seeking care for their hypersensitive teeth in comparison with general population subjects [<xref ref-type="bibr" rid="CR12">12</xref>, <xref ref-type="bibr" rid="CR17">17</xref>]. Study participants were 656 patients without removable prosthodontics who sought treatment for their hypersensitive teeth in German dental offices. These patients were asked to complete the OHIP-G prior to treatment. The sum of OHIP-G item responses (OHIP-G49, 0–196) characterised the OHRQoL impairment. Patients’ OHIP summary scores were analysed and compared with those in a sample of the German general population (<italic>n</italic> = 1,541). It was found that the distribution of OHIP-G summary scores in patients with DHS and in general population was different. The general population subjects had an OHIP-G median score of 5, while the patient group had an OHIP-G median score of 30. The 10 % of the subjects with the highest OHIP-G summary scores presented scores of 36 or higher (general population) and 66 or higher (patients). The mean OHIP-G summary score value of the study participants from the general population was 12.2 (±18.4), while the patients’ mean OHIP-G summary score was 34.5 (±22.6). The difference was statistically significant (<italic>P</italic> < 0.001). Mean OHIP summary scores indicated that patients with hypersensitive teeth reported considerably more impaired OHRQoL (approximately 22 OHIP units) than subjects in the general population. It was also found that the influence of gender depended on the population (i.e. female general population subjects had lower OHIP scores than male general population subjects, and female patients had higher OHIP scores than male patients). A relationship between age and OHIP-G summary scores was also observed in both patients with hypersensitive teeth and general population subjects. In the general population, older subjects (40+ years) reported statistically significantly (<italic>P</italic> < 0.001) more problems (i.e. higher OHIP-G summary scores) than younger subjects (15–39 years). In the patient group, the difference between younger and older patients was similar in magnitude to that in the general population and close to statistical significance (<italic>P</italic> = 0.08).</p><p>The results show that DHS is related to substantially impaired OHRQoL. Moreover, this study is the first one evaluating the impact of this oral condition with a widely used patient-centred outcome measure, such as the OHIP, to characterise the broader influence of this condition on patients’ perceived oral health. The authors discuss that the results refer to patients seeking care for their condition and that they cannot be generalised to individuals suffering from DHS but not seeking care. Moreover, they note that it has to be taken into account that the results refer to general dentists and may not be generalised to health professionals who are more trained or calibrated in the assessment of DHS. However, the authors suggest that the setting is representative for typical patients where the general dentist is confronted with providing diagnosis and treatment for the challenging clinical problem of DHS.</p><p>In a second investigation, the same study group used the OHIP-G to describe OHRQoL in patients with hypersensitive teeth before and after treatment intervention [<xref ref-type="bibr" rid="CR40">40</xref>]. In a field trial, 713 patients from Germany presenting at 161 dental offices and seeking care for DHS were given the elmex SENSITIVE Care System to use for their oral hygiene twice a day for 21 days. The system included elmex SENSITIVE toothpaste, elmex SENSITIVE dental rinse and the elmex interX SENSITIVE toothbrush. The patients completed the OHIP-G before and after treatment intervention. The authors found a considerable improvement of OHRQoL in 90 % of patients, with 50 % of the patients showing a decrease of 11 or more OHIP units. The mean change was 13.5 OHIP-G units and was statistically significant (<italic>P</italic> < 0.001). Little difference based on gender or age was present. The results showed that a 21-day home use of the elmex SENSITIVE Care System improved OHRQoL in subjects with hypersensitive teeth. Certainly, the study has limitations. It was not randomised and did not include a control or placebo group. Nevertheless, it is the first study evaluating the effect of a DHS treatment not only from the clinical view of the dentist, but also from the patient’s perspective. The results suggest that it is possible to measure the success of a treatment for DHS with the OHIP.</p><p>The third study focusing on OHRQoL and DHS found in the literature was conducted by Boiko et al. [<xref ref-type="bibr" rid="CR39">39</xref>] in the UK. These authors did not use the well-established OHIP as an OHRQoL instrument, but instead developed and validated a new condition-specific measure of OHRQoL for DHS, the DHEQ. This instrument aims to measure particular everyday impacts on OHRQoL related to DHS. The study group constructed a questionnaire using a multistaged impact approach and an explicit theoretical model. As a result, the DHEQ questionnaire has 48 items containing a description of the pain, a scale to capture subjective impacts of DHS, a global oral health rating and a scale to record effects on overall life. The description of the pain contains nine items and each item is treated separately. The impact scale has six subscales based on the initial domains of the Wilson and Cleary model [<xref ref-type="bibr" rid="CR41">41</xref>]: restrictions, approach coping, avoidance coping, social impact, emotional impact and identity. Two summary measures can be created for the impact scale and its subscales. The total score is calculated as the sum of the item scores per participant (possible range 0–243). Subscale scores for each of the subscales can be created in the same way. The extent of impacts are calculated as the number of impacts per participant to which each participant broadly agrees (“strongly agree” to “strongly disagree”). The global oral health rating contains one item, the scale to record effects on overall life four items. The higher the total score of the DHEQ is, the more impaired is the patient’s OHRQoL. In the study, the DHEQ was applied in a general population sample (<italic>n</italic> = 160) and in a sample of patients clinically diagnosed with DHS (<italic>n</italic> = 108). The DHEQ showed good psychometric properties in both samples and demonstrated that patients with DHS had higher scores on the DHEQ than the general population, indicating that these patients have impaired OHRQoL. The authors concluded that the DHEQ provides an alternative to generic OHRQoL instruments because of its direct reference to the problems associated with sensitive teeth, and its use can further the understanding of the subjective impacts of DHS.</p><p>As this publication introduced this new instrument and focused on the psychometric properties of the instrument, it has not been applied in any other study yet. In addition, the effects of DHS treatment interventions on OHRQoL have yet to be measured using the DHEQ. Future studies will need to examine this measurement tool translated in other languages so that results can be compared cross-culturally before it will be accepted internationally. Because this instrument is a special measurement tool that can only be used for the condition of DHS, its utility is limited to this special patient group. Therefore, it is not possible—in contrast to the OHIP—to use the DHEQ to measure OHRQoL in patients with other oral diseases.</p></sec><sec id="Sec8" sec-type="conclusion"><title>Conclusion</title><p>The concept of OHRQoL brings a new perspective to clinical care and research. It shifts the focus of clinicians and researchers from the oral cavity alone to the patient as a whole. OHRQoL allows insight into how a patient’s oral health affects his/her well-being and quality of life at a given point in time. It can be measured with standardised validated questionnaires (e.g. the OHIP). Thus, different oral diseases and oral complaints can be compared directly.</p><p>Although knowledge about the influence of DHS on OHRQoL is incomplete and has not been systematically studied, the following conclusions can be drawn:<list list-type="bullet"><list-item><p>OHRQoL assessment provides additional information about the magnitude of the condition of hypersensitive teeth and should be used in addition to clinical tests to assess the severity and impact of the problem.</p></list-item><list-item><p>Patients with sensitive teeth report substantial OHRQoL impairment. This finding may have an influence on whether or how patients should be treated.</p></list-item><list-item><p>The influence of oral pain, regardless of the location, on subjects’ perceived oral health is considerable.</p></list-item></list></p></sec><sec id="Sec9"><title>Clinical relevance</title><p>Oral diseases can lead to physical, psychological and social disability. 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