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<title xml:lang="en">Evaluation of Effect of Astringent on Oral Mucosa as a Non-surgical Preprosthetic Treatment Modality in Edentulous Patients: An In Vivo Study</title>
<author>
<name sortKey="Radke, Usha" sort="Radke, Usha" uniqKey="Radke U" first="Usha" last="Radke">Usha Radke</name>
<affiliation>
<nlm:aff id="Aff1">Department of Prosthodontics, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kahar, Anita" sort="Kahar, Anita" uniqKey="Kahar A" first="Anita" last="Kahar">Anita Kahar</name>
<affiliation>
<nlm:aff id="Aff1">Department of Prosthodontics, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Zade, Prajakta" sort="Zade, Prajakta" uniqKey="Zade P" first="Prajakta" last="Zade">Prajakta Zade</name>
<affiliation>
<nlm:aff id="Aff2">Department of Oral & Maxillofacial Pathology & Microbiology, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Lambade, Dipti" sort="Lambade, Dipti" uniqKey="Lambade D" first="Dipti" last="Lambade">Dipti Lambade</name>
<affiliation>
<nlm:aff id="Aff1">Department of Prosthodontics, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Deshpande, Saee" sort="Deshpande, Saee" uniqKey="Deshpande S" first="Saee" last="Deshpande">Saee Deshpande</name>
<affiliation>
<nlm:aff id="Aff1">Department of Prosthodontics, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Radke, Pranjal" sort="Radke, Pranjal" uniqKey="Radke P" first="Pranjal" last="Radke">Pranjal Radke</name>
<affiliation>
<nlm:aff id="Aff1">Department of Prosthodontics, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</nlm:aff>
</affiliation>
</author>
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<idno type="pmid">26199497</idno>
<idno type="pmc">4502035</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502035</idno>
<idno type="RBID">PMC:4502035</idno>
<idno type="doi">10.1007/s13191-014-0372-0</idno>
<date when="2014">2014</date>
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<title xml:lang="en" level="a" type="main">Evaluation of Effect of Astringent on Oral Mucosa as a Non-surgical Preprosthetic Treatment Modality in Edentulous Patients: An In Vivo Study</title>
<author>
<name sortKey="Radke, Usha" sort="Radke, Usha" uniqKey="Radke U" first="Usha" last="Radke">Usha Radke</name>
<affiliation>
<nlm:aff id="Aff1">Department of Prosthodontics, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kahar, Anita" sort="Kahar, Anita" uniqKey="Kahar A" first="Anita" last="Kahar">Anita Kahar</name>
<affiliation>
<nlm:aff id="Aff1">Department of Prosthodontics, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Zade, Prajakta" sort="Zade, Prajakta" uniqKey="Zade P" first="Prajakta" last="Zade">Prajakta Zade</name>
<affiliation>
<nlm:aff id="Aff2">Department of Oral & Maxillofacial Pathology & Microbiology, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Lambade, Dipti" sort="Lambade, Dipti" uniqKey="Lambade D" first="Dipti" last="Lambade">Dipti Lambade</name>
<affiliation>
<nlm:aff id="Aff1">Department of Prosthodontics, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Deshpande, Saee" sort="Deshpande, Saee" uniqKey="Deshpande S" first="Saee" last="Deshpande">Saee Deshpande</name>
<affiliation>
<nlm:aff id="Aff1">Department of Prosthodontics, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Radke, Pranjal" sort="Radke, Pranjal" uniqKey="Radke P" first="Pranjal" last="Radke">Pranjal Radke</name>
<affiliation>
<nlm:aff id="Aff1">Department of Prosthodontics, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">The Journal of the Indian Prosthodontic Society</title>
<idno type="ISSN">0972-4052</idno>
<idno type="eISSN">1998-4057</idno>
<imprint>
<date when="2014">2014</date>
</imprint>
</series>
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<div type="abstract" xml:lang="en">
<p>Preprosthetic treatments are advocated in edentulous patients to enhance the denture bearing areas for good denture support. Most of the times the preprosthetic treatments are considered only in a surgical way. Ideally every edentulous patient undergoing complete denture treatment needs a non-surgical preprosthetic treatment. So that, the denture bearing area will be properly prepared before the denture construction. The present study was conducted on thirty completely edentulous male patients who had visited to our Institute for the treatment. Each patient was asked to massage with astringent gel on the denture bearing mucosa over a 4 weeks period. Exfoliative cytology was used to collect the surface cells from the palatal mucosa. First scrape was taken before the stimulation treatment was started. The second and third scrape was taken after the stimulation treatment with astringent gel for each patient. In this way total 90 scrapes were made and the each smear was stained with the Papanicolaou’s technique to examine under light microscope. About 100 cells were counted from each stained smear. The number of parabasal cells, intermediate cells and superficial cells were recorded to calculate the degree of keratinization. Statistical analysis was performed. A significant difference (
<italic>p</italic>
 < 0.001) in keratinization levels was found. The mean percentage of superficial cells before the stimulation treatment was 79.80 %; this percentage was gradually increased to 84.60 and 90.57 % after the 2  and 4 weeks period of stimulation treatment respectively with astringent gel.</p>
</div>
</front>
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<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">J Indian Prosthodont Soc</journal-id>
<journal-id journal-id-type="iso-abbrev">J Indian Prosthodont Soc</journal-id>
<journal-title-group>
<journal-title>The Journal of the Indian Prosthodontic Society</journal-title>
</journal-title-group>
<issn pub-type="ppub">0972-4052</issn>
<issn pub-type="epub">1998-4057</issn>
<publisher>
<publisher-name>Springer India</publisher-name>
<publisher-loc>New Delhi</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">26199497</article-id>
<article-id pub-id-type="pmc">4502035</article-id>
<article-id pub-id-type="publisher-id">372</article-id>
<article-id pub-id-type="doi">10.1007/s13191-014-0372-0</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Evaluation of Effect of Astringent on Oral Mucosa as a Non-surgical Preprosthetic Treatment Modality in Edentulous Patients: An In Vivo Study</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Radke</surname>
<given-names>Usha</given-names>
</name>
<address>
<email>usha.radke@gmail.com</email>
</address>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kahar</surname>
<given-names>Anita</given-names>
</name>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Zade</surname>
<given-names>Prajakta</given-names>
</name>
<xref ref-type="aff" rid="Aff2"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Lambade</surname>
<given-names>Dipti</given-names>
</name>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Deshpande</surname>
<given-names>Saee</given-names>
</name>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Radke</surname>
<given-names>Pranjal</given-names>
</name>
<xref ref-type="aff" rid="Aff1"></xref>
</contrib>
<aff id="Aff1">
<label></label>
Department of Prosthodontics, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</aff>
<aff id="Aff2">
<label></label>
Department of Oral & Maxillofacial Pathology & Microbiology, VSPM’s Dental College & Research Centre, Nagpur, Maharashtra India</aff>
</contrib-group>
<pub-date pub-type="epub">
<day>5</day>
<month>6</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="ppub">
<month>12</month>
<year>2014</year>
</pub-date>
<volume>14</volume>
<issue>Suppl 1</issue>
<fpage>93</fpage>
<lpage>97</lpage>
<history>
<date date-type="received">
<day>15</day>
<month>10</month>
<year>2013</year>
</date>
<date date-type="accepted">
<day>19</day>
<month>5</month>
<year>2014</year>
</date>
</history>
<permissions>
<copyright-statement>© Indian Prosthodontic Society 2014</copyright-statement>
</permissions>
<abstract id="Abs1">
<p>Preprosthetic treatments are advocated in edentulous patients to enhance the denture bearing areas for good denture support. Most of the times the preprosthetic treatments are considered only in a surgical way. Ideally every edentulous patient undergoing complete denture treatment needs a non-surgical preprosthetic treatment. So that, the denture bearing area will be properly prepared before the denture construction. The present study was conducted on thirty completely edentulous male patients who had visited to our Institute for the treatment. Each patient was asked to massage with astringent gel on the denture bearing mucosa over a 4 weeks period. Exfoliative cytology was used to collect the surface cells from the palatal mucosa. First scrape was taken before the stimulation treatment was started. The second and third scrape was taken after the stimulation treatment with astringent gel for each patient. In this way total 90 scrapes were made and the each smear was stained with the Papanicolaou’s technique to examine under light microscope. About 100 cells were counted from each stained smear. The number of parabasal cells, intermediate cells and superficial cells were recorded to calculate the degree of keratinization. Statistical analysis was performed. A significant difference (
<italic>p</italic>
 < 0.001) in keratinization levels was found. The mean percentage of superficial cells before the stimulation treatment was 79.80 %; this percentage was gradually increased to 84.60 and 90.57 % after the 2  and 4 weeks period of stimulation treatment respectively with astringent gel.</p>
</abstract>
<kwd-group xml:lang="en">
<title>Keywords</title>
<kwd>Preprosthetic treatment</kwd>
<kwd>Non-surgical</kwd>
<kwd>Astringent</kwd>
<kwd>Exfoliative cytology</kwd>
<kwd>Keratinization</kwd>
<kwd>Denture bearing areas</kwd>
</kwd-group>
<custom-meta-group>
<custom-meta>
<meta-name>issue-copyright-statement</meta-name>
<meta-value>© Indian Prosthodontic Society 2014</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
</record>

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