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<title xml:lang="en">Multicentric Squamous Odontogenic Tumor: A Case Report and Review of the Literature</title>
<author>
<name sortKey="Elmuradi, Sophia" sort="Elmuradi, Sophia" uniqKey="Elmuradi S" first="Sophia" last="Elmuradi">Sophia Elmuradi</name>
<affiliation>
<nlm:aff id="Aff1">
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<institution-id institution-id-type="ISNI">0000 0004 1936 9887</institution-id>
<institution-id institution-id-type="GRID">grid.273335.3</institution-id>
<institution>Department of Oral Diagnostic Sciences, University at Buffalo,</institution>
<institution>The State University of New York,</institution>
</institution-wrap>
355 Squire Hall, Buffalo, 14214 NY USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Mair, Yasmin" sort="Mair, Yasmin" uniqKey="Mair Y" first="Yasmin" last="Mair">Yasmin Mair</name>
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<nlm:aff id="Aff1">
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<institution-id institution-id-type="ISNI">0000 0004 1936 9887</institution-id>
<institution-id institution-id-type="GRID">grid.273335.3</institution-id>
<institution>Department of Oral Diagnostic Sciences, University at Buffalo,</institution>
<institution>The State University of New York,</institution>
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355 Squire Hall, Buffalo, 14214 NY USA</nlm:aff>
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<author>
<name sortKey="Suresh, Lakshmanan" sort="Suresh, Lakshmanan" uniqKey="Suresh L" first="Lakshmanan" last="Suresh">Lakshmanan Suresh</name>
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<institution>IMMCO Diagnostics, Inc,</institution>
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Buffalo, NY USA</nlm:aff>
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<name sortKey="Desantis, James" sort="Desantis, James" uniqKey="Desantis J" first="James" last="Desantis">James Desantis</name>
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<nlm:aff id="Aff3">Oral and Maxillofacial Surgeon, Private Practice, Johnson City, NY USA</nlm:aff>
</affiliation>
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<author>
<name sortKey="Neiders, Mirdza" sort="Neiders, Mirdza" uniqKey="Neiders M" first="Mirdza" last="Neiders">Mirdza Neiders</name>
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Buffalo, NY USA</nlm:aff>
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<name sortKey="Aguirre, Alfredo" sort="Aguirre, Alfredo" uniqKey="Aguirre A" first="Alfredo" last="Aguirre">Alfredo Aguirre</name>
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355 Squire Hall, Buffalo, 14214 NY USA</nlm:aff>
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<idno type="doi">10.1007/s12105-016-0753-2</idno>
<date when="2016">2016</date>
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<title xml:lang="en" level="a" type="main">Multicentric Squamous Odontogenic Tumor: A Case Report and Review of the Literature</title>
<author>
<name sortKey="Elmuradi, Sophia" sort="Elmuradi, Sophia" uniqKey="Elmuradi S" first="Sophia" last="Elmuradi">Sophia Elmuradi</name>
<affiliation>
<nlm:aff id="Aff1">
<institution-wrap>
<institution-id institution-id-type="ISNI">0000 0004 1936 9887</institution-id>
<institution-id institution-id-type="GRID">grid.273335.3</institution-id>
<institution>Department of Oral Diagnostic Sciences, University at Buffalo,</institution>
<institution>The State University of New York,</institution>
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355 Squire Hall, Buffalo, 14214 NY USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Mair, Yasmin" sort="Mair, Yasmin" uniqKey="Mair Y" first="Yasmin" last="Mair">Yasmin Mair</name>
<affiliation>
<nlm:aff id="Aff1">
<institution-wrap>
<institution-id institution-id-type="ISNI">0000 0004 1936 9887</institution-id>
<institution-id institution-id-type="GRID">grid.273335.3</institution-id>
<institution>Department of Oral Diagnostic Sciences, University at Buffalo,</institution>
<institution>The State University of New York,</institution>
</institution-wrap>
355 Squire Hall, Buffalo, 14214 NY USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Suresh, Lakshmanan" sort="Suresh, Lakshmanan" uniqKey="Suresh L" first="Lakshmanan" last="Suresh">Lakshmanan Suresh</name>
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<nlm:aff id="Aff2">
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<institution-id institution-id-type="GRID">grid.420897.0</institution-id>
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<institution>IMMCO Diagnostics, Inc,</institution>
</institution-wrap>
Buffalo, NY USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Desantis, James" sort="Desantis, James" uniqKey="Desantis J" first="James" last="Desantis">James Desantis</name>
<affiliation>
<nlm:aff id="Aff3">Oral and Maxillofacial Surgeon, Private Practice, Johnson City, NY USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Neiders, Mirdza" sort="Neiders, Mirdza" uniqKey="Neiders M" first="Mirdza" last="Neiders">Mirdza Neiders</name>
<affiliation>
<nlm:aff id="Aff2">
<institution-wrap>
<institution-id institution-id-type="GRID">grid.420897.0</institution-id>
<institution></institution>
<institution>IMMCO Diagnostics, Inc,</institution>
</institution-wrap>
Buffalo, NY USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Aguirre, Alfredo" sort="Aguirre, Alfredo" uniqKey="Aguirre A" first="Alfredo" last="Aguirre">Alfredo Aguirre</name>
<affiliation>
<nlm:aff id="Aff1">
<institution-wrap>
<institution-id institution-id-type="ISNI">0000 0004 1936 9887</institution-id>
<institution-id institution-id-type="GRID">grid.273335.3</institution-id>
<institution>Department of Oral Diagnostic Sciences, University at Buffalo,</institution>
<institution>The State University of New York,</institution>
</institution-wrap>
355 Squire Hall, Buffalo, 14214 NY USA</nlm:aff>
</affiliation>
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<title level="j">Head and Neck Pathology</title>
<idno type="ISSN">1936-055X</idno>
<idno type="eISSN">1936-0568</idno>
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<date when="2016">2016</date>
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<div type="abstract" xml:lang="en">
<p> Squamous odontogenic tumor (SOT) is a rare benign epithelial odontogenic neoplasm of the jaws. Both intraosseous and peripheral SOTs have been described in the English language literature. While most intraosseous SOTs occur as solitary lesions, a multicentric variant has also been previously described. Although the radiographic and microscopic features are identical for both solitary and multicentric clinical presentations, there are three significant differences between them. More specifically, multicentric SOT presents at an earlier age (third decade of life), has a slightly higher male to female ratio than the solitary type and has a marked predilection for African–Americans. Here we document the eighth reported case of multicentric SOT, which was diagnosed in a 43-year-old African–American male. In addition, we feature focal sebaceous metaplasia, a heretofore unknown microscopic feature of SOT. Clinical, radiological, and histopathological findings are discussed. The differential diagnosis, biological behavior and management modalities for SOT are also addressed.</p>
</div>
</front>
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<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Head Neck Pathol</journal-id>
<journal-id journal-id-type="iso-abbrev">Head Neck Pathol</journal-id>
<journal-title-group>
<journal-title>Head and Neck Pathology</journal-title>
</journal-title-group>
<issn pub-type="ppub">1936-055X</issn>
<issn pub-type="epub">1936-0568</issn>
<publisher>
<publisher-name>Springer US</publisher-name>
<publisher-loc>New York</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">27632187</article-id>
<article-id pub-id-type="pmc">5429276</article-id>
<article-id pub-id-type="publisher-id">753</article-id>
<article-id pub-id-type="doi">10.1007/s12105-016-0753-2</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Original Paper</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Multicentric Squamous Odontogenic Tumor: A Case Report and Review of the Literature</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Elmuradi</surname>
<given-names>Sophia</given-names>
</name>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Mair</surname>
<given-names>Yasmin</given-names>
</name>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Suresh</surname>
<given-names>Lakshmanan</given-names>
</name>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>DeSantis</surname>
<given-names>James</given-names>
</name>
<xref ref-type="aff" rid="Aff3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Neiders</surname>
<given-names>Mirdza</given-names>
</name>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid">http://orcid.org/0000-0003-2331-9324</contrib-id>
<name>
<surname>Aguirre</surname>
<given-names>Alfredo</given-names>
</name>
<address>
<phone>(716) 829-3553</phone>
<email>aguirr@buffalo.edu</email>
</address>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<aff id="Aff1">
<label>1</label>
<institution-wrap>
<institution-id institution-id-type="ISNI">0000 0004 1936 9887</institution-id>
<institution-id institution-id-type="GRID">grid.273335.3</institution-id>
<institution>Department of Oral Diagnostic Sciences, University at Buffalo,</institution>
<institution>The State University of New York,</institution>
</institution-wrap>
355 Squire Hall, Buffalo, 14214 NY USA</aff>
<aff id="Aff2">
<label>2</label>
<institution-wrap>
<institution-id institution-id-type="GRID">grid.420897.0</institution-id>
<institution></institution>
<institution>IMMCO Diagnostics, Inc,</institution>
</institution-wrap>
Buffalo, NY USA</aff>
<aff id="Aff3">
<label>3</label>
Oral and Maxillofacial Surgeon, Private Practice, Johnson City, NY USA</aff>
</contrib-group>
<pub-date pub-type="epub">
<day>8</day>
<month>9</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="collection">
<month>6</month>
<year>2017</year>
</pub-date>
<volume>11</volume>
<issue>2</issue>
<fpage>168</fpage>
<lpage>174</lpage>
<history>
<date date-type="received">
<day>6</day>
<month>6</month>
<year>2016</year>
</date>
<date date-type="accepted">
<day>31</day>
<month>8</month>
<year>2016</year>
</date>
</history>
<permissions>
<copyright-statement>© Springer Science+Business Media New York 2016</copyright-statement>
</permissions>
<abstract id="Abs1">
<p> Squamous odontogenic tumor (SOT) is a rare benign epithelial odontogenic neoplasm of the jaws. Both intraosseous and peripheral SOTs have been described in the English language literature. While most intraosseous SOTs occur as solitary lesions, a multicentric variant has also been previously described. Although the radiographic and microscopic features are identical for both solitary and multicentric clinical presentations, there are three significant differences between them. More specifically, multicentric SOT presents at an earlier age (third decade of life), has a slightly higher male to female ratio than the solitary type and has a marked predilection for African–Americans. Here we document the eighth reported case of multicentric SOT, which was diagnosed in a 43-year-old African–American male. In addition, we feature focal sebaceous metaplasia, a heretofore unknown microscopic feature of SOT. Clinical, radiological, and histopathological findings are discussed. The differential diagnosis, biological behavior and management modalities for SOT are also addressed.</p>
</abstract>
<kwd-group xml:lang="en">
<title>Keywords</title>
<kwd>Odontogenic</kwd>
<kwd>Tumor</kwd>
<kwd>Squamous</kwd>
<kwd>Multicentric</kwd>
</kwd-group>
<custom-meta-group>
<custom-meta>
<meta-name>issue-copyright-statement</meta-name>
<meta-value>© Springer Science+Business Media New York 2017</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
</record>

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