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Efficacy of the Cyclodextrin Liquid Preparation of Itraconazole in Treatment of Denture Stomatitis: Comparison with Itraconazole Capsules

Identifieur interne : 000992 ( Pmc/Corpus ); précédent : 000991; suivant : 000993

Efficacy of the Cyclodextrin Liquid Preparation of Itraconazole in Treatment of Denture Stomatitis: Comparison with Itraconazole Capsules

Auteurs : L. J. Cross ; J. Bagg ; T. C. Aitchison

Source :

RBID : PMC:89697

Abstract

This study investigated the efficacy of a cyclodextrin solution of itraconazole in the treatment of Candida-associated denture stomatitis. It was found that the liquid and capsule preparations of itraconazole were equally effective adjuncts in the treatment of this condition. However, the side effect profile indicates that capsules are the preferred formulation.


Url:
PubMed: 10639376
PubMed Central: 89697

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PMC:89697

Le document en format XML

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<name sortKey="Aitchison, T C" sort="Aitchison, T C" uniqKey="Aitchison T" first="T. C." last="Aitchison">T. C. Aitchison</name>
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<p>This study investigated the efficacy of a cyclodextrin solution of itraconazole in the treatment of
<italic>Candida</italic>
-associated denture stomatitis. It was found that the liquid and capsule preparations of itraconazole were equally effective adjuncts in the treatment of this condition. However, the side effect profile indicates that capsules are the preferred formulation.</p>
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<journal-id journal-id-type="nlm-ta">Antimicrob Agents Chemother</journal-id>
<journal-id journal-id-type="publisher-id">ANTIMICROB AGENTS CHEMOTHER</journal-id>
<journal-title>Antimicrobial Agents and Chemotherapy</journal-title>
<issn pub-type="ppub">0066-4804</issn>
<issn pub-type="epub">1098-6596</issn>
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<publisher-name>American Society for Microbiology</publisher-name>
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<article-id pub-id-type="pmid">10639376</article-id>
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<subject>Clinical Therapeutics</subject>
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<series-title>Note</series-title>
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<title-group>
<article-title>Efficacy of the Cyclodextrin Liquid Preparation of Itraconazole in Treatment of Denture Stomatitis: Comparison with Itraconazole Capsules</article-title>
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<contrib contrib-type="author">
<name>
<surname>Cross</surname>
<given-names>L. J.</given-names>
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<xref ref-type="aff" rid="N0x8a56120.0x9e44728">1</xref>
<xref ref-type="author-notes" rid="FN150">*</xref>
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<name>
<surname>Bagg</surname>
<given-names>J.</given-names>
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<xref ref-type="aff" rid="N0x8a56120.0x9e44728">1</xref>
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<contrib contrib-type="author">
<name>
<surname>Aitchison</surname>
<given-names>T. C.</given-names>
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<aff id="N0x8a56120.0x9e44728"> University of Glasgow Dental School, Glasgow G2 3JZ,
<sup>1</sup>
and Department of Statistics, University of Glasgow, Glasgow G12 8QW,
<sup>2</sup>
Scotland</aff>
<author-notes>
<fn id="FN150">
<label>*</label>
<p>Corresponding author. Mailing address: Level 2, Glasgow Dental Hospital & School NHS Trust, 378 Sauchiehall St., Glasgow G2 3JZ, Scotland. Phone: 44 0141 211 9831. Fax: 44 0141 353 1593. E-mail:
<email>L.Cross@dental.gla.ac.uk</email>
.</p>
</fn>
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<pub-date pub-type="ppub">
<month>2</month>
<year>2000</year>
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<volume>44</volume>
<issue>2</issue>
<fpage>425</fpage>
<lpage>427</lpage>
<history>
<date date-type="received">
<day>10</day>
<month>8</month>
<year>1999</year>
</date>
<date date-type="rev-request">
<day>16</day>
<month>8</month>
<year>1999</year>
</date>
<date date-type="accepted">
<day>3</day>
<month>11</month>
<year>1999</year>
</date>
</history>
<copyright-statement>Copyright © 2000, American Society for Microbiology</copyright-statement>
<copyright-year>2000</copyright-year>
<abstract>
<p>This study investigated the efficacy of a cyclodextrin solution of itraconazole in the treatment of
<italic>Candida</italic>
-associated denture stomatitis. It was found that the liquid and capsule preparations of itraconazole were equally effective adjuncts in the treatment of this condition. However, the side effect profile indicates that capsules are the preferred formulation.</p>
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