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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Orthodontic Treatment of Malocclusion and its Impact on Oral Health-Related Quality of Life</title><author><name sortKey="Jamilian, Abdolreza" sort="Jamilian, Abdolreza" uniqKey="Jamilian A" first="Abdolreza" last="Jamilian">Abdolreza Jamilian</name><affiliation><nlm:aff id="aff1">Department of Orthodontics, Tehran Dental Branch, Center of Craniofacial Research, Islamic Azad University, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Kiaee, Bita" sort="Kiaee, Bita" uniqKey="Kiaee B" first="Bita" last="Kiaee">Bita Kiaee</name><affiliation><nlm:aff id="aff2">Departments of Orthodontics, Tehran Dental Branch, Islamic Azad University. Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Sanayei, Shabnam" sort="Sanayei, Shabnam" uniqKey="Sanayei S" first="Shabnam" last="Sanayei">Shabnam Sanayei</name><affiliation><nlm:aff id="aff2">Departments of Orthodontics, Tehran Dental Branch, Islamic Azad University. Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Khosravi, Saeed" sort="Khosravi, Saeed" uniqKey="Khosravi S" first="Saeed" last="Khosravi">Saeed Khosravi</name><affiliation><nlm:aff id="aff3">Department of Languages, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Perillo, Letizia" sort="Perillo, Letizia" uniqKey="Perillo L" first="Letizia" last="Perillo">Letizia Perillo</name><affiliation><nlm:aff id="aff4">Departments of Orthodontics, Second University of Naples, Naples, Italy</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27386009</idno><idno type="pmc">4911751</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911751</idno><idno type="RBID">PMC:4911751</idno><idno type="doi">10.2174/1874210601610010236</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000748</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000748</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Orthodontic Treatment of Malocclusion and its Impact on Oral Health-Related Quality of Life</title><author><name sortKey="Jamilian, Abdolreza" sort="Jamilian, Abdolreza" uniqKey="Jamilian A" first="Abdolreza" last="Jamilian">Abdolreza Jamilian</name><affiliation><nlm:aff id="aff1">Department of Orthodontics, Tehran Dental Branch, Center of Craniofacial Research, Islamic Azad University, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Kiaee, Bita" sort="Kiaee, Bita" uniqKey="Kiaee B" first="Bita" last="Kiaee">Bita Kiaee</name><affiliation><nlm:aff id="aff2">Departments of Orthodontics, Tehran Dental Branch, Islamic Azad University. Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Sanayei, Shabnam" sort="Sanayei, Shabnam" uniqKey="Sanayei S" first="Shabnam" last="Sanayei">Shabnam Sanayei</name><affiliation><nlm:aff id="aff2">Departments of Orthodontics, Tehran Dental Branch, Islamic Azad University. Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Khosravi, Saeed" sort="Khosravi, Saeed" uniqKey="Khosravi S" first="Saeed" last="Khosravi">Saeed Khosravi</name><affiliation><nlm:aff id="aff3">Department of Languages, Tehran University of Medical Sciences, Tehran, Iran</nlm:aff></affiliation></author><author><name sortKey="Perillo, Letizia" sort="Perillo, Letizia" uniqKey="Perillo L" first="Letizia" last="Perillo">Letizia Perillo</name><affiliation><nlm:aff id="aff4">Departments of Orthodontics, Second University of Naples, Naples, Italy</nlm:aff></affiliation></author></analytic><series><title level="j">The Open Dentistry Journal</title><idno type="eISSN">1874-2106</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objectives:</title><p>Malocclusion, though not life-threatening, has vast impact on individual’s social interactions and self-esteem. Therefore, the aim of the current study was to assess whether orthodontic treatment of adolescents with malocclusion had any association with their oral health-related quality of life (OHRQoL).</p></sec><sec><title>Methods:</title><p>The subjects for this study were recruited at a state-funded university clinic. Data were collected from 100 participants aged 17 to 21 with moderate to severe malocclusion. Experimental group comprised of 50 subjects who were in the retention phase of their orthodontic treatment and the control group comprised of 50 untreated subjects. The shortened version of the Oral Health Impacts Profile (OHIP-14) as used to assess the subjects’ oral health-related impact. T-test, Kruskal-Wallis, and Mann Whitney tests were used to analyze the data and <italic>p</italic>-value was set at <italic>P</italic> < 0.05.</p></sec><sec><title>Results:</title><p>In general, oral health-related quality of life of all subjects significantly improved after orthodontic treatment. (<italic>p</italic><0.001) Subjects with moderate malocclusion showed better improvement than severe malocclusion subjects. (<italic>P</italic><0.001)</p></sec><sec><title>Conclusion:</title><p>This study showed that oral health-related quality of life improves with the treatment of malocclusion.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Mohlin, B" uniqKey="Mohlin B">B. Mohlin</name></author><author><name sortKey="Al Saadi, E" uniqKey="Al Saadi E">E. al-Saadi</name></author><author><name sortKey="Andrup, L" uniqKey="Andrup L">L. Andrup</name></author><author><name sortKey="Ekblom, K" uniqKey="Ekblom K">K. Ekblom</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Perillo, L" uniqKey="Perillo L">L. Perillo</name></author><author><name sortKey="Esposito, M" uniqKey="Esposito M">M. Esposito</name></author><author><name sortKey="Contiello, M" uniqKey="Contiello M">M. 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Masucci</name></author><author><name sortKey="Ferro, F" uniqKey="Ferro F">F. Ferro</name></author><author><name sortKey="Apicella, D" uniqKey="Apicella D">D. Apicella</name></author><author><name sortKey="Baccetti, T" uniqKey="Baccetti T">T. Baccetti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jamilian, A" uniqKey="Jamilian A">A. Jamilian</name></author><author><name sortKey="Darnahal, A" uniqKey="Darnahal A">A. Darnahal</name></author><author><name sortKey="Damani, E" uniqKey="Damani E">E. Damani</name></author><author><name sortKey="Talaeipour, M" uniqKey="Talaeipour M">M. Talaeipour</name></author><author><name sortKey="Kamali, Z" uniqKey="Kamali Z">Z. Kamali</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sergl, H G" uniqKey="Sergl H">H.G. Sergl</name></author><author><name sortKey="Klages, U" uniqKey="Klages U">U. Klages</name></author><author><name sortKey="Zentner, A" uniqKey="Zentner A">A. 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Etezad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Slade, G D" uniqKey="Slade G">G.D. Slade</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ravaghi, V" uniqKey="Ravaghi V">V. Ravaghi</name></author><author><name sortKey="Farrahi Avval, N" uniqKey="Farrahi Avval N">N. Farrahi-Avval</name></author><author><name sortKey="Locker, D" uniqKey="Locker D">D. Locker</name></author><author><name sortKey="Underwood, M" uniqKey="Underwood M">M. Underwood</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cicciu, M" uniqKey="Cicciu M">M. Cicciù</name></author><author><name sortKey="Matacena, G" uniqKey="Matacena G">G. Matacena</name></author><author><name sortKey="Signorino, F" uniqKey="Signorino F">F. Signorino</name></author><author><name sortKey="Brugaletta, A" uniqKey="Brugaletta A">A. Brugaletta</name></author><author><name sortKey="Cicciu, A" uniqKey="Cicciu A">A. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Open Dent J</journal-id><journal-id journal-id-type="iso-abbrev">Open Dent J</journal-id><journal-id journal-id-type="publisher-id">TODENTJ</journal-id><journal-title-group><journal-title>The Open Dentistry Journal</journal-title></journal-title-group><issn pub-type="epub">1874-2106</issn><publisher><publisher-name>Bentham Open</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27386009</article-id><article-id pub-id-type="pmc">4911751</article-id><article-id pub-id-type="publisher-id">TODENTJ-10-236</article-id><article-id pub-id-type="doi">10.2174/1874210601610010236</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Orthodontic Treatment of Malocclusion and its Impact on Oral Health-Related Quality of Life</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Jamilian</surname><given-names>Abdolreza</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Kiaee</surname><given-names>Bita</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Sanayei</surname><given-names>Shabnam</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Khosravi</surname><given-names>Saeed</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Perillo</surname><given-names>Letizia</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib></contrib-group><aff id="aff1"><label>1</label>Department of Orthodontics, Tehran Dental Branch, Center of Craniofacial Research, Islamic Azad University, Tehran, Iran</aff><aff id="aff2"><label>2</label>Departments of Orthodontics, Tehran Dental Branch, Islamic Azad University. Tehran, Iran</aff><aff id="aff3"><label>3</label>Department of Languages, Tehran University of Medical Sciences, Tehran, Iran</aff><aff id="aff4"><label>4</label>Departments of Orthodontics, Second University of Naples, Naples, Italy</aff><author-notes><corresp id="cor1"><label>*</label> Address correspondence to this author at the No. 2713, Vali Asr St. Tehran 1966843133, Iran;
Tel: 0098-21-22011892; Fax: 0098-21-22022215, E-mail: <email xlink:href="info@jamilian.net">info@jamilian.net</email></corresp></author-notes><pub-date pub-type="epub"><day>31</day><month>5</month><year>2016</year></pub-date><pub-date pub-type="collection"><year>2016</year></pub-date><volume>10</volume><fpage>236</fpage><lpage>241</lpage><history><date date-type="received"><day>25</day><month>2</month><year>2015</year></date><date date-type="rev-recd"><day>28</day><month>4</month><year>2016</year></date><date date-type="accepted"><day>28</day><month>4</month><year>2016</year></date></history><permissions><copyright-statement>© Jamilian <italic>et al.</italic>; Licensee <italic>Bentham Open.</italic></copyright-statement><copyright-year>2016</copyright-year><copyright-holder>Bentham Open</copyright-holder><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/legalcode"><license-p>This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (<uri xlink:type="simple" xlink:href="https://creativecommons.org/licenses/by-nc/4.0/legalcode">https://creativecommons.org/licenses/by-nc/4.0/legalcode</uri>), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.</license-p></license></permissions><abstract><sec><title>Objectives:</title><p>Malocclusion, though not life-threatening, has vast impact on individual’s social interactions and self-esteem. Therefore, the aim of the current study was to assess whether orthodontic treatment of adolescents with malocclusion had any association with their oral health-related quality of life (OHRQoL).</p></sec><sec><title>Methods:</title><p>The subjects for this study were recruited at a state-funded university clinic. Data were collected from 100 participants aged 17 to 21 with moderate to severe malocclusion. Experimental group comprised of 50 subjects who were in the retention phase of their orthodontic treatment and the control group comprised of 50 untreated subjects. The shortened version of the Oral Health Impacts Profile (OHIP-14) as used to assess the subjects’ oral health-related impact. T-test, Kruskal-Wallis, and Mann Whitney tests were used to analyze the data and <italic>p</italic>-value was set at <italic>P</italic> < 0.05.</p></sec><sec><title>Results:</title><p>In general, oral health-related quality of life of all subjects significantly improved after orthodontic treatment. (<italic>p</italic><0.001) Subjects with moderate malocclusion showed better improvement than severe malocclusion subjects. (<italic>P</italic><0.001)</p></sec><sec><title>Conclusion:</title><p>This study showed that oral health-related quality of life improves with the treatment of malocclusion.</p></sec></abstract><kwd-group><title>Keywords</title><kwd>Malocclusion</kwd><kwd>OHIP</kwd><kwd>OHRQoL</kwd><kwd>Orthodontic treatment</kwd><kwd>Quality of life</kwd></kwd-group></article-meta></front><body><sec sec-type="intro"><title>INTRODUCTION</title><p>Malocclusion in itself is not a life threatening condition; however, it may unfavorably affect social interactions and psychological well-being of patients [<xref rid="R1" ref-type="bibr">1</xref>-<xref rid="R3" ref-type="bibr">3</xref>]. </p><p>Index of Orthodontic Treatment Need (IOTN) was proposed by Brook and Shaw [<xref rid="R4" ref-type="bibr">4</xref>] in the United Kingdom as a scoring system for estimating treatment need of patients with various degrees of malocclusion. The IOTN has been used extensively in the literature to evaluate actual and perceptive orthodontic treatment needs [<xref rid="R5" ref-type="bibr">5</xref>, <xref rid="R6" ref-type="bibr"> 6</xref>]. Various studies have also evaluated IOTN and its impact on quality of life. Quality of life (QoL) has been defined by the World Health Organization as “people’s perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards, and concerns”. Additionally, oral health-related quality of life (OHRQoL) describes the impact of oral and paraoral conditions on one’s life. Recognizing the effects of orthodontic treatment on the quality of life is an important step in informing the patients of the health benefits and gains of orthodontic treatment [<xref rid="R7" ref-type="bibr">7</xref>]. </p><p>Several studies have investigated the effects of orthodontic treatment on OHRQoL between treated patients and untreated control groups [<xref rid="R8" ref-type="bibr">8</xref>]. de Oliveira and Sheiham studied the impact of orthodontic treatment on oral health-related quality of life in Brazilian adolescents and found better oral health-related quality of life in adolescents who had completed orthodontic treatment [<xref rid="R9" ref-type="bibr">9</xref>]. However, Taylor <italic>et al</italic>. [<xref rid="R10" ref-type="bibr">10</xref>] did not find any significant association between orthodontic treatment of malocclusion and oral health related quality of life despite the improvement in the health, appearance, social well-being and oral function of the patients. Johal <italic>et al</italic>. [<xref rid="R11" ref-type="bibr">11</xref>] also assessed the impact of orthodontic treatment on OHRQoL in adults and found that during the first 3 months of treatment fixed orthodontic therapy had a negative impact on the OHRQoL of the patients, which was followed by an improvement in comparison with the pre-treatment scores.</p><p>Given the disagreements in the literature and lack of proper data the aim of this study was to compare the effects of malocclusion and its orthodontic treatment on the quality of life of adolescents.</p></sec><sec sec-type="materials|methods"><title>MATERIALS AND METHODS</title><p>This historical cohort study received approval from the Human Research Ethics Committee of Islamic Azad University of medical sciences (IAU). Prior to data collection, only the subjects who agreed to participate by signing a statement of informed consent were included in the study. </p><p>A sample size calculation was carried out using data of a study investigating effects of malocclusion and its orthodontic treatment on the quality of life of adolescents and other similar studies which used convenient clinical samples for their study [<xref rid="R3" ref-type="bibr">3</xref>, <xref rid="R10" ref-type="bibr"> 10</xref>]. It was estimated that a sample size of 46 subjects was needed to demonstrate a significant change in OHRQoL, with an 80 per cent probability power at the 5% level of significance. Considering possible dropouts, the samples size was increased by 10%; resulting in a final sample size of 50 participants.</p><p>The samples were selected from people who were referred to orthodontic department of IAU from February to August 2012. Inclusion criteria was moderate to severe malocclusion using Index of Orthodontic Treatment Need (IOTN) grades of 3 and 4 [<xref rid="R4" ref-type="bibr">4</xref>, <xref rid="R12" ref-type="bibr"> 12</xref>], age range of 17 to 21 years, and having the same socioeconomic factors including sex, race, social class, and level of education. None of the patients had undergone orthognathic surgery. Due to the strict inclusion criteria the final sample consisted of 100 subjects. The experimental group consisted of 50 subjects who had undergone orthodontic treatment for 2 years for treatment of their moderate to severe malocclusion. The control group included 50 untreated patients who had moderate to severe malocclusions. In both groups 25 of the subjects had moderate malocclusion (IOTN=Grade 3) and 25 of them had severe malocclusion (IOTN=Grade 4). Table <bold><xref ref-type="table" rid="T1">1</xref></bold> shows IOTN grading used in the study and Table <bold><xref ref-type="table" rid="T2">2</xref></bold> depicts the demographic and occlusion characteristics of the samples.</p><p>The samples were asked to complete questionnaires incorporating the Short Form Oral Health Impact Profile (OHIP-14) [<xref rid="R13" ref-type="bibr">13</xref>-<xref rid="R16" ref-type="bibr">16</xref>], which is a 14-items questionnaire designed to measure self-reported functional limitation, discomfort and disability attributed to oral conditions. It is derived from an original extended version of 49-items [<xref rid="R17" ref-type="bibr">17</xref>]. The experimental group subjects filled out the forms two months after completion of their treatment in their retention phase and the control group subjects filled them out before the start of their treatment. Responses to the 14 items of OHIP were recorded in a 5-point Likert scale (0= never, 1= hardly ever, 2= occasionally, 3 = fairly often, 4 = very often). The scores ranged from 0 to 56. Therefore, higher OHIP-14 scores represent more negative effects of oral health on the quality of life. The Statistical Package for Social Sciences, Version 20 (SPSS Inc. Chicago, Illinois, USA) was used to analyze the data. T-test, Kruskal-Wallis, and Mann Whitney tests were used to analyze the data and p-value was set at <italic>P</italic> < 0.05.</p></sec><sec sec-type="results"><title>RESULTS</title><p>Table <bold><xref ref-type="table" rid="T2">2</xref></bold> shows that there were no statistically significant differences in gender, age, and severity of the malocclusions between the two groups. Subjects with moderate malocclusion who had undergone orthodontic treatment had the lowest mean score of 1.12 ± 1.69; while, the control group subjects with severe malocclusion had the highest mean score of 20.76 ± 6.64. Kruskal-Wallis test showed that mean scores of treated subjects were significantly lower than control group which is indicative of lower OHRQoL in subjects who haven’t undergone orthodontic treatment (<italic>P</italic><0.001) (Table <bold><xref ref-type="table" rid="T3">3</xref></bold>). However, in Table <bold><xref ref-type="table" rid="T4">4</xref></bold> Man-Whitney test shows that even after treatment subjects with sever malocclusion had lower OHRQoL than the subjects with moderate malocclusion.</p></sec><sec sec-type="discussion"><title>DISCUSSION</title><p>OHIP-14 questionnaire showed that untreated moderate to severe malocclusions have a negative impact on the quality of life of adolescents. </p><p>This finding is consistent with previous studies, which indicate that Brazilian adolescents who had undergone orthodontic treatment had less physical, psychological, and social complications associated with malocclusion in comparison with those who had no history of orthodontics [<xref rid="R18" ref-type="bibr">18</xref>]. Silvola <italic>et al</italic>. [<xref rid="R19" ref-type="bibr">19</xref>] found that the treatment of severe malocclusion significantly improved oral health-related quality of life of the patients. Foster <italic>et al</italic>. [<xref rid="R20" ref-type="bibr">20</xref>] examined the relationship between clinical characteristics (such as caries experience and malocclusion) and oral health-related quality of life (OHRQoL) in adolescents in New Zealand and could not find any relationship between caries experience and OHRQoL, while they found that malocclusion directly affects OHRQoL. de Oliveira <italic>et al</italic>. [<xref rid="R9" ref-type="bibr">9</xref>] found that completion of orthodontic treatment had a positive impact on the oral health-related quality of life of adolescents. Nonetheless, quite interestingly, they found that orthodontic treatment may have negative impacts on quality of life during the treatment and suggested that orthodontists should be aware of this impact caused by treatment and regularly remind patients of the positive outcomes. On the other hand, Taylor <italic>et al</italic>. [<xref rid="R10" ref-type="bibr">10</xref>] found that malocclusion and orthodontic treatment do not have any measurable effects on the OHRQoL. They mentioned that an explanation of their different finding could be what psychologists call a “hedonic treadmill” [<xref rid="R21" ref-type="bibr">21</xref>]. According to their study many believe that well-being has a fixed set point for each person that cannot easily be changed. And because orthodontic treatment takes place over several years, patients might have forgotten their initial condition and cannot evaluate their progress, or they might have already adapted to the final occlusal and esthetic outcome and, thus, there is no impact on OHRQoL. Therefore, changes in psychological measures after orthodontic treatment should not be expected [<xref rid="R10" ref-type="bibr">10</xref>]. </p><p>On the contrary, our study showed that oral health-related quality of life improves as the occlusion is improved. Nonetheless, it should be noted that subjects with severe malocclusion showed lower OHRQoL improvement after orthodontic treatment in comparison with more moderate subjects. The reason for this might lie in the fact that although these subjects rejected surgery they still had the assumption that they would have benefited more from surgical correction. </p><p>One of the limitations to this study was that were no pretreatment OHRQoL assessments of treated subjects and longitudinal data on pre and post treatment could improve the results of the study. </p></sec><sec sec-type="conclusion"><title>CONCLUSION</title><p>Subjects with moderate to severe malocclusion with no history of orthodontic treatment had more negative OHRQoL than adolescents who had completed orthodontic treatment. </p></sec></body><back><ack><title>ACKNOWLEDGEMENTS</title><p>Declared none.</p></ack><sec><title>CONFLICT OF INTEREST</title><p>The authors confirm that this article content has no conflict of interest.</p></sec><ref-list><title>REFERENCES</title><ref id="R1"><label>1</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Mohlin</surname><given-names>B.</given-names></name><name><surname>al-Saadi</surname><given-names>E.</given-names></name><name><surname>Andrup</surname><given-names>L.</given-names></name><name><surname>Ekblom</surname><given-names>K.</given-names></name></person-group><article-title>Orthodontics in 12-year old children. 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(more than 1 tooth missing in any quadrant) requiring pre-restorative orthodontics.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">5•a</td><td valign="bottom" rowspan="1" colspan="1">Increased overjet greater than 9 mm.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">5•m</td><td valign="bottom" rowspan="1" colspan="1">Reverse overjet greater than 3.5 mm with reported masticatory and speech difficulties.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">5•p</td><td valign="bottom" rowspan="1" colspan="1">Defects of cleft lip and palate and other craniofacial anomalies.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">5•s</td><td valign="bottom" rowspan="1" colspan="1">Submerged deciduous teeth.</td></tr><tr><td colspan="3" valign="bottom" align="left" rowspan="1"><bold>Grade 4 (Severe/Need treatment)</bold></td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">4•h</td><td valign="bottom" rowspan="1" colspan="1">Less extensive hypodontia requiring pre-restorative orthodontics or orthodontic space closure to obviate the need for a prosthesis.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">4•a</td><td valign="bottom" rowspan="1" colspan="1">Increased overjet greater than 6 mm, but less than or equal to 9 mm.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">4•b</td><td valign="bottom" rowspan="1" colspan="1">Reverse overjet greater than 3.5 mm with no masticatory or speech difficulties.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">4•m</td><td valign="bottom" rowspan="1" colspan="1">Reverse overjet greater than 1 mm but less than 3.5 mm with recorded masticatory and speech difficulties.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">4•c</td><td valign="bottom" rowspan="1" colspan="1">Anterior or posterior crossbites with greater than 2 mm discrepancy between retruded contact position and intercuspal position.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">4•l</td><td valign="bottom" rowspan="1" colspan="1">Posterior lingual crossbite with no functional occlusal contact in one or both buccal segments.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">4•d</td><td valign="bottom" rowspan="1" colspan="1">Severe contact point displacements greater than 4 mm.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">4•e</td><td valign="bottom" rowspan="1" colspan="1">Extreme lateral or anterior open bites greater than 4 mm.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">4•f</td><td valign="bottom" rowspan="1" colspan="1">Increased and complete overbite with gingival or palatal trauma.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">4•t</td><td valign="bottom" rowspan="1" colspan="1">Partially erupted teeth, tipped and impacted against adjacent teeth.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">4•x</td><td valign="bottom" rowspan="1" colspan="1">Presence of supernumerary teeth.</td></tr><tr><td colspan="3" valign="middle" align="left" rowspan="1">Grade 3 (Moderate/Borderline need)</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">3•a</td><td valign="bottom" rowspan="1" colspan="1">Increased overjet greater than 3.5 mm, but less than or equal to 6 mm with incompetent lips.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">3•b</td><td valign="bottom" rowspan="1" colspan="1">Reverse overjet greater than 1 mm, but less than or equal to 3.5 mm.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">3•c </td><td valign="bottom" rowspan="1" colspan="1">Anterior or posterior crossbites with greater than 1 mm, but less than or equal to 2 mm discrepancy between retruded contact position and intercuspal position.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">3•d</td><td valign="bottom" rowspan="1" colspan="1">Contact point displacements greater than 2 mm, but less than or equal to 4 mm.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">3•e</td><td valign="bottom" rowspan="1" colspan="1">Lateral or anterior open bite greater than 2 mm, but less than or equal to 4 mm.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">3•f</td><td valign="bottom" rowspan="1" colspan="1">Deep overbite complete on gingival or palatal tissues, but no trauma.</td></tr><tr><td colspan="3" valign="middle" align="left" rowspan="1"><bold>Grade 2 (Mild/Little Need)</bold></td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">2•a</td><td valign="bottom" rowspan="1" colspan="1">Increased overjet greater than 3.5 mm, but less than or equal to 6 mm with competent lips.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">2•b</td><td valign="bottom" rowspan="1" colspan="1">Reverse overjet greater than 0 mm but less than or equal to 1 mm.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">2•c</td><td valign="bottom" rowspan="1" colspan="1">Anterior or posterior crossbite with less than or equal to 1 mm discrepancy between retruded contact position and intercuspal position.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">2•d</td><td valign="bottom" rowspan="1" colspan="1">Contact point displacements greater than 1 mm but less than or equal to 2 mm.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">2•e</td><td valign="bottom" rowspan="1" colspan="1">Anterior or posterior open bite greater than 1 mm but less than or equal to 2 mm.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">2•f</td><td valign="bottom" rowspan="1" colspan="1">Increased overbite greater than or equal to 3.5 mm without gingival contact.</td></tr><tr><td colspan="2" valign="middle" align="center" rowspan="1">2•g</td><td valign="bottom" rowspan="1" colspan="1">Pre- or post-normal occlusions with no other anomalies (includes up to half a unit discrepancy).</td></tr><tr><td colspan="3" valign="middle" align="left" rowspan="1"><bold>Grade 1 (No Need)</bold></td></tr><tr><td valign="middle" align="center" rowspan="1" colspan="1">1•</td><td colspan="2" valign="bottom" rowspan="1">Extremely minor malocclusions including contact point displacements less than 1 mm.</td></tr></table></table-wrap><table-wrap id="T2" position="float"><label>Table 2</label><caption><p>Demographic characteristics of the subjects.</p></caption><table frame="border" rules="all" width="100%"><thead><tr><th rowspan="2" align="center" colspan="1">Group</th><th colspan="2" align="center" rowspan="1">Severity of Malocclusion</th><th colspan="2" align="center" rowspan="1">Gender</th><th align="center" rowspan="1" colspan="1">Age</th></tr><tr><th align="center" rowspan="1" colspan="1">IOTN Grade</th><th align="center" rowspan="1" colspan="1">Number</th><th align="center" rowspan="1" colspan="1">Male</th><th align="center" rowspan="1" colspan="1">Female</th><th align="center" rowspan="1" colspan="1"> </th></tr></thead><tbody><tr><td rowspan="2" align="center" valign="middle" colspan="1">Experimental</td><td align="center" rowspan="1" colspan="1">3 (Moderate)</td><td align="center" rowspan="1" colspan="1">25</td><td align="center" rowspan="1" colspan="1"> 8</td><td align="center" rowspan="1" colspan="1"> 17</td><td align="center" rowspan="1" colspan="1">19.96 ± 4.1</td></tr><tr><td align="center" rowspan="1" colspan="1">4 (Severe)</td><td align="center" rowspan="1" colspan="1">25</td><td align="center" rowspan="1" colspan="1"> 6</td><td align="center" rowspan="1" colspan="1"> 19</td><td align="center" rowspan="1" colspan="1">19.2 ± 3.64</td></tr><tr><td rowspan="2" align="center" valign="middle" colspan="1">Control</td><td align="center" rowspan="1" colspan="1">3 (Moderate)</td><td align="center" rowspan="1" colspan="1">25</td><td align="center" rowspan="1" colspan="1"> 10</td><td align="center" rowspan="1" colspan="1"> 15</td><td align="center" rowspan="1" colspan="1">18.32 ± 3.66</td></tr><tr><td align="center" rowspan="1" colspan="1">4 (Severe)</td><td align="center" rowspan="1" colspan="1">25</td><td align="center" rowspan="1" colspan="1"> 9</td><td align="center" rowspan="1" colspan="1"> 16</td><td align="center" rowspan="1" colspan="1">19.32 ± 4.35</td></tr><tr><td colspan="3" align="center" rowspan="1">P Value</td><td colspan="2" align="center" rowspan="1">0.7</td><td align="center" rowspan="1" colspan="1">0.5</td></tr></tbody></table></table-wrap><table-wrap id="T3" position="float"><label>Table 3</label><caption><p>Scores of OHRQoL based on OHIP-14.</p></caption><table frame="border" rules="all" width="100%"><thead><tr><th align="center" rowspan="1" colspan="1">Group</th><th align="center" rowspan="1" colspan="1">IOTN Grade</th><th align="center" rowspan="1" colspan="1">Mean scores</th></tr></thead><tbody><tr><td rowspan="2" align="center" valign="middle" colspan="1">Experimental </td><td align="center" rowspan="1" colspan="1">3 (Moderate)</td><td align="center" rowspan="1" colspan="1">1.12 ± 1.69</td></tr><tr><td align="center" rowspan="1" colspan="1">4 (Severe)</td><td align="center" rowspan="1" colspan="1">3.88 ± 3.22</td></tr><tr><td rowspan="2" align="center" valign="middle" colspan="1">Control</td><td align="center" rowspan="1" colspan="1">3 (Moderate)</td><td align="center" rowspan="1" colspan="1">8.25 ± 3.88</td></tr><tr><td align="center" rowspan="1" colspan="1">4 (Severe)</td><td align="center" rowspan="1" colspan="1">20.76 ± 6.64</td></tr><tr><td align="center" colspan="2" rowspan="1"><italic>P</italic> Value</td><td align="center" rowspan="1" colspan="1">0.001</td></tr></tbody></table></table-wrap><table-wrap id="T4" position="float"><label>Table 4</label><caption><p>Two by two comparison of OHRQoL scores.</p></caption><table frame="border" rules="all" width="100%"><thead><tr><th align="center" rowspan="1" colspan="1">Grade 3<break></break> Experimental</th><th valign="middle" align="center" rowspan="1" colspan="1">Grades 4 <break></break> Experimental</th><th valign="middle" align="center" rowspan="1" colspan="1">Grade 3
Control</th><th valign="middle" align="center" rowspan="1" colspan="1">Grades 4 <break></break>control</th><th align="center" rowspan="1" colspan="1">a & b</th><th align="center" rowspan="1" colspan="1">a & c</th><th align="center" rowspan="1" colspan="1">c & d</th><th align="center" rowspan="1" colspan="1">b & d</th></tr></thead><tbody><tr><td align="center" rowspan="1" colspan="1">1.12 ± 1.69<sup>a</sup></td><td align="center" rowspan="1" colspan="1">3.88 ± 3.22<sup>b</sup></td><td align="center" rowspan="1" colspan="1">8.25 ± 3.88<sup>c</sup></td><td align="center" rowspan="1" colspan="1">20.76 ± 6.64<sup>d</sup></td><td align="center" rowspan="1" colspan="1">0.001</td><td align="center" rowspan="1" colspan="1">0.001</td><td align="center" rowspan="1" colspan="1">0.001</td><td align="center" rowspan="1" colspan="1">0.001</td></tr></tbody></table></table-wrap></floats-group></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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