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The effect of chlorhexidine in reducing oral colonisation in geriatric patients: a randomised controlled trial

Identifieur interne : 000603 ( Pmc/Corpus ); précédent : 000602; suivant : 000604

The effect of chlorhexidine in reducing oral colonisation in geriatric patients: a randomised controlled trial

Auteurs : Sharifah Shafinaz Binti Sharif-Abdullah ; Mei Chan Chong ; Surat Singh Surindar-Kaur ; Shahrul Bahyah Kamaruzzaman ; Kwan Hoong Ng

Source :

Singapore Medical Journal [ 0037-5675 ] ; 2016.

RBID : PMC:4876416

Abstract

INTRODUCTION

Inadequate oral care has been implicated in the development of aspiration pneumonia in frail geriatric patients and is a major cause of mortality, due to the colonisation of microbes in vulnerable patients. This type of pneumonia has been associated with an increase in respiratory pathogens in the oral cavity. The aim of this study was to evaluate the effects of chlorhexidine compared to routine oral care in edentulous geriatric inpatients.

METHODS

A double-blind, parallel-group randomised controlled trial was carried out. The intervention group received oral care with chlorhexidine 0.2%, while the control group received routine oral care with thymol. Nurses provided oral care with assigned solutions of 20 mL once daily over seven days. Oral cavity assessment using the Brief Oral Health Status Examination form was performed before each oral care procedure. Data on medication received and the subsequent development of aspiration pneumonia was recorded. An oral swab was performed on Day 7 to obtain specimens to test for colonisation.

RESULTS

The final sample consisted of 35 (control) and 43 (intervention) patients. Chlorhexidine was effective in reducing oral colonisation compared to routine oral care with thymol (p < 0.001). The risk of oral bacterial colonisation was nearly three times higher in the thymol group compared to the chlorhexidine group.

CONCLUSION

The use of chlorhexidine 0.2% significantly reduced oral colonisation and is recommended as an easier and more cost-effective alternative for oral hygiene.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876416

DOI: 10.11622/smedj.2016091
PubMed: 27211885
PubMed Central: 4876416

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PMC:4876416

Le document en format XML

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<author><name sortKey="Sharif Abdullah, Sharifah Shafinaz Binti" sort="Sharif Abdullah, Sharifah Shafinaz Binti" uniqKey="Sharif Abdullah S" first="Sharifah Shafinaz Binti" last="Sharif-Abdullah">Sharifah Shafinaz Binti Sharif-Abdullah</name>
<affiliation><nlm:aff id="aff1">Department of Nursing Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2">Department of Nursing, Faculty of Health Science, Universiti Teknologi MARA, Puncak Alam Campus, Selangor, Malaysia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chong, Mei Chan" sort="Chong, Mei Chan" uniqKey="Chong M" first="Mei Chan" last="Chong">Mei Chan Chong</name>
<affiliation><nlm:aff id="aff1">Department of Nursing Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Surindar Kaur, Surat Singh" sort="Surindar Kaur, Surat Singh" uniqKey="Surindar Kaur S" first="Surat Singh" last="Surindar-Kaur">Surat Singh Surindar-Kaur</name>
<affiliation><nlm:aff id="aff1">Department of Nursing Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kamaruzzaman, Shahrul Bahyah" sort="Kamaruzzaman, Shahrul Bahyah" uniqKey="Kamaruzzaman S" first="Shahrul Bahyah" last="Kamaruzzaman">Shahrul Bahyah Kamaruzzaman</name>
<affiliation><nlm:aff id="aff3">Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ng, Kwan Hoong" sort="Ng, Kwan Hoong" uniqKey="Ng K" first="Kwan Hoong" last="Ng">Kwan Hoong Ng</name>
<affiliation><nlm:aff id="aff4">Department of Biomedical Imaging & University of Malaya Research Imaging Centre, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The effect of chlorhexidine in reducing oral colonisation in geriatric patients: a randomised controlled trial</title>
<author><name sortKey="Sharif Abdullah, Sharifah Shafinaz Binti" sort="Sharif Abdullah, Sharifah Shafinaz Binti" uniqKey="Sharif Abdullah S" first="Sharifah Shafinaz Binti" last="Sharif-Abdullah">Sharifah Shafinaz Binti Sharif-Abdullah</name>
<affiliation><nlm:aff id="aff1">Department of Nursing Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff2">Department of Nursing, Faculty of Health Science, Universiti Teknologi MARA, Puncak Alam Campus, Selangor, Malaysia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Chong, Mei Chan" sort="Chong, Mei Chan" uniqKey="Chong M" first="Mei Chan" last="Chong">Mei Chan Chong</name>
<affiliation><nlm:aff id="aff1">Department of Nursing Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Surindar Kaur, Surat Singh" sort="Surindar Kaur, Surat Singh" uniqKey="Surindar Kaur S" first="Surat Singh" last="Surindar-Kaur">Surat Singh Surindar-Kaur</name>
<affiliation><nlm:aff id="aff1">Department of Nursing Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kamaruzzaman, Shahrul Bahyah" sort="Kamaruzzaman, Shahrul Bahyah" uniqKey="Kamaruzzaman S" first="Shahrul Bahyah" last="Kamaruzzaman">Shahrul Bahyah Kamaruzzaman</name>
<affiliation><nlm:aff id="aff3">Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ng, Kwan Hoong" sort="Ng, Kwan Hoong" uniqKey="Ng K" first="Kwan Hoong" last="Ng">Kwan Hoong Ng</name>
<affiliation><nlm:aff id="aff4">Department of Biomedical Imaging & University of Malaya Research Imaging Centre, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Singapore Medical Journal</title>
<idno type="ISSN">0037-5675</idno>
<imprint><date when="2016">2016</date>
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<front><div type="abstract" xml:lang="en"><sec id="st1"><title>INTRODUCTION</title>
<p>Inadequate oral care has been implicated in the development of aspiration pneumonia in frail geriatric patients and is a major cause of mortality, due to the colonisation of microbes in vulnerable patients. This type of pneumonia has been associated with an increase in respiratory pathogens in the oral cavity. The aim of this study was to evaluate the effects of chlorhexidine compared to routine oral care in edentulous geriatric inpatients.</p>
</sec>
<sec id="st2"><title>METHODS</title>
<p>A double-blind, parallel-group randomised controlled trial was carried out. The intervention group received oral care with chlorhexidine 0.2%, while the control group received routine oral care with thymol. Nurses provided oral care with assigned solutions of 20 mL once daily over seven days. Oral cavity assessment using the Brief Oral Health Status Examination form was performed before each oral care procedure. Data on medication received and the subsequent development of aspiration pneumonia was recorded. An oral swab was performed on Day 7 to obtain specimens to test for colonisation.</p>
</sec>
<sec id="st3"><title>RESULTS</title>
<p>The final sample consisted of 35 (control) and 43 (intervention) patients. Chlorhexidine was effective in reducing oral colonisation compared to routine oral care with thymol (p < 0.001). The risk of oral bacterial colonisation was nearly three times higher in the thymol group compared to the chlorhexidine group.</p>
</sec>
<sec id="st4"><title>CONCLUSION</title>
<p>The use of chlorhexidine 0.2% significantly reduced oral colonisation and is recommended as an easier and more cost-effective alternative for oral hygiene.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
  <front><journal-meta><journal-id journal-id-type="nlm-ta">Singapore Med J</journal-id>
<journal-id journal-id-type="iso-abbrev">Singapore Med J</journal-id>
<journal-title-group><journal-title>Singapore Medical Journal</journal-title>
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<issn pub-type="ppub">0037-5675</issn>
<publisher><publisher-name>Singapore Medical Association</publisher-name>
<publisher-loc>Singapore</publisher-loc>
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<article-meta><article-id pub-id-type="pmid">27211885</article-id>
<article-id pub-id-type="pmc">4876416</article-id>
<article-id pub-id-type="publisher-id">SMJ-57-262</article-id>
<article-id pub-id-type="doi">10.11622/smedj.2016091</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>The effect of chlorhexidine in reducing oral colonisation in geriatric patients: a randomised controlled trial</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Sharif-Abdullah</surname>
<given-names>Sharifah Shafinaz Binti</given-names>
</name>
<degrees>MNSc, BNSc</degrees>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="aff" rid="aff2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chong</surname>
<given-names>Mei Chan</given-names>
</name>
<degrees>Phd, MSC</degrees>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="corresp" rid="cor1"></xref>
</contrib>
<contrib contrib-type="author"><name><surname>Surindar-Kaur</surname>
<given-names>Surat Singh</given-names>
</name>
<degrees>MNSc, BNSc</degrees>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kamaruzzaman</surname>
<given-names>Shahrul Bahyah</given-names>
</name>
<degrees>PhD, MRCP</degrees>
<xref ref-type="aff" rid="aff3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ng</surname>
<given-names>Kwan Hoong</given-names>
</name>
<degrees>PhD, DABMP</degrees>
<xref ref-type="aff" rid="aff4">4</xref>
</contrib>
</contrib-group>
<aff id="aff1"><label>1</label>
Department of Nursing Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</aff>
<aff id="aff2"><label>2</label>
Department of Nursing, Faculty of Health Science, Universiti Teknologi MARA, Puncak Alam Campus, Selangor, Malaysia</aff>
<aff id="aff3"><label>3</label>
Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</aff>
<aff id="aff4"><label>4</label>
Department of Biomedical Imaging & University of Malaya Research Imaging Centre, University of Malaya, Kuala Lumpur, Malaysia</aff>
<author-notes><corresp id="cor1"><bold>Correspondence:</bold>
 Dr Mei Chan Chong, Lecturer, Department of Nursing Science, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. <email xlink:href="mcchong@um.edu.my">mcchong@um.edu.my</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><month>5</month>
<year>2016</year>
</pub-date>
<volume>57</volume>
<issue>5</issue>
<fpage>262</fpage>
<lpage>266</lpage>
<permissions><copyright-statement>Copyright: © Singapore Medical Association</copyright-statement>
<copyright-year>2016</copyright-year>
</permissions>
<abstract><sec id="st1"><title>INTRODUCTION</title>
<p>Inadequate oral care has been implicated in the development of aspiration pneumonia in frail geriatric patients and is a major cause of mortality, due to the colonisation of microbes in vulnerable patients. This type of pneumonia has been associated with an increase in respiratory pathogens in the oral cavity. The aim of this study was to evaluate the effects of chlorhexidine compared to routine oral care in edentulous geriatric inpatients.</p>
</sec>
<sec id="st2"><title>METHODS</title>
<p>A double-blind, parallel-group randomised controlled trial was carried out. The intervention group received oral care with chlorhexidine 0.2%, while the control group received routine oral care with thymol. Nurses provided oral care with assigned solutions of 20 mL once daily over seven days. Oral cavity assessment using the Brief Oral Health Status Examination form was performed before each oral care procedure. Data on medication received and the subsequent development of aspiration pneumonia was recorded. An oral swab was performed on Day 7 to obtain specimens to test for colonisation.</p>
</sec>
<sec id="st3"><title>RESULTS</title>
<p>The final sample consisted of 35 (control) and 43 (intervention) patients. Chlorhexidine was effective in reducing oral colonisation compared to routine oral care with thymol (p < 0.001). The risk of oral bacterial colonisation was nearly three times higher in the thymol group compared to the chlorhexidine group.</p>
</sec>
<sec id="st4"><title>CONCLUSION</title>
<p>The use of chlorhexidine 0.2% significantly reduced oral colonisation and is recommended as an easier and more cost-effective alternative for oral hygiene.</p>
</sec>
</abstract>
<kwd-group><kwd><italic>aspiration</italic>
</kwd>
<kwd><italic>chlorhexidine</italic>
</kwd>
<kwd><italic>geriatrics</italic>
</kwd>
<kwd><italic>oral</italic>
</kwd>
<kwd><italic>pneumonia</italic>
</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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The effect of chlorhexidine in reducing oral colonisation in geriatric patients: a randomised controlled trial

The effect of chlorhexidine in reducing oral colonisation in geriatric patients: a randomised controlled trial

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Abstract

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