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<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Effect of Platelet Rich Fibrin (PRF) on Peri-implant Soft Tissue and Crestal Bone in One-Stage Implant Placement: A Randomized Controlled Trial</title>
<author>
<name sortKey="Boora, Priyanka" sort="Boora, Priyanka" uniqKey="Boora P" first="Priyanka" last="Boora">Priyanka Boora</name>
<affiliation>
<nlm:aff id="aff1"> Post Graduate Student, Department of Prosthodontics,
<institution>Post Graduate Institute of Dental Sciences, Pt. B.D Sharma University of Health Sciences</institution>
, Rohtak, Haryana, India.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Rathee, Manu" sort="Rathee, Manu" uniqKey="Rathee M" first="Manu" last="Rathee">Manu Rathee</name>
<affiliation>
<nlm:aff id="aff2"> Senior Professor and Head, Department of Prosthodontics,
<institution>Post Graduate Institute of Dental Sciences, Pt. B.D Sharma University of Health Sciences</institution>
, Rohtak, Haryana, India.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Bhoria, Mohaneesh" sort="Bhoria, Mohaneesh" uniqKey="Bhoria M" first="Mohaneesh" last="Bhoria">Mohaneesh Bhoria</name>
<affiliation>
<nlm:aff id="aff3"> Demonstrator, Department of Prosthodontics,
<institution>Post Graduate Institute of Dental Sciences, Pt. B.D Sharma University of Health Sciences</institution>
,
<addr-line>Rohtak, Haryana, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PMC</idno>
<idno type="pmid">26023636</idno>
<idno type="pmc">4437152</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437152</idno>
<idno type="RBID">PMC:4437152</idno>
<idno type="doi">10.7860/JCDR/2015/12636.5788</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">000217</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000217</idno>
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<biblStruct>
<analytic>
<title xml:lang="en" level="a" type="main">Effect of Platelet Rich Fibrin (PRF) on Peri-implant Soft Tissue and Crestal Bone in One-Stage Implant Placement: A Randomized Controlled Trial</title>
<author>
<name sortKey="Boora, Priyanka" sort="Boora, Priyanka" uniqKey="Boora P" first="Priyanka" last="Boora">Priyanka Boora</name>
<affiliation>
<nlm:aff id="aff1"> Post Graduate Student, Department of Prosthodontics,
<institution>Post Graduate Institute of Dental Sciences, Pt. B.D Sharma University of Health Sciences</institution>
, Rohtak, Haryana, India.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Rathee, Manu" sort="Rathee, Manu" uniqKey="Rathee M" first="Manu" last="Rathee">Manu Rathee</name>
<affiliation>
<nlm:aff id="aff2"> Senior Professor and Head, Department of Prosthodontics,
<institution>Post Graduate Institute of Dental Sciences, Pt. B.D Sharma University of Health Sciences</institution>
, Rohtak, Haryana, India.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Bhoria, Mohaneesh" sort="Bhoria, Mohaneesh" uniqKey="Bhoria M" first="Mohaneesh" last="Bhoria">Mohaneesh Bhoria</name>
<affiliation>
<nlm:aff id="aff3"> Demonstrator, Department of Prosthodontics,
<institution>Post Graduate Institute of Dental Sciences, Pt. B.D Sharma University of Health Sciences</institution>
,
<addr-line>Rohtak, Haryana, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Journal of Clinical and Diagnostic Research : JCDR</title>
<idno type="ISSN">2249-782X</idno>
<idno type="eISSN">0973-709X</idno>
<imprint>
<date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
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<textClass></textClass>
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<front>
<div type="abstract" xml:lang="en">
<sec>
<title>Introduction</title>
<p>The viability of Platelet Rich Fibrin (PRF) on enhancement of osseous and associated tissue healing has been substantiated well in literature. However, paucity in the applicability of PRF to enhance peri-implant healing in oral region is not well-corroborated.</p>
</sec>
<sec>
<title>Purpose</title>
<p>This prospective study evaluated the effect of Platelet PRF on peri-implant tissue response following one-stage implant placement with non-functional immediate provisionalization in maxillary anterior region.</p>
</sec>
<sec>
<title>Materials and Methods</title>
<p>A Prospective, Randomized Controlled Trial (RCT) was conducted across 20 (15 male, 5 Female) systemically healthy subjects with maintainable oral hygiene. Subjects were broadly divided into two groups i.e. Study group (PRF group) and Control group (Non-PRF group). Twenty standard SLA- AB/AE (alumina oxide blasted/acid etched surface treated) tapered threaded dental implants were randomly placed with and without PRF and immediately provisionalized. The subjects were evaluated clinically and radiographically at baseline (at time of implant placement), one month and three month post-operatively for peri-implant soft tissue and crestal bone responses.</p>
</sec>
<sec>
<title>Results</title>
<p>At 3 months, all implants remained osseointegrated. The mean marginal bone changes were observed from baseline to 3 months in both groups with lesser changes observed in PRF Group. No significant differences in probing depth and bleeding on probing were noted during follow-up.</p>
</sec>
<sec>
<title>Conclusion</title>
<p>Within the limitations of this study, PRF could be considered as a healing biomaterial with potential beneficial effect on peri-implant tissue and can be used as a therapeutic adjuvant in clinical scenario of one stage, single tooth implant placement procedure in maxillary anterior region.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">J Clin Diagn Res</journal-id>
<journal-id journal-id-type="iso-abbrev">J Clin Diagn Res</journal-id>
<journal-id journal-id-type="hwp">Journal of Clinical and Diagnostic Research</journal-id>
<journal-id journal-id-type="publisher-id">JCDR</journal-id>
<journal-title-group>
<journal-title>Journal of Clinical and Diagnostic Research : JCDR</journal-title>
</journal-title-group>
<issn pub-type="ppub">2249-782X</issn>
<issn pub-type="epub">0973-709X</issn>
<publisher>
<publisher-name>JCDR Research and Publications (P) Limited</publisher-name>
<publisher-loc>Delhi, India</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">26023636</article-id>
<article-id pub-id-type="pmc">4437152</article-id>
<article-id pub-id-type="doi">10.7860/JCDR/2015/12636.5788</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Dentistry Section</subject>
<subj-group subj-group-type="heading">
<subject>Original Article</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Effect of Platelet Rich Fibrin (PRF) on Peri-implant Soft Tissue and Crestal Bone in One-Stage Implant Placement: A Randomized Controlled Trial</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Boora</surname>
<given-names>Priyanka</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Rathee</surname>
<given-names>Manu</given-names>
</name>
<xref ref-type="aff" rid="aff2">2</xref>
<xref ref-type="corresp" rid="cor1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bhoria</surname>
<given-names>Mohaneesh</given-names>
</name>
<xref ref-type="aff" rid="aff3">3</xref>
</contrib>
</contrib-group>
<aff id="aff1">
<label>1</label>
Post Graduate Student, Department of Prosthodontics,
<institution>Post Graduate Institute of Dental Sciences, Pt. B.D Sharma University of Health Sciences</institution>
, Rohtak, Haryana, India.</aff>
<aff id="aff2">
<label>2</label>
Senior Professor and Head, Department of Prosthodontics,
<institution>Post Graduate Institute of Dental Sciences, Pt. B.D Sharma University of Health Sciences</institution>
, Rohtak, Haryana, India.</aff>
<aff id="aff3">
<label>3</label>
Demonstrator, Department of Prosthodontics,
<institution>Post Graduate Institute of Dental Sciences, Pt. B.D Sharma University of Health Sciences</institution>
,
<addr-line>Rohtak, Haryana, India</addr-line>
.</aff>
<author-notes>
<corresp id="cor1">NAME, ADDRESS, E-MAIL ID OF THE CORRESPONDING AUTHOR: Dr. Manu Rathee, Senior Professor and Head, Department of Prosthodontics, Post Graduate Institute of Dental Sciences, Pt. B.D Sharma University of Health Sciences, Rohtak, Haryana-124001, India. E-mail:
<email>ratheemanu@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>4</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="epub">
<day>01</day>
<month>4</month>
<year>2015</year>
</pub-date>
<volume>9</volume>
<issue>4</issue>
<fpage>ZC18</fpage>
<lpage>ZC21</lpage>
<history>
<date date-type="received">
<day>22</day>
<month>12</month>
<year>2014</year>
</date>
<date date-type="rev-request">
<day>19</day>
<month>1</month>
<year>2015</year>
</date>
<date date-type="accepted">
<day>13</day>
<month>2</month>
<year>2015</year>
</date>
</history>
<permissions>
<copyright-statement>© 2015 Journal of Clinical and Diagnostic Research</copyright-statement>
<copyright-year>2015</copyright-year>
</permissions>
<abstract>
<sec>
<title>Introduction</title>
<p>The viability of Platelet Rich Fibrin (PRF) on enhancement of osseous and associated tissue healing has been substantiated well in literature. However, paucity in the applicability of PRF to enhance peri-implant healing in oral region is not well-corroborated.</p>
</sec>
<sec>
<title>Purpose</title>
<p>This prospective study evaluated the effect of Platelet PRF on peri-implant tissue response following one-stage implant placement with non-functional immediate provisionalization in maxillary anterior region.</p>
</sec>
<sec>
<title>Materials and Methods</title>
<p>A Prospective, Randomized Controlled Trial (RCT) was conducted across 20 (15 male, 5 Female) systemically healthy subjects with maintainable oral hygiene. Subjects were broadly divided into two groups i.e. Study group (PRF group) and Control group (Non-PRF group). Twenty standard SLA- AB/AE (alumina oxide blasted/acid etched surface treated) tapered threaded dental implants were randomly placed with and without PRF and immediately provisionalized. The subjects were evaluated clinically and radiographically at baseline (at time of implant placement), one month and three month post-operatively for peri-implant soft tissue and crestal bone responses.</p>
</sec>
<sec>
<title>Results</title>
<p>At 3 months, all implants remained osseointegrated. The mean marginal bone changes were observed from baseline to 3 months in both groups with lesser changes observed in PRF Group. No significant differences in probing depth and bleeding on probing were noted during follow-up.</p>
</sec>
<sec>
<title>Conclusion</title>
<p>Within the limitations of this study, PRF could be considered as a healing biomaterial with potential beneficial effect on peri-implant tissue and can be used as a therapeutic adjuvant in clinical scenario of one stage, single tooth implant placement procedure in maxillary anterior region.</p>
</sec>
</abstract>
<kwd-group>
<kwd>Dental Implants</kwd>
<kwd>Fibrin membrane</kwd>
<kwd>Immediate loading</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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