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<title xml:lang="en">Guided Bone Regeneration of an Atrophic Mandible with a Heterologous Bone Block</title>
<author>
<name sortKey="Di Stefano, Danilo Alessio" sort="Di Stefano, Danilo Alessio" uniqKey="Di Stefano D" first="Danilo Alessio" last="Di Stefano">Danilo Alessio Di Stefano</name>
<affiliation>
<nlm:aff id="AF140398cr-1">
<institution>Department of Dentistry, Vita e Salute San Raffaele University, Milan, Italy</institution>
</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="AF140398cr-2">
<institution>Dentalnarco Odontoiatric Center, Trezzano Sul Naviglio, Italy</institution>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Greco, Gian Battista" sort="Greco, Gian Battista" uniqKey="Greco G" first="Gian Battista" last="Greco">Gian Battista Greco</name>
<affiliation>
<nlm:aff id="AF140398cr-2">
<institution>Dentalnarco Odontoiatric Center, Trezzano Sul Naviglio, Italy</institution>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Riboli, Francesco" sort="Riboli, Francesco" uniqKey="Riboli F" first="Francesco" last="Riboli">Francesco Riboli</name>
<affiliation>
<nlm:aff id="AF140398cr-2">
<institution>Dentalnarco Odontoiatric Center, Trezzano Sul Naviglio, Italy</institution>
</nlm:aff>
</affiliation>
</author>
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<idno type="wicri:source">PMC</idno>
<idno type="pmid">26889354</idno>
<idno type="pmc">4755768</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755768</idno>
<idno type="RBID">PMC:4755768</idno>
<idno type="doi">10.1055/s-0035-1551544</idno>
<date when="2015">2015</date>
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<title xml:lang="en" level="a" type="main">Guided Bone Regeneration of an Atrophic Mandible with a Heterologous Bone Block</title>
<author>
<name sortKey="Di Stefano, Danilo Alessio" sort="Di Stefano, Danilo Alessio" uniqKey="Di Stefano D" first="Danilo Alessio" last="Di Stefano">Danilo Alessio Di Stefano</name>
<affiliation>
<nlm:aff id="AF140398cr-1">
<institution>Department of Dentistry, Vita e Salute San Raffaele University, Milan, Italy</institution>
</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="AF140398cr-2">
<institution>Dentalnarco Odontoiatric Center, Trezzano Sul Naviglio, Italy</institution>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Greco, Gian Battista" sort="Greco, Gian Battista" uniqKey="Greco G" first="Gian Battista" last="Greco">Gian Battista Greco</name>
<affiliation>
<nlm:aff id="AF140398cr-2">
<institution>Dentalnarco Odontoiatric Center, Trezzano Sul Naviglio, Italy</institution>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Riboli, Francesco" sort="Riboli, Francesco" uniqKey="Riboli F" first="Francesco" last="Riboli">Francesco Riboli</name>
<affiliation>
<nlm:aff id="AF140398cr-2">
<institution>Dentalnarco Odontoiatric Center, Trezzano Sul Naviglio, Italy</institution>
</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Craniomaxillofacial Trauma & Reconstruction</title>
<idno type="ISSN">1943-3875</idno>
<idno type="eISSN">1943-3883</idno>
<imprint>
<date when="2015">2015</date>
</imprint>
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<div type="abstract" xml:lang="en">
<p>The aim of this work was to test the effectiveness of using enzymatically deantigenated equine bone block as a scaffold for guided bone regeneration (GBR) during a horizontal augmentation of the lower jaw. A partially edentulous atrophic mandible was augmented using an equine-derived block with an expanded polytetrafluoroethylene membrane. After 8.5 months, two bone core samples were collected at the augmentation site, and implants were placed. A definitive prosthesis delivered 6 months after implant placement provided excellent functional and aesthetic rehabilitation throughout the follow-up period. Histological and histomorphometrical analysis of the biopsies showed newly formed bone to be present and the residual biomaterial was still undergoing remodeling. Comparison of cone beam computed tomography scans taken before augmentation and 26 months later showed maintenance of ridge width and possible corticalization of the vestibular augmented ridge side. The equine-derived bone block placed in accordance with GBR principles provided a successful clinical, radiographic, and histological outcome.</p>
</div>
</front>
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<pmc article-type="case-report">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Craniomaxillofac Trauma Reconstr</journal-id>
<journal-id journal-id-type="iso-abbrev">Craniomaxillofac Trauma Reconstr</journal-id>
<journal-id journal-id-type="doi">10.1055/s-00000151</journal-id>
<journal-title-group>
<journal-title>Craniomaxillofacial Trauma & Reconstruction</journal-title>
</journal-title-group>
<issn pub-type="ppub">1943-3875</issn>
<issn pub-type="epub">1943-3883</issn>
<publisher>
<publisher-name>Thieme Medical Publishers</publisher-name>
<publisher-loc>333 Seventh Avenue, New York, NY 10001, USA.</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">26889354</article-id>
<article-id pub-id-type="pmc">4755768</article-id>
<article-id pub-id-type="doi">10.1055/s-0035-1551544</article-id>
<article-id pub-id-type="publisher-id">140398cr</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Guided Bone Regeneration of an Atrophic Mandible with a Heterologous Bone Block</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Di Stefano</surname>
<given-names>Danilo Alessio</given-names>
</name>
<degrees>DDS</degrees>
<xref rid="AF140398cr-1" ref-type="aff">1</xref>
<xref rid="AF140398cr-2" ref-type="aff">2</xref>
<xref rid="CO140398cr-1" ref-type="author-notes"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Greco</surname>
<given-names>Gian Battista</given-names>
</name>
<degrees>DDS</degrees>
<xref rid="AF140398cr-2" ref-type="aff">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Riboli</surname>
<given-names>Francesco</given-names>
</name>
<degrees>DDS</degrees>
<xref rid="AF140398cr-2" ref-type="aff">2</xref>
</contrib>
</contrib-group>
<aff id="AF140398cr-1">
<label>1</label>
<institution>Department of Dentistry, Vita e Salute San Raffaele University, Milan, Italy</institution>
</aff>
<aff id="AF140398cr-2">
<label>2</label>
<institution>Dentalnarco Odontoiatric Center, Trezzano Sul Naviglio, Italy</institution>
</aff>
<author-notes>
<corresp id="CO140398cr-1">
<bold>Address for correspondence </bold>
Danilo Alessio Di Stefano, DDS
<institution>Department of Dentistry</institution>
<institution>Vita e Salute San Raffaele University</institution>
<addr-line>Via Matteo Civitali 40, 20148 Milan</addr-line>
<country>Italy</country>
<email>distefano@centrocivitali.it</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>01</day>
<month>5</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="ppub">
<month>3</month>
<year>2016</year>
</pub-date>
<volume>9</volume>
<issue>1</issue>
<fpage>88</fpage>
<lpage>93</lpage>
<history>
<date date-type="received">
<day>16</day>
<month>9</month>
<year>2014</year>
</date>
<date date-type="accepted">
<day>12</day>
<month>1</month>
<year>2015</year>
</date>
</history>
<permissions>
<copyright-statement>© Thieme Medical Publishers</copyright-statement>
</permissions>
<abstract>
<p>The aim of this work was to test the effectiveness of using enzymatically deantigenated equine bone block as a scaffold for guided bone regeneration (GBR) during a horizontal augmentation of the lower jaw. A partially edentulous atrophic mandible was augmented using an equine-derived block with an expanded polytetrafluoroethylene membrane. After 8.5 months, two bone core samples were collected at the augmentation site, and implants were placed. A definitive prosthesis delivered 6 months after implant placement provided excellent functional and aesthetic rehabilitation throughout the follow-up period. Histological and histomorphometrical analysis of the biopsies showed newly formed bone to be present and the residual biomaterial was still undergoing remodeling. Comparison of cone beam computed tomography scans taken before augmentation and 26 months later showed maintenance of ridge width and possible corticalization of the vestibular augmented ridge side. The equine-derived bone block placed in accordance with GBR principles provided a successful clinical, radiographic, and histological outcome.</p>
</abstract>
<kwd-group xml:lang="en">
<title>Keywords</title>
<kwd>equine bone</kwd>
<kwd>guided bone regeneration</kwd>
<kwd>heterologous bone</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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