Relationship of tooth loss to mild memory impairment and cognitive impairment: findings from the fujiwara-kyo study
Identifieur interne : 002321 ( Pmc/Checkpoint ); précédent : 002320; suivant : 002322Relationship of tooth loss to mild memory impairment and cognitive impairment: findings from the fujiwara-kyo study
Auteurs : Nozomi Okamoto [Japon] ; Masayuki Morikawa [Japon] ; Kensuke Okamoto [Japon] ; Noboru Habu [Japon] ; Junko Iwamoto [Japon] ; Kimiko Tomioka [Japon] ; Keigo Saeki [Japon] ; Motokazu Yanagi [Japon] ; Nobuko Amano [Japon] ; Norio Kurumatani [Japon]Source :
- Behavioral and Brain Functions : BBF [ 1744-9081 ] ; 2010.
Abstract
This cross-sectional study investigated the relationship between the number of remaining teeth to mild memory impairment (MMI), which is a preclinical stage of dementia, and to cognitive impairment.
The subjects were aged 65 years or older and were grouped according to their score for the Mini-Mental State Examination (MMSE), the three-word delayed recall test in the MMSE, and the Geriatric Depression Scale into the control group (n = 3,696), the MMI group (n = 121), and the low MMSE score (23 or lower) group (n = 214). We collected data on the number of remaining teeth, the length of the edentulous period, health-related lifestyle, medical history, blood pressure, height, and body weight. Fasting venous blood samples were also obtained.
Multiple logistic regression analysis, adjusted for depressive symptoms, age, sex, length of education, and other explanatory variables, revealed that the odds ratios of 0-10 remaining teeth to 22-32 remaining teeth were 1.679 (95% CI 1.073-2.627) for MMI and 2.177 (95% CI 1.510-3.140) for a low MMSE score. A significant relationship was also found between the length of the edentulous period and the risk of a low MMSE score (odds ratio 3.102, 95% CI 1.432-6.720) (15 years or more/less than 15 years).
Our findings suggest that tooth loss is associated with cognitive function.
Url:
DOI: 10.1186/1744-9081-6-77
PubMed: 21194415
PubMed Central: 3024962
Affiliations:
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xml:lang="fr">Japon</country><wicri:regionArea>Department of Indoor Environmental Medicine, Nara Medical University</wicri:regionArea><wicri:noRegion>Nara Medical University</wicri:noRegion></affiliation></author><author><name sortKey="Tomioka, Kimiko" sort="Tomioka, Kimiko" uniqKey="Tomioka K" first="Kimiko" last="Tomioka">Kimiko Tomioka</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Community Health and Epidemiology, Nara Medical University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Community Health and Epidemiology, Nara Medical University</wicri:regionArea><wicri:noRegion>Nara Medical University</wicri:noRegion></affiliation></author><author><name sortKey="Saeki, Keigo" sort="Saeki, Keigo" uniqKey="Saeki K" first="Keigo" last="Saeki">Keigo Saeki</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Community Health and Epidemiology, Nara Medical University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Community Health and Epidemiology, Nara Medical University</wicri:regionArea><wicri:noRegion>Nara Medical University</wicri:noRegion></affiliation></author><author><name sortKey="Yanagi, Motokazu" sort="Yanagi, Motokazu" uniqKey="Yanagi M" first="Motokazu" last="Yanagi">Motokazu Yanagi</name><affiliation wicri:level="1"><nlm:aff id="I7">Department of Food and Nutrition, Tezukayama University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Food and Nutrition, Tezukayama University</wicri:regionArea><wicri:noRegion>Tezukayama University</wicri:noRegion></affiliation></author><author><name sortKey="Amano, Nobuko" sort="Amano, Nobuko" uniqKey="Amano N" first="Nobuko" last="Amano">Nobuko Amano</name><affiliation wicri:level="1"><nlm:aff id="I7">Department of Food and Nutrition, Tezukayama University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Food and Nutrition, Tezukayama University</wicri:regionArea><wicri:noRegion>Tezukayama University</wicri:noRegion></affiliation></author><author><name sortKey="Kurumatani, Norio" sort="Kurumatani, Norio" uniqKey="Kurumatani N" first="Norio" last="Kurumatani">Norio Kurumatani</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Community Health and Epidemiology, Nara Medical University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Community Health and Epidemiology, Nara Medical University</wicri:regionArea><wicri:noRegion>Nara Medical University</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21194415</idno><idno type="pmc">3024962</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024962</idno><idno type="RBID">PMC:3024962</idno><idno type="doi">10.1186/1744-9081-6-77</idno><date when="2010">2010</date><idno 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Epidemiology, Nara Medical University</wicri:regionArea><wicri:noRegion>Nara Medical University</wicri:noRegion></affiliation></author><author><name sortKey="Morikawa, Masayuki" sort="Morikawa, Masayuki" uniqKey="Morikawa M" first="Masayuki" last="Morikawa">Masayuki Morikawa</name><affiliation wicri:level="1"><nlm:aff id="I2">Sakai City Mental Health Center, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Sakai City Mental Health Center</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="I3">Department of Psychiatry, Nara Medical University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Psychiatry, Nara Medical University</wicri:regionArea><wicri:noRegion>Nara Medical University</wicri:noRegion></affiliation></author><author><name sortKey="Okamoto, Kensuke" sort="Okamoto, Kensuke" uniqKey="Okamoto K" first="Kensuke" last="Okamoto">Kensuke Okamoto</name><affiliation wicri:level="1"><nlm:aff id="I4">Department of Oral and Maxillofacial Surgery, Nara Kasuga Hospital, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Oral and Maxillofacial Surgery, Nara Kasuga Hospital</wicri:regionArea><wicri:noRegion>Nara Kasuga Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I5">Department of Oral and Maxillofacial Surgery, Nara Medical University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Oral and Maxillofacial Surgery, Nara Medical University</wicri:regionArea><wicri:noRegion>Nara Medical University</wicri:noRegion></affiliation></author><author><name sortKey="Habu, Noboru" sort="Habu, Noboru" uniqKey="Habu N" first="Noboru" last="Habu">Noboru Habu</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Community Health and Epidemiology, Nara Medical University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Community Health and Epidemiology, Nara Medical University</wicri:regionArea><wicri:noRegion>Nara Medical University</wicri:noRegion></affiliation></author><author><name sortKey="Iwamoto, Junko" sort="Iwamoto, Junko" uniqKey="Iwamoto J" first="Junko" last="Iwamoto">Junko Iwamoto</name><affiliation wicri:level="1"><nlm:aff id="I6">Department of Indoor Environmental Medicine, Nara Medical University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Indoor Environmental Medicine, Nara Medical University</wicri:regionArea><wicri:noRegion>Nara Medical University</wicri:noRegion></affiliation></author><author><name sortKey="Tomioka, Kimiko" sort="Tomioka, Kimiko" uniqKey="Tomioka K" first="Kimiko" last="Tomioka">Kimiko Tomioka</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Community Health and Epidemiology, Nara Medical University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Community Health and Epidemiology, Nara Medical University</wicri:regionArea><wicri:noRegion>Nara Medical University</wicri:noRegion></affiliation></author><author><name sortKey="Saeki, Keigo" sort="Saeki, Keigo" uniqKey="Saeki K" first="Keigo" last="Saeki">Keigo Saeki</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Community Health and Epidemiology, Nara Medical University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Community Health and Epidemiology, Nara Medical University</wicri:regionArea><wicri:noRegion>Nara Medical University</wicri:noRegion></affiliation></author><author><name sortKey="Yanagi, Motokazu" sort="Yanagi, Motokazu" uniqKey="Yanagi M" first="Motokazu" last="Yanagi">Motokazu Yanagi</name><affiliation wicri:level="1"><nlm:aff id="I7">Department of Food and Nutrition, Tezukayama University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Food and Nutrition, Tezukayama University</wicri:regionArea><wicri:noRegion>Tezukayama University</wicri:noRegion></affiliation></author><author><name sortKey="Amano, Nobuko" sort="Amano, Nobuko" uniqKey="Amano N" first="Nobuko" last="Amano">Nobuko Amano</name><affiliation wicri:level="1"><nlm:aff id="I7">Department of Food and Nutrition, Tezukayama University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Food and Nutrition, Tezukayama University</wicri:regionArea><wicri:noRegion>Tezukayama University</wicri:noRegion></affiliation></author><author><name sortKey="Kurumatani, Norio" sort="Kurumatani, Norio" uniqKey="Kurumatani N" first="Norio" last="Kurumatani">Norio Kurumatani</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Community Health and Epidemiology, Nara Medical University, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Community Health and Epidemiology, Nara Medical University</wicri:regionArea><wicri:noRegion>Nara Medical University</wicri:noRegion></affiliation></author></analytic><series><title level="j">Behavioral and Brain Functions : BBF</title><idno type="eISSN">1744-9081</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>This cross-sectional study investigated the relationship between the number of remaining teeth to mild memory impairment (MMI), which is a preclinical stage of dementia, and to cognitive impairment.</p></sec><sec><title>Methods</title><p>The subjects were aged 65 years or older and were grouped according to their score for the Mini-Mental State Examination (MMSE), the three-word delayed recall test in the MMSE, and the Geriatric Depression Scale into the control group (n = 3,696), the MMI group (n = 121), and the low MMSE score (23 or lower) group (n = 214). We collected data on the number of remaining teeth, the length of the edentulous period, health-related lifestyle, medical history, blood pressure, height, and body weight. Fasting venous blood samples were also obtained.</p></sec><sec><title>Results</title><p>Multiple logistic regression analysis, adjusted for depressive symptoms, age, sex, length of education, and other explanatory variables, revealed that the odds ratios of 0-10 remaining teeth to 22-32 remaining teeth were 1.679 (95% CI 1.073-2.627) for MMI and 2.177 (95% CI 1.510-3.140) for a low MMSE score. A significant relationship was also found between the length of the edentulous period and the risk of a low MMSE score (odds ratio 3.102, 95% CI 1.432-6.720) (15 years or more/less than 15 years).</p></sec><sec><title>Conclusions</title><p>Our findings suggest that tooth loss is associated with cognitive function.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Desvarieux, M" uniqKey="Desvarieux M">M Desvarieux</name></author><author><name sortKey="Demmer, Rt" uniqKey="Demmer R">RT Demmer</name></author><author><name sortKey="Rundek, T" uniqKey="Rundek T">T Rundek</name></author><author><name sortKey="Boden Albala, B" uniqKey="Boden Albala B">B Boden-Albala</name></author><author><name sortKey="Jacobs, Dr" uniqKey="Jacobs D">DR Jacobs</name></author><author><name sortKey="Papapanou, Pn" uniqKey="Papapanou P">PN Papapanou</name></author><author><name sortKey="Sacco, Rl" uniqKey="Sacco R">RL Sacco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Humphrey, Ll" uniqKey="Humphrey L">LL Humphrey</name></author><author><name sortKey="Fu, R" uniqKey="Fu R">R Fu</name></author><author><name sortKey="Buckley, Di" uniqKey="Buckley D">DI Buckley</name></author><author><name sortKey="Freeman, M" uniqKey="Freeman M">M Freeman</name></author><author><name sortKey="Helfand, M" uniqKey="Helfand M">M Helfand</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gatz, M" uniqKey="Gatz M">M Gatz</name></author><author><name sortKey="Mortimer, Ja" uniqKey="Mortimer J">JA Mortimer</name></author><author><name sortKey="Fratiglioni, L" uniqKey="Fratiglioni L">L Fratiglioni</name></author><author><name sortKey="Johansson, B" uniqKey="Johansson B">B Johansson</name></author><author><name sortKey="Berg, S" uniqKey="Berg S">S Berg</name></author><author><name sortKey="Reynolds, Ca" uniqKey="Reynolds C">CA Reynolds</name></author><author><name sortKey="Pedersen, Nl" uniqKey="Pedersen N">NL Pedersen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stein, Ps" uniqKey="Stein P">PS Stein</name></author><author><name sortKey="Desrosiers, M" uniqKey="Desrosiers M">M Desrosiers</name></author><author><name sortKey="Donegan, Sj" uniqKey="Donegan S">SJ Donegan</name></author><author><name sortKey="Yepes, Jf" uniqKey="Yepes J">JF Yepes</name></author><author><name sortKey="Kryscio, Rj" uniqKey="Kryscio R">RJ Kryscio</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chalmers, Jm" uniqKey="Chalmers J">JM Chalmers</name></author><author><name sortKey="Charter, Kd" uniqKey="Charter K">KD Charter</name></author><author><name sortKey="Spencer, Aj" uniqKey="Spencer A">AJ Spencer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Jm" uniqKey="Kim J">JM Kim</name></author><author><name sortKey="Stewart, R" uniqKey="Stewart R">R Stewart</name></author><author><name sortKey="Prince, M" uniqKey="Prince M">M Prince</name></author><author><name sortKey="Kim, Sw" uniqKey="Kim S">SW Kim</name></author><author><name sortKey="Yang, Sj" uniqKey="Yang S">SJ Yang</name></author><author><name sortKey="Shin, Is" uniqKey="Shin I">IS Shin</name></author><author><name sortKey="Yoon, Js" uniqKey="Yoon J">JS Yoon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yamazaki, K" uniqKey="Yamazaki K">K Yamazaki</name></author><author><name sortKey="Wakabayashi, N" uniqKey="Wakabayashi N">N Wakabayashi</name></author><author><name sortKey="Kobayashi, T" uniqKey="Kobayashi T">T Kobayashi</name></author><author><name sortKey="Suzuki, T" uniqKey="Suzuki T">T Suzuki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Makiura, T" uniqKey="Makiura T">T Makiura</name></author><author><name sortKey="Ikeda, Y" uniqKey="Ikeda Y">Y Ikeda</name></author><author><name sortKey="Hirai, T" uniqKey="Hirai T">T Hirai</name></author><author><name sortKey="Terasawa, H" uniqKey="Terasawa H">H Terasawa</name></author><author><name sortKey="Hamaue, N" uniqKey="Hamaue N">N Hamaue</name></author><author><name sortKey="Minami, M" uniqKey="Minami M">M Minami</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kamer, Ar" uniqKey="Kamer A">AR Kamer</name></author><author><name sortKey="Craig, Rg" uniqKey="Craig R">RG Craig</name></author><author><name sortKey="Dasanayake, Ap" uniqKey="Dasanayake A">AP Dasanayake</name></author><author><name sortKey="Brys, M" uniqKey="Brys M">M Brys</name></author><author><name sortKey="Glodzik Sobanska, L" uniqKey="Glodzik Sobanska L">L Glodzik-Sobanska</name></author><author><name sortKey="De Leon, Mj" uniqKey="De Leon M">MJ de Leon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Blasko, I" uniqKey="Blasko I">I Blasko</name></author><author><name sortKey="Grubeck Loebenstein, B" uniqKey="Grubeck Loebenstein B">B Grubeck-Loebenstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rogers, J" uniqKey="Rogers J">J Rogers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ishikawa, T" uniqKey="Ishikawa T">T Ishikawa</name></author><author><name sortKey="Ikeda, M" uniqKey="Ikeda M">M Ikeda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ishikawa, T" uniqKey="Ishikawa T">T Ishikawa</name></author><author><name sortKey="Ikeda, M" uniqKey="Ikeda M">M Ikeda</name></author><author><name sortKey="Matsumoto, N" uniqKey="Matsumoto N">N Matsumoto</name></author><author><name sortKey="Shigenobu, K" uniqKey="Shigenobu K">K Shigenobu</name></author><author><name sortKey="Brayne, C" uniqKey="Brayne C">C Brayne</name></author><author><name sortKey="Tanabe, H" uniqKey="Tanabe H">H Tanabe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Folstein, Mf" uniqKey="Folstein M">MF Folstein</name></author><author><name sortKey="Folstein, Se" uniqKey="Folstein S">SE Folstein</name></author><author><name sortKey="Mchugh, Pr" uniqKey="Mchugh P">PR Mchugh</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Ishizaki, J" uniqKey="Ishizaki J">J Ishizaki</name></author><author><name sortKey="Meguro, K" uniqKey="Meguro K">K Meguro</name></author><author><name sortKey="Ambo, H" uniqKey="Ambo H">H Ambo</name></author><author><name sortKey="Shimada, M" uniqKey="Shimada M">M Shimada</name></author><author><name sortKey="Yamaguchi, S" uniqKey="Yamaguchi S">S Yamaguchi</name></author><author><name sortKey="Hayasaka, C" uniqKey="Hayasaka C">C Hayasaka</name></author><author><name sortKey="Komatsu, H" uniqKey="Komatsu H">H Komatsu</name></author><author><name sortKey="Sekita, Y" uniqKey="Sekita Y">Y Sekita</name></author><author><name sortKey="Yamadori, A" uniqKey="Yamadori A">A Yamadori</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schreiner, As" uniqKey="Schreiner A">AS Schreiner</name></author><author><name sortKey="Hayakawa, H" uniqKey="Hayakawa H">H Hayakawa</name></author><author><name sortKey="Morimoto, T" uniqKey="Morimoto T">T Morimoto</name></author><author><name sortKey="Kakuma, T" uniqKey="Kakuma T">T Kakuma</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Mantel, N" uniqKey="Mantel N">N Mantel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Field, A" uniqKey="Field A">A Field</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stewart, R" uniqKey="Stewart R">R Stewart</name></author><author><name sortKey="Hirani, V" uniqKey="Hirani V">V Hirani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stewart, R" uniqKey="Stewart R">R Stewart</name></author><author><name sortKey="Sabbah, W" uniqKey="Sabbah W">W Sabbah</name></author><author><name sortKey="Tsakos, G" uniqKey="Tsakos G">G Tsakos</name></author><author><name sortKey="D Aiuto, F" uniqKey="D Aiuto F">F D'Aiuto</name></author><author><name sortKey="Watt, Rg" uniqKey="Watt R">RG Watt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meguro, K" uniqKey="Meguro K">K Meguro</name></author><author><name sortKey="Ishii, H" uniqKey="Ishii H">H Ishii</name></author><author><name sortKey="Yamaguchi, S" uniqKey="Yamaguchi S">S Yamaguchi</name></author><author><name sortKey="Ishizaki, J" uniqKey="Ishizaki J">J Ishizaki</name></author><author><name sortKey="Sato, M" uniqKey="Sato M">M Sato</name></author><author><name sortKey="Hashimoto, R" uniqKey="Hashimoto R">R Hashimoto</name></author><author><name sortKey="Meguro, M" uniqKey="Meguro M">M Meguro</name></author><author><name sortKey="Lee, E" uniqKey="Lee E">E Lee</name></author><author><name sortKey="Tanaka, Y" uniqKey="Tanaka Y">Y Tanaka</name></author><author><name sortKey="Kasuya, M" uniqKey="Kasuya M">M Kasuya</name></author><author><name sortKey="Sekita, Y" uniqKey="Sekita Y">Y Sekita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sasaki, M" uniqKey="Sasaki M">M Sasaki</name></author><author><name sortKey="Kodama, C" uniqKey="Kodama C">C Kodama</name></author><author><name sortKey="Hidaka, S" uniqKey="Hidaka S">S Hidaka</name></author><author><name sortKey="Yamashita, F" uniqKey="Yamashita F">F Yamashita</name></author><author><name sortKey="Kinoshita, T" uniqKey="Kinoshita T">T Kinoshita</name></author><author><name sortKey="Nemoto, K" uniqKey="Nemoto K">K Nemoto</name></author><author><name sortKey="Ikejima, C" uniqKey="Ikejima C">C Ikejima</name></author><author><name sortKey="Asada, T" uniqKey="Asada T">T Asada</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Petersen, Rc" uniqKey="Petersen R">RC Petersen</name></author><author><name sortKey="Smith, Ge" uniqKey="Smith G">GE Smith</name></author><author><name sortKey="Waring, Sc" uniqKey="Waring S">SC Waring</name></author><author><name sortKey="Ivnik, Rj" uniqKey="Ivnik R">RJ Ivnik</name></author><author><name sortKey="Tangalos, Eg" uniqKey="Tangalos E">EG Tangalos</name></author><author><name sortKey="Kokmen, E" uniqKey="Kokmen E">E Kokmen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schmidt, R" uniqKey="Schmidt R">R Schmidt</name></author><author><name sortKey="Schmidt, H" uniqKey="Schmidt H">H Schmidt</name></author><author><name sortKey="Curb, Jd" uniqKey="Curb J">JD Curb</name></author><author><name sortKey="Masaki, K" uniqKey="Masaki K">K Masaki</name></author><author><name sortKey="White, Lr" uniqKey="White L">LR White</name></author><author><name sortKey="Launer, Lj" uniqKey="Launer L">LJ Launer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Avlund, K" uniqKey="Avlund K">K Avlund</name></author><author><name sortKey="Holm Pedersen, P" uniqKey="Holm Pedersen P">P Holm-Pedersen</name></author><author><name sortKey="Morse, De" uniqKey="Morse D">DE Morse</name></author><author><name sortKey="Viitanen, M" uniqKey="Viitanen M">M Viitanen</name></author><author><name sortKey="Winblad, B" uniqKey="Winblad B">B Winblad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aida, J" uniqKey="Aida J">J Aida</name></author><author><name sortKey="Ando, Y" uniqKey="Ando Y">Y Ando</name></author><author><name sortKey="Akhter, R" uniqKey="Akhter R">R Akhter</name></author><author><name sortKey="Aoyama, H" uniqKey="Aoyama H">H Aoyama</name></author><author><name sortKey="Masui, M" uniqKey="Masui M">M Masui</name></author><author><name sortKey="Morita, M" uniqKey="Morita M">M Morita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Watts, A" uniqKey="Watts A">A Watts</name></author><author><name sortKey="Crimmins, Em" uniqKey="Crimmins E">EM Crimmins</name></author><author><name sortKey="Gatz, M" uniqKey="Gatz M">M Gatz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kornman, Ks" uniqKey="Kornman K">KS Kornman</name></author><author><name sortKey="Crane, A" uniqKey="Crane A">A Crane</name></author><author><name sortKey="Wang, H Y" uniqKey="Wang H">H-Y Wang</name></author><author><name sortKey="Di Giovine, Fs" uniqKey="Di Giovine F">FS di Giovine</name></author><author><name sortKey="Newman, Mg" uniqKey="Newman M">MG Newman</name></author><author><name sortKey="Pirk, Fw" uniqKey="Pirk F">FW Pirk</name></author><author><name sortKey="Wilson Jr, Tg" uniqKey="Wilson Jr T">TG Wilson Jr</name></author><author><name sortKey="Higginbottom, Fl" uniqKey="Higginbottom F">FL Higginbottom</name></author><author><name sortKey="Duff, Gw" uniqKey="Duff G">GW Duff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcgeer, Pl" uniqKey="Mcgeer P">PL McGeer</name></author><author><name sortKey="Mcgeer, Eg" uniqKey="Mcgeer E">EG McGeer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jacobs, R" uniqKey="Jacobs R">R Jacobs</name></author><author><name sortKey="Steenberghe, Dv" uniqKey="Steenberghe D">DV Steenberghe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kato, T" uniqKey="Kato T">T Kato</name></author><author><name sortKey="Usami, T" uniqKey="Usami T">T Usami</name></author><author><name sortKey="Noda, Y" uniqKey="Noda Y">Y Noda</name></author><author><name sortKey="Hasegawa, M" uniqKey="Hasegawa M">M Hasegawa</name></author><author><name sortKey="Ueda, M" uniqKey="Ueda M">M Ueda</name></author><author><name sortKey="Nabeshima, T" uniqKey="Nabeshima T">T Nabeshima</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Behav Brain Funct</journal-id><journal-title-group><journal-title>Behavioral and Brain Functions : BBF</journal-title></journal-title-group><issn pub-type="epub">1744-9081</issn><publisher><publisher-name>BioMed Central</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">21194415</article-id><article-id pub-id-type="pmc">3024962</article-id><article-id pub-id-type="publisher-id">1744-9081-6-77</article-id><article-id pub-id-type="doi">10.1186/1744-9081-6-77</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research</subject></subj-group></article-categories><title-group><article-title>Relationship of tooth loss to mild memory impairment and cognitive impairment: findings from the fujiwara-kyo study</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes" id="A1"><name><surname>Okamoto</surname><given-names>Nozomi</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>onozomi@naramed-u.ac.jp</email></contrib><contrib contrib-type="author" id="A2"><name><surname>Morikawa</surname><given-names>Masayuki</given-names></name><xref ref-type="aff" rid="I2">2</xref><xref ref-type="aff" rid="I3">3</xref><email>AV6M-MRKW@j.asahi-net.or.jp</email></contrib><contrib contrib-type="author" id="A3"><name><surname>Okamoto</surname><given-names>Kensuke</given-names></name><xref ref-type="aff" rid="I4">4</xref><xref ref-type="aff" rid="I5">5</xref><email>Ogt5c763387588b@ezweb.ne.jp</email></contrib><contrib contrib-type="author" id="A4"><name><surname>Habu</surname><given-names>Noboru</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>hafyan@hera.eonet.ne.jp</email></contrib><contrib contrib-type="author" id="A5"><name><surname>Iwamoto</surname><given-names>Junko</given-names></name><xref ref-type="aff" rid="I6">6</xref><email>iwamoto@y-nm.ac.jp</email></contrib><contrib contrib-type="author" id="A6"><name><surname>Tomioka</surname><given-names>Kimiko</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>tkimiko@naramed-u.ac.jp</email></contrib><contrib contrib-type="author" id="A7"><name><surname>Saeki</surname><given-names>Keigo</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>saekik@naramed-u.ac.jp</email></contrib><contrib contrib-type="author" id="A8"><name><surname>Yanagi</surname><given-names>Motokazu</given-names></name><xref ref-type="aff" rid="I7">7</xref><email>myanagi@tezukayama-u.ac.jp</email></contrib><contrib contrib-type="author" id="A9"><name><surname>Amano</surname><given-names>Nobuko</given-names></name><xref ref-type="aff" rid="I7">7</xref><email>amano@tezukayama-u.ac.jp</email></contrib><contrib contrib-type="author" id="A10"><name><surname>Kurumatani</surname><given-names>Norio</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>knorio@naramed-u.ac.jp</email></contrib></contrib-group><aff id="I1"><label>1</label>Department of Community Health and Epidemiology, Nara Medical University, Japan</aff><aff id="I2"><label>2</label>Sakai City Mental Health Center, Japan</aff><aff id="I3"><label>3</label>Department of Psychiatry, Nara Medical University, Japan</aff><aff id="I4"><label>4</label>Department of Oral and Maxillofacial Surgery, Nara Kasuga Hospital, Japan</aff><aff id="I5"><label>5</label>Department of Oral and Maxillofacial Surgery, Nara Medical University, Japan</aff><aff id="I6"><label>6</label>Department of Indoor Environmental Medicine, Nara Medical University, Japan</aff><aff id="I7"><label>7</label>Department of Food and Nutrition, Tezukayama University, Japan</aff><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>31</day><month>12</month><year>2010</year></pub-date><volume>6</volume><fpage>77</fpage><lpage>77</lpage><history><date date-type="received"><day>13</day><month>8</month><year>2010</year></date><date date-type="accepted"><day>31</day><month>12</month><year>2010</year></date></history><permissions><copyright-statement>Copyright ©2010 Okamoto et al; licensee BioMed Central Ltd.</copyright-statement><copyright-year>2010</copyright-year><copyright-holder>Okamoto et al; licensee BioMed Central Ltd.</copyright-holder><license license-type="open-access"><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><self-uri xlink:href="http://www.behavioralandbrainfunctions.com/content/6/1/77"></self-uri><abstract><sec><title>Background</title><p>This cross-sectional study investigated the relationship between the number of remaining teeth to mild memory impairment (MMI), which is a preclinical stage of dementia, and to cognitive impairment.</p></sec><sec><title>Methods</title><p>The subjects were aged 65 years or older and were grouped according to their score for the Mini-Mental State Examination (MMSE), the three-word delayed recall test in the MMSE, and the Geriatric Depression Scale into the control group (n = 3,696), the MMI group (n = 121), and the low MMSE score (23 or lower) group (n = 214). We collected data on the number of remaining teeth, the length of the edentulous period, health-related lifestyle, medical history, blood pressure, height, and body weight. Fasting venous blood samples were also obtained.</p></sec><sec><title>Results</title><p>Multiple logistic regression analysis, adjusted for depressive symptoms, age, sex, length of education, and other explanatory variables, revealed that the odds ratios of 0-10 remaining teeth to 22-32 remaining teeth were 1.679 (95% CI 1.073-2.627) for MMI and 2.177 (95% CI 1.510-3.140) for a low MMSE score. A significant relationship was also found between the length of the edentulous period and the risk of a low MMSE score (odds ratio 3.102, 95% CI 1.432-6.720) (15 years or more/less than 15 years).</p></sec><sec><title>Conclusions</title><p>Our findings suggest that tooth loss is associated with cognitive function.</p></sec></abstract></article-meta></front></pmc><affiliations><list><country><li>Japon</li></country></list><tree><country name="Japon"><noRegion><name sortKey="Okamoto, Nozomi" sort="Okamoto, Nozomi" uniqKey="Okamoto N" first="Nozomi" last="Okamoto">Nozomi Okamoto</name></noRegion><name sortKey="Amano, Nobuko" sort="Amano, Nobuko" uniqKey="Amano N" first="Nobuko" last="Amano">Nobuko Amano</name><name sortKey="Habu, Noboru" sort="Habu, Noboru" uniqKey="Habu N" first="Noboru" last="Habu">Noboru Habu</name><name sortKey="Iwamoto, Junko" sort="Iwamoto, Junko" uniqKey="Iwamoto J" first="Junko" last="Iwamoto">Junko Iwamoto</name><name sortKey="Kurumatani, Norio" sort="Kurumatani, Norio" uniqKey="Kurumatani N" first="Norio" last="Kurumatani">Norio Kurumatani</name><name sortKey="Morikawa, Masayuki" sort="Morikawa, Masayuki" uniqKey="Morikawa M" first="Masayuki" last="Morikawa">Masayuki Morikawa</name><name sortKey="Morikawa, Masayuki" sort="Morikawa, Masayuki" uniqKey="Morikawa M" first="Masayuki" last="Morikawa">Masayuki Morikawa</name><name sortKey="Okamoto, Kensuke" sort="Okamoto, Kensuke" uniqKey="Okamoto K" first="Kensuke" last="Okamoto">Kensuke Okamoto</name><name sortKey="Okamoto, Kensuke" sort="Okamoto, Kensuke" uniqKey="Okamoto K" first="Kensuke" last="Okamoto">Kensuke Okamoto</name><name sortKey="Saeki, Keigo" sort="Saeki, Keigo" uniqKey="Saeki K" first="Keigo" last="Saeki">Keigo Saeki</name><name sortKey="Tomioka, Kimiko" sort="Tomioka, Kimiko" uniqKey="Tomioka K" first="Kimiko" last="Tomioka">Kimiko Tomioka</name><name sortKey="Yanagi, Motokazu" sort="Yanagi, Motokazu" uniqKey="Yanagi M" first="Motokazu" last="Yanagi">Motokazu Yanagi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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