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Bilateral maxillary sinus floor augmentation with tissue-engineered autologous osteoblasts and demineralized freeze-dried bone

Identifieur interne : 000F88 ( Pmc/Checkpoint ); précédent : 000F87; suivant : 000F89

Bilateral maxillary sinus floor augmentation with tissue-engineered autologous osteoblasts and demineralized freeze-dried bone

Auteurs : Aashish Deshmukh ; Rinku Kalra ; Shruti Chhadva ; Angad Shetye

Source :

RBID : PMC:4456751

Abstract

The pneumatization of the maxillary sinus often results in a lack of sufficient alveolar bone for implant placement. In the last decades, maxillary sinus lift has become a very popular procedure with predictable results. Sinus floor augmentation procedures are generally carried out using autologous bone grafts, bone substitutes, or composites of bone and bone substitutes. However, the inherent limitations associated with each of these, have directed the attention of investigators to new technologies like bone tissue engineering. Bone marrow stromal cells have been regarded as multi-potent cells residing in bone marrow. These cells can be harvested from a person, multiplied outside his body using bioengineering principles and technologies and later introduced into a tissue defect. We present a case where tissue-engineered autologous osteoblasts were used along with demineralized freeze-dried bone for sinus floor augmentation.


Url:
DOI: 10.4103/0976-237X.156057
PubMed: 26097364
PubMed Central: 4456751


Affiliations:


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<p>The pneumatization of the maxillary sinus often results in a lack of sufficient alveolar bone for implant placement. In the last decades, maxillary sinus lift has become a very popular procedure with predictable results. Sinus floor augmentation procedures are generally carried out using autologous bone grafts, bone substitutes, or composites of bone and bone substitutes. However, the inherent limitations associated with each of these, have directed the attention of investigators to new technologies like bone tissue engineering. Bone marrow stromal cells have been regarded as multi-potent cells residing in bone marrow. These cells can be harvested from a person, multiplied outside his body using bioengineering principles and technologies and later introduced into a tissue defect. We present a case where tissue-engineered autologous osteoblasts were used along with demineralized freeze-dried bone for sinus floor augmentation.</p>
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<journal-id journal-id-type="nlm-ta">Contemp Clin Dent</journal-id>
<journal-id journal-id-type="iso-abbrev">Contemp Clin Dent</journal-id>
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<name>
<surname>Deshmukh</surname>
<given-names>Aashish</given-names>
</name>
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<surname>Kalra</surname>
<given-names>Rinku</given-names>
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<surname>Chhadva</surname>
<given-names>Shruti</given-names>
</name>
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<name>
<surname>Shetye</surname>
<given-names>Angad</given-names>
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<aff id="aff1">
<italic>Department of Oral and Maxillofacial Surgery, YMT Dental College and Hospital, Mumbai, Maharashtra, India</italic>
</aff>
<author-notes>
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<bold>Correspondence:</bold>
Dr. Aashish Deshmukh, Department of Oral and Maxillofacial Surgery, YMT Dental College and Hospital, Institutional Area, Sector 4, Kharghar, Navi Mumbai - 410 210, Maharashtra, India. E-mail:
<email xlink:href="deshmukhaashish@gmail.com">deshmukhaashish@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<season>Apr-Jun</season>
<year>2015</year>
</pub-date>
<volume>6</volume>
<issue>2</issue>
<fpage>243</fpage>
<lpage>246</lpage>
<permissions>
<copyright-statement>Copyright: © Contemporary Clinical Dentistry</copyright-statement>
<copyright-year>2015</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0">
<license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract>
<p>The pneumatization of the maxillary sinus often results in a lack of sufficient alveolar bone for implant placement. In the last decades, maxillary sinus lift has become a very popular procedure with predictable results. Sinus floor augmentation procedures are generally carried out using autologous bone grafts, bone substitutes, or composites of bone and bone substitutes. However, the inherent limitations associated with each of these, have directed the attention of investigators to new technologies like bone tissue engineering. Bone marrow stromal cells have been regarded as multi-potent cells residing in bone marrow. These cells can be harvested from a person, multiplied outside his body using bioengineering principles and technologies and later introduced into a tissue defect. We present a case where tissue-engineered autologous osteoblasts were used along with demineralized freeze-dried bone for sinus floor augmentation.</p>
</abstract>
<kwd-group>
<kwd>Autologous osteoblast implantation</kwd>
<kwd>bone grafting</kwd>
<kwd>sinus floor augmentation</kwd>
<kwd>tissue engineering</kwd>
</kwd-group>
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