Leukemic gingival enlargement: Report of a rare case with review of literature
Identifieur interne : 000D05 ( Pmc/Checkpoint ); précédent : 000D04; suivant : 000D06Leukemic gingival enlargement: Report of a rare case with review of literature
Auteurs : Shamimul Hasan [Inde] ; Nabeel Ishrat Khan [Inde] ; L Bhaskar Reddy [Inde]Source :
- International Journal of Applied and Basic Medical Research [ 2229-516X ] ; 2015.
Abstract
Oral cavity functions as an early indicator for a variety of systemic diseases. Early and accurate diagnosis of these underlying systemic disorders entails thorough examination of the oral mucosa, gingiva, teeth, tongue and other oral tissues. Although gingival changes may be related to local factors in the oral cavity, it can also be an expression of systemic conditions such as blood dyscrasias, endocrinal imbalance, and nutritional deficiencies. Leukemia, a malignancy of white blood cells is a dreadful disease, which, if not diagnosed properly and treated early may result in significant morbidity and mortality. Oral changes may be the first and only presenting signs in leukemic patients. This paper aims to throw light on an interesting case of acute leukemia diagnosed on the basis of oral signs and emphasizes the importance of thorough oral examination to identify the threatening condition.
Url:
DOI: 10.4103/2229-516X.149251
PubMed: 25664273
PubMed Central: 4318106
Affiliations:
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<front><div type="abstract" xml:lang="en"><p>Oral cavity functions as an early indicator for a variety of systemic diseases. Early and accurate diagnosis of these underlying systemic disorders entails thorough examination of the oral mucosa, gingiva, teeth, tongue and other oral tissues. Although gingival changes may be related to local factors in the oral cavity, it can also be an expression of systemic conditions such as blood dyscrasias, endocrinal imbalance, and nutritional deficiencies. Leukemia, a malignancy of white blood cells is a dreadful disease, which, if not diagnosed properly and treated early may result in significant morbidity and mortality. Oral changes may be the first and only presenting signs in leukemic patients. This paper aims to throw light on an interesting case of acute leukemia diagnosed on the basis of oral signs and emphasizes the importance of thorough oral examination to identify the threatening condition.</p>
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Int J Appl Basic Med Res</journal-id>
<journal-id journal-id-type="iso-abbrev">Int J Appl Basic Med Res</journal-id>
<journal-id journal-id-type="publisher-id">IJABMR</journal-id>
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<article-id pub-id-type="pmc">4318106</article-id>
<article-id pub-id-type="publisher-id">IJABMR-5-65</article-id>
<article-id pub-id-type="doi">10.4103/2229-516X.149251</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject>
</subj-group>
</article-categories>
<title-group><article-title>Leukemic gingival enlargement: Report of a rare case with review of literature</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Hasan</surname>
<given-names>Shamimul</given-names>
</name>
<xref ref-type="aff" rid="aff1"></xref>
<xref ref-type="corresp" rid="cor1"></xref>
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<contrib contrib-type="author"><name><surname>Khan</surname>
<given-names>Nabeel Ishrat</given-names>
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<xref ref-type="aff" rid="aff2">1</xref>
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<contrib contrib-type="author"><name><surname>Reddy</surname>
<given-names>L Bhaskar</given-names>
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<xref ref-type="aff" rid="aff3">2</xref>
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<aff id="aff1">Department of Oral Medicine and Radiology, Faculty of Dentistry, Jamia Millia Islamia, Okhla, New Delhi, India</aff>
<aff id="aff2"><label>1</label>
Department of Oral Medicine and Radiology, ZA Dental College and Hospitals, A.M.U., Aligarh, Uttar Pradesh, India</aff>
<aff id="aff3"><label>2</label>
Department of Oral Medicine and Radiology, Kalinga Institute of Dental Sciences, KIIT University, Patia, Bubaneswar, Odisha, India</aff>
<author-notes><corresp id="cor1"><bold>Address for correspondence:</bold>
Dr. Shamimul Hasan, C/o Mohd. Javed Khan, C-4, Duplex Quarters (New), Sir Syed Nager, Aligarh, Uttar Pradesh, India. E-mail: <email xlink:href="shamim0571@gmail.com">shamim0571@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><season>Jan-Apr</season>
<year>2015</year>
</pub-date>
<volume>5</volume>
<issue>1</issue>
<fpage>65</fpage>
<lpage>67</lpage>
<history><date date-type="received"><day>22</day>
<month>5</month>
<year>2014</year>
</date>
<date date-type="accepted"><day>11</day>
<month>7</month>
<year>2014</year>
</date>
</history>
<permissions><copyright-statement>Copyright: © International Journal of Applied and Basic Medical Research</copyright-statement>
<copyright-year>2015</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract><p>Oral cavity functions as an early indicator for a variety of systemic diseases. Early and accurate diagnosis of these underlying systemic disorders entails thorough examination of the oral mucosa, gingiva, teeth, tongue and other oral tissues. Although gingival changes may be related to local factors in the oral cavity, it can also be an expression of systemic conditions such as blood dyscrasias, endocrinal imbalance, and nutritional deficiencies. Leukemia, a malignancy of white blood cells is a dreadful disease, which, if not diagnosed properly and treated early may result in significant morbidity and mortality. Oral changes may be the first and only presenting signs in leukemic patients. This paper aims to throw light on an interesting case of acute leukemia diagnosed on the basis of oral signs and emphasizes the importance of thorough oral examination to identify the threatening condition.</p>
</abstract>
<kwd-group><kwd>Gingival enlargement</kwd>
<kwd>leukemia</kwd>
<kwd>oral manifestations</kwd>
</kwd-group>
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