Association of chronic periodontitis with metabolic syndrome: A cross-sectional study
Identifieur interne : 000866 ( Pmc/Checkpoint ); précédent : 000865; suivant : 000867Association of chronic periodontitis with metabolic syndrome: A cross-sectional study
Auteurs : Naresh Kumar ; Ashu Bhardwaj ; Prakash Chand Negi ; Pravesh Kumar Jhingta ; Deepak Sharma ; Vinay Kumar BhardwajSource :
- Journal of Indian Society of Periodontology [ 0972-124X ] ; 2016.
Abstract
Prevalence of metabolic syndrome (MeS) is high among Asians, including Indians and is rising, particularly with the adoption of modernized lifestyle. Various studies have reported a significant relationship between periodontal status and MeS. The objective of this study is to investigate the association between periodontitis and MeS.
The study included 259 subjects (130 cases with chronic periodontitis, 129 controls without chronic periodontitis) who underwent medical and periodontal checkup. Five components (obesity, high blood pressure, low- and high-density lipoproteins, cholesterol, hypertriglyceridemia, and high plasma glucose) of MeS were evaluated, and individuals with ≥3 positive components were defined as having MeS. The periodontal parameter was clinical attachment level (CAL) on the basis of which cases were selected with moderate (CAL loss 3–4 mm) and severe (CAL loss ≥5 mm) generalized chronic periodontitis. The association between chronic periodontitis and MeS components was investigated using odds ratios (ORs) and 95% confidence intervals (CIs).
The association of MeS and chronic periodontitis was strong and significant with OR: 2.64, 95% CI: 1.36–5.18, and
The results of this study suggest that there is a strong association between chronic periodontitis and MeS. The association was independent of the various potential confounding risk factors affecting the chronic periodontitis such as age, sex, residential background, and tobacco consumption.
Url:
DOI: 10.4103/0972-124X.183096
PubMed: 27563208
PubMed Central: 4976555
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Association of chronic periodontitis with metabolic syndrome: A cross-sectional study</title><author><name sortKey="Kumar, Naresh" sort="Kumar, Naresh" uniqKey="Kumar N" first="Naresh" last="Kumar">Naresh Kumar</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Bhardwaj, Ashu" sort="Bhardwaj, Ashu" uniqKey="Bhardwaj A" first="Ashu" last="Bhardwaj">Ashu Bhardwaj</name><affiliation><nlm:aff id="aff2"><italic>Department of Periodontology, Dental Faculty, Jamia Millia Islamia, New Delhi, India</italic></nlm:aff></affiliation></author><author><name sortKey="Negi, Prakash Chand" sort="Negi, Prakash Chand" uniqKey="Negi P" first="Prakash Chand" last="Negi">Prakash Chand Negi</name><affiliation><nlm:aff id="aff3"><italic>Department of Cardiology, Indira Gandhi Medical College and Hospital, Shimla, Himachal Pradesh, India</italic></nlm:aff></affiliation></author><author><name sortKey="Jhingta, Pravesh Kumar" sort="Jhingta, Pravesh Kumar" uniqKey="Jhingta P" first="Pravesh Kumar" last="Jhingta">Pravesh Kumar Jhingta</name><affiliation><nlm:aff id="aff4"><italic>Department of Periodontology, H.P. Government Dental College and Hospital, Shimla, Himachal Pradesh, India</italic></nlm:aff></affiliation></author><author><name sortKey="Sharma, Deepak" sort="Sharma, Deepak" uniqKey="Sharma D" first="Deepak" last="Sharma">Deepak Sharma</name><affiliation><nlm:aff id="aff4"><italic>Department of Periodontology, H.P. Government Dental College and Hospital, Shimla, Himachal Pradesh, India</italic></nlm:aff></affiliation></author><author><name sortKey="Bhardwaj, Vinay Kumar" sort="Bhardwaj, Vinay Kumar" uniqKey="Bhardwaj V" first="Vinay Kumar" last="Bhardwaj">Vinay Kumar Bhardwaj</name><affiliation><nlm:aff id="aff5"><italic>Department of Public Health Dentistry, H.P. Government Dental College and Hospital, Shimla, Himachal Pradesh, India</italic></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27563208</idno><idno type="pmc">4976555</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976555</idno><idno type="RBID">PMC:4976555</idno><idno type="doi">10.4103/0972-124X.183096</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">003182</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003182</idno><idno type="wicri:Area/Pmc/Curation">003182</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003182</idno><idno type="wicri:Area/Pmc/Checkpoint">000866</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000866</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Association of chronic periodontitis with metabolic syndrome: A cross-sectional study</title><author><name sortKey="Kumar, Naresh" sort="Kumar, Naresh" uniqKey="Kumar N" first="Naresh" last="Kumar">Naresh Kumar</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Bhardwaj, Ashu" sort="Bhardwaj, Ashu" uniqKey="Bhardwaj A" first="Ashu" last="Bhardwaj">Ashu Bhardwaj</name><affiliation><nlm:aff id="aff2"><italic>Department of Periodontology, Dental Faculty, Jamia Millia Islamia, New Delhi, India</italic></nlm:aff></affiliation></author><author><name sortKey="Negi, Prakash Chand" sort="Negi, Prakash Chand" uniqKey="Negi P" first="Prakash Chand" last="Negi">Prakash Chand Negi</name><affiliation><nlm:aff id="aff3"><italic>Department of Cardiology, Indira Gandhi Medical College and Hospital, Shimla, Himachal Pradesh, India</italic></nlm:aff></affiliation></author><author><name sortKey="Jhingta, Pravesh Kumar" sort="Jhingta, Pravesh Kumar" uniqKey="Jhingta P" first="Pravesh Kumar" last="Jhingta">Pravesh Kumar Jhingta</name><affiliation><nlm:aff id="aff4"><italic>Department of Periodontology, H.P. Government Dental College and Hospital, Shimla, Himachal Pradesh, India</italic></nlm:aff></affiliation></author><author><name sortKey="Sharma, Deepak" sort="Sharma, Deepak" uniqKey="Sharma D" first="Deepak" last="Sharma">Deepak Sharma</name><affiliation><nlm:aff id="aff4"><italic>Department of Periodontology, H.P. Government Dental College and Hospital, Shimla, Himachal Pradesh, India</italic></nlm:aff></affiliation></author><author><name sortKey="Bhardwaj, Vinay Kumar" sort="Bhardwaj, Vinay Kumar" uniqKey="Bhardwaj V" first="Vinay Kumar" last="Bhardwaj">Vinay Kumar Bhardwaj</name><affiliation><nlm:aff id="aff5"><italic>Department of Public Health Dentistry, H.P. Government Dental College and Hospital, Shimla, Himachal Pradesh, India</italic></nlm:aff></affiliation></author></analytic><series><title level="j">Journal of Indian Society of Periodontology</title><idno type="ISSN">0972-124X</idno><idno type="eISSN">0975-1580</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="st1"><title>Background:</title><p>Prevalence of metabolic syndrome (MeS) is high among Asians, including Indians and is rising, particularly with the adoption of modernized lifestyle. Various studies have reported a significant relationship between periodontal status and MeS. The objective of this study is to investigate the association between periodontitis and MeS.</p></sec><sec id="st2"><title>Materials and Methods:</title><p>The study included 259 subjects (130 cases with chronic periodontitis, 129 controls without chronic periodontitis) who underwent medical and periodontal checkup. Five components (obesity, high blood pressure, low- and high-density lipoproteins, cholesterol, hypertriglyceridemia, and high plasma glucose) of MeS were evaluated, and individuals with ≥3 positive components were defined as having MeS. The periodontal parameter was clinical attachment level (CAL) on the basis of which cases were selected with moderate (CAL loss 3–4 mm) and severe (CAL loss ≥5 mm) generalized chronic periodontitis. The association between chronic periodontitis and MeS components was investigated using odds ratios (ORs) and 95% confidence intervals (CIs).</p></sec><sec id="st3"><title>Results:</title><p>The association of MeS and chronic periodontitis was strong and significant with OR: 2.64, 95% CI: 1.36–5.18, and <italic>P</italic> < 0.003. Comparison of mean values of components of MeS between cases and controls reveals that the mean waist circumference (mean difference: −4.8 [95% CI: 7.75–−1.84], <italic>P</italic> < 0.002) and mean triglycerides level (mean difference: −25.75 [95% CI: −49.22–−2.28], <italic>P</italic> < 0.032) were significantly higher in cases than in control groups. Although mean systolic blood pressure, diastolic blood pressure, and fasting blood sugar level were higher in cases (125.77, 82.99 and 86.38, respectively) compared with control (122.81, 81.3 and 83.68, respectively), it was statistically insignificant.</p></sec><sec id="st4"><title>Conclusion:</title><p>The results of this study suggest that there is a strong association between chronic periodontitis and MeS. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">J Indian Soc Periodontol</journal-id><journal-id journal-id-type="iso-abbrev">J Indian Soc Periodontol</journal-id><journal-id journal-id-type="publisher-id">JISP</journal-id><journal-title-group><journal-title>Journal of Indian Society of Periodontology</journal-title></journal-title-group><issn pub-type="ppub">0972-124X</issn><issn pub-type="epub">0975-1580</issn><publisher><publisher-name>Medknow Publications & Media Pvt Ltd</publisher-name><publisher-loc>India</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27563208</article-id><article-id pub-id-type="pmc">4976555</article-id><article-id pub-id-type="publisher-id">JISP-20-324</article-id><article-id pub-id-type="doi">10.4103/0972-124X.183096</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>Association of chronic periodontitis with metabolic syndrome: A cross-sectional study</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Kumar</surname><given-names>Naresh</given-names></name><xref ref-type="aff" rid="aff1"></xref><xref ref-type="corresp" rid="cor1"></xref></contrib><contrib contrib-type="author"><name><surname>Bhardwaj</surname><given-names>Ashu</given-names></name><xref ref-type="aff" rid="aff2">1</xref></contrib><contrib contrib-type="author"><name><surname>Negi</surname><given-names>Prakash Chand</given-names></name><xref ref-type="aff" rid="aff3">2</xref></contrib><contrib contrib-type="author"><name><surname>Jhingta</surname><given-names>Pravesh Kumar</given-names></name><xref ref-type="aff" rid="aff4">3</xref></contrib><contrib contrib-type="author"><name><surname>Sharma</surname><given-names>Deepak</given-names></name><xref ref-type="aff" rid="aff4">3</xref></contrib><contrib contrib-type="author"><name><surname>Bhardwaj</surname><given-names>Vinay Kumar</given-names></name><xref ref-type="aff" rid="aff5">4</xref></contrib></contrib-group><aff id="aff1"><italic>Department of Periodontology, Maharaj Ganga Singh Dental College and Research Centre, Sri Ganganagar, Rajasthan, India</italic></aff><aff id="aff2"><label>1</label><italic>Department of Periodontology, Dental Faculty, Jamia Millia Islamia, New Delhi, India</italic></aff><aff id="aff3"><label>2</label><italic>Department of Cardiology, Indira Gandhi Medical College and Hospital, Shimla, Himachal Pradesh, India</italic></aff><aff id="aff4"><label>3</label><italic>Department of Periodontology, H.P. Government Dental College and Hospital, Shimla, Himachal Pradesh, India</italic></aff><aff id="aff5"><label>4</label><italic>Department of Public Health Dentistry, H.P. Government Dental College and Hospital, Shimla, Himachal Pradesh, India</italic></aff><author-notes><corresp id="cor1"><bold>Address for correspondence:</bold> Dr. Naresh Kumar, Department of Periodontology, Maharaj Ganga Singh Dental College and Research Centre, Sri Ganganagar, Rajasthan, India. E-mail: <email xlink:href="jnishu.naresh@gmail.com">jnishu.naresh@gmail.com</email></corresp></author-notes><pub-date pub-type="ppub"><season>May-Jun</season><year>2016</year></pub-date><volume>20</volume><issue>3</issue><fpage>324</fpage><lpage>329</lpage><history><date date-type="received"><day>06</day><month>1</month><year>2015</year></date><date date-type="accepted"><day>19</day><month>4</month><year>2016</year></date></history><permissions><copyright-statement>Copyright: © Journal of Indian Society of Periodontology</copyright-statement><copyright-year>2016</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0"><license-p>This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.</license-p></license></permissions><abstract><sec id="st1"><title>Background:</title><p>Prevalence of metabolic syndrome (MeS) is high among Asians, including Indians and is rising, particularly with the adoption of modernized lifestyle. Various studies have reported a significant relationship between periodontal status and MeS. The objective of this study is to investigate the association between periodontitis and MeS.</p></sec><sec id="st2"><title>Materials and Methods:</title><p>The study included 259 subjects (130 cases with chronic periodontitis, 129 controls without chronic periodontitis) who underwent medical and periodontal checkup. Five components (obesity, high blood pressure, low- and high-density lipoproteins, cholesterol, hypertriglyceridemia, and high plasma glucose) of MeS were evaluated, and individuals with ≥3 positive components were defined as having MeS. The periodontal parameter was clinical attachment level (CAL) on the basis of which cases were selected with moderate (CAL loss 3–4 mm) and severe (CAL loss ≥5 mm) generalized chronic periodontitis. The association between chronic periodontitis and MeS components was investigated using odds ratios (ORs) and 95% confidence intervals (CIs).</p></sec><sec id="st3"><title>Results:</title><p>The association of MeS and chronic periodontitis was strong and significant with OR: 2.64, 95% CI: 1.36–5.18, and <italic>P</italic> < 0.003. Comparison of mean values of components of MeS between cases and controls reveals that the mean waist circumference (mean difference: −4.8 [95% CI: 7.75–−1.84], <italic>P</italic> < 0.002) and mean triglycerides level (mean difference: −25.75 [95% CI: −49.22–−2.28], <italic>P</italic> < 0.032) were significantly higher in cases than in control groups. Although mean systolic blood pressure, diastolic blood pressure, and fasting blood sugar level were higher in cases (125.77, 82.99 and 86.38, respectively) compared with control (122.81, 81.3 and 83.68, respectively), it was statistically insignificant.</p></sec><sec id="st4"><title>Conclusion:</title><p>The results of this study suggest that there is a strong association between chronic periodontitis and MeS. The association was independent of the various potential confounding risk factors affecting the chronic periodontitis such as age, sex, residential background, and tobacco consumption.</p></sec></abstract><kwd-group><title>Key words</title><kwd>Chronic periodontitis</kwd><kwd>hypertriglyceridemia</kwd><kwd>metabolic syndrome</kwd><kwd>obesity</kwd><kwd>plasma glucose</kwd></kwd-group></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Bhardwaj, Ashu" sort="Bhardwaj, Ashu" uniqKey="Bhardwaj A" first="Ashu" last="Bhardwaj">Ashu Bhardwaj</name><name sortKey="Bhardwaj, Vinay Kumar" sort="Bhardwaj, Vinay Kumar" uniqKey="Bhardwaj V" first="Vinay Kumar" last="Bhardwaj">Vinay Kumar Bhardwaj</name><name sortKey="Jhingta, Pravesh Kumar" sort="Jhingta, Pravesh Kumar" uniqKey="Jhingta P" first="Pravesh Kumar" last="Jhingta">Pravesh Kumar Jhingta</name><name sortKey="Kumar, Naresh" sort="Kumar, Naresh" uniqKey="Kumar N" first="Naresh" last="Kumar">Naresh Kumar</name><name sortKey="Negi, Prakash Chand" sort="Negi, Prakash Chand" uniqKey="Negi P" first="Prakash Chand" last="Negi">Prakash Chand Negi</name><name sortKey="Sharma, Deepak" sort="Sharma, Deepak" uniqKey="Sharma D" first="Deepak" last="Sharma">Deepak Sharma</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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