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Osseointegration aspects of placed implant in bone reconstruction with newly developed block-type interconnected porous calcium hydroxyapatite

Identifieur interne : 000553 ( Pmc/Checkpoint ); précédent : 000552; suivant : 000554

Osseointegration aspects of placed implant in bone reconstruction with newly developed block-type interconnected porous calcium hydroxyapatite

Auteurs : Kazuya Doi ; Takayasu Kubo ; Yusuke Makihara ; Hiroshi Oue ; Koji Morita ; Yoshifumi Oki ; Shiho Kajihara ; Kazuhiro Tsuga

Source :

RBID : PMC:4990360

Abstract

ABSTRACT

Artificial bone has been employed to reconstruct bone defects. However, only few reports on implant placement after block bone grafting exist.

Objectives

The purpose of this study was to evaluate the osseointegration of dental implant in bone reconstructions with interconnected porous calcium hydroxyapatite (IP-CHA).

Material and Methods

The IP-CHA cylinders (D; 4.3 mm, H; 10.0 mm) were placed into bone sockets in each side of the femurs of four male dogs. The IP-CHA on the right side was a 24-week sample. Twelve weeks after placement, a titanium implant was placed into a socket that was prepared in half of the placed IP-CHA cylinder on the right side. On the left side, another IP-CHA cylinder was placed as a 12-week sample. After another 12 weeks, the samples were harvested, and the bone regeneration and bone-implant contact (BIC) ratios were measured.

Results

New bone formation area was superior in the 24-week IP-CHA compared with the 12-week IP-CHA. BIC was not significantly different between IP-CHA and the parent sites. Osseointegration was detected around the implant in IP-CHA-reconstructed bone.

Conclusion

Our preliminary results suggest that IP-CHA may be a suitable bone graft material for reconstructing bones that require implant placement.


Url:
DOI: 10.1590/1678-775720150597
PubMed: 27556202
PubMed Central: 4990360


Affiliations:


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PMC:4990360

Le document en format XML

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<title>ABSTRACT</title>
<p>Artificial bone has been employed to reconstruct bone defects. However, only few reports on implant placement after block bone grafting exist. </p>
<sec>
<title>Objectives</title>
<p> The purpose of this study was to evaluate the osseointegration of dental implant in bone reconstructions with interconnected porous calcium hydroxyapatite (IP-CHA).</p>
</sec>
<sec>
<title>Material and Methods</title>
<p> The IP-CHA cylinders (D; 4.3 mm, H; 10.0 mm) were placed into bone sockets in each side of the femurs of four male dogs. The IP-CHA on the right side was a 24-week sample. Twelve weeks after placement, a titanium implant was placed into a socket that was prepared in half of the placed IP-CHA cylinder on the right side. On the left side, another IP-CHA cylinder was placed as a 12-week sample. After another 12 weeks, the samples were harvested, and the bone regeneration and bone-implant contact (BIC) ratios were measured.</p>
</sec>
<sec>
<title>Results</title>
<p> New bone formation area was superior in the 24-week IP-CHA compared with the 12-week IP-CHA. BIC was not significantly different between IP-CHA and the parent sites. Osseointegration was detected around the implant in IP-CHA-reconstructed bone.</p>
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<title>Conclusion</title>
<p> Our preliminary results suggest that IP-CHA may be a suitable bone graft material for reconstructing bones that require implant placement.</p>
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<name sortKey="Kubo, T" uniqKey="Kubo T">T Kubo</name>
</author>
<author>
<name sortKey="Doi, K" uniqKey="Doi K">K Doi</name>
</author>
<author>
<name sortKey="Morita, K" uniqKey="Morita K">K Morita</name>
</author>
<author>
<name sortKey="Takeshita, R" uniqKey="Takeshita R">R Takeshita</name>
</author>
<author>
<name sortKey="Katoh, S" uniqKey="Katoh S">S Katoh</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="research-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">J Appl Oral Sci</journal-id>
<journal-id journal-id-type="iso-abbrev">J Appl Oral Sci</journal-id>
<journal-id journal-id-type="publisher-id">jaos</journal-id>
<journal-title-group>
<journal-title>Journal of Applied Oral Science</journal-title>
</journal-title-group>
<issn pub-type="ppub">1678-7757</issn>
<issn pub-type="epub">1678-7765</issn>
<publisher>
<publisher-name>Faculdade De Odontologia De Bauru - USP</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">27556202</article-id>
<article-id pub-id-type="pmc">4990360</article-id>
<article-id pub-id-type="publisher-id">1678-775720150597</article-id>
<article-id pub-id-type="doi">10.1590/1678-775720150597</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Original Articles</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Osseointegration aspects of placed implant in bone reconstruction with newly developed block-type interconnected porous calcium hydroxyapatite</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>DOI</surname>
<given-names>Kazuya</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>KUBO</surname>
<given-names>Takayasu</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>MAKIHARA</surname>
<given-names>Yusuke</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>OUE</surname>
<given-names>Hiroshi</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>MORITA</surname>
<given-names>Koji</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>OKI</surname>
<given-names>Yoshifumi</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>KAJIHARA</surname>
<given-names>Shiho</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>TSUGA</surname>
<given-names>Kazuhiro</given-names>
</name>
</contrib>
</contrib-group>
<aff id="aff1">Hiroshima University Graduate School of Biomedical and Health Sciences</aff>
<author-notes>
<corresp id="c01">
<bold>Corresponding address:</bold>
Kazuya Doi - Department of Advanced Prosthodontics, Hiroshima University Graduate School of Biomedical Sciences 1-2-3 - Kasumi - Minami-ku - Hiroshima - 734-8553 - Japan - Phone: +81 82 257 5677 - Fax: +81 82 257 5679 - e-mail:
<email>kazuya17@hiroshima-u.ac.jp</email>
</corresp>
<fn fn-type="conflict">
<p>CONFLICTS OF INTEREST</p>
<p>The authors have no financial interest in any company or in any of the products mentioned in this article.</p>
</fn>
</author-notes>
<pub-date pub-type="epub-ppub">
<season>Jul-Aug</season>
<year>2016</year>
</pub-date>
<pmc-comment>Fake ppub date generated by PMC from publisher pub-date/@pub-type='epub-ppub' </pmc-comment>
<pub-date pub-type="ppub">
<season>Jul-Aug</season>
<year>2016</year>
</pub-date>
<volume>24</volume>
<issue>4</issue>
<fpage>325</fpage>
<lpage>331</lpage>
<history>
<date date-type="received">
<day>6</day>
<month>1</month>
<year>2016</year>
</date>
<date date-type="rev-recd">
<day>23</day>
<month>2</month>
<year>2016</year>
</date>
<date date-type="accepted">
<day>20</day>
<month>3</month>
<year>2016</year>
</date>
</history>
<permissions>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p> This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. </license-p>
</license>
</permissions>
<abstract>
<title>ABSTRACT</title>
<p>Artificial bone has been employed to reconstruct bone defects. However, only few reports on implant placement after block bone grafting exist. </p>
<sec>
<title>Objectives</title>
<p> The purpose of this study was to evaluate the osseointegration of dental implant in bone reconstructions with interconnected porous calcium hydroxyapatite (IP-CHA).</p>
</sec>
<sec>
<title>Material and Methods</title>
<p> The IP-CHA cylinders (D; 4.3 mm, H; 10.0 mm) were placed into bone sockets in each side of the femurs of four male dogs. The IP-CHA on the right side was a 24-week sample. Twelve weeks after placement, a titanium implant was placed into a socket that was prepared in half of the placed IP-CHA cylinder on the right side. On the left side, another IP-CHA cylinder was placed as a 12-week sample. After another 12 weeks, the samples were harvested, and the bone regeneration and bone-implant contact (BIC) ratios were measured.</p>
</sec>
<sec>
<title>Results</title>
<p> New bone formation area was superior in the 24-week IP-CHA compared with the 12-week IP-CHA. BIC was not significantly different between IP-CHA and the parent sites. Osseointegration was detected around the implant in IP-CHA-reconstructed bone.</p>
</sec>
<sec>
<title>Conclusion</title>
<p> Our preliminary results suggest that IP-CHA may be a suitable bone graft material for reconstructing bones that require implant placement.</p>
</sec>
</abstract>
<kwd-group>
<kwd>Implant</kwd>
<kwd>Hydroxyapatite</kwd>
<kwd>Bone regeneration</kwd>
</kwd-group>
<counts>
<fig-count count="7"></fig-count>
<table-count count="1"></table-count>
<equation-count count="0"></equation-count>
<ref-count count="30"></ref-count>
<page-count count="7"></page-count>
</counts>
</article-meta>
</front>
</pmc>
<affiliations>
<list></list>
<tree>
<noCountry>
<name sortKey="Doi, Kazuya" sort="Doi, Kazuya" uniqKey="Doi K" first="Kazuya" last="Doi">Kazuya Doi</name>
<name sortKey="Kajihara, Shiho" sort="Kajihara, Shiho" uniqKey="Kajihara S" first="Shiho" last="Kajihara">Shiho Kajihara</name>
<name sortKey="Kubo, Takayasu" sort="Kubo, Takayasu" uniqKey="Kubo T" first="Takayasu" last="Kubo">Takayasu Kubo</name>
<name sortKey="Makihara, Yusuke" sort="Makihara, Yusuke" uniqKey="Makihara Y" first="Yusuke" last="Makihara">Yusuke Makihara</name>
<name sortKey="Morita, Koji" sort="Morita, Koji" uniqKey="Morita K" first="Koji" last="Morita">Koji Morita</name>
<name sortKey="Oki, Yoshifumi" sort="Oki, Yoshifumi" uniqKey="Oki Y" first="Yoshifumi" last="Oki">Yoshifumi Oki</name>
<name sortKey="Oue, Hiroshi" sort="Oue, Hiroshi" uniqKey="Oue H" first="Hiroshi" last="Oue">Hiroshi Oue</name>
<name sortKey="Tsuga, Kazuhiro" sort="Tsuga, Kazuhiro" uniqKey="Tsuga K" first="Kazuhiro" last="Tsuga">Kazuhiro Tsuga</name>
</noCountry>
</tree>
</affiliations>
</record>

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