Role of lipids in the transmission of the infective stage (L3) of Strongylus vulgaris (Nematoda: Strongylida)
Identifieur interne : 000789 ( PascalFrancis/Corpus ); précédent : 000788; suivant : 000790Role of lipids in the transmission of the infective stage (L3) of Strongylus vulgaris (Nematoda: Strongylida)
Auteurs : D. L. Medica ; M. V. K. SukhdeoSource :
- The Journal of parasitology [ 0022-3395 ] ; 1997.
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Abstract
Infective larvae (L3) of Strongylus vulgaris have limited energy stores for host finding and for infection. For transmission to occur, the larvae must have sufficient energy to (a) migrate onto grass, where they are ingested by their equine host (host finding), and (b) penetrate into the host gut. This study is designed to test the hypothesis that L3 larvae of S. vulgaris partition their energy stores between locomotory activity (used in host finding) and infection activity (penetration). Chronic locomotory activity was stimulated by incubating S. vulgaris L3 larvae at a constant temperature (38 C). After 8 days of treatment, locomotory activity ceased (exhaustion). Exhausted L3 larvae had significantly decreased total lipid when compared to controls (P < 0.05), but there was no decrease in levels of protein or carbohydrate. Lipids of S. vulgaris L3 larvae are comprised of 9 fatty acids, some of which are depleted in exhausted worms (14:0, 14:1, 16:0, 16:1, 18:1, 18:2), whereas others (18:0, 20:4, 24: 0) remain unchanged. These data suggest that specific fatty acids provide the energy source for locomotory activity in S. vulgaris. Exhausted L3 larvae were also less able to penetrate host cecal tissue in in vitro penetration assays when compared to controls (P < 0.05), suggesting that the depletion of individual fatty acids during locomotory activity also reduced infectivity. These data do not support the hypothesis that S. vulgaris L3 larvae partition their energy stores between host-finding and infection activities. A comparison of lipid storage profiles in the L3 larvae of 4 nematode species with similar transmission strategies (S. vulgaris, Strongylus edentatus, Strongylus equinus, and Haemonchus contortus) revealed similarities in the fatty acid composition of these species. These data suggest a relationship between transmission patterns and energy storage strategies in the L3 larvae of nematode parasites of vertebrates.
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| NO : | PASCAL 98-0017325 INIST |
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| ET : | Role of lipids in the transmission of the infective stage (L3) of Strongylus vulgaris (Nematoda: Strongylida) |
| AU : | MEDICA (D. L.); SUKHDEO (M. V. K.) |
| AF : | Department of Animal Sciences, Rutgers University/New Brunswick, New Jersey 08903/Etats-Unis (1 aut., 2 aut.) |
| DT : | Publication en série; Niveau analytique |
| SO : | The Journal of parasitology; ISSN 0022-3395; Coden JOPAA2; Etats-Unis; Da. 1997; Vol. 83; No. 5; Pp. 775-779; Bibl. 33 ref. |
| LA : | Anglais |
| EA : | Infective larvae (L3) of Strongylus vulgaris have limited energy stores for host finding and for infection. For transmission to occur, the larvae must have sufficient energy to (a) migrate onto grass, where they are ingested by their equine host (host finding), and (b) penetrate into the host gut. This study is designed to test the hypothesis that L3 larvae of S. vulgaris partition their energy stores between locomotory activity (used in host finding) and infection activity (penetration). Chronic locomotory activity was stimulated by incubating S. vulgaris L3 larvae at a constant temperature (38 C). After 8 days of treatment, locomotory activity ceased (exhaustion). Exhausted L3 larvae had significantly decreased total lipid when compared to controls (P < 0.05), but there was no decrease in levels of protein or carbohydrate. Lipids of S. vulgaris L3 larvae are comprised of 9 fatty acids, some of which are depleted in exhausted worms (14:0, 14:1, 16:0, 16:1, 18:1, 18:2), whereas others (18:0, 20:4, 24: 0) remain unchanged. These data suggest that specific fatty acids provide the energy source for locomotory activity in S. vulgaris. Exhausted L3 larvae were also less able to penetrate host cecal tissue in in vitro penetration assays when compared to controls (P < 0.05), suggesting that the depletion of individual fatty acids during locomotory activity also reduced infectivity. These data do not support the hypothesis that S. vulgaris L3 larvae partition their energy stores between host-finding and infection activities. A comparison of lipid storage profiles in the L3 larvae of 4 nematode species with similar transmission strategies (S. vulgaris, Strongylus edentatus, Strongylus equinus, and Haemonchus contortus) revealed similarities in the fatty acid composition of these species. These data suggest a relationship between transmission patterns and energy storage strategies in the L3 larvae of nematode parasites of vertebrates. |
| CC : | 002A12D03A |
| FD : | Parasite; Larve; Cycle évolutif; Transmission; Locomotion; Pouvoir infectant; Dépense énergétique; Lipide; Nematoda; Strongylus vulgaris |
| FG : | Nemathelminthia; Helmintha; Invertebrata |
| ED : | Parasite; Larva; Life history; Transmission; Locomotion; Infectivity; Energetic cost; Lipids; Nematoda |
| EG : | Nemathelminthia; Helmintha; Invertebrata |
| GD : | Transmission |
| SD : | Parásito; Larva; Ciclo evolutivo; Transmisión; Locomoción; Poder infectante; Costo energético; Lípido; Nematoda |
| LO : | INIST-2087.354000069882660010 |
| ID : | 98-0017325 |
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Pascal:98-0017325Le document en format XML
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Sukhdeo</name><affiliation><inist:fA14 i1="01"><s1>Department of Animal Sciences, Rutgers University</s1><s2>New Brunswick, New Jersey 08903</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">98-0017325</idno><date when="1997">1997</date><idno type="stanalyst">PASCAL 98-0017325 INIST</idno><idno type="RBID">Pascal:98-0017325</idno><idno type="wicri:Area/PascalFrancis/Corpus">000789</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Role of lipids in the transmission of the infective stage (L3) of Strongylus vulgaris (Nematoda: Strongylida)</title><author><name sortKey="Medica, D L" sort="Medica, D L" uniqKey="Medica D" first="D. L." last="Medica">D. L. 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Sukhdeo</name><affiliation><inist:fA14 i1="01"><s1>Department of Animal Sciences, Rutgers University</s1><s2>New Brunswick, New Jersey 08903</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14></affiliation></author></analytic><series><title level="j" type="main">The Journal of parasitology</title><title level="j" type="abbreviated">J. parasitol.</title><idno type="ISSN">0022-3395</idno><imprint><date when="1997">1997</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">The Journal of parasitology</title><title level="j" type="abbreviated">J. parasitol.</title><idno type="ISSN">0022-3395</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Energetic cost</term><term>Infectivity</term><term>Larva</term><term>Life history</term><term>Lipids</term><term>Locomotion</term><term>Nematoda</term><term>Parasite</term><term>Transmission</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Parasite</term><term>Larve</term><term>Cycle évolutif</term><term>Transmission</term><term>Locomotion</term><term>Pouvoir infectant</term><term>Dépense énergétique</term><term>Lipide</term><term>Nematoda</term><term>Strongylus vulgaris</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Infective larvae (L3) of Strongylus vulgaris have limited energy stores for host finding and for infection. For transmission to occur, the larvae must have sufficient energy to (a) migrate onto grass, where they are ingested by their equine host (host finding), and (b) penetrate into the host gut. This study is designed to test the hypothesis that L3 larvae of S. vulgaris partition their energy stores between locomotory activity (used in host finding) and infection activity (penetration). Chronic locomotory activity was stimulated by incubating S. vulgaris L3 larvae at a constant temperature (38 C). After 8 days of treatment, locomotory activity ceased (exhaustion). Exhausted L3 larvae had significantly decreased total lipid when compared to controls (P < 0.05), but there was no decrease in levels of protein or carbohydrate. Lipids of S. vulgaris L3 larvae are comprised of 9 fatty acids, some of which are depleted in exhausted worms (14:0, 14:1, 16:0, 16:1, 18:1, 18:2), whereas others (18:0, 20:4, 24: 0) remain unchanged. These data suggest that specific fatty acids provide the energy source for locomotory activity in S. vulgaris. Exhausted L3 larvae were also less able to penetrate host cecal tissue in in vitro penetration assays when compared to controls (P < 0.05), suggesting that the depletion of individual fatty acids during locomotory activity also reduced infectivity. These data do not support the hypothesis that S. vulgaris L3 larvae partition their energy stores between host-finding and infection activities. A comparison of lipid storage profiles in the L3 larvae of 4 nematode species with similar transmission strategies (S. vulgaris, Strongylus edentatus, Strongylus equinus, and Haemonchus contortus) revealed similarities in the fatty acid composition of these species. These data suggest a relationship between transmission patterns and energy storage strategies in the L3 larvae of nematode parasites of vertebrates.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0022-3395</s0></fA01><fA02 i1="01"><s0>JOPAA2</s0></fA02><fA03 i2="1"><s0>J. parasitol.</s0></fA03><fA05><s2>83</s2></fA05><fA06><s2>5</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Role of lipids in the transmission of the infective stage (L3) of Strongylus vulgaris (Nematoda: Strongylida)</s1></fA08><fA11 i1="01" i2="1"><s1>MEDICA (D. L.)</s1></fA11><fA11 i1="02" i2="1"><s1>SUKHDEO (M. V. K.)</s1></fA11><fA14 i1="01"><s1>Department of Animal Sciences, Rutgers University</s1><s2>New Brunswick, New Jersey 08903</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></fA14><fA20><s1>775-779</s1></fA20><fA21><s1>1997</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>2087</s2><s5>354000069882660010</s5></fA43><fA44><s0>0000</s0><s1>© 1997 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>33 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>98-0017325</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i2="1"><s0>The Journal of parasitology</s0></fA64><fA66 i1="01"><s0>USA</s0></fA66><fC01 i1="01" l="ENG"><s0>Infective larvae (L3) of Strongylus vulgaris have limited energy stores for host finding and for infection. For transmission to occur, the larvae must have sufficient energy to (a) migrate onto grass, where they are ingested by their equine host (host finding), and (b) penetrate into the host gut. This study is designed to test the hypothesis that L3 larvae of S. vulgaris partition their energy stores between locomotory activity (used in host finding) and infection activity (penetration). Chronic locomotory activity was stimulated by incubating S. vulgaris L3 larvae at a constant temperature (38 C). After 8 days of treatment, locomotory activity ceased (exhaustion). Exhausted L3 larvae had significantly decreased total lipid when compared to controls (P < 0.05), but there was no decrease in levels of protein or carbohydrate. Lipids of S. vulgaris L3 larvae are comprised of 9 fatty acids, some of which are depleted in exhausted worms (14:0, 14:1, 16:0, 16:1, 18:1, 18:2), whereas others (18:0, 20:4, 24: 0) remain unchanged. These data suggest that specific fatty acids provide the energy source for locomotory activity in S. vulgaris. Exhausted L3 larvae were also less able to penetrate host cecal tissue in in vitro penetration assays when compared to controls (P < 0.05), suggesting that the depletion of individual fatty acids during locomotory activity also reduced infectivity. These data do not support the hypothesis that S. vulgaris L3 larvae partition their energy stores between host-finding and infection activities. A comparison of lipid storage profiles in the L3 larvae of 4 nematode species with similar transmission strategies (S. vulgaris, Strongylus edentatus, Strongylus equinus, and Haemonchus contortus) revealed similarities in the fatty acid composition of these species. 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L.); SUKHDEO (M. V. K.)</AU><AF>Department of Animal Sciences, Rutgers University/New Brunswick, New Jersey 08903/Etats-Unis (1 aut., 2 aut.)</AF><DT>Publication en série; Niveau analytique</DT><SO>The Journal of parasitology; ISSN 0022-3395; Coden JOPAA2; Etats-Unis; Da. 1997; Vol. 83; No. 5; Pp. 775-779; Bibl. 33 ref.</SO><LA>Anglais</LA><EA>Infective larvae (L3) of Strongylus vulgaris have limited energy stores for host finding and for infection. For transmission to occur, the larvae must have sufficient energy to (a) migrate onto grass, where they are ingested by their equine host (host finding), and (b) penetrate into the host gut. This study is designed to test the hypothesis that L3 larvae of S. vulgaris partition their energy stores between locomotory activity (used in host finding) and infection activity (penetration). Chronic locomotory activity was stimulated by incubating S. vulgaris L3 larvae at a constant temperature (38 C). After 8 days of treatment, locomotory activity ceased (exhaustion). Exhausted L3 larvae had significantly decreased total lipid when compared to controls (P < 0.05), but there was no decrease in levels of protein or carbohydrate. Lipids of S. vulgaris L3 larvae are comprised of 9 fatty acids, some of which are depleted in exhausted worms (14:0, 14:1, 16:0, 16:1, 18:1, 18:2), whereas others (18:0, 20:4, 24: 0) remain unchanged. These data suggest that specific fatty acids provide the energy source for locomotory activity in S. vulgaris. Exhausted L3 larvae were also less able to penetrate host cecal tissue in in vitro penetration assays when compared to controls (P < 0.05), suggesting that the depletion of individual fatty acids during locomotory activity also reduced infectivity. These data do not support the hypothesis that S. vulgaris L3 larvae partition their energy stores between host-finding and infection activities. A comparison of lipid storage profiles in the L3 larvae of 4 nematode species with similar transmission strategies (S. vulgaris, Strongylus edentatus, Strongylus equinus, and Haemonchus contortus) revealed similarities in the fatty acid composition of these species. These data suggest a relationship between transmission patterns and energy storage strategies in the L3 larvae of nematode parasites of vertebrates.</EA><CC>002A12D03A</CC><FD>Parasite; Larve; Cycle évolutif; Transmission; Locomotion; Pouvoir infectant; Dépense énergétique; Lipide; Nematoda; Strongylus vulgaris</FD><FG>Nemathelminthia; Helmintha; Invertebrata</FG><ED>Parasite; Larva; Life history; Transmission; Locomotion; Infectivity; Energetic cost; Lipids; Nematoda</ED><EG>Nemathelminthia; Helmintha; Invertebrata</EG><GD>Transmission</GD><SD>Parásito; Larva; Ciclo evolutivo; Transmisión; Locomoción; Poder infectante; Costo energético; Lípido; Nematoda</SD><LO>INIST-2087.354000069882660010</LO><ID>98-0017325</ID></server></inist></record>Pour manipuler ce document sous Unix (Dilib)
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