EdenteV2, PascalFrancis, Corpus, bibRecord, 000323

The effect of ultrasound on osteogenesis in the vertically distracted edentulous mandible. A double-blind trial

Identifieur interne : 000323 ( PascalFrancis/Corpus ); précédent : 000322; suivant : 000324

The effect of ultrasound on osteogenesis in the vertically distracted edentulous mandible. A double-blind trial

Auteurs : J. Schortinghuis ; A. L. J. J. Bronckers ; J. Gravendeel ; B. Stegenga ; G. M. Raghoebar

Source :

International journal of oral and maxillofacial surgery [ 0901-5027 ] ; 2008.

RBID : Pascal:09-0017963

Descripteurs français

Pascal (Inist)
- Edentation, Exploration ultrason, Echographie, Chirurgie, Ultrason, Ostéogenèse, Mandibule, Etude double insu, Essai clinique, Traitement, Stomatologie.

English descriptors

KwdEn :
- Clinical trial, Double blind study, Echography, Edentulousness, Mandible, Osteogenesis, Sonography, Stomatology, Surgery, Treatment, Ultrasound.

Abstract

Whether low intensity pulsed ultrasound therapy stimulates osteogenesis in mandibular distraction was investigated in a double-blind trial. Nine patients underwent a vertical mandibular distraction over a distance of 5.1 ± 1.2 mm. Ultrasound or placebo therapy was started daily from the first day of distraction. After 46 ± 8.1 days consolidation, two endosseous implants were inserted and a transmandibular biopsy was taken. Ultrasonographs were taken regularly to follow osteogenesis inside the gap. There were no complications during the 44 ± 7.1 months of follow-up. Microradiographic measurements of the biopsies revealed no differences in the area of mineralized tissue in the distraction gap. The cranially distracted bone segment appeared significantly more radiolucent than the caudal bone. Histological examination showed large lacunae inside the cranially distracted bone segment, filled with clusters of osteoclasts and surrounded by clear tetracycline double labels. Within the distraction gap, woven bone was present, with no apparent differences between the treatment groups. Ultrasonographic follow-up revealed that osteogenesis inside the distraction gap progresses from 4 to 20 weeks post distraction, with no differences between the ultrasound and the placebo groups. In summary, ultrasound treatment does not appear to stimulate bone formation in the severely resorbed vertical distracted mandible.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A02	`01`			`@0 IJOSE9`
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A08	`01`	`1`	`ENG`	`@1 The effect of ultrasound on osteogenesis in the vertically distracted edentulous mandible. A double-blind trial`
A11	`01`	`1`		`@1 SCHORTINGHUIS (J.)`
A11	`02`	`1`		`@1 BRONCKERS (A. L. J. J.)`
A11	`03`	`1`		`@1 GRAVENDEEL (J.)`
A11	`04`	`1`		`@1 STEGENGA (B.)`
A11	`05`	`1`		`@1 RAGHOEBAR (G. M.)`
A14	`01`			`@1 Department of Oral and Maxillofacial Surgery, University of Groningen and University Medical Centre Groningen (UMCG) @3 NLD @Z 1 aut. @Z 4 aut. @Z 5 aut.`
A14	`02`			`@1 Department of Oral Cell Biology, Academic Centre for Dentistry @2 Amsterdam @3 NLD @Z 2 aut.`
A14	`03`			`@1 Department of Radiology, University of Groningen and University Medical Centre Groningen (UMCG) @3 NLD @Z 3 aut.`
A20				`@1 1014-1021`
A21				`@1 2008`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 16201 @5 354000184426170070`
A44				`@0 0000 @1 © 2009 INIST-CNRS. All rights reserved.`
A45				`@0 25 ref.`
A47	`01`	`1`		`@0 09-0017963`
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A61				`@0 A`
A64	`01`	`1`		`@0 International journal of oral and maxillofacial surgery`
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C01	`01`		`ENG`	@0 Whether low intensity pulsed ultrasound therapy stimulates osteogenesis in mandibular distraction was investigated in a double-blind trial. Nine patients underwent a vertical mandibular distraction over a distance of 5.1 ± 1.2 mm. Ultrasound or placebo therapy was started daily from the first day of distraction. After 46 ± 8.1 days consolidation, two endosseous implants were inserted and a transmandibular biopsy was taken. Ultrasonographs were taken regularly to follow osteogenesis inside the gap. There were no complications during the 44 ± 7.1 months of follow-up. Microradiographic measurements of the biopsies revealed no differences in the area of mineralized tissue in the distraction gap. The cranially distracted bone segment appeared significantly more radiolucent than the caudal bone. Histological examination showed large lacunae inside the cranially distracted bone segment, filled with clusters of osteoclasts and surrounded by clear tetracycline double labels. Within the distraction gap, woven bone was present, with no apparent differences between the treatment groups. Ultrasonographic follow-up revealed that osteogenesis inside the distraction gap progresses from 4 to 20 weeks post distraction, with no differences between the ultrasound and the placebo groups. In summary, ultrasound treatment does not appear to stimulate bone formation in the severely resorbed vertical distracted mandible.
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C03	`01`	`X`	`ENG`	`@0 Edentulousness @5 01`
C03	`01`	`X`	`SPA`	`@0 Edentación @5 01`
C03	`02`	`X`	`FRE`	`@0 Exploration ultrason @5 04`
C03	`02`	`X`	`ENG`	`@0 Sonography @5 04`
C03	`02`	`X`	`SPA`	`@0 Exploración ultrasonido @5 04`
C03	`03`	`X`	`FRE`	`@0 Echographie @5 05`
C03	`03`	`X`	`ENG`	`@0 Echography @5 05`
C03	`03`	`X`	`SPA`	`@0 Ecografía @5 05`
C03	`04`	`X`	`FRE`	`@0 Chirurgie @5 06`
C03	`04`	`X`	`ENG`	`@0 Surgery @5 06`
C03	`04`	`X`	`SPA`	`@0 Cirugía @5 06`
C03	`05`	`X`	`FRE`	`@0 Ultrason @5 07`
C03	`05`	`X`	`ENG`	`@0 Ultrasound @5 07`
C03	`05`	`X`	`SPA`	`@0 Ultrasonido @5 07`
C03	`06`	`X`	`FRE`	`@0 Ostéogenèse @5 08`
C03	`06`	`X`	`ENG`	`@0 Osteogenesis @5 08`
C03	`06`	`X`	`SPA`	`@0 Osteogénesis @5 08`
C03	`07`	`X`	`FRE`	`@0 Mandibule @5 09`
C03	`07`	`X`	`ENG`	`@0 Mandible @5 09`
C03	`07`	`X`	`SPA`	`@0 Mandíbula @5 09`
C03	`08`	`X`	`FRE`	`@0 Etude double insu @5 13`
C03	`08`	`X`	`ENG`	`@0 Double blind study @5 13`
C03	`08`	`X`	`SPA`	`@0 Estudio doble ciego @5 13`
C03	`09`	`X`	`FRE`	`@0 Essai clinique @5 14`
C03	`09`	`X`	`ENG`	`@0 Clinical trial @5 14`
C03	`09`	`X`	`SPA`	`@0 Ensayo clínico @5 14`
C03	`10`	`X`	`FRE`	`@0 Traitement @5 15`
C03	`10`	`X`	`ENG`	`@0 Treatment @5 15`
C03	`10`	`X`	`SPA`	`@0 Tratamiento @5 15`
C03	`11`	`X`	`FRE`	`@0 Stomatologie @5 16`
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N21				`@1 007`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Format Inist (serveur)

NO :	PASCAL 09-0017963 INIST
ET :	The effect of ultrasound on osteogenesis in the vertically distracted edentulous mandible. A double-blind trial
AU :	SCHORTINGHUIS (J.); BRONCKERS (A. L. J. J.); GRAVENDEEL (J.); STEGENGA (B.); RAGHOEBAR (G. M.)
AF :	Department of Oral and Maxillofacial Surgery, University of Groningen and University Medical Centre Groningen (UMCG)/Pays-Bas (1 aut., 4 aut., 5 aut.); Department of Oral Cell Biology, Academic Centre for Dentistry/Amsterdam/Pays-Bas (2 aut.); Department of Radiology, University of Groningen and University Medical Centre Groningen (UMCG)/Pays-Bas (3 aut.)
DT :	Publication en série; Niveau analytique
SO :	International journal of oral and maxillofacial surgery; ISSN 0901-5027; Coden IJOSE9; Pays-Bas; Da. 2008; Vol. 37; No. 11; Pp. 1014-1021; Bibl. 25 ref.
LA :	Anglais
EA :	Whether low intensity pulsed ultrasound therapy stimulates osteogenesis in mandibular distraction was investigated in a double-blind trial. Nine patients underwent a vertical mandibular distraction over a distance of 5.1 ± 1.2 mm. Ultrasound or placebo therapy was started daily from the first day of distraction. After 46 ± 8.1 days consolidation, two endosseous implants were inserted and a transmandibular biopsy was taken. Ultrasonographs were taken regularly to follow osteogenesis inside the gap. There were no complications during the 44 ± 7.1 months of follow-up. Microradiographic measurements of the biopsies revealed no differences in the area of mineralized tissue in the distraction gap. The cranially distracted bone segment appeared significantly more radiolucent than the caudal bone. Histological examination showed large lacunae inside the cranially distracted bone segment, filled with clusters of osteoclasts and surrounded by clear tetracycline double labels. Within the distraction gap, woven bone was present, with no apparent differences between the treatment groups. Ultrasonographic follow-up revealed that osteogenesis inside the distraction gap progresses from 4 to 20 weeks post distraction, with no differences between the ultrasound and the placebo groups. In summary, ultrasound treatment does not appear to stimulate bone formation in the severely resorbed vertical distracted mandible.
CC :	002B10C02; 002A23A; 002A04H15
FD :	Edentation; Exploration ultrason; Echographie; Chirurgie; Ultrason; Ostéogenèse; Mandibule; Etude double insu; Essai clinique; Traitement; Stomatologie
FG :	Pathologie dentaire
ED :	Edentulousness; Sonography; Echography; Surgery; Ultrasound; Osteogenesis; Mandible; Double blind study; Clinical trial; Treatment; Stomatology
EG :	Dental disease
SD :	Edentación; Exploración ultrasonido; Ecografía; Cirugía; Ultrasonido; Osteogénesis; Mandíbula; Estudio doble ciego; Ensayo clínico; Tratamiento; Estomatología
LO :	INIST-16201.354000184426170070
ID :	09-0017963

Links to Exploration step

Pascal:09-0017963

Le document en format XML

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<front><div type="abstract" xml:lang="en">Whether low intensity pulsed ultrasound therapy stimulates osteogenesis in mandibular distraction was investigated in a double-blind trial. Nine patients underwent a vertical mandibular distraction over a distance of 5.1 ± 1.2 mm. Ultrasound or placebo therapy was started daily from the first day of distraction. After 46 ± 8.1 days consolidation, two endosseous implants were inserted and a transmandibular biopsy was taken. Ultrasonographs were taken regularly to follow osteogenesis inside the gap. There were no complications during the 44 ± 7.1 months of follow-up. Microradiographic measurements of the biopsies revealed no differences in the area of mineralized tissue in the distraction gap. The cranially distracted bone segment appeared significantly more radiolucent than the caudal bone. Histological examination showed large lacunae inside the cranially distracted bone segment, filled with clusters of osteoclasts and surrounded by clear tetracycline double labels. Within the distraction gap, woven bone was present, with no apparent differences between the treatment groups. Ultrasonographic follow-up revealed that osteogenesis inside the distraction gap progresses from 4 to 20 weeks post distraction, with no differences between the ultrasound and the placebo groups. In summary, ultrasound treatment does not appear to stimulate bone formation in the severely resorbed vertical distracted mandible.</div>
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<s5>13</s5>
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<s5>13</s5>
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<s5>14</s5>
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<s5>15</s5>
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<fC03 i1="10" i2="X" l="ENG"><s0>Treatment</s0>
<s5>15</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Tratamiento</s0>
<s5>15</s5>
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<fC03 i1="11" i2="X" l="FRE"><s0>Stomatologie</s0>
<s5>16</s5>
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<fC03 i1="11" i2="X" l="ENG"><s0>Stomatology</s0>
<s5>16</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Estomatología</s0>
<s5>16</s5>
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<fC07 i1="01" i2="X" l="FRE"><s0>Pathologie dentaire</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Dental disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Diente patología</s0>
<s5>37</s5>
</fC07>
<fN21><s1>007</s1>
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<fN44 i1="01"><s1>OTO</s1>
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<fN82><s1>OTO</s1>
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<server><NO>PASCAL 09-0017963 INIST</NO>
<ET>The effect of ultrasound on osteogenesis in the vertically distracted edentulous mandible. A double-blind trial</ET>
<AU>SCHORTINGHUIS (J.); BRONCKERS (A. L. J. J.); GRAVENDEEL (J.); STEGENGA (B.); RAGHOEBAR (G. M.)</AU>
<AF>Department of Oral and Maxillofacial Surgery, University of Groningen and University Medical Centre Groningen (UMCG)/Pays-Bas (1 aut., 4 aut., 5 aut.); Department of Oral Cell Biology, Academic Centre for Dentistry/Amsterdam/Pays-Bas (2 aut.); Department of Radiology, University of Groningen and University Medical Centre Groningen (UMCG)/Pays-Bas (3 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>International journal of oral and maxillofacial surgery; ISSN 0901-5027; Coden IJOSE9; Pays-Bas; Da. 2008; Vol. 37; No. 11; Pp. 1014-1021; Bibl. 25 ref.</SO>
<LA>Anglais</LA>
<EA>Whether low intensity pulsed ultrasound therapy stimulates osteogenesis in mandibular distraction was investigated in a double-blind trial. Nine patients underwent a vertical mandibular distraction over a distance of 5.1 ± 1.2 mm. Ultrasound or placebo therapy was started daily from the first day of distraction. After 46 ± 8.1 days consolidation, two endosseous implants were inserted and a transmandibular biopsy was taken. Ultrasonographs were taken regularly to follow osteogenesis inside the gap. There were no complications during the 44 ± 7.1 months of follow-up. Microradiographic measurements of the biopsies revealed no differences in the area of mineralized tissue in the distraction gap. The cranially distracted bone segment appeared significantly more radiolucent than the caudal bone. Histological examination showed large lacunae inside the cranially distracted bone segment, filled with clusters of osteoclasts and surrounded by clear tetracycline double labels. Within the distraction gap, woven bone was present, with no apparent differences between the treatment groups. Ultrasonographic follow-up revealed that osteogenesis inside the distraction gap progresses from 4 to 20 weeks post distraction, with no differences between the ultrasound and the placebo groups. In summary, ultrasound treatment does not appear to stimulate bone formation in the severely resorbed vertical distracted mandible.</EA>
<CC>002B10C02; 002A23A; 002A04H15</CC>
<FD>Edentation; Exploration ultrason; Echographie; Chirurgie; Ultrason; Ostéogenèse; Mandibule; Etude double insu; Essai clinique; Traitement; Stomatologie</FD>
<FG>Pathologie dentaire</FG>
<ED>Edentulousness; Sonography; Echography; Surgery; Ultrasound; Osteogenesis; Mandible; Double blind study; Clinical trial; Treatment; Stomatology</ED>
<EG>Dental disease</EG>
<SD>Edentación; Exploración ultrasonido; Ecografía; Cirugía; Ultrasonido; Osteogénesis; Mandíbula; Estudio doble ciego; Ensayo clínico; Tratamiento; Estomatología</SD>
<LO>INIST-16201.354000184426170070</LO>
<ID>09-0017963</ID>
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The effect of ultrasound on osteogenesis in the vertically distracted edentulous mandible. A double-blind trial

The effect of ultrasound on osteogenesis in the vertically distracted edentulous mandible. A double-blind trial

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