EdenteV2, PascalFrancis, Checkpoint, bibRecord, 000508

Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load

Identifieur interne : 000508 ( PascalFrancis/Checkpoint ); précédent : 000507; suivant : 000509

Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load

Auteurs : Liliane Lins [Brésil] ; Herbert Almeida [Brésil] ; Ludmila Vitvisk [France] ; Theomira Carmo [Brésil] ; Raymundo Parana [Brésil] ; Mitermayer G. Reis [Brésil]

Source :

Journal of medical virology [ 0146-6615 ] ; 2005.

RBID : Pascal:06-0194450

Descripteurs français

Pascal (Inist)
- Virus hépatite C, Détection, Salive, Charge virale, Anatomopathologie, Dent pathologie, Hépatite virale C.

English descriptors

KwdEn :
- Anatomic pathology, Dental disease, Detection, Hepatitis C virus, Saliva, Viral hepatitis C, Viral load.

Abstract

Hepatitis C is a worldwide public health problem and its transmission is clearly associated with the parenteral route, however, the virus has also been isolated from other body fluids. Hepatitis C virus (HCV) RNA has been detected in saliva, yet the relationship between HCV and oral pathology is not clearly understood. Therefore, an investigation on HCV-RNA in saliva and its correlation with oral pathology was undertaken. Saliva and blood samples were collected from 50 anti-HCV positive patients and from 25 patients with non-HCV chronic liver disease. HCV-RNA was detected in all of the saliva samples from the HCV positive group. None of the saliva or serum samples from the non-HCV group were positive for HCV-RNA. The patients were examined for dental and oral health (dentate, partially dentate, edentulous, evidence of gum disease, or mucosal lesions); however, no correlation was found between HCV-RNA in saliva, oral health, and viral load. These results suggest that HCV-RNA presence in saliva is independent of the viral load and the oral pathology of HCV positive individuals.

Affiliations:

Brésil, France
Auvergne-Rhône-Alpes, Bahia, Rhône-Alpes
Lyon

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Hepatitis C is a worldwide public health problem and its transmission is clearly associated with the parenteral route, however, the virus has also been isolated from other body fluids. Hepatitis C virus (HCV) RNA has been detected in saliva, yet the relationship between HCV and oral pathology is not clearly understood. Therefore, an investigation on HCV-RNA in saliva and its correlation with oral pathology was undertaken. Saliva and blood samples were collected from 50 anti-HCV positive patients and from 25 patients with non-HCV chronic liver disease. HCV-RNA was detected in all of the saliva samples from the HCV positive group. None of the saliva or serum samples from the non-HCV group were positive for HCV-RNA. The patients were examined for dental and oral health (dentate, partially dentate, edentulous, evidence of gum disease, or mucosal lesions); however, no correlation was found between HCV-RNA in saliva, oral health, and viral load. These results suggest that HCV-RNA presence in saliva is independent of the viral load and the oral pathology of HCV positive individuals.</div>
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<fC03 i1="07" i2="X" l="SPA"><s0>Hepatitis virica C</s0>
<s5>15</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Hepacivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Hepacivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Hepacivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Flaviviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Flaviviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Flaviviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Stomatologie</s0>
<s5>13</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Stomatology</s0>
<s5>13</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Estomatología</s0>
<s5>13</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Virose</s0>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Viral disease</s0>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Virosis</s0>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Infection</s0>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Infection</s0>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Infección</s0>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Appareil digestif pathologie</s0>
<s5>16</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Digestive diseases</s0>
<s5>16</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Aparato digestivo patología</s0>
<s5>16</s5>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Foie pathologie</s0>
<s5>17</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Hepatic disease</s0>
<s5>17</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Hígado patología</s0>
<s5>17</s5>
</fC07>
<fN21><s1>121</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
<affiliations><list><country><li>Brésil</li>
<li>France</li>
</country>
<region><li>Auvergne-Rhône-Alpes</li>
<li>Bahia</li>
<li>Rhône-Alpes</li>
</region>
<settlement><li>Lyon</li>
</settlement>
</list>
<tree><country name="Brésil"><region name="Bahia"><name sortKey="Lins, Liliane" sort="Lins, Liliane" uniqKey="Lins L" first="Liliane" last="Lins">Liliane Lins</name>
</region>
<name sortKey="Almeida, Herbert" sort="Almeida, Herbert" uniqKey="Almeida H" first="Herbert" last="Almeida">Herbert Almeida</name>
<name sortKey="Carmo, Theomira" sort="Carmo, Theomira" uniqKey="Carmo T" first="Theomira" last="Carmo">Theomira Carmo</name>
<name sortKey="Carmo, Theomira" sort="Carmo, Theomira" uniqKey="Carmo T" first="Theomira" last="Carmo">Theomira Carmo</name>
<name sortKey="Lins, Liliane" sort="Lins, Liliane" uniqKey="Lins L" first="Liliane" last="Lins">Liliane Lins</name>
<name sortKey="Parana, Raymundo" sort="Parana, Raymundo" uniqKey="Parana R" first="Raymundo" last="Parana">Raymundo Parana</name>
<name sortKey="Reis, Mitermayer G" sort="Reis, Mitermayer G" uniqKey="Reis M" first="Mitermayer G." last="Reis">Mitermayer G. Reis</name>
<name sortKey="Reis, Mitermayer G" sort="Reis, Mitermayer G" uniqKey="Reis M" first="Mitermayer G." last="Reis">Mitermayer G. Reis</name>
<name sortKey="Reis, Mitermayer G" sort="Reis, Mitermayer G" uniqKey="Reis M" first="Mitermayer G." last="Reis">Mitermayer G. Reis</name>
</country>
<country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Vitvisk, Ludmila" sort="Vitvisk, Ludmila" uniqKey="Vitvisk L" first="Ludmila" last="Vitvisk">Ludmila Vitvisk</name>
</region>
</country>
</tree>
</affiliations>
</record>

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   |wiki=    Wicri/Santé
   |area=    EdenteV2
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   |clé=     Pascal:06-0194450
   |texte=   Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load
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This area was generated with Dilib version V0.6.32.
Data generation: Thu Nov 30 15:26:48 2017. Site generation: Tue Mar 8 16:36:20 2022

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Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load

Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load

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